• Title/Summary/Keyword: Hemodynamic

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Renal Action of Domperidone in Dog (돔페이돈의 신장작용)

  • 고석태;최홍석
    • YAKHAK HOEJI
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    • v.37 no.6
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    • pp.561-570
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    • 1993
  • Renal action of domperidone known as dopamine receptor blocker and effect of domperidone on renal function of dopamine were investigated in dog. Domperidone, when administered into vein, produced diuretic action by the improvement of renal hemodynamic state, when given into a renal artery, elicited diuretic action accompanied with natriuresis in only experimental kidney, whereas domperidone given into carotid artery exhibited antidiuretic action by the decrease of Na$^{+}$ excretion in urine. Diuretic action of dopamine was not influenced by domperidone given into vein or into a renal artery, was blocked by domperidone given into carotid artery. Above results suggest that domperidone produced both peripheral diuretic and central antidiuretic action, and domperidone do not block diuretic action by renal hemodynamic improvement of dopamine in kidney.

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Hemodynamic Evaluation of Monoleaflet Polymer Valve (단엽식 고분자판막의 혈역학적 성능평가)

  • 김상현;장병철
    • Journal of Biomedical Engineering Research
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    • v.16 no.1
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    • pp.61-66
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    • 1995
  • We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane. To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medicals prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volllme and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate.

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Development of Image Post-processing System for the Cerebral Perfusion Information Mapping of MR Image (MR영상의 뇌관류 정보 Mapping을 위한 영상후처리 시스템개발)

  • 이상민;강경훈;장두봉;김광열;김영일;신태민
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.1
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    • pp.131-138
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    • 2000
  • This paper works on development of an algorithm for mapping of cerebral perfusion parameters using the gamma-variate curve fitting. The signal intensity variate curve according to time measured in each pixel of perfusion MRI is nonlinear, and various hemodynamic parameters are not computed accurately. Levenberg-Marquardt algorithm(LMA), nonlinear optimum algorithm with high convergent speed and stability, is used to compute them. That is, the signal intensity variate curve is fitted by the gamma-variate function. Various hemodynamic parameters - Cerebral Blood Volume(C.B.V), Mean Transit Time(M.T.T), Cerebral Blood Flow(C.B.F), Time-to-Peak(T.T.P), Bolus Arrival Time(B.A.T), Maximum Slope(M.S) - are computed using LMA.

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Hemodynamic Effects on Artery-Graft Anastomotic Intimal Hyperplasia (혈류의 유동이 혈관-인조혈관 접속부 혈관 내막 세포증식에 미치는 영향)

  • 이계한
    • Journal of Biomedical Engineering Research
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    • v.15 no.2
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    • pp.143-150
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    • 1994
  • Wall shear rate or stress is believed to be a major hemodynamic variable influencing atherosclerosis and artery-graft anastomic intimal hyperplasia. The purpose of this study is to verify the effects of radial wall motion, artery-graft compliance and diameter mismatch, and impedance phase angle on the wall shear rate distribution near an end-to-end artery-graft anastomosis model. The results show that radial wall motion of the elastic artery model lowers the mean wall shear rates under pulsatile flow condition by 15 to 20 % comparing to those under steady flow condition at the same mean flow rate. Impedance phase angle seems to have small effects on the mean and amplitude of the wall shear rate distribution. In order to study the effects of compliance and diameter mismatch on the wall shear rates, two models are studied-Model I has 6% and Model I has 6% and Model II has 11% smaller graft diameter. Divergent geometry caused by diameter mismatch near the distal sites reduces the mean wall shear rates significantly, and this low shear region is believed to be prone to intimal hyperplasia.

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Measurement of Event-related Hemodynamic Responses on Motor Cortex Measured by Near-infrared Spectroscopy (근적외선 분광 분석법을 이용한 운동령에서의 사건 기반 산소 포화도 변화 신호 측정)

  • Lee, Dong-Chul;Shin, Jae-Young;Kim, Ji-Hyun;Jeong, Ji-Chai
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.7
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    • pp.1049-1055
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    • 2012
  • We measure the hemodynamic responses during the 4 kinds of tasks on the motor cortex in the right and left human brain by using near-infrared spectroscopy. The experimental results show that the change of concentration of oxy-hemoglobin is larger than that of deoxy-hemoglobin and the change of concentration of chromophores induced by finger and arm related task show more activations than that of leg.

Clinical Application of SPECT and PET in CerebroVascular Disease (뇌혈관질환에서 SPECT와 PET의 임상적 응용)

  • Ra, Young-Shin
    • The Korean Journal of Nuclear Medicine
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    • v.37 no.1
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    • pp.1-12
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    • 2003
  • Single photon emission computed tomography(SPECT) and positron emission tomography(PET) are modern imaging techniques that allow for both qualitative and quantitative assessment of hemodynamic changes in cerebrovascular diseases. SPECT has been becoming an indispensable method to investigate regional cerebral blood flow because equipment and isotope are easily available in most general hospitals. Acetazolamide stress SPECT has also been proved to be useful to evaluate the cerebrovascular reserve of occlusive cerebrovascular diseases and to select surgical candidate. PET has gained wide spread clinical use in the evaluation of the hemodynamic and metabolic consequences of extracranial or intracranial arterial obstructive disease despite its complexity and limited availability. PET has been established as an invaluable tool in the pathophysilogy investigation of acute ischemic stroke. The potentials, limitations, and clinical applications of SPECT and PET in various cerebrovascular diseases will be discussed in this article with reviews of literatures.

Non-Permanent Transcatheter Proximal Renal Artery Embolization for a Grade 5 Renal Injury with Delayed Recanalization and Preserved Renal Parenchymal Enhancement

  • Jairam, Abhishek;King, Bradley;Berman, Zachary;Rivera-Sanfeliz, Gerant
    • Journal of Trauma and Injury
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    • v.34 no.3
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    • pp.198-202
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    • 2021
  • Super-selective renal artery embolization is an increasingly popular technique for the management of traumatic, low-grade renal trauma. When performed in distal arterial branches, this intervention enables tissue preservation and arrest of hemorrhage, but it may not be practical in cases of multifocal, high-grade renal injuries. In such cases, surgical nephrectomy remains the more common treatment modality to ensure hemodynamic control. We present the unique case of a patient who presented in hemorrhagic shock following a major trauma that resulted in a grade 5 renal injury treated with complete renal artery embolization using Gelfoam, resulting in hemodynamic stabilization. Interestingly, imaging 1 month after embolization revealed residual enhancement of the inferior pole of the kidney, suggesting reconstitution of flow and partial renal salvage. Ultimately, transcatheter "nephrectomy" with careful selection of a temporary embolic agent may serve as a safe and efficient alternative to surgical nephrectomy with the added possibility of preserving partial renal perfusion and function in the emergent setting.

Hemorrhagic Shock in a Patient with a Morel-Lavallée Lesion Combined with Active Arterial Bleeding without Fracture

  • Lim, Eic Ju;Oh, Jong-Keon;Cho, Jae-Woo;Sakong, Seungyeob;Cho, Jun-Min
    • Journal of Trauma and Injury
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    • v.34 no.1
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    • pp.61-65
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    • 2021
  • A Morel-Lavallée lesion is a closed degloving injury caused by traumatic separation of the skin and subcutaneous tissue from the underlying fascia. However, since physicians tend to focus on treating the bone fracture, hemodynamic instability accompanying a Morel-Lavallée lesion can sometimes be overlooked. We report the case of a hemodynamically unstable 73-year-old man who had a Morel-Lavallée lesion of the thigh, but no femur fracture. Angiography showed active bleeding from the muscular branch of the right deep femoral artery, which was then successfully embolized.