• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.61-70
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• 2006

3-D S-wave velocity model in the southern Korean Peninsula is investigated by using the joint inversion of receiver functions and surface-wave dispersion. A peninsula average Rayleigh-wave phase velocity in the 10-150 seconds range and tomographic estimates of the Rayleigh and Love wave group velocities in the 0.5-20 seconds period range determined using a $12.5{\times}12.5\;km$ grid for the southern part of the peninsula are used for the inversion. Receiver functions were determined from broadband (STS-2), short-period (SS-1) and acceleration (Episensor) channels of 95 stations. The dense distribution of the stations in the Peninsula permits us to examine the 3-D crustal structure in detail. The inversion result shows the variation and characteristics of S-wave velocity in the crust and upper mantle of the southern Korean Peninsula very well.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.41-50
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• 2006

The crustal structure of Korean Peninsula have been investigated by analyzing group velocity dispersion data of surface wave. Cross.correlation of seismic background motions (Campillo and Paul, 2003; Shapiro et al., 2005) has been applied to estimate the short.period Rayleigh. and Love.wave group velocity dispersion characteristics of the region. Standard processing procedures were applied to the cross.correlation, except that signal whitening was used in place of one.bit sampling equalize power in signals from different times. Multiple.filter analysis was used to extract the group velocities from the estimate Green's functions, which were then use to image the spatially varying dispersion at periods between 0.5 and 20 seconds. The tomographic inversion technique used inverted all periods simultaneously to provide a smooth dispersion curve as a function of period in addition to the usual smooth spatial image for a given period. The Gyeongsang Basin in the southeastern part of the peninsula is clearly resolved with lower group velocities.

• World Technopolis Review
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• v.1 no.4
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• pp.276-286
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• 2013

"Federal investments into the future of a region" - pushing economy in the right direction or throwing tax money into a black hole? Hot-headed contentions keep circulating within politics and economy discussing the effect of technology centers and their sustainability within a region. Start-up support and technological infrastructure with the auxiliary service of well developed sector-oriented clusters as a fertile soil for successful networks are an undeniable advantage of well organised technology centers. Sceptic contemporaries still hold against that in order to implement such a center millions of federal funds for infrastructure and operation are invested. What output of this tax money is verifiable in the long run? The case of Dortmund provides substantial food for this necessary and relevant discussion. Now, after 27 years of history of the TechnologieZentrumDortmund, TZDO for short, a positive balance can be drawn. This is not just a matter of personal belief and stance. Fortunately, a recent study on the economic effects of the TZDO on the whole region was performed by the Center of Applied Economy Research M$\ddot{u}$nster, Germany (Gundel and Luttmann 2008). The result is clear and measurable: the TZDO has shown to be of great impact on the positive development of a whole region. This paper presents an account of the approach of the TechnologieZentrumDortmund and its current strategy and mode of operation to reach an utmost of effectiveness of personal and pecuniary input in establishing economic success for the region of Dortmund. An immense change of minds, employment opportunities and a massive structural change of the whole region were some of the ambitious aims that had to be reached and that are achieved to a large extent.

• Restorative Dentistry and Endodontics
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• v.46 no.4
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• pp.60.1-60.8
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• 2021

Objectives: The aim of this study was to verify the match between 5 shades of composites from different manufacturers with a shade guide and among the systems using a portable spectrophotometer. Materials and Methods: Shade measurements were performed on specimens of Z350 XT (3M ESPE), Charisma Diamond (Heraeus Kulzer GmbH), Esthet X-HD (Dentsply Caulk), and Empress Direct (Ivoclar-Vivadent) for shades A1, A2, A3, B1, and C3 using a Vita Easyshade spectrophotometer (Vita Zahnfabrik) against a white background. Corresponding shades of Vitapan Classical (Vita Zahnfabrik) guide were measured likewise and shade variation (ΔE) was calculated based on International Commission on Illumination L^*a^*b^* parameters. The ΔE of the composites in each shade was compared by one-way analysis of variance and Tukey's post hoc test (α = 0.05). Results: All composites presented ΔE > 3.7 compared with the shade guide. Variation in shades A3, B1, and C3 was significantly different for all composites. ΔE of Z350 XT was significantly lower for A1 than for the other shades, whereas ΔE of Z350 XT and Charisma Diamond were significantly lower for A2 than for the other shades. Conclusions: No composite shade matched with the shade guide. Equivalent shades of the restorative composite from different manufacturers may show clinically noticeable ΔE.

• Korean Circulation Journal
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• v.53 no.2
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• pp.69-91
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• 2023

Cardio-oncology is an emerging multi-disciplinary field, which aims to reduce morbidity and mortality of cancer patients by preventing and managing cancer treatment-related cardiovascular toxicities. With the exponential growth in cancer and cardiovascular diseases in Asia, there is an emerging need for cardio-oncology awareness among physicians and country-specific cardio-oncology initiatives. In this state-of-the-art review, we sought to describe the burden of cancer and cardiovascular disease in Asia, a region with rich cultural and socio-economic diversity. From describing the uniqueness and challenges (such as socio-economic disparity, ethnical and racial diversity, and limited training opportunities) in establishing cardio-oncology in Asia, and outlining ways to overcome any barriers, this article aims to help advance the field of cardio-oncology in Asia.

• International Journal of Stem Cells
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• v.16 no.3
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• pp.293-303
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• 2023

Background and Objectives: The physiological oxygen tension in fetal brains (~3%, physioxia) is beneficial for the maintenance of neural stem cells (NSCs). Sensitivity to oxygen varies between NSCs from different fetal brain regions, with midbrain NSCs showing selective susceptibility. Data on Hif-1𝛼/Notch regulatory interactions as well as our observations that Hif-1𝛼 and oxygen affect midbrain NSCs survival and proliferation prompted our investigations on involvement of Notch signalling in physioxia-dependent midbrain NSCs performance. Methods and Results: Here we found that physioxia (3% O₂) compared to normoxia (21% O₂) increased proliferation, maintained stemness by suppression of spontaneous differentiation and supported cell cycle progression. Microarray and qRT-PCR analyses identified significant changes of Notch related genes in midbrain NSCs after long-term (13 days), but not after short-term physioxia (48 hours). Consistently, inhibition of Notch signalling with DAPT increased, but its stimulation with Dll4 decreased spontaneous differentiation into neurons solely under normoxic but not under physioxic conditions. Conclusions: Notch signalling does not influence the fate decision of midbrain NSCs cultured in vitro in physioxia, where other factors like Hif-1𝛼 might be involved. Our findings on how physioxia effects in midbrain NSCs are transduced by alternative signalling might, at least in part, explain their selective susceptibility to oxygen.

• Journal of the Korean Geophysical Society
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• v.9 no.3
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• pp.209-217
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• 2006

The major continental blocks in NE-Asia are the North China Block and the South China Blo, which have collided, starting from the Korean peninsula. The suture zone in NE China between two blocks is well defined from the QinIing-Dabie-Orogenic Belt to the Jiaodong (Sulu) Belt by the geological and geophysical interpretation. The discovery of high pressure metamorphic rocks in the Hongsung area of the Korean peninsula can be used to estimate the suture zone. This indicates that the suture zone in the Jiaodong Belt might be extended to Hongsung area. However, due to the lack of geological and geophysical data over the Yellow sea, the extension of the suture zone to the Korean peninsula across the Yellow Sea is obscure. To find out the tectonic relationship between NE China and the Korean peninsula it is necessary to complete U-ie homogeneous geophysical dataset of NE Asia, which can be provided by satellite observations. The CHAMP lithospheric magnetic field (MF3) and CHAMP-GRACE gravity field, combined with surface measured data, allow a much more accurate in-ference of tectonic structures than previously available. The CHAMP magnetic anomaly map reveals significant magnetic lows in the Yellow Sea near Nanjing and Hongsung, where are characterized by gravity highs on U-ie CHAMP-GRACE gravity anomaly map. To evaluate the depth and location of poten-tial field anomaly causative bodies, the Euler Deconvolution method is implemented. After comparing the two potential field solutions with the simplified geological map containing tectonic lines and the distribution of earthquakes epicenters, it is found that the derived structure boundaries of both are well coincident with the seismic activities as well as with the tectonic lineaments. The interpretation of the CHAMP satellite magnetic and GRACE satellite gravity datasets reveal two tectonic boundaries in U-ie Yellow Sea and the Korean peninsula, indicating U-ie norttiern and southern margins of the suture zone between the North China Block and the South China Block. The former is extended from the Jiaodong Belt in East China to the Imjingang Belt on the Korean peninsula, the later from Nanjing, East China, to Hongsung, the Korean peninsula. The tectonic movement in or near the suture zone might be responsible for the seismic activities in the western region of the Korean Peninsula and the development of the Yellow Sea sedimentary basin.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.1
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• pp.101-116
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• 2019

Technology-based start-up is important in that it encourages innovation, facilitates the development of new products and services, and contributes to job creation. Technology-based start-up activates entrepreneurship when appropriate support is provided within the ecosystem. Thus, understanding the technology-based start-up ecosystem is crucial. The purpose of this study is as follows. First, in Herrmann et al.'s(2015) study, we compare and analyze the ecosystem of each country by selecting representative regions such as Silicon Valley, Tel Aviv, London and Singapore which have the highest ranking in the start-up ecosystem. Second, we try to deeply understand the start-up ecosystem based on in-depth interviews with various stakeholders such as VC investors, start-ups, support organizations, and professors related to the Korean start-up ecosystem. Finally, based on the results of the study, we suggest development and activation of Korean technology-based start-up ecosystem. As a result, the Seoul start-up ecosystem showed a positive evaluation of government support compared to other advanced countries. In addition, it was confirmed that the ratio of tele-work and start-up company working experience of employees was higher than other countries. On the other hand, in Seoul, It was confirmed that overseas market performance, human resource diversity, attracting investment, hiring technological engineers, and the ratio of female entrepreneurs were lower than those of overseas advanced countries. In addition, according to the results of the interview analysis, Seoul was able to find that start-up ecosystems such as individual angel investors, accelerators, support institution, and media are developing thanks to the government's market-oriented policy support. However, in order for this development to continue, it is necessary to improve the continuous investment system, expansion of diversity, investment return system, and accessibility to the global market. A discussion on this issue is presented.

• Asia Marketing Journal
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• v.13 no.3
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• pp.55-77
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• 2011

This study investigate the interaction effects of bundle price discount framing and message framing on consumer's attitude of bundle component. Although each effect of bundle price discount framing and message framing has been explored individually, few attempts have been made to invest them jointly. This study tests the interaction effects of bundle price discount framing and message framing on consumer's evaluation of bundle component. Moreover, this research focuses on consumer's evaluation of individual bundle component while the existing research on bundling primarily focused on consumer's evaluation of the bundle. Prior research suggests that consumers are sensitive to the framing of prices and discounts in the presentation of the bundle offer. For example, there is considerable evidence that partitioning or consolidating the prices of a bundle can influence the attractiveness of the bundle offer. Similarly, there is evidence that an equivalent price reduction to the overall bundle, one of the individual products in the bundle, or distributed among the individual products in the bundle can alter the perceived attractiveness of the offer (e.g. Chakravarti, Krish, Paul, and Srivastava 2002; Hamilton and Srivastava 2008; Janiszewski and Cunha 2004; Johnson, Herrmann and Bauer 1999; ; Morwitz, Greenleaf, and Johnson 1998; Yadav 1994; 1995). In line with these earlier research, this research suggests that the bundle type can influence the consumer's evaluation of bundle component. There are two types of bundle - mixed-leader bundle and mixed-joint bundle. In mixed-leader bundling, the price of one of the two products is discounted when the other product is purchased at the regular price. In mixed-joint bundling, a single price is set when the two product are purchased jointly. This study supposes that the teeth whitening product is the leader product in a mixed-leader bundle. So bundle price discount framing is manipulated such as "Buy the teeth whitening product (regular price \80,000) and get 50% discount on the functional toothpaste(regular price \40,000), special set price \100,000" or "Buy the functional toothpaste and the teeth whitening product as a set and get discount for the set, special set price \60,000". Message framing is manipulated through the product claims described in an advertising bill. The positive framing presents that "Over 95% of users achieved the expected 2-3 shades of improvement in two weeks" where as the negative framing presents "less than 5% of users did not achieve the expected 2-3 shades of improvement in two weeks". This study uses hypothetical brand name of the teeth whitening product and the functional toothpaste This study is based on a 2x2 factorial design with bundle discount framing (mixed-leader bundle vs. mixed-joint bundle) and massage framing (positive vs. negative). The dependant variables are consumer's perceived quality and attitude of the teeth whitening product The data reveals that two dependant variables are correlated, so the data is analyzed with two-way MANOVA. This research explores the significant interaction effect of bundle discount framing and message framing on consumer's perceived quality and attitude of the teeth whitening product. When the message framing is positive, consumer's perceived quality and attitude of the teeth whitening product is higher in mixed-leader bundle than mixed-joint bundle condition. However, when the message framing is negative, consumer's evaluation is higher in mixed-joint bundle than mixed-leader bundle. The author explains this result by stating that consumers are less likely to use heuristics such as price-quality association and value discounting hypothesis(Raghubir 2004) in the negative message framing condition. Additionally, consumer's perceived risk of the teeth whitening product in the negative message framing condition can be more reduced by the bundle partner(e.g. the toothpaste) in mixed-joint bundle than mixed-leader bundle. Based on the results, marketing managers are advised to use different bundle type based on message framing of their product.