• Journal of Society of Preventive Korean Medicine
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• v.10 no.1
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• pp.123-140
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• 2006

This experiment was carried out to study on the safety assessment of Pinus densiflora Siebold et Zuccarini for Hebal-acupuncture. SD rats and ICR mice were used for acute toxicity test, the results were summerized as follows; 1. In rats and mice, $LD_{50}$ value could not be measured. 2. There were no abnormal finding in acute toxicity test treated Pinus densiflora Siebold et Zuccarini for Hebal-acupuncture.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.3
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• pp.103-118
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• 2017

Objectives : The purpose of this study is to analyze recent research trend on pathology of Meniere's Disease and review the results in Korean Medicine. Methods : We searched MEDLINE on the title "Meniere's Disease" and "pathology" in recent 5 years and searched OASIS with KISS on the title "Meniere's Disease". Results : We found 21 studies on MEDLINE, 9 studies on OASIS and KISS about Meniere's Disease. The results are as follow. 1. In western medicine, the pathology of Meniere's disease is supposed to be related with endolymphatic hydrops and autoimmunity. The causes of endolymphatic hydrops are studied in various viewpoints such as disorder of endolymph drainage and homeostasis abnormality of endolymph. And autoimmunity is assumed to be associated with genetic factor. 2. In Korean medicine, Meniere's disease were mainly treated with acupuncture and hebal medicine. Conclusions : Korean medicinal approaches on pathology of Meneire's disease can be significant in view of endolymphatic hydrops. And on the basis of those outcomes, much more studies have to be researched for Korean medicinal treatment of Meneire's disease.