• 제목/요약/키워드: Health research and development

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SWCNT 및 MWCNT의 기관내 점적주입 후 폐 계면활성제의 분석 (Analysis of Pulmonary Surfactant after Intratracheal Instillation of SWNCT and MWCNT)

  • 이병우;서정관;심일섭;엄익춘;김필제
    • 한국환경보건학회지
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    • 제43권4호
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    • pp.273-279
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    • 2017
  • Objectives: Carbon nanotubes (CNTs) are next-generation industrial nanoparticles which possess excellent mechanical strength along with good thermal conductivity and electric properties. Given these characteristics, carbon nanotubes are being widely applied in various fields, including research and development. However, concerns have been raised over hazardous properties due to their similar fiber shape to asbestos. Recent studies have shown that CNTs pose potential hazards which may cause fibrosis and/or lung inflammation similarly to asbestos. Methods: After intratracheal instillation of SWCNTs and MWCNTs to rats, pulmonary surfactant (PS) of the SWCNTs and MWCNTs was measured and analyzed using bronchoalveolar lavage fluid collected from the lung. After a single intratracheal instillation of SWCNTs and MWCNTs, phospholipid predominantly showed a significant increase compared to the control group, while proteins exhibited a significant increase both three days and one week after instillation. Results: As a result of surface tension, MWCNTs showed a significant decrease three days after treatment compared to the control group. In the case of the total cell number three days after instillation, MWCNTs revealed a temporarily significant increase when compared to the control group. For PMN number, when compared to the control group, SWCNTs displayed a significant increase throughout the observation period, while MWCNTs showed a significant increase three days and three months after treatment. Conclusions: After exposure to CNTs, the total cell number and PNT number, which indicate inflammatory response, were significantly increased. Therefore, this study suggests fiber-shaped CNTs may have a harmful effect on the lungs.

Assessment of Masks Used by Healthcare Workers: Development and Validation of a Mask Qualitative Assessment Tool (MQAT)

  • Gharibi, Vahid;Cousins, Rosanna;Mokarami, Hamidreza;Jahangiri, Mehdi;Keshavarz, Mohammad A.;Shirmohammadi-Bahadoran, Mohammad M.
    • Safety and Health at Work
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    • 제13권3호
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    • pp.364-371
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    • 2022
  • Background: Respiratory masks can provide healthcare workers with protection from biological hazards when they have good performance. There is a direct relationship between the visual specifications of a mask and its efficacy; thus, the aim of this study was to develop tools for qualitative assessment of the performance of masks used by healthcare workers. Methods: A mixed-methods design was used to develop a qualitative assessment tool for medical face masks (MFM) and particle filtering half masks (PFHM). The development of domains and items was undertaken using observation and interviews, the opinions of an expert panel, and a review of texts and international standards. The second phase evaluated the psychometric properties of tools. Finally, the validated Mask Qualitative Assessment Tools (MQAT) were used to assess six samples from 10 brands of the two types of masks. Results: MQAT-MFM and MQAT-PHFM shared 42 items across seven domains: "cleanliness," "design," "marking, labeling and packaging," "mask layers," "mask strap," "materials and construction," and "nose clip." MQAT-MFM included one additional item. MQAT-PHFM included another nine items associated with an eighth "Practical Performance" domain, and the valve version had another additional "Exhalation Valve" domain and six items. The evaluation indicated 80% compliance for MFM and 71% compliance for PFHM. "Marking, labeling and packaging" and "Layers" were associated with the least compliance in both types of masks and should be checked carefully for defining mask quality. Conclusion: MQAT can be used for immediate screening and initial assessment of MFM and PHFM through appearance, simple tools, and visual inspection.

지역사회역량이 건강에 미치는 영향에 대한 다수준 분석: 사회의 질 증진에 주는 함의 (A Multi-level Study of Contextual Effects of Community Capacity on Health Status among Seoul Residents: Focused on Social Quality)

  • 정민수;조병희
    • 보건교육건강증진학회지
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    • 제28권4호
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    • pp.1-14
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    • 2011
  • Objectives: The aim of the present study is to elucidate the relationship of community capacity to health in a metropolitan area in Korea. To do so, a multi-level model to verify the contextual effects of community capacity is presented. Methods: The study materials are the "The 4th Seoul Citizens Health Indicators Surveys" on 404 dong in Seoul. The community capacity indicators were developed in two strata: individual-level indicators with community identity domain; and community-level indicators with participation in community organizations, number of non-profit organizations, degree of organizing of community-based organizations, and volunteer activities. Results: Higher unhealthy probability occurs among those with lower community capacity at the community level, lower individual income, and lower community satisfaction at the individual level. It contributed to explaining self-rated health status and showed that there were contextual effects of the community going beyond the compositional effects of the individual. Conclusions: In the process of building community capacity, a community autonomously finds pending issues and solves related problems, and in so doing, raises the social quality and establishes the conditions for health promotion. Thus, the significance of neighborhood needs to be discovered and created in a new way through the development of community capacity.

한방산업의 정의와 분류에 대한 연구 (A research on the Korean medicine industry of define and classification)

  • 신현규
    • 한국한의학연구원논문집
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    • 제10권1호
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    • pp.97-105
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    • 2004
  • 1. To define 'Korean medicine industry' through study on existing medicine related industries, Korean medicine industry means all industrial activities related to Korean medicine. It covers material resources such as herbs and products made with herbs, medical instruments, Korean medical service and related information service based on Korean medicine theories. 2. According to Korea National Statistical Office standard industrial branch, Korean medicine industry was classified as a large branch. There were industries such as agriculture, food and beverage manufacture, publishing, copy of prints and record media, manufacture of compound and chemical products, medical service, manufacture of precise optical instruments, wholesale trade and product mediation, retail trade, restaurant, research and development, education service, health preservation service, entertainment, culture and sports industry related to the Korean medicine industry. 3. If we classify this according to the industry branch of English economists Clark, Colin Grant, herb cultivating industry will be classified as primary industry, manufacture of foot and beverage related to Korean medicine, secondary industry and wholesale and retail sales of herb, research and development, education, health preservation, social welfare, tertiary industries.

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Research trends over 10 years (2010-2021) in infant and toddler rearing behavior by family caregivers in South Korea: text network and topic modeling

  • In-Hye Song;Kyung-Ah Kang
    • Child Health Nursing Research
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    • 제29권3호
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    • pp.182-194
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    • 2023
  • Purpose: This study analyzed research trends in infant and toddler rearing behavior among family caregivers over a 10-year period (2010-2021). Methods: Text network analysis and topic modeling were employed on data collected from relevant papers, following the extraction and refinement of semantic morphemes. A semantic-centered network was constructed by extracting words from 2,613 English-language abstracts. Data analysis was performed using NetMiner 4.5.0. Results: Frequency analysis, degree centrality, and eigenvector centrality all revealed the terms ''scale," ''program," and ''education" among the top 10 keywords associated with infant and toddler rearing behaviors among family caregivers. The keywords extracted from the analysis were divided into two clusters through cohesion analysis. Additionally, they were classified into two topic groups using topic modeling: "program and evaluation" (64.37%) and "caregivers' role and competency in child development" (35.63%). Conclusion: The roles and competencies of family caregivers are essential for the development of infants and toddlers. Intervention programs and evaluations are necessary to improve rearing behaviors. Future research should determine the role of nurses in supporting family caregivers. Additionally, it should facilitate the development of nursing strategies and intervention programs to promote positive rearing practices.

Damage assessment of structures - an US air force office of scientific research structural mechanics perspective

  • Giurgiutiu, Victor
    • Smart Structures and Systems
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    • 제6권2호
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    • pp.135-146
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    • 2010
  • This paper presents the perspective of the Structural Mechanics program of the Air Force Office of Scientific Research (AFOSR) on the damage assessment of structures for the period 2006-2009 when the author was serving as Program Manager at AFOSR. It is found that damage assessment of structures plays a very important role in assuring the safety and operational readiness of US Air Force fleet. The current fleet has many aging aircraft, which poses a considerable challenge for the operators and maintainers. The nondestructive evaluation technology is rather mature and able to detect damage with considerable reliability during the periodic maintenance inspections. The emerging structural health monitoring methodology has great potential, because it will use on-board damage detection sensors and systems, will be able to offer on-demand structural health bulletins. Considerable fundamental and applied research is still needed to enable the development, implementation, and dissemination of structural health monitoring technology.

화학물질 노출정보 제공을 위한 GC-MS 분석자동화 프로그램 개발 (Development of a GC-MS Automatic Analysis Program to Provide Information on Exposure to Chemical Substances)

  • 박승현;박해동;장미연;노지원;조현민
    • 한국산업보건학회지
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    • 제31권1호
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    • pp.1-12
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    • 2021
  • Objective: The purpose of this study was to contribute to the prevention of occupational diseases through the development of an automatic analysis program for evaluating workers' exposure to hazardous chemical substances. Methods: The authors selected chemical substances that caused occupational disease in Korea and chemical substances that are frequently used in industrial sites as target substances for a GC-MS automatic analysis program. The target substances are organic compounds which can be measured by a passive sampler. The automatic analysis program was studied using various raw data obtained from GC-MS analysis for the target substances. Results: A total of 48 organic compounds that can be measured with a passive sampler were selected as target substances for the GC-MS automatic analysis program. The selected compounds included substances that caused occupational disease, substances related to C1 and D1 in special health examinations, and substances for which work environment measurements have been frequently conducted. The GC-MS automatic analysis program was developed by combining information mainly on retention time and mass spectrum. The GC-MS automatic analysis program is designed to analyze unknown samples by comparing the mass spectrum and retention time of the samples to those of reference materials. To evaluate the stability of the program, samples at about the 30-50% level of OELs were prepared and analyzed with the GC-MS automatic analysis program, resulting in stable results for all 48 organic compounds. Conclusion: An automatic analysis program for a total of 48 organic compounds was developed using a GC-MS system that can analyze organic compounds. Unknown samples that contain the 48 organic compounds can be automatically analyzed by the developed program. It is anticipated that it can contribute to the prevention of occupational diseases through an GC-MS automatic analysis program that can quickly provide workers with information on exposure to chemical substances.

물리치료 기술 개발 방향 정립을 위한 세부 연구 분야 우선순위 도출 (Derived of agenda priority for research and development with physical therapy technology)

  • 김형근;하현근;배영현
    • 대한물리치료과학회지
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    • 제29권1호
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    • pp.15-29
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    • 2022
  • Background: The purpose of this study was to suggest agenda priorities for research and development with physical therapy technology. Design: Cross-sectional study. Methods: A survey was consecutively done to 62 experts working in physical therapy research areas to investigate the priority of the categories. Paired T-tests and Importance-Performance Analysis using SPSS 21.0 package were conducted to find the differences between importance and satisfaction of the categories and the order of priority. Results: In results, it was developed that the research and development with physical therapy technology were divided with 18 categories. And the importance were significantly higher than satisfaction in 18 categories. Specifically, categories about assistive technology and robot rehabilitation were found to be on the high importance and lower performance quadrant. Conclusion: In sum, this study was meaningful in finding usage categories of research and development with physical therapy technology and investigating Importance-Performance differences for deriving research and development with physical therapy technology.

OECD 병원 성과 프로젝트의 동향과 국내 시사점 (Trend and Implication of OECD Hospital Performance Project)

  • 박춘선;최효정;황수희;임지혜;김경훈;김선민
    • 한국의료질향상학회지
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    • 제22권1호
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    • pp.11-26
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    • 2016
  • The Organization for Economic Cooperation and Development, which has continuously evaluated the performance of healthcare systems, has recently invested much effort into hospital performance measurement. The purpose of this paper is to introduce the hospital performance measurement programs operated by international organizations or at the national level based on the OECD's hospital performance project. Health Insurance Review & Assessment service (HIRA)'s quality assessment was analyzed based on the analytical framework of the OECD's hospital performance project. The hospital performance measurement programs of WHO, Canada, Australia, United States and United Kingdom are briefly explored, in view of the conceptual framework, key performance dimensions and indicators that are currently in use. The OECD suggested seven key dimensions of hospital performance: timeliness, efficiency, continuity, effectiveness and appropriateness, staff orientation, patient orientation and safety. The analysis of the quality assessment program of HIRA, which operates 36 diseases and procedures and 347 indicators, shows that the numbers of indicators are relatively small in the areas of safety, patient centeredness and efficiency. Continuity of care and staff orientation are not fully developed also, but the situations are similar in other countries. In conclusion, hospital performance measurement using stable and comprehensive data should be developed to improve overall system performance, and discussions on a conceptual framework that can lay out directions and key performance domains need to take into place.