• Korean Journal of Acupuncture
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• 제20권3호
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• pp.115-128
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• 2003

Objectives and methods :　Study the anti-cancer, anti-metastasis and immune response improvement effects of Herbal-acupuncture with Evodiae Fructus infusion solution, we injected Evodiae Fructus infusion solution into Zusanli(St36) of C57BL/6 mouse which is corresponding to human Zusanli(St36). We observed its effect on the number of $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in mouse PBMCs, the number of the pulmonary colony , MST and ILS of C57BL/6 mice implanted intravenously with B16-F10 melanoma. Results and Conclusions : The spleen cells proliferation of the sample groups treated with EDR-HAS extract has increased significantly compared with that of the control group. The percentage of the $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in C57BL/6 mouse PBMCs of the sample groups treated with EDR herbal-acupuncture has increased compared with that of the control group. The lung colony number of the sample groups treated with EDR herbal-acupuncture has decreased significantly compared with that of the control group. MST and ILS of the sample groups treated with EDR herbal-acupuncture have increased significantly compared with those of the control group.

• Journal of Acupuncture Research
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• 제28권6호
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• pp.69-83
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• 2011

Objectives : This study aimed to evaluate the effects of Malvae Semen herbal-acupuncture (MS-HA) at$KI_{10}$($Eumgok$) on nephritis induced by lipopolysaccharide (LPS) in rat. Methods : Rats with nephritis induced by LPS, were treated with Malvae Semen herbal-acupuncture(MS-HA) injection at $KI_{10}$. Two control groups, N.P group and Saline group, were treated with 26 gauge needle at $KI_{10}$, 3 times a week. In Saline group, normal saline was injected at $KI_{10}$. To evaluate the effects of Malvae Semen Herbal-acupuncture at $KI_{10}$ on nephritis in rats, WBC, Neutrophils in blood, BUN, Creatinine, TNF-a, CINC-1 in serum, urinal volume, creatinine, total protein in urine and renal TNF-a, renal tissue were analyzed. Results : MS-HA at $KI_{10}$ significantly reduced WBC and neutrophil in blood, TNF-${\alpha}$ in serum of LPS-stimulated rats. MS-HA at $KI_{10}$ significantly reduced total protein level in urine. MS-HA at $KI_{10}$ reduced accumulation of neutrophil in renal tissue of LPS-stimulated rats. Conclusions : Taken together, MS-HA at $KI_{10}$ has a therapeutic effect on nephritis in LPS-stimulated rat. Therefore, it is suggested that MS-HA at $KI_{10}$ may be an useful therapeutics for nephritis in clinical field.

• Journal of Acupuncture Research
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• 제27권2호
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• pp.105-113
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• 2010

Objectives : This study was performed to analyze the quality of Ojeok-san extract powders distributed in Korea. Methods : HPLC analyses of Ojeok-san decoction produced in laboratory and 8 kinds of Ojeok-san extract powders were done. Also, quantity analyses of paeoniflorin in Paeonia lactiflora, Glycyrrhizin in Glycyrrhiza uralensis, alkaloid in Ephedra sinica, Hesperidin in Citrus unshiu Markovich, and cinnamic acid in Cinnamomum cassia Blume were performed to investigate the accurate content of 6 kinds of Ojeok-san extract powders. Results : In the pattern analysis, the peaks were compared. The content of components in herbal extract powders was 14.7 to 15.8% of that of decoction in average. The range was measured from 8.5 to 25.7%. The pattern comparison showed significant differences among the pharmaceutical companies' products. As for the quantity analysis, one of herbal extract powder contained insufficient amount of Paeonia lactiflora components and one of herbal extract powder was in short of Ephedra sinica components. All of the others contained more than standard component(over 90%). Conclusions : Because herbal extract powders are also medicine, standardized manufacturing methods and consistent quality management are necessary. Therefore exaction and operation of national standards and various researches to improve the quality management of herbal extract powders is urgent.

• Journal of Acupuncture Research
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• 제20권3호
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• pp.141-153
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• 2003

To study the effects of anti-cancer, anti-metastasis and immune response improvement of herbal-acupuncture with Eclipta prostrata diffuse herba infusion solution(ELP-HAS), we injected ELP-HAS into Chok-samni(St36) of C57BL/6 mice implanted intravenously with B16-F10 melanoma. We have reached the following conclusion through the effect on the number of $CD25^+/CD4^+$, $CD8^+/CD3e^+$, $CD69^+/B220^+$, $NK1.1+/CD3e^+$ cells in mouse PBMCs, the effect on the pulmonary colony number, and the effect on MST(Median Survival Time) and ILS(Increase of Life Span) of C57BL/6 mice implanted intravenously with B16-F10 melanoma The results were obtained as follows: 1. In the experiment groups treated with ELP(Eclipta prostrata) Herbal-Acupuncture, the spleen cell proliferation in Balb/c mouse was significantly increased compared with control group. 2. In the experiment groups treated with ELP(Eclipta prostrata) Herbal-Acupuncture, the percentage of $CD25^+/CD4^+$, $CD8^+/CD3e^+$, $CD69^+/B220^+$, $NK1.1^+/CD3e^+$ cells in C57Bl/6 mouse PBMCs was increased compared with control group. 3. In the experiment groups treated with ELP(Eclipta prostrata) Herbal-Acupuncture, the pulmonary colony number of C57BL/6 mice implanted intravenously with B16-F10 melanoma was decreased significantly compared with control group. 4. In the experiment groups treated with ELP(Eclipta prostrata)Herbal-Acupuncture, MST(Median Survival Time) and ILS(Increase of Life Span) of C57BL/6 mice implanted intravenously with B16-F10 melanoma were increased significantly compared with control group.

• Journal of Acupuncture Research
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• 제19권3호
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• pp.192-206
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• 2002

Objective : This study is performed for the purpose of examining into the efficacy of the scolopendrid(Scolopendra morsitans L) which has been used among the Korean people for the H.I.V.D of lumbar spine. Methods & Results : Using the herbal acupuncture made of scolopendrid(Scolopendra morsitans L), we treated the 20 H.I.V.D patients for 1 week and operated 4 pre and post treatment test ; D.I.T.I, 6 kinds of physical test, Oswestry disability index, and self-conscious pain rate. Trough the test, we saw 43-95% of efficacy rate in each test. And all of the 7 acupuncture point in D.I.T.I, Oswestry disability index and self-conscious pain rate test showed statistically valuable change. Conclusion : We brought to the conclusion that the scolopendrid herbal acupuncture has possibility to be efficient to cure the H.I.V.D patients. So we suggest the possibility to use this new remedy for the H.I.V.D.

• Journal of Acupuncture Research
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• 제21권2호
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• pp.275-286
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• 2004

Objective : This study is designed to find out the effects of Cervus elaphus Herbal acupuncture on osteoarthritis in knee joint. Methods : We investigated 15 cases of patients with osteoarthritis in knee joint that arevisited in hospital of Dong-Shin Korean Traditional Medicine. We evaluated knee joint function that before and after its treatment by Lyshoim score and satisfaction of treatment by Baumgaertner nine point sacle and VAS score. Results : The sex distinction with a disease caused much more female than male at the ratio of 1 to 2.75 in the proportion of male to female. Jobs is mainly ranked with a sitting position jobs and a housewife. Approximately 73.3% of cases before our hospital have ever treated at the other clinics or hospitals. According to Lyshoim score, before treatment is 54.87 and after is 63.29, that showd stisfacally meaningful increase. According to VAS score, before treatment is 10 and after is 44.6. In evaluating of satisfaction, good are 73.2% according to Baumgaertner nine point sacle. Conclusion : According to the results, Cervus elaphus Herbal acupuncture may be effects on the increase of knee joints function and the decrease of pain on osteoarthritis in knee joint.

• 대한약침학회지
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• 제4권1호
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• pp.103-104
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• 2001

This study was done to observe the effect on the local thermal changes of herbal acupuncture on D.I.T.I.. The objects of this study are as follows; If there are remarkable local thermal changes between pre and post herbal acupuncture therapy on D.I.T.I.or not. If there are those, We examine how long that changes are maintained, what the adequate interval is on herbal acupuncture therapy, and what the reaction in a .local or whole body are on that therapy Materials and Methods : To study the local thermal changes in herbal acupuncture therapy, D.I.T.I. was used. Determination of this analysis periods are pre and post-therapy(1 hour, 24hours, 48hours and 7days later). The study group was divided into three groups(comprised 23 students in oriental medical college, Woosuk University). One was NS(Normal Saline) group, another was CF(CARTHAMI SEMEN) group and the other was BU(FEL URSI + BENZOAR BOVIS) group. The Herbal Acupunture solution was injected 0.2ml divide into 0.05ml at tile P'ungmun(B12), P'yesu(B13), Pubun(B41), Paek'o(B42) 4 points. Then, in order to analyze the clinical form, we have observed response of 23 students whenever we checked the thermal changes of their after perfoming Results : The results were obtained as follows ; 1. There is no significant dermatothermal changes at NS group and CF group, but BU group have remarkable changes in 24, 48, 72 hours. 2. From post-therapy 1 hour to 48 hours, there is a significant change (P<0.01) at NS-BU group and CF-BU group, But there is none 7 days later. 3. In the analysis of whole or local body reaction, local pain appears at NS group(22%), CF group(11%), BU group(91%), discomfort reaction appears at CF group(14%), BU group(30%). BU groilp has feel vertigo(13%), drowsy (70%) and pain in action(52%). 4. In the analysis of the duration of physic진 reaction, BU group is most lately maintained. Conclusions : These results suggest that in the physical reaction of herbal acupuncture solutions, BU solution is more sensitive than CF solution or NS.

• 대한약침학회지
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• 제9권3호통권21호
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• pp.131-138
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• 2006

Objective : The aim of this study was to investigate the effect of HHT(Hwangryunhaedoktang Herbal-Acupuncture) on functional headache. Methods : 26 clinical experiment participants who experienced functional headache were gathered. The qualified patients were classified in two group, Normal saline injection group and Hwangryunhaedoktang Herbal-Acupuncture group. NS group was injected normal saline and HHT group was injected HHT at GB20, GB21, LI4. Treatment was applied 4 times every second day. The effects of both groups were analyzed using VAS scores and BPI(Brief Pain Inventory). Result : The VAS pain scores improved in both groups. the BPI scores decreased only in HHT group. The decrease rate of VAS scores and BPI scores was larger in HHT group. Conclusion : These results provided that HHT group is more effective than NS group. For clearly comparing the Effect of Hwangryunhaedoktang Herbal-Acupuncture on functional headache, it is need more sample's number and more treatment's duration.

• 대한약침학회지
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• 제9권3호통권21호
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• pp.89-95
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• 2006

Objectives : This study is to research if any acupucture points are more effective, when Mahuang-chuanwu herbal acupucture is applied to the theatment of obesity. Methods : We searched oriental medical literatures and papers. Results : 1. Mahuang-chuanwu Herbal Acupuncture consists of distilled water of Ma-hunag and Chuan-wu, and it has the following effects : channel-warming, cold-dispering and eliminating damp. therefore it is applied to the treatment of obesity. 2. The acupuncture points, which have effects of channel-warming, cold-dispering and eliminating damp, are six : Kwanwon(Cv4), Kihae(CV6), Changmun(Liv13), Chok-samni(St36), Chung-wan(Cv12), Chonchu(St25). And Kwanwon(Cv4), Kihae(CV6), Changmun(Liv13), Chung-wan(Cv12), Chonchu(St25) locate on the abdomen. 3. Morbidly obese people, especially those in which their bellies are very large, are so because often the binding properties of the Taemaek(G26) have weakend. therefore Taemaek(G26) will be more effecive than Changmun(Liv13) that locate on right below the free end of the 11th rib, at the lateral side of the chest. 4. Mahuang-chuanwu Herbal Acupuncture will be most effective on the treatment of obesity with cold and damp as additional treatment, when it is injected into Kwanwon(Cv4), Kihae(CV6), Chonchu(St25), Taemaek(G26).

• Journal of Acupuncture Research
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• 제22권2호
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• pp.203-210
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• 2005

Objectives : The purpose of this study was to investigate anti-cancer effects of various ginseng herbal acupuncture in mice and expression of cytokine mRNA. Methods: Anti-cancer effects of various ginseng herbal acupuncture were tested by measuring the increase of life span of mice suffering from peritoneal cancer induced by Sarcoma-180, and expression of mRNA manifestation using RT-PCR. The results are as follows: Results: 1. Increase of life span of mice suffering from peritoneal cancer induced by Sarcoma-180 was measured for anti-cancer effects. As a result, 115% increase was shown in the cultivated wild ginseng group, 11.1% increase in the red ginseng group, and no increase was detected in either white ginseng and fresh ginseng groups. 2. Measuring the expression of cytokine mRNA manifestation, expression of $interferon-{\gamma}$ was slightly increased in the cultivated wild ginseng group compared to the control group, but manifestation of interleukin-10 was slightly decreased. 3. For the red ginseng, white ginseng, and fresh ginseng experiment groups II, IL-2, IL-4, $INF-{\gamma}$, and IL -10 all showed increase suggesting possible error occurring during the test process. Conclusion: From the results obtained in this study, we can reason that the ginseng we use may not match the ginseng cited in the texts of the past. Anti-cancer effects of cultivated wild ginseng can be more potent than those of white and fresh ginseng.