• 한국기계가공학회지
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• 제14권4호
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• pp.73-84
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• 2015

Electricity generation using fossil fuels has caused environmental pollution. To solve this problem, research on new renewable energy sources (solar, wind power, geothermal heat, etc.) to replace fossil fuels is ongoing. These devices are able to generate power consistently. However, they have many weaknesses, such as high installation costs and limits to possible setup environments. Therefore, an active study on piezoelectric harvesting technology that is able to surmount the limitations of existing energy technologies is underway. Piezoelectric harvesting technology uses the piezoelectric effect, which occurs in crystals that generate voltage when stress is applied. Therefore, it has advantages, such as a wider installation base and lower technological costs. In this study, a piezoelectric harvesting device imitating seaweed, which has a consistent motion caused by fluid, is used. Thus, it can regenerate electricity at sea or on a bridge pillar, which has a constant turbulent flow. The components of the device include circuitry, springs, an electric generator, and balancing and buoyancy elements. Additionally, multiphysics analysis coupled with fluid, structure, and piezoelectric elements is conducted using COMSOL Multiphysics to evaluate performance. Through this program, displacement and electric power were analyzed, and the actual performance was confirmed by the experiment.

• BMB Reports
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• 제39권5호
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• pp.530-536
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• 2006

Thermal conformational changes of human serum albumin (HSA) in phosphate buffer, 10 mM at pH = 7 are investigated using differential scanning calorimetric (DSC), circular dichroism (CD) and UV spectroscopic methods. The results indicate that temperature increment from $25^{\circ}C$ to $55^{\circ}C$ induces reversible conformational changes in the structure of HSA. Conformational change of HSA are shown to be a three-step process. Interestingly, melting temperature of the last domain is equal to the maximum value of fever in pathological conditions, i.e. $42^{\circ}C$. These conformational alterations are accompanied by a mild alteration of secondary structures. Study of HSA-SDS (sodium dodecyl sulphate) interaction at $45^{\circ}C$ and $35^{\circ}C$ reveals that SDS affects the HSA structure at least in three steps: the first two steps result in more stabilization and compactness of HSA structure, while the last one induces the unfolding of HSA. Since HSA has a more affinity for SDS at $45^{\circ}C$ compared to $35^{\circ}C$, It is suggested that the net negative charge of HSA is decreased in fever, which results in the decrease of HSA-associated cations and plasma osmolarity, and consequently, heat removal via the increase in urine volume.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 추계학술대회논문집B
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• pp.499-504
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• 2001

A validation of a 3D CFD model for predicting local subcooling of moderator in the vicinity of calandria tubes in a CANDU reactor is performed. The small scale moderator experiments performed at Sheridan Park Experimental Laboratory(SPEL) in Ontario, Canada[1] is used for the validation. Also a comparison is made between previous CFD analyses based on 2DMOTH and PHOENICS, and the current model analysis for the same SPEL experiment. For the current model, a set of grid structures for the same geometry as the experimental test section is generated and the momentum, heat and continuity equations are solved by CFX-4.3, a CFD code developed by AEA technology. The matrix of calandria tubes is simplified by the porous media approach. The standard $k-\varepsilon$ turbulence model associated with logarithmic wall treatment and SIMPLEC algorithm on the body fitted grid are used and buoyancy effects are accounted for by the Boussinesq approximation. For the test conditions simulated in this study, the flow pattern identified is a buoyancy-dominated flow, which is generated by the interaction between the dominant buoyancy force by heating and inertial momentum forces by the inlet jets. As a result, the current CFD moderator analysis model predicts the moderator temperature reasonably, and the maximum error against the experimental data is kept at less than $2.0^{\circ}C$ over the whole domain. The simulated velocity field matches with the visualization of SPEL experiments quite well.

• Bulletin of the Korean Chemical Society
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• 제31권9호
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• pp.2649-2655
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• 2010

$PKC{\delta}$-catalytic V5 Heptapeptide (FEQFLDI, FP7) interacts with heat shock protein 27 (HSP27) and inhibits HSP27-mediated resistance to cell death against various stimuli including radiation therapy. Here, we prepared radio-iodinated heptapeptide and further investigated its uptake properties in HSP27 expression cells. Peptide sequence of FP7 and a negative control peptide (WSLLEKR, QP7) was modified by substituting their C-terminus residue to tyrosine (FP6Y and QP6Y) to label radio-iodine. Iodinated peptides were confirmed by LC mass analysis with cold iodine reaction mixture. Accumulation of [$^{125}I$]iodo-FP6Y and [$^{125}I$]iodo-QP6Y in NCI-H1299 cell line, with higher level of HSP27, and NCI-H460 cell line, with lower level of HSP27, was measured by NaI(Tl) scintillation counter. The modification of substituting C-terminus residue of FP7 to tyrosine (FP6Y) did not affect its interaction with HSP27. Accumulation of [$^{125}I$]iodo-FP6Y in NCI-H1299 cells was 3 fold higher than in NCI-H460 cells. The novel radio-iodinated FP6Y would be used as a tracer for targeting HSP27 protein.

• BMB Reports
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• 제34권4호
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• pp.355-364
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• 2001

Major human Nucleoside diphosphate kinases (NDPKs) exist as hetero-oligomers, consisting of NDPK-A and NDPK-B, rather than homo-oligomer. To investigate their biological function depending on the oligomeric structure in vivo, we characterized the biochemical properties of cellular NDPK. Cellular NDPKs, which are made up of a unique combination of isoforms, were purified from human erythrocyte and placenta. We found that cellular NDPK and recombinant isoforms NDPKs have their own distinct biochemical properties in autophosphorylation, stability toward heat or urea, and DNA binding. Cellular NDPK was found to have unique characteristics rather than the expected additive properties of recombinant isoforms. The mutations in the dimeric interface of NDPK-B (R34G, N69H or K135L) caused defective DNA binding and simultaneously reduced the enzymatic stability These results suggest that the oligomeric interaction could play a major role in the stability of catalytic domain and might be related to the regulation of various cellular functions of NDPK.

• 대한기계학회논문집A
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• 제38권12호
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• pp.1359-1365
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• 2014

본 연구에서는 측추력기 구성품인 Shutter의 열구조 안전성을 평가하기 위해 단방향 유체-구조 연성해석을 수행하였다. Shutter는 측추력기에서 노즐을 개방시키기 위한 구동 토크와 연소가스의 고온, 고압 열하중을 받는 부품으로 연소가 진행되는 동안 열구조 안전성을 확보하여야만 한다. 유체-구조 연성해석을 위해 측추력기의 연소시간동안 내부 유동장에서 발생하는 연소가스의 압력 및 온도 분포, 대류 열전달계수값을 유동해석을 통해 도출하였고, 이 결과 값을 맵핑 방식을 이용하여 열구조 해석의 하중조건으로 부가하였다. 연소시간동안 Shutter에서 발생되는 최대 응력 및 취약위치, 온도분포를 단위 시간 단위로 분석하여 온도에 따른 소재의 인장강도 값과 비교하여 열구조 안전성을 평가 하였다. 또한 반경 방향 변형량을 분석하여 셔터와 노즐목 간의 적정 간극을 설정하는 근거로 활용하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제5권2호
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• pp.275-278
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• 1992

One hundred sixty three (163) animals were used in $2{\times}2$ and $3{\times}2$ factorial experiment in randomized complete block design (RCBD) to determine the effect of clitoral stimulation during timed inseminations on the fertility of Philippine swamp buffaloes (carabaos). There were 3 separate trials conducted with two treatment groups per trial : control and with 30 second clitoral stimulation after each insemination. Parity, tone of uterus and site of semen deposition were also used as criteria in subdividing the main groups. The pregnancy rates of animals that received clitoral stimulation were significantly (p<0.05 or p<0.01) higher than those of control for both caraheifers (52.98 vs 31.41%) and caracows (52.68 vs 27.07%) ; under all uterine conditions : tone 1 (53.33 vs 31.75%), tone 2 (35.83 vs 22.82%) and tone 3 (75.65 vs 42.44%) ; and in both site of semen placement, cervix (43.99 vs 22.85%) and uterus (60.92% vs 37.81%). Fertility was also significantly (p<0.05) higher when semen was deposited in the uterus (49.37%) than in the cervix (33.42%). Interaction effect was insignificant. Clitoral stimulation should be utilized as a routine procedure following artificial insemination in carabaos.

• Asian-Australasian Journal of Animal Sciences
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• 제26권9호
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• pp.1205-1217
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• 2013

Pigs require energy for maintenance and productive purposes, and an accurate amount of available energy in feeds should be provided according to their energy requirement. Available energy in feeds for pigs has been characterized as DE, ME, or NE by considering sequential energy losses during digestion and metabolism from GE in feeds. Among these energy values, the NE system has been recognized as providing energy values of ingredients and diets that most closely describes the available energy to animals because it takes the heat increment from digestive utilization and metabolism of feeds into account. However, NE values for diets and individual ingredients are moving targets, and therefore, none of the NE systems are able to accurately predict truly available energy in feeds. The DE or ME values for feeds are important for predicting NE values, but depend on the growth stage of pigs (i.e., BW) due to the different abilities of nutrient digestion, especially for dietary fiber. The NE values are also influenced by both environment that affects NE requirement for maintenance ($NE_m$) and the growth stage of pigs that differs in nutrient utilization (i.e., protein vs. lipid synthesis) in the body. Therefore, the interaction among animals, environment, and feed characteristics should be taken into consideration for advancing feed energy evaluation. A more mechanistic approach has been adopted in Denmark as potential physiological energy (PPE) for feeds, which is based on the theoretical biochemical utilization of energy in feeds for pigs. The PPE values are, therefore, believed to be independent of animals and environment. This review provides an overview over current knowledge on energy utilization and energy evaluation systems in feeds for growing pigs.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2003년도 하계학술대회 논문집 Vol.4 No.1
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• pp.278-281
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• 2003

The p-CIn2Te4 single crystal was grown in the three-stage vertical electric furnace by using Bridgman method. The quality of the grown crystal has been investigated by the x-ray diffraction and the photoluminescence measurements. From the photoluminescence spectra of the as-grown CdIn2Te4 crystal and the various heat-treated crystals, the (Do, X) emission was found to be the dominant intensity in the photoluminescence spectrum of the CdIn2Te4:Cd, while the (Ao, X) emission completely disappeared in the CdIn2Te4:Cd. However, the (Ao, X) emission in the photoluminescence spectrum of the CdIn2Te4:Te was the dominant intensity like an as-grown CdIn2Te4 crystal. These results indicated that the (Do, X) is associated with VTe acted as donor and that the (Ao, X) emission is related to VCd acted as acceptor, respectively. The p-CdIn2Te4 crystal was found to be obviously converted into the n-type after annealing in the Cd atmosphere. The origin of (Do, Ao) emission and its TO phonon replicas is related to the interaction between donors such as VTe or Cdint, and accepters such as VCd or Teint. Also, the In in the CdIn2Te4 was confirmed not to form the native defects because it existed in the stable form of bonds.

• 한국항공우주학회지
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• 제34권7호
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• pp.79-88
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• 2006

본 논문에서는 대와동모사를 이용하여 모형 가스터빈 연소기에서 난류 예혼합연소의 선회 유동구조와 화염특성이 검토되었다. 비정상 화염 거동을 모사하기 위하여 G-방정식 화염편 모델이 적용되었다. 결과로서, 입구 선회수 증가에 따른 코너 및 중앙 재순환 유동이 뚜렷한 차이를 보이며, 화염의 길이도 점차 감소됨을 확인 할 수 있었다. 또한 강선회 조건에서 역화현상의 원인이 확인되었다. 정확한 비정상 화염거동의 모사를 위하여, 연소실 내 음향파 거동의 예측성능이 우선적으로 검토되었으며, 스텝 모서리 근처에서 생성된 와동이 화염면 변동에 가장 큰 영향을 주고 있음을 알 수 있었다. 마지막으로 비정상 화염-와동 상호작용에 대한 해석을 통해 선회와 음향파의 전개로부터 생성된 와동의 진동이 화염면 및 열발생의 변동과 밀접하게 관련되어짐을 체계적으로 규명하였다.