• Journal of Chest Surgery
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• 제13권1호
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• pp.21-25
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• 1980

This study was attempted to evaluate the effectiveness of cold cardioplegic solution [group B] compared with that of intermittent aortic cross clamping [group A]. 1. In group A, two dogs recovered spontaneous heart beat without using defibrillator and one case was used defibrillator once. In group B, four dogs recovered the spontaneous heart beat even without defibrillator and in one animal the defibrillator was used three times. 2. There was no significant difference in serum electrolyte [Na+, Ca2+, Cl- ] between group, but K+ level was decreased in both group. 3. The group A showed more increasing in serum LDH activity than group B. 4. The postoperative myocardial ATP level was $2.35{\pm}0.10$ ${\mu}$M/Gm. of wet weight in control group, $1.46{\pm}0.16$${\mu}$M/Gm. of wet weight in group A [60.2% of control group], and $1.80{\pm}0.14$${\mu}$M/Gm. of wet weight in group B [76.8% of control group].

• Journal of Chest Surgery
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• 제32권11호
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• pp.984-988
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• 1999

Background: Donor-specific blood transfusion(DSBT) before organ transplantation has been demonstrated to prolong allograft survival; the mechanism of this effect has remained unclear. Only a few researches have been performed on this subject in our country. Material and Method: To investigate the effect of DSBT, we selected 5 donor recipient combinations using rats of pure strain such as PVG, ACI, and LEW. One ml of donor whole blood was transfused to each recipient through the femoral vein 7 days prior to transplantation. The donor heart was transplanted to the recipient's abdominal vessels heterotopically using modified Ono and Lindsey's microsurgical technique. Five transplantations were done for each combination. Postoperatively, donor heart beat was palpated everyday through the recipent's abdominal wall. Rejection was defined as complete cessation of donor heart beat. Result: The allogeneic heart grafts transplanted from PVG strain to ACI strain(PVG ACI) without DSBT were acutely rejected(mean survival 10.2 days). With pretransplant DSBT, the cardiac allografts in PVG ACI and LEW PVG combinations survived indefinitely(more than 100 days), those in ACI PVG combination survived 12 to 66 days(mean 31.8 days), those in PVG LEW survived 8 to 11 days(mean 10.0 days), and those in ACI LEW survived 7 to 9 days(mean 8.0 days). In brief, DSBT prior to heart transplantation was definitely effective in PVG ACI and LEW PVG combinations and moderately effective in ACI PVG combination, but not effective in PVG LEW and ACI LEW combinations. Conclusion: DSBT prior to heart transplantation showed variable effects, but might prolong cardiac allograft survival indefinitely in some donor recipient strain combinations. The mechanism of this effect should be further investigated.

• 대한임상전기생리학회지
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• 제8권1호
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• pp.37-42
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• 2010

Purpose : This study will recognize about the influences that stretching exercise with ultrasound and microwave application has on a knee joint position sense after induction to muscle fatigue. Methods : The object by each ten people divided at random thirty physical healthy adult men to constant group 1, group 2, group 3 to the objects. Treadmill exercised for induction to muscle fatigue, and let an exercise intensity decided on 85% of the maximum heart beat number with the goal heart beat number, and you exercise. Goal heart beat number measured as used heat rate monitor, and measured a oneself at the scale in order to recognize own physical state after end treadmill exercise to all objects to criteria to evaluate an ability shown in case of sports. Knee joint position sense used a N-K table, and experimenter did so as adaptation got passively arbitrary three angle done, and to order an original position. The object carried in person out one angle that experimenter designated, and measured repeatedly an error along him to this three times after being so. Rear before induction to muscle fatigue a position sense and measured after stretching exercise application, and played. Stretching exercise after induction applied stretching exercise, stretching exercise with ultrasound, stretching exercise with microwave, and applied to each group 1, group 2 and group 3 to muscle fatigue. Results : The result each group the difference which considers does not come out it was not but, improvement of the position sense is the possibility of knowing was from group 1, group 2 and group 3. Conclusion : These findings stretching exercise and stretching exercise with ultrasound and microwave after induct ion give help to a position sense elevation, and execute stretching exercise, and be effective against damage prevention by physical insecurity to muscle fatigue, and look.

• 한국통신학회논문지
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• 제40권4호
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• pp.731-739
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• 2015

부정맥 심전도 신호에는 전도장애 및 발생부위에 따라 다양한 비정상 모양을 띄는 특이심박들이 포함되어 있고, 이들 특이심박은 부정맥 등의 심장질환을 진단하는데 있어 매우 중요하다. 본 논문에서는 심실질환에 관련한 PVC 특이심박 검출 알고리즘을 제안한다. PVC 특이심박에서는 심전도 신호의 구성요소 가운데 QRS 군의 왜곡이 발생하는 특징이 있다. 따라서 QRS 군의 왜곡 정도에 따라 PVC 특이심박을 검출할 수 있다. 먼저 R-peak의 전위, 첨도, 주기를 사용하여 QRS 군의 왜곡을 정량화하고, 이들 값들의 평균과 표준편차를 이용하여 정상 심박과의 왜곡의 정도에 따라 PVC 특이심박을 검출한다. 제안한 알고리즘은 MIT-BIH 부정맥 데이터베이스 중 심실질환과 관계되는 AAMI-V class 타입의 특이심박을 평균 98% 이상을 검출할 수 있었다.

• Industrial Engineering and Management Systems
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• 제12권4호
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• pp.380-388
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• 2013

Large variation in electrocardiogram (ECG) waveforms continues to present challenges in defining R-wave locations in ECG signals. This research presents a procedure to extract the R-wave locations by forward-backward (FB) algorithm and classify the arrhythmic beat conditions by using RR intervals. The FB algorithm shows forward and backward searching rules from QRS onset and eliminates lower-amplitude signals near the baseline using a statistical process control concept. The proposed algorithm was trained the optimal parameters by using MIT-BIH arrhythmia database (MITDB), and it was verified by actual Holter ECG signals from a local hospital. The signals are classified into normal (N) and three arrhythmia beat types including premature ventricular contraction (PVC), ventricular flutter/fibrillation (VF), and second-degree heart block (BII) beat. This work produces 98.54% accuracy in the detection of R-wave location; 98.68% for N beats; 91.17% for PVC beats; and 87.2% for VF beats in the collected Holter ECG signals, and the results are better than what are reported in literature.

• 대한약리학회지
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• 제4권1호
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• pp.37-39
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• 1968

A method for presenting the heart rate of intact animals as a kymographic record is described. A transistorized impulse generator with a dry battery power supply is used to produce pulses. The pulses are integrated and make a pen motor drived. The ability of the instrument to follow a wide range of heart rate change is demonstrated. The instrument is especially usefull to observe an acute and transitory heart rate change. A method for changing the heart beat to sound and a method for counting the heart rate of intact animal and isolated preparations by employing post office counter were also described.

• Journal of Animal Science and Technology
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• 제63권3호
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• pp.651-661
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• 2021

This study aimed to investigate whether breed, sex, and age affected temperament differently (more or less neophobic) in mature horses during a novel object test. The study included Jeju crossbred (n = 12, age = 9.42 ± 4.57 y), Thoroughbred (n = 15, age = 10.73 ± 3.09 y), and Warmblood horses (n = 12, age = 13.08 ± 3.55 y) with the females (n = 22, age = 11.36 ± 4.24 y) and geldings (n = 17, age = 10.65 ± 3.66 y). Jeju crossbreds (Jeju horse × Thoroughbred) are valuable considering their popular usage in Korea, but limited studies have explored temperament of Jeju crossbred horses. A trained experimenter touched the left side of the neck with a white plastic bag (novel object). The test ended when the horse stopped escape response and heart rate (HR) dropped to baseline. Behavioral score and escape duration were measured as behavioral variables. Multiple variables related to HR and heart rate variability (HRV) were measured to reflect emotional state. These included basal HR (BHR), maximum HR (MHR), delay to reach maximum heart rate (Time to MHR), standard deviation of beat-to-beat intervals (SDNN), root mean square of successive differences (RMSSD), and ratio of low to high frequency components of a continuous series of heartbeats (LF/HF). Statistics revealed that Thoroughbreds had significantly higher behavioral scores, and lower RMSSD than Jeju crossbreds (p < 0.05), suggesting greater excitement and fear to the novel object in Thoroughbreds. None of the behavioral or cardiac parameters exhibited sex differences (p < 0.05). Age was negatively correlated with SDNN and RMSSD (p < 0.05), indicating that older horses felt more anxiety to the novelty than younger horses. Thoroughbreds and females had distinct correlations between behavioral and HRV variables in comparison with other groups (p < 0.05), implying that escape duration might be a good indicator of stress, especially in these two groups. These results are expected to improve equine welfare, safety and utility, by providing insights into the temperament of particular horse groups, to better match reactivity levels with specific functions.

• 센서학회지
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• 제20권2호
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• pp.118-123
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• 2011

Heart related diseases mainly caused by heavy work load and increasing stress in human daily life. Therefore, researches on mobile healthcare monitoring for daily life has been carried out. Notably, wearable healthcare monitoring system which has least restriction has been tried to provide an emergency alert of abnormal heart rate. In this study, we developed chair type unconstrained BCG measurement system which able to perform continuous heart status monitoring at the office and daily life in the unconstrained way. Furthermore, adaptive threshold is used to detect the heart rate from BCG signals. The HRV(heart rate variability) is calculated from heart rate interval. ECG signal measured using conventional method and BCG signal measured using unconstraint system are carried out simultaneously for the purpose of performance evaluation. From the comparison result, BCG signal shows a similar heart beat characteristic as ECG signal. This proves the possibility of practical implementation of unconstraint healthcare monitoring system. In addition, medical examination like valsalva maneuver is performed to observe the changes in HRV due to stress. By performing valsalva maneuver, heart is said to be placed under an artificial physical stress condition. Under this artificial physical stress condition, the time and frequency domain of HRV parameters are evaluated.

• 한국위성정보통신학회논문지
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• 제12권1호
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• pp.28-33
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• 2017

본 논문에서는 여러 곳에서 통용되고 있는 기존의 CW(continuous-wave) 레이더 송수신모델을 수정한 송수신모델을 제안한다. 최근에 심장박동과 호흡을 검출하기 위해 기존신호모델을 기반으로 CW(continuous-wave) 레이더에 대한연구가 진행 되고 있다. 그러나 이 통용되고 있는 수신모델은 인체 공학적으로 개념과 일치하지 않기 때문에 이모델을 근거로 실험을 할 경우 실제 개발되는 시스템 성능을 정확하게 예측할수 없다. 본 논문에서는 인체 공학상 개념과 일치하는 수정된 CW(continuous-wave) 레이더 송수신모델을 제안하고 가운시안 잡음rhk 다중경로 환경에서 심장박동 및 호흡검출에 대한 시뮬레이션을 수행하고 이를 기존수신모델과의 심장박동과 호흡검출에 대한 성능을 비교 분석한다.

• 혜화의학회지
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• 제14권2호
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• pp.55-70
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• 2005

In oriental medicine, Gamibangpungtongsungsan (KBTS) has been used as a therapeutic agent for the treatments of acute stage of cerebrovascular diseases and hypertension. In the present study, underlying mechanism on KBTS effects was investigated using spontaneously hypertensive rats (SHR) by determining related parameters such as blood pressure, heart-beat rates, and hormones and plasma constituents. The major finding are summarized as follows. 1. KBTS treatment at concentrations lower than $125\;{\mu}g/m{\ell}$ did not show any cytotoxicity on cultured human fibroblast cells. 2. KBTS treatment in SHR significantly decreased blood pressure and heart-beat rate compared with untreated control. 3. KBTS treatment in SHR decreased aldosterone levels in the blood compared with untreated control, but the difference was not statistically significant. 4. KBTS treatment in SHR significantly decreased dopamine, norepinephrine and epinephrine levels in the blood compared with untreated control. 5. KBTS treatment in SHR decreased plasma ion concentrations such as Na+, K+, Ca2+, Cl- compared with untreated control; decreases in Na+ and Cl- were statistically significant. 6. KBTS treatment in SHR significantly decreased TNF-$\alpha$, IL-6, and IL-10 levels in the blood compared with untreated control. Thus, the present data show evidence on anti-hypertension activity of KBTS in an experimental animal system, which can provide further insights into the development of anti-hypertension therapeutic agents.