• Fisheries and Aquatic Sciences
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• v.18 no.3
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• pp.273-281
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• 2015

The follistatin (FST) gene encodes a monomeric glycoprotein that plays a role in binding and inhibiting the functions of members of the transforming growth factor (TGF)-${\beta}$ superfamily. Thus, FST facilitates a wide variety of functions, ranging from muscle growth, to inflammation and immunity. In this study, we sought to characterize an FST counterpart, RbFST, which was identified from rock bream Oplegnathus fasciatus. The RbFST cDNA sequence (2,419 bp) contains a 933-bp open reading frame (ORF) that encodes a putative amino acid sequence for RbFST (35 kDa). The putative amino acid sequence contains a Kazal-type serine protease inhibitor domain (51-98 residues) and an EF-hand, calcium-binding domain (191-226 residues). Additionally, this sequence shares a high identity (98.7%) with the Siniperca chuatsi FST sequence, with which it also has the closest evolutionary relationship according to a phylogenetic study. Omnipresent distribution of RbFST transcripts were detected in the gill, liver, spleen, head kidney, kidney, skin, muscle, heart, brain, and intestine of healthy animals, with significantly higher expression levels in the heart, followed by the liver tissue. Under pathogenic stress caused by two bacterial pathogens, Streptococcus iniae and Edwardsiella tarda, RbFST transcription was found to be significantly up-regulated. Altogether, our findings suggest the putative role of RbFST in immune related responses against pathogenic infections, further prefiguring its significance in rock bream physiology.

• Radiation Oncology Journal
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• v.1 no.1
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• pp.25-28
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• 1983

Anterior and posterior parallel opposed field technique covering entire neck is desirable for elimination of junctional problems in treating upper neck with bilateral parallel opposed fields and lower neck with anterior one field. For good dose distribution in neck, dose in build-up region should be high for anterior field and should be low for posterior field. And so, with 10 MV X-ray, lead absorber was used for anterior field only. The adequate thickness of lead absorber, absorber-skin separation, width of central cord block for posterior field and anterior & posterior field weight were studied using film dosimery. The results are as follows. 1. As the thickness of the lead absorber increased the dose in build-up region increased. 2. As the absorber-skin separation decreased the dose in build-up region increased. 3. The adequate thickness of lead absorber was around 5.6mm. 4. The adequate absorber-skin separation was around 5cm. 5. The adequate posterior cord block width was 3cm. 6. 4:1 weighting for anterior and posterior field was adequate. And so with this technique, adequate dose distribution could be made as well as elimination junction problems.

• The Journal of Advanced Prosthodontics
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• v.8 no.3
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• pp.229-234
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• 2016

PURPOSE. The purpose of this study was to investigate the demographic patterns of maxillofacial prosthetic treatment to identify the characteristics and geographic distribution of patients with maxillofacial prosthetics in the capital region of Korea. MATERIALS AND METHODS. This retrospective analytical multicenter study was performed by chart reviews. This study included patients who visited the department of prosthodontics at four university dental hospitals for maxillofacial prosthetic rehabilitation. Patients with facial and congenital defects or with insufficient medical data were excluded. The patients were classified into three categories based on the location of the defect. Patients' sex, age, and residential area were analyzed. Pearson's chi-square test with a significance level of 0.05 was used to analyze the variables. RESULTS. Among 540 patients with maxillofacial prosthetics, there were 284 (52.59%) male patients and 256 (47.41%) female patients. The number of the patients varied greatly by hospital. Most patients were older than 70, and the most common defect was a hard palate defect. Chi-square analysis did not identify any significant differences in sex, age, and distance to hospital for any defect group (P>.05). CONCLUSION. The results of this study indicated that there was imbalance in the distribution of patients with maxillofacial prosthetic among the hospitals in the capital region of Korea. Considerations on specialists and insurance policies for the improvement of maxillofacial prosthetics in Korea are required.

• Aerospace Engineering and Technology
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• v.6 no.1
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• pp.128-135
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• 2007

Combustion characteristics of full-scale gas generators were studied experimentally by changing the injector number installed at the injector head. Three full-scale gas generators were utilized; they have same total mass flow rate but mass flow rates per injector are different. Thirteen, nineteen and thirty seven injectors, which have internal-mixing and double-swirl characteristics, are distributed in injector heads, respectively. The results showed that pressure fluctuations in the gas generators with 13 and 19 injectors didn't occur around longitudinal resonant frequency, however longitudinal-mode pressure fluctuation appeared slightly in the gas generator with 37 injectors. As the number of injectors increased, deviations of temperature distribution in the combustion chamber decreased gradually, but the damage of injector LOx posts became a little severe.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.17 no.7 s.110
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• pp.684-693
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• 2006

In this paper, the SA (Specific Absorption) distribution in a human head, exposed to wideband pulse EMF, has been analyzed by taking into account the dispersion characteristics of biological tissues. The dispersive properties of biological tissues are characterized by the 4th Cole-Cole model. Currently, there is no dispersive FDTD algorithm to implement the 4th Cole-Cole model accurately. Thus, in this paper the FDTD methods with the dispersive algorithm for the 1st-order Cole-Cole model and the 3rd-order Debye model were used for SA analysis. The validity of each model has been investigated first, and then the effects of dispersion on SA distribution have been studied.

• Journal of the Korean Geotechnical Society
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• v.27 no.2
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• pp.5-15
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• 2011

This research performed the laboratory model tests for Top-Base Foundation developed in Japan and Floating Top-Base Foundation developed in Korea on the typical clayey soft soils, namely, clay, clayey silt and clayey sand. The performances of the two types of top-base foundation were compared with each other and evaluated by measuring load-settlement, heaving of foundation side, ground stress distribution in this model tests. The change of settlement caused by the increase of top base width was also analyzed. As a result of the model tests, Floating Top-Base Foundation showed better performance in bearing capacity improvement, settlement decrease, stress dispersion effect and lateral confinement force. And settlement caused by the increase of top base width converged to a regular value from $5{\times}5$ layout of the width.

• Journal of Korean Foot and Ankle Society
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• v.12 no.1
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• pp.41-46
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• 2008

Purpose: This study was designed to evaluate characteristics of foot pressure distribution with or without partial prosthetic foot in transmetatarsal amputee. Materials and Methods: The subjects were 9 transmetatarsal amputees. Foot pressures were measured at hallux, the $1^{st}-5^{th}$ metatarsal head (MTH), mid-foot, condyle area by F-scan system in amputated or contralateral foot during active walking. Results: In amputated foot, mean peak pressure was greatest in midfoot without prosthetic foot but it was greatest in hindfoot with prosthetic foot. In unaffected foot, although mean peak pressure was higher in hallux, and $1-5^{th}$ MTH compared to amputated foot, it was greatest in hind foot both with and without prosthetic foot. However, in unaffected foot, mean peak pressure significantly decreased in hallux and $5^{th}$ MTH after wearing the prosthetic foot. There was a significant difference in mean peak pressure in hallux and $5^{th}$ MTH between amputated and unaffected foot after wearing prosthetic foot. However, other region had no significant difference with or without prosthetic foot between feet. Conclusions: The use of partial prosthetic foot tends to shift weight bearing from the heel area to forefoot and could significantly reduce hind foot peak pressure and redistributed to peak pressure. The partial prosthetic foot can also offer the peak pressure to reduction both amputated foot and unaffected foot and help to toe off during walking.

• Proceedings of the KSAR Conference
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• 2003.06a
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• pp.96-96
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• 2003

Nek2 (NIMA-related protein) is a mammalian cell cycle-regulated kinase that involves in chromosome condensation and centrosome regulation and NuMA (nuclear mitotic apparatus protein) is involved in spindle assembly during a cell cycle. The cellular distribution and organization of the centrosomal components is completely unknown during fertilization and embryonic development. We examined distribution of two well-known centrosomal proteins, Nek2 and NuMA in mouse gametes and embryos to get an insight in the reorganization of centrosomal proteins during germ cell development and early fertilization. Spermatogenic cells, gametes, and embryos were analyzed with anti-Nek2 or -NuMA antibodies by immunological assay, RT-PCR, and overexpression through gene transfection. Mitotically or meiotically active spermatogenic cells were intensively stained with these antibodies in both centrosomes and cytoplasm, whereas the oocytes showed different staining patterns depending on the meiotic stages. During maturation, GV, GVBD, and MI stage were clearly stained with NuMA antibody in the nucleus or cytoplasm at MII. Also, Nek2 was detectable in cytoplasm as scattered spots or chromosome associated at MII. In early developmental embryo, NuMA was detected in nucleus of each blastomere, while Nek2 was detected in cytoplasm. In contrast to previously reported results, Nek2 and NuMA were detected in both decondensing head, and the centriole of demembranated and decondensed sperm or whole body of trypsin-treated sperm for Nek2. During meiotic progress in oocytes, transcripts levels were the highest in MI stage and then downregulated in MII. Also, it shows dramatically change in early developmental embryos, firstly, it was increased until 4 cell stage and reduced in 8 cell stage, and finally, transcript levels were upregulated until blastoscyst. This finding suggests that cnetrosomal component may play an important role in reorganizing of functional centrosome during fertilization process and subsequent development.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.05a
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• pp.71-76
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• 2008

In this study, side force, drag, and the yawing moment were measured based on the angle of attack by using two models of different nose shapes with slender bodies, which were general shapes in the subsonic area. As a result, the side force and yawing moment were the highest at a specific angle of attack. The boundary between asymmetrical normal state and asymmetrical abnormal state were able to be seen. As a result of analyzing the side force, drag, and yawing moment by time, reliability varied depending on the shape of the head at the same angle of attack. The results of measuring pressure distribution from the surface of the slender body at each angle of attack were as follows: as the angle of attack gets higher, the distribution of surface pressure was asymmetrical.

• Journal of the Korean Society for Precision Engineering
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• v.24 no.7 s.196
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• pp.120-125
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• 2007

Analysis of elders' behavioral characteristic during showering provides important fundamental data when developing an automatic showering system. We recorded showering behavior of 37 elders' at the front, back, left and right view using four CCTV cameras. The photographic data were analyzed by counting the frequencies of body scrub and identifying zones where hands could reach. And we measured their body sizes, and conducted questionnaire of showering for 302 peoples. Analysis was done according to the analysis criteria established. The human body was divided into 14 zones from a body, and the numbers of body scrub for each zone were counted. The average total numbers of body scrub were 170.8 excluding the head, the face and the neck. The average numbers of body scrub with right hand were 70.2, left hand were 88.2, and both hands were 81.8. The percentages of body scrub frequencies were 16.3% (breast), 12.2%(crotch), 8.8% (abdomen), 7.5% (waist), 8.8% (shoulder), 7% (hips), 0.4% (back), 15.2% (arm), and 23.9% (leg). Elders scrubbed the breast, crotch and abdomen more frequently than the back and hips. According to the video analysis and questionnaire results, the distribution of shower heads (or nozzles) at the front side should be arranged at the ratio of 40% of the trunk(breast, shoulders, abdomen), 20% of the thighs, the calves, and the crotch, respectively. The distribution of shower heads (or nozzles) of the back side were arranged at the ratio of 20% of the waist and the arms, 20% of the back, the thighs, the calves, and the hip, respectively.