• Economic and Environmental Geology
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• v.45 no.5
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• pp.535-549
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• 2012

Main aspect of this study are to clarify mineral compositions on granites in Youngkwang-Naju area. These granites are is divided into four rock facies based on the geologic ages, mineralogical composition and chemical constituents, and texture : hornblende-biotite granodiorite, biotite granite, porphyritic granite and two mica granite. These granites constitude an igneous complex formed by a series of differentiation from cogenetic magma. In compressive stress field between the Ogcheon folded belt and the Youngnam massif, the foliated and undeformed granites had formed owing to heterogeneous distribution of stress. The geochemical data of study area indicate magma of these rocks would had been generated by melting in lower and middle crust. The major minerals of granitic rocks in study area are plagioclase, biotite, muscovite and hornblende. Plagioclase range in composition from oligoclase ($An_{19.3-27.7}$) to andesine ($An_{28.4-31}$), and shows normal zoning patterns, This uniformed composition indicated slow crystallization, and it is obvious that the growth of these crystal occurred before final consolidation of the magma. The Mg content of biotite are increases with increasing of $f_{O2}$ and grade of differentiation, changing from phlogopite to siderophyllite. Its $Al^{iv}$/$Al^{total}$ ratios are propertional to bulk rock alumina content. Muscovite is primary in origin with high content of $TiO_2$, and Its composition correspond to celadonitic muscovite. Hornblende indicated calc amphibole group ($(Ca+Na)_{M4}{\geq}1.43$, $Na_{M4}<0.67$). and consolidation pressure of granitic body by geobarometer of Hammerstrume and Zen show 11.3~17.2 Km.

• Journal of Korean Society of Forest Science
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• v.103 no.2
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• pp.165-174
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• 2014

This study was conducted to investigate composition of understory vegetation and indicator species by altitude and slope azimuth in Mt. Gyebang designated as Protected Area for Forest Genetic Resource Conservation and National Park. Tracheophytes were 350 taxa; 80 families, 203 genera, 303 species, 38 varieties, 5 forma and 4 sub-species in research area. The species of greatest importance value were Tripterygium regelii (9.143%), Acer pseudosieboldianum (7.594%), Symplocos chinensis for. pilosa (6.347%) in the shrub layer and were Sasa borealis (8.653%), Isodon excisus (2.936%) and Carex siderosticta (2.897%). In the herb layer as a result of NMS analysis, the distribution range of the major species were found to be affected by the altitude (shrub layer: $R^2$ > 0.3, herb layer: $R^2$ > 0.6). The result of plexus diagram analysis showed that Acer pseudosieboldianum was associated with Magnolia sieboldii, Acer barbinerve, Euonymus oxyphyllus etc. in the shrub layer; Meehania urticifolia was associated with Aconitum jaluense, Veratrum oxysepalum, Prunus padus etc. in the herb layer. The significant indicator species were analyzed for 60 species by the altitude and investigated for 30 species in accordance with the slope azimuth. As a consequence of MRPP, interspecies composition along the altitude group was heterogeneous and the species composition according to the azimuth slope was extremely different between the NE and SW.

• Journal of Pharmaceutical Investigation
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• v.33 no.2
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• pp.113-120
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• 2003

Drug interactions with food, on occasion, lead to serious nutritional and functional changes in the body as well as alternations of pharmacological effect. It, therefore, should be necessary to take drug interactions with food into consideration for effective and safe therapeutics. Diabetes mellitus is a heterogeneous group of disorders characterized by abnormal glucose homeostasis, resulting in hyperglycemia, and is associated with increased risk of micovascular, macrovascular, and neuropathic complications. However, the precise mechanism of diabetes mellitus remains unclear. Three basic objectives in the care of diabetic patients are maintaining optimal nutrition, avoiding hypo- or hyperglycemia and preventing complications. The purpose of this study was to investigate thε effect of Laminaria japonica diet on the absorption, distribution, metabolism and excretion of glipizide which are frequently used in the treatment of diabetes. Diabetic rats induced by streptozotocin were employed in this study. Blood concentrations of oral hypoglycemic agents were measured by HPLC and resultant pharmacokinetic parameters were calculated by RSTRIP. The mechanisms of drug interaction with food were evaluated on the basis of pharmacokinetic parameters such as $k_{a},\;t_{1/2},\;C_{max},\;t_{max}$ and AUC. Administration of glipizide in normal rats treated with Laminaria japonica diet showed significant increase in AUC, $k_{a},\;t_{1/2},\;t_{max}$ and decrease in $C_{max}$, compared to those without Laminaria japonica diet. This might result from adsorption of glipizide on components of Laminaria japonica, causing delayed absorption. Administration of glipizide in diabetic rats treated with Laminaria japonica diet showed significant increase in $t_{1/2}\;and\;t_{max}$, and decrease in $C_{max}$, compared to those without Laminaria japonica diet. This might also result from adsorption of glipizide on components of Laminaria japonica, causing delayed absorption and flattened blood concentration of glipizide. The oral glucose test showed that Laminaria japonica diet could lower blood glucose level probably through either inhibiting the activity of disaccharidases, intestinal digestive enzymes, or delaying the absorption of glucose. More studies should be followed to fully understand pharmacokinetic changes of glipizide caused by long-term Laminaria japonica diet.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.2
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• pp.221-231
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• 2013

Exchanging personal health information(PHI) is an essential process of healthcare services using information and communication technology. But the process have the inherent risk of information disclosure, so the PHI should be protected to ensure the reliability of healthcare services. In this paper, we designed encryption module for wearable personal health devices(PHD). A main goal is to guarantee that the real-time encoded and transmitted PHI cannot be allowed to be read, revised and utilized without user's permission. To achieve this, encryption algorithms as DES and 3DES were implemented in modules operating in Telos Rev B(16bit RISC, 8Mhz). And the experiments were performed in order to evaluate the performance of encryption and decryption using vital-sign measured by PHD. As experimental results, an block encryption was measured the followings: DES required 1.802 ms and 3DES required 6.683 ms. Also, we verified the interoperability among heterogeneous devices by testing that the encrypted data in Telos could be decoded in other machines without errors. In conclusion, the encryption module is the method that a PHD user is given the powerful right to decide for authority of accessing his PHI, so it is expected to contribute the trusted healthcare service distribution.

• Anxiety and mood
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• v.5 no.1
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• pp.29-35
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• 2009

Background : In spite of the worldwide relevance of obsessive-compulsive disorder Ed-highlight : Unclear. Perhaps consider changing word choice. (OCD), there are considerable differences in prevalence, sex ratio, comorbidity patterns, and sociodemographic correlates. Data on subclinical OCD have been sparse to date. Methods : Data stemmed from the Korea Epidemiologic Catchment Area (KECA) study which had been carried out from April to December 2001. Korean versions of DSM-IV adapted Composite International Diagnostic Interview were administered to a representative sample of 6275 persons aged 18-64 living in the community. DSM-IV based criteria for subclinical OCD were applied. Results : The lifetime prevalence rates for OCD and subclinical OCD were 0.8% and 6.6%, respectively. In both OCD and subclinical OCD, the rates for males and females were not statistically different. OCD was demonstrated to be associated with depressive disorder, bipolar disorder, social phobia, generalized anxiety disorder, and alcohol and nicotine dependence. Additionally, subclinical OCD was associated with posttraumatic stress and somatoform disorders. Comorbidity rates in subclinical OCD were lower than those in OCD. Conclusions : The lifetime prevalence rate for OCD was less than 1% in the Korean general population. Age distribution and comorbidity patterns suggest that subclinical OCD represents a broad and heterogeneous syndrome and not simply a milder form of OCD.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.2
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• pp.405-410
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• 2018

Distribution of a series of procedure for establishment and revision for various instructions on information security for public institutions and diversified process of performance system following the compliance with the instruction are applied to the integrated procedure that any revision or change has led to the studies that are applied on the basis of all environment requirements and the facilitation of such studies in the integrated procedure for the entire information security. However, as the difference of possessing the work territory for each institution, maintaining and securing the security with the heterogeneous type for subject, the information still displays the issues to link to a series of process to the procedure to secure the foregoing as stability, In addition, the notice should be made by the public institutions for the result structured and notified on the basis of budget and the additional time and expenses for re-distributing to the private institutions would be another issue for the part to accomplish the purpose of such study. Therefore, under this study, the subject of information security of similar institutions should be sorted out and statistically classified, and it proposes the integration procedure through a series of diversity and multi-change process and summarize the same in the proposed procedure to engage in studies to secure the optimal stability.

• Journal of Life Science
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• v.16 no.5
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• pp.812-827
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• 2006

To investigate the population structure and geographic distance among anchovies (Engraulis japonicus) in Korea, we compared and analyzed the mitochondrial DNA control region sequences (227 bp) of anchovies from 12 localities in inshore and offshore waters. The sequence analysis of 84 individuals showed 29 haplotypes, ranging in sequence divergence by pairwise comparisons from 0.3% to 3.5% (1 bp-12 bp). E9 haplotype of anchovies were found largely in inshore waters and also in offshore waters, which was regarded as the major source in Korean waters (58.3%). However, E26, E27, E28, and E29 haplotypes were found in westsouthern (locality 10, four among 7). Phylogenetic analysis using PHYLIP was divided into two clades (clade A and B). Most of the haplotypes, excluding E26, E27, E28, and E29, were strongly supported by bootstrap analysis (>75%), whereas the relationship between clade A and B was weakly supported by bootstrap analysis (51%). High levels of genetic diversity were found; haplotype diversity (H)=0.75-1.00, and nucleotide diversity $({\pi})=0.015-0.0244$. Analysis of $F_{ST}$ between populations in inshore waters ranged in 0.01-0.05, whereas those of offshore waters ranged in 0.01-0.58. A high gene flow occurred in inshore (Nm=22.61-34.22) and offshore (Nm=11.57-45.67) populations. The distribution of mitochondrial DNA haplotypes between westsouthern and other populations was suggestive of significantly different differentiation ($F_{ST}$=0.20-0.59, p<0.05; d=0.52, p=0.00; ${\phi}=0.02-0.41$, p＜0.05). These results suggested that the overall anchovy population in the Korean peninsula caused considerable migration due to the mitochondrial gene flow between inshore and offshore populations to form a genetically homogenous and panmictic structure, although a heterogeneous population was found in this study.

• Environmental and Resource Economics Review
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• v.19 no.4
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• pp.853-874
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• 2010

This study examines the acceptability of nuclear facilities using the latent class analysis. Even though, nuclear power is useful in terms of economic and energy security aspects, it is very difficult to expand the existing nuclear power plants or build a new one. Many studies analysed the cause of unacceptability of nuclear facilities but it has not been focused how large portion of people are divided pro and con. It is very important to know the distribution of people by the attitude toward nuclear facilities in order to meet the long term National Energy Plan. Through the latent class analysis with 1,025 respondents, people are classified into three groups(favor-class, support-class, opposition-class). The favor-class is the largest group which has moderate good attitudes toward the nuclear facilities in terms of economy, cleanness. and necessity but concerns a little about safety. The second largest group is the support-class which comprises 1/4 portion of people. The people in the class show the aggressive support for the nuclear facilities. 15% of the respondents belong to the opposition-class which show the negative attitudes to expansion of neclear facilities. In order to increase the acceptability of nuclear faculties, the most urgent work for the government to do is to less people's concern about nuclear safety.

• The Journal of the Petrological Society of Korea
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• v.11 no.1
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• pp.30-48
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• 2002

Phenocrysts with rapakivi texture are easily observed in Bangeojin granite. The rapakivi texture is composed of inner pinkish alkali feldspars and white-colored mantling plagioclase. The Bangeojin granite distinctively includes lots of mafic microgranular enclaves and can be divided into five rock facies: (1) enclave-poor granite (EPG); (2) enclave-rich granite (ERG); (3) mafic microgranular enclave (MME); (4) hybrid zone between mafic microgranular enclave and granite (HZ); (5) hybrid zone-like enclaves (HLE). The rapakivi textures are observed in these five rock facies with no difference in shape and size. Plagioclase mantle commonly shows dendritic texture that is an important indicator to know the rapakivi genesis. The mantling texture would indicate supercooling condition during magma solidification process. In addition, mafic microgranular enclaves would imply the magma mingling environment. The magma mixing process had possibly caused the mantling texture. An abundance of rapakivi phenocrysts in HZ and the influxing phenomenon of the phenocrysts into MME support that there were physical chemical exchanges during the mingling. And this model of the magma mixing/mingling explain well the heterogeneous distribution of the rapakivi phenocrysts in the five rock facies. Therefore the rapakivi textures in the Bangeojin granite would have been formed by magma mixing process.

• Korean Journal of Microbiology
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• v.27 no.1
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• pp.1-9
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• 1989

The locations of 5' ends as well as the splicing pattern of viral poly A(-) 19S RNA from monkey cells infected with SV40 were determined by a modification of primer extension method. The 5' end of this RNA mapped at the major cap site at nucleotide residue 325, used most frequently by SV40 late RNAs. The intron from nt.373 to nt.558 was removed as the ordinary cytoplasmic poly A(+) 19S RNA. The 3'end of this RNA was very heterogeneous and distributed over 1 kb upstream of polyadenylation site, as determined by S1 nuclease mapping. The reason for this normally initiated and spliced RNA to accumulate in the nucleus was investigated. In order to test whether the presence of unused 3' splice region on this RNA caused such subcellular distribution, cells were transfected with SV40 mutant KNA containing deletion around 3' splice site. The RNA deleted of 3' splice region accumulated mainly in the cytoplasm. This accumulation did not result from the increased stability of the RNA due to the deletion, since the wild type and mutant RNAs exhibited similar half lives after chase with actinomycin D. Therefore it is likely that the 19S spliced RNA is hindered from being transported into the cytoplasm due to some pre-splicing complexes formed at the unused 3' splice site.