• 제목/요약/키워드: Heterologous

검색결과 465건 처리시간 0.031초

Effects of Compound-A on the Early-Phase Anaphylactic Type Hypersensitivity

  • Lee, Ji-Yun;Lee, Jin-Hee;Kim, Tae-Doo;Sim, Sang-Soo;Kim, Chang-Jong
    • 대한약학회:학술대회논문집
    • /
    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
    • /
    • pp.125.3-126
    • /
    • 2003
  • Effect of Compound-A, a phenylpropanoid isolated from Arctium lappa fruit, on heterologous passive cutaneous anaphylaxis (HPCA), the release of histamine, and Phospholipase $A_2$ (PLA2) and phosphadiesterase (PDE) activities were studied by the method of Levine and Vaz. Anti-serum was prepared from ovalbumin (OA)-sensitized male Balb/c mouse at two weeks after the last challenge of OA and alumina gel. Heterologous PCA test in rats were carried out to determine the contents of leakaged pigment in the dorsal skin 30 minutes after i.v. injection of 0.2 ml of 1 % OA and 1 % Evans blue mixture (1:1). (omitted)

  • PDF