• Title/Summary/Keyword: Healing Function

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A study on Crack Healing of Various Glassy Polymers (part I) -theoretical modeling- (유리질 중합체의 균열 Healing에 관한 연구 (제1보) -이론 모델링-)

  • Lee, Ouk-Sub
    • Journal of the Korean Society for Precision Engineering
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    • v.3 no.1
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    • pp.40-49
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    • 1986
  • Crack, craze and void are common defects which may be found in the bulk of polymeric materials such as either themoplastics or thermosets. The healing phenomena, autohesion, of these defects are known to be a intrinsic material property of various polymeric materials. However, only a few experimental and theoretical investigations on crack, void and craze healing phenomena for various polymeric materials have been reported up to date [1, 2, 3]. This may be partly due to the complications of healing processes and lacking of appropriate theoretical developments. Recently, some investigators have been urged to study the healing phenomena of various polymenic materials since the significance of the use of polymer based alloys or composites has been raised in terms of specific strength and energy saving. In the earlier published reports [1, 2, 3, 4], the crack and void healing velocity, healing toughness and some other healing mechanical and physical properties were measured experimentally and compared with predicted values by utilizing a simple model such as the reptation model under some resonable assumptions. It seems, however, that the general acceptance of the proposed modeling analyses is yet open question. The crack healing processes seem to be complicate and highly dependent on the state of virgin material in terms of mechanical and physical properties. Furthermore, it is also strongly dependent on the histories of crack, craze and void development including fracture suface morphology, the shape of void and the degree of disentanglement of fibril in the craze. The rate of crack healing may be a function of environmental factors such as healing temperature, time and pressure which gives different contact configurations between two separated surfaces. It seems to be reasonable to assume that the crack healing processes may be divided in several distinguished steps like stress relaxation with molecular chain arrangement, surface contact (wetting), inter- diffusion process and com;oete healing (to obtain the original strength). In this context, it is likely that we no longer have to accept the limitation of cumulative damage theories and fatigue life if it is probable to remove the defects such as crack, craze and void and to restore the original strength of polymers or polymer based compowites by suitable choice of healing histories and methods. In this paper, we wish to present a very simple and intuitive theoretical model for the prediction of healed fracture toughness of cracked or defective polymeric components. The central idea of this investigation, thus, may be the modeling of behavior of chain molecules under healing conditions including the effects of chain scission on the healing processes. The validity of this proposed model will be studied by making comparisons between theoretically predicted values and experimentally determined results in near future and will be reported elsewhere.

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The Plan Method for Residents in Townhouse Focused on the Communicational Viewpoint with Nature (자연과의 소통적 관점에서 본 타운하우스에서 거주자 치유를 위한 계획방법)

  • Park, In-Ji;Seo, Ji-Eun
    • Korean Institute of Interior Design Journal
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    • v.26 no.6
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    • pp.13-23
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    • 2017
  • The purpose of this study is to analyze the expression method according to the planning of townhouse and the healing method that affects residents for communicating with natural environment, in order to propose resident-focused communication with nature for healing. The results are as follows. First, the expression of nature elements can be divided into 'direct' and 'indirect' and healing effects through nature can be divided into 'body' and 'psychology'. The healing method of residents through nature was classified into physical and psychological healing through openness, familiarity, comfort, and stability. Second, as an expression method according to townhouse planning, the arrangement plan induced active communication with nature through the arrangement according to topography and a common garden. In terms of construction plan, a bigger window or door than that of other residential spaces was installed on a wall, ceiling or opening to directly bring the nature of outside visually for more communication. Third, with regard to healing methods of townhouse, 'openness' which reduces depression and increases self-esteem, expands the view of residents. 'Familiarity', the healing method that can relieve the fatigue of eyes and bring psychological warmth and comfort, makes us feel familiar through the pattern and texture of woods and stones that are natural materials. 'Comfort' which heals residents by creating an outside space and bringing the nature elements through a huge window can provide psychological healing such as eased tension in daily life as well as physical healing such as vitamin D synthesis and the recovery of physiological function. Also, 'Stability' gives a comfortable feeling by applying the colors of finishing materials inside or seeing the colors of surrounding nature as it is through big windows. Finally, in order to support the results of this study more objectively, a follow-up study conducting a survey on the residents of townhouse is needed.

Effect of Pahyeolsandong-tang (Poxiesanteng-tang) in Tibia Fracture-induced Mice (경골 파혈산동탕(破血散疼湯)이 골절 생쥐의 골 유합에 미치는 영향)

  • Shin, Woo-Suk;Parichuk, Kira;Cha, Yun-Yeop
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.4
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    • pp.1-16
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    • 2020
  • Objectives The main purpose of this study was to evaluate the bone healing effect of Pahyeolsandong-tang (PHT)(Poxiesanteng-tang) extract in tibia fracture-induced mice. Methods PHT was extracted using a solution of 35% ethanol in 60℃ for 8 hours. Mice were randomly divided into 4 groups (normal, control, PHT 50 and PHT 100). Mice of experimental groups were medicated with PHT 50 or 100 mg/kg for 7 to 21 days. To clarify the effect of bone fracture healing, relative messenger RNA (mRNA) expressions of osteocalcin (OCN), runt-related transcription factor 2 (Runx2), osterix (OSX), Sox9, collagen type II alpha 1 chain (Col2a1), receptor activator of nuclear factor kappa-B ligand (RANKL), osteoprotegerin (OPG) were examined. Results In in vitro experiment, relative mRNA expression of OCN, Runx2, Col2a1 was significantly increased in PHT treated group to compare with control differentiation group. In in vivo experiment, relative mRNA expression of OCN, Runx2, OSX, Sox9, Col2a1, RANKL, OPG was significantly increased in PHT treated group. Conclusions This study showed that PHT accelerates bone fracture healing through the activation of osteoclasts and osteoblasts. It was showed that PHT significantly promotes osteoblasts differentiation by osteoblast differentiation markers such as OCN, Runx2, Col1a2. Also it was investigated that PHT had stimulatory effect on osteoblasts function through enhancing OCN, Runx2, OSX, Sox9, Col2a1 and, osteoclasts function through enhancing RANKL and OPG markers. PHT effectively promotes bone fracture healing process through activation of osteoblasts and osteoclasts.

The Structure of Healing in the Functor and Semantic Arguments Appearing in the Poem "Bellflower Flower" by Cho Ji-Hoon (조지훈의 시 「도라지꽃」에 나타나는 함수자와 의미론적 논항의 치유의 구조)

  • Park, In-kwa
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.1
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    • pp.275-278
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    • 2018
  • This study examines how poem and poetic ego of Cho Ji-Hoon form synapses. It is to clarify the synaptic structure of the healing, the contact point between the literary mechanism and the mechanism of the ego. Therefore, it aims to encode the active therapy by substituting the structure into the literary therapy program. Cho Ji-Hoon's poem "Bellflower Flower" is a mesh of poem, and a mesh of semantic arguments is set up for the 'Bellflower Flower' of functor. At this time, the longing that attracts depression to the net of the semantic argument is caught. This exists as a function of healing. If we embody a literary therapy program that utilizes the synaptic structure of this healing, it will be able to experience the function of literary therapy improved than before.

630 nm-OLED Accelerates Wound Healing in Mice Via Regulation of Cytokine Release and Genes Expression of Growth Factors

  • Mo, SangJoon;Chung, Phil-Sang;Ahn, Jin Chul
    • Current Optics and Photonics
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    • v.3 no.6
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    • pp.485-495
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    • 2019
  • Photobiomodulation (PBM) using organic light emitting diodes (OLEDs) surface light sources have recently been claimed to be the next generation of PBM light sources. However, the differences between light emitting diodes (LEDs) and OLED mechanisms in vitro and in vivo have not been well studied. In vivo mouse models were used to investigate the effects of OLED irradiation on cellular function and cutaneous wound healing compared to LED irradiation. Mice in the LED- and OLED-irradiated groups were subjected to irradiation with 6 J/㎠ LED and OLED (630 nm), respectively, for 14 days after wounding, and some mice were sacrificed for the experiments on days 3, 7, 10, and 14. To evaluate wound healing, we performed hematoxylin-eosin and Masson's trichrome staining and quantified collagen density by computerized image analysis. The results showed that the size of the wound, collagen density, neo-epidermis thickness, number of new blood vessels, and number of fibroblasts and neutrophils was significantly influenced by LED and OLED irradiation. The tissue levels of interleukin (IL)-β, IL-6 and tumor necrosis factor (TNF)-α were investigated by immunohistochemical staining. LED and OLED irradiation resulted in a significant increase in the tissue IL-β and IL-6 levels at the early stage of wound healing (P < 0.01), and a decrease in the tissue TNF-α level at all stages of wound healing (P < 0.05), compared to the no-treatment group. The expression levels of the genes encoding vascular endothelial growth factor and transforming growth factor-beta 1 were significantly increased in LED and OLED-irradiated wound tissue at the early stage of wound healing (P < 0.01) compared to the no-treatment group. Thus, OLED as well as LED irradiation accelerated wound healing by modulating the synthesis of anti-inflammatory cytokines and the expression levels of genes encoding growth factors, promoting collagen regeneration and reducing scarring. In conclusion, this suggests the possibility of OLED as a new light source to overcome the limitations of existing PBMs.

Adventure filming game for people in need of healing (힐링이 필요한 사람들을 위한 3D 어드벤처 촬영 게임)

  • Shin, Soyeon;Joo, Heesun;Choi, Yeonho;Choi, Jongin;Park, Su-E
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.05a
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    • pp.133-136
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    • 2022
  • As the number of stress-related diseases increases due to the prolonged Corona 19, Corona Blue is attracting attention. This social background causes negative emotions due to frustration at work, changes in existing life rhythms, and blockade of economic sources, and makes us understand our era as an era in need of healing. Therefore, the purpose of this study is to propose a 3D-based adventure filming game that adventures a fantastic space and stores memories and experiences through photos. For this, important elements of healing were explored through literature study, and based on this, a game using 3ds Max and Unity was implemented. As a result of the study, the game was implemented with a filming function that contains visual elements for cute and warm healing, an emotionally approaching story, and the meaning of space. This study provides a game that can provide non-face-to-face healing to users and presents effective and important healing factors to service providers.

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The Comparison of Vestibular Function and Dynamic Balance Skills between Normal and Hearing-Impaired Children (정상아동과 청각장애아동의 전정기능과 동적균형수행력 비교)

  • Lee Seung-Min;Kim Jin-Sang;Choi Jin-ho
    • The Journal of Korean Physical Therapy
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    • v.12 no.1
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    • pp.33-40
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    • 2000
  • This study was carried out to compare the relation between vestibular function and balance skills in normal with heating-impaired children. The subjects were 20 normal children (8-10 years) and 20 hearing-impaired children (8-10 years). The SCPNT was used to assess vestibular function, then, functional reach test and backward walking test were usee to compare dynamic balance skills of normal and hearing-impaired children according to existence of visual input. The results were as follows : 1. In SCPNT, normal and hearing-impaired children showed statistical significance in all left-sided and right-sided rotations(p<.01), and the vestibular function responses of healing-impaired children were normal $20\%$, abnormal $45\%$, absent $35\%$. 2, To compare dynamic balance skills between normal and healing-impaired according to eye open and eye close, functional reach test did not show statistical significance in eye open situation(p>.05), but showed statistical significance in eye close situation(p<.05). 3. Backward walking test showed statistical significance in eye open and eye close situation(p<.01).

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A Study on the Planning of Entry Space in General Hospital - Focused on the corridor and the waiting space - (종합병원 진입부 공간계획에 관한 연구 - 복도 및 대기공간을 중심으로 -)

  • Youn Woo-Young;Chai Choul-Gyun
    • Korean Institute of Interior Design Journal
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    • v.15 no.1 s.54
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    • pp.106-112
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    • 2006
  • Buildings undergo changes by various factors according as pass at time. Due to that social requests and issues form one common sense of value and this would influence the architect's design intention. In fact, the form and function of buildings have coped with transition of the common sense of value by each times. Hospital architecture is also changed in function, scale and technology since, Kwanghyewon which was the first western style hospital in Korea was established in 1885. It is changing that the social needs for hospital which was a basic function of healing to laying emphasis on the function of precaution. According to this, the change of hospital spaces means that it can promote healing environment which is expanded from the modern concept of isolation, accommodation and urban sanitation. These changed concepts were adopted limited areas in hospitals at first however, nowadays they are expanding to other areas. So, this is caused to make the image of the hospital. From this point of view, Entry space is an example to show the changes. This study is intended to determine the overall space structure of entry area and to classify and analyze the difference.

Thermal Stability of Grubbs' Catalyst and Its Reactivity with Self-healing Agents (Grubbs' Catalyst의 열안정성 및 자가치료제와의 반응성 평가)

  • Yoon, Sung Ho;Shi, Ya Long;Feng, Jun;Jang, Se Yong
    • Composites Research
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    • v.28 no.6
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    • pp.395-401
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    • 2015
  • This study investigated the thermal stability of Grubbs' catalyst and its reactivity with self-healing agents for self-healing damage repair. Four types of Grubbs' catalyst supplied by manufacturers were considered and each catalyst was tested in as-received and grinded conditions. Four types of self-healing agents were prepared by varying the mixing ratio of dicyclopentadiene (DCPD) and 5-ethylidene-2-norbonene (ENB). Heat flows as a function of temperature were measured through a differential scanning calorimetry (DSC) to determine the thermal stability of catalysts. Reaction heats of self-healing agents with the catalyst were measured to evaluate the reactivity of the catalyst. For this evaluation, Fluka Chemika Grubbs' catalyst was used based on the maximum temperature and the time to reach the maximum temperature. According to the results, catalysts had different shapes depending on the manufacturer and the results showed that the smaller the size of the catalyst the higher the reactivity with self-healing agents. As the ENB ratio in self-healing agents increased, the maximum temperature increased, and the time to reach the maximum temperature decreased. As the amount of the catalyst increased, the maximum temperature increased, and the time to reach the maximum temperature decreased. Considering the thermal stability of the catalyst and its reactivity with the self-healing agent, combination of 0.5 wt% catalyst and the D3E1 self-healing agent was optimal for self-healing damage repair. Finally, as the thermal decomposition may occur depending on the environmental temperature, the catalyst must not be exposed to temperature higher than that is necessary to maintain the thermal stability of the catalyst.

The Study on Clinical Application of Osteopathy to Oriental Medicine (Osteopathy 의 한의학적 임상활용 방안에 관한 소고)

  • Hong, Seo-Young;Lim, Hyung-Ho
    • The Journal of Korea CHUNA Manual Medicine
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    • v.3 no.1
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    • pp.85-96
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    • 2002
  • Objectives : The purpose of this study is to get knowledge about osteopathy and to applicate the osteopathy to oriental medicine. Methods: We investigated several books and literatures on osteopathy related sites explored by internet to know the general theories and present conditions of osteopathy in Korea and other countries. Results & Conclusion : 1. The principles of osteopathy are as follows. First, the human being is a dynamic unit of function. Second, the body possesses self regulating mechanisms which are self healing in nature. Third, structure and function are reciprocally interrelated. Fourth, the body rational therapy is based upon knowledge and use of the above three principles. 2. Doctors of osteopathy evaluate the musculoskeletal system to identify structural problems and to support the body's natural tendency toward health and self healing. 3. We can applicate the osteopathy to oriental clinical medicine based on interpreting the principles of osteopathy.

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