• Journal of Trauma and Injury
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• 제34권3호
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• pp.203-207
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• 2021

Penetrating brain injury caused by a nail gun is an uncommon clinical scenario reported in the literature. A 36-year-old male presented with a nail that had penetrated through the occipital bone. He was alert and neurologically intact except for visual disturbance. Computed tomography (CT) of the brain showed the nail lodged at the occipital lobe and the parietal lobe, with minimal intracerebral hemorrhage. The nail was placed in the occipital lobe close to the superior sagittal sinus. We removed the nail with craniotomy since the entrance of the nail was close to the superior sagittal sinus. There were no newly developed neurological deficits postoperatively. Immediate postoperative CT showed no newly developed lesions. The patient recovered well without any significant complications. Two weeks postoperatively, magnetic resonance imaging showed no remarkable lesions. The visual disturbance was followed up at the outpatient department. To summarize, we report a rare case of penetrating head injury by a nail gun and discuss relevant aspects of the clinical management.

• Nuclear Engineering and Technology
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• 제54권5호
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• pp.1769-1780
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• 2022

A new method of dose calculation algorithm, called GPU-accelerated Monte Carlo and collapsed cone Convolution (GMCC) was developed to improve the calculation speed of BNCT treatment planning system. The GPU-accelerated Monte Carlo routine in GMCC is used to simulate the neutron transport over whole energy range and the Collapsed Cone Convolution method is to calculate the gamma dose. Other dose components due to alpha particles and protons, are calculated using the calculated neutron flux and reaction data. The mathematical principle and the algorithm architecture are introduced. The accuracy and performance of the GMCC were verified by comparing with the FLUKA results. A water phantom and a head CT voxel model were simulated. The neutron flux and the absorbed dose obtained by the GMCC were consistent well with the FLUKA results. In the case of head CT voxel model, the mean absolute percentage error for the neutron flux and the absorbed dose were 3.98% and 3.91%, respectively. The calculation speed of the absorbed dose by the GMCC was 56 times faster than the FLUKA code. It was verified that the GMCC could be a good candidate tool instead of the Monte Carlo method in the BNCT dose calculations.

• 대한치과교정학회지
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• 제35권4호
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• pp.251-261
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• 2005

두부방사선규격사진은 작은 크기의 방사선원에서 방사상으로 방사선이 퍼져나감으로써 피사체의 확대와 왜곡이 불가피하다는 단점이 있다. 본 연구는 두 장의 방사선사진을 서로 직각으로 촬영한 후 방사선의 기하학적 성질을 이용하여 좌우 우각부간 폭경을 계산할 경우 실제 폭경의 산출이 가능한지 알아보고자 시행되었다. 성인 40명을 연구대상으로 하여 두부자세재현기를 이용하여 측모두부방사선사진과 정모두부방사선사진을 서로 직각으로 촬영한 후 측모사진과 정모사진에서의 확대율을 이용하여 실제 우각부 폭경을 산출한 다음 계측치 및 산출치를 3차원 CT영상에서의 계측치와 각각 비교 분석하였다. 연구결과 정모두부방사선사진에서 우각부 폭경은 작게는 7.92mm 크게는 11.31mm까지. 평균 9.10mm의 확대를 보였다. 측모 및 정모두부방사선사진을 이용하여 얻은 우각부 폭경 보정치를 3차원 CT영상에서 얻은 기준치와 비교한 결과 평균 0.14mm의 작은 오차를 보였으며 통계적으로 유의한 차이를 보이지 않아 측모 및 정모두부방사선사진 촬영 시 두부자세재현기를 이용하여 서로 직각으로 촬영할 경우 실제 우각부 폭경을 계산을 통해 산출할 수 있음을 보여주었다. 한편 이부편위량과 보정오차는 통계적으로 유의한 상관성을 보이지 않아 안면비대칭이 심한 경우에도 본 보정 방법이 유용하게 사용될 수 있음을 보여 주었다.

• 한국방사선학회논문지
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• 제14권5호
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• pp.677-684
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• 2020

CT 검사 시 좌,우 X축 방향의 Miscentering은 선량과 화질에 영향을 준다. CT Gantry Isocenter와 검사 목적부위의 Center가 일치되도록 Lateral Sliding Table을 이용하여 일치시켰을 때 화질은 더욱 좋아지고 피폭선량은 줄어든다. 중심 이탈에 따른 선량 비교 CTDI (mGy) 측정을 위하여 CTDI Head Phantom (Kimda, Korea)과 선량측정계(Ray Safe, Sweden)를 사용하였고, 중심 이탈에 따른 균일도의 차이를 보기 위한 노이즈의 측정은 Water Phantom (HITACHI, Japan) 을 사용하였다. 중심 이탈에 따른 선량 비교 CTDI(mGy)를 위해 선량을 측정한 결과 Isocenter 에서 X 축으로 20 mm 씩 이동하여 80 mm로 이동될때까지 지속적으로 선량이 적어졌고 정확한 선량이 입사되지 않았다. 중심 이탈에 따른 균일도의 차이를 보기 위해 SD값을 측정하였고 20 mm 씩 이동하여 80 mm로 이동될 때까지 지속적으로 노이즈가 커졌다. 콜리메이션의 범위는 중심이 탈된 범위만큼 콜리메이션 범위가 늘어났고 피폭의 범위가 커졌다. Lateral Sliding Table을 이용하면 Isocenter를 쉽게 맞출 수 있고, Isocenter에서 벗어난 위치의 심장검사, Extremity bone과 Shoulder같은 부위에서 Isocenter를 맞춰 영상의 화질을 높일 수 있고, Isocenter를 맞춰 콜리메이션을 대폭 축소하여 검사할 수 있으니 불필요한 피폭선량 감소에 활용할 수 있을 것으로 사료된다.

• 생물정신의학
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• 제3권1호
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• pp.57-65
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• 1996

The Evaluation of patients complaining of psychiatric symptoms following head injury is much affected by the results of various tests. The objecive of this paper is to investigate the effectiveness of each lest by comparing the structual and fuctional brain studies. The subjects were 93 organic menial disorder in and out patients at the Dept. of Neuropsychiatry of the Kyung Hee University Hospital. After carrying out MRI, CT, SPECT, EEG, the results of each were analysed for the sesitivity and ability to detect focal lesion. The degree of inter-test correlations of lest results were also investigated. Furthermore, the characteristic features of psychological tests were studied and the relationship between each of above mentioned tests and psychological test was examined. As for the test sensitivity to diagnosis, the SPECT was the most superior followed by MRI, CT, EEG in thai order. In the case of abnormality, SPECT ranked 1st in detection of focal lesion, followed by MRI, CT in that order. In the inter-test result correlation, the correlation of SPECT-MRI was statistically significant. When mare than moderate abnormality EEG finding was reported, it correlated significantly with that of MRI findings. In the MMPI, the average scores on F, Hs, D, Hy, Pa, Pt, Sc subscales were above 60. Abnormal SPECT group scored significantly high on the F, Pd, Pa, Sc, Ma scales and therefore in comparison ot the SPECT normal group, displayed more psychotic features. In K-WAIS, the mean full scale IQ was down to 77. 23(Verbal IQ : 78.76, Performance IQ : 77.44) but there was no characterogic significant relationship between the lowered to and abnormal SPECT, MRI, CT and EEG results. In conclusion, 1) The SPECT was mast superior in sensitivity and detection of focal lesions. In comparision with other tests, the results of SPECT correlated well with MRI had thus is thought to be very usefull testing method in the evaluation of organic mental disorder patients. 2) The MRI had relatively high sensitivity, ability to detect focal lesion and superior correlation with other test. 3) Although EEG fared less an sensitivity in comparison to other tests, the results of above moderate abnormal grade group and that of MRI correlated significantly. 4) In the MMPI highly scored in F, Hs, D, Hy, Pa, Pt, Sc subscales and abnormal SPECT patients were shown to display more sever psychotic features. There was no significant character relationship between the lowered IQ(in K-WAIS) and abnormal findings on MRI, CT, SPECT, EEG.

• 한국방사선학회논문지
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• 제8권6호
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• pp.357-364
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• 2014

전산화단층촬영장치의 영상재구성방법으로 필터보정역투영법이 광범위하게 사용되고 있다. 평행빔과 부채살빔의 재구성에 사용되는 투영에 잡음이 포함되었을 때 재구성 된 영상의 잡음을 살펴보았다. 평행빔과 부채살 구조에서 각각 360개, 720개의 투영으로 $512{\times}512$ 크기로 Visual C++을 이용하여 영상재구성하였고, 원본 Shepp-Logan 두부 모형을 매우 잘 복원한다는 것을 확인하였다. 필터보정역투영법의 현실적인 접근(유한한 투영 개수)으로 인해 입력 잡음이 없어도 영상재구성 과정에서 잡음이 발생하였다. 입력 잡음비 0.5% 이하에서 잡음이 빠르게 증가하기 때문에 CT 장치의 잡음 제거 기술 및 영상처리 기법의 개발이 필요할 것이다.

• IMMUNE NETWORK
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• 제12권6호
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• pp.261-268
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• 2012

Respiratory syncytial virus (RSV) and influenza virus are the most significant pathogens causing respiratory tract diseases. Composite vaccines are useful in reducing the number of vaccination and confer protection against multiple infectious agents. In this study, we generated fusion of RSV G protein core fragment (amino acid residues 131 to 230) and influenza HA1 globular head domain (amino acid residues 62 to 284) as a dual vaccine candidate. This fusion protein, Gcf-HA1, was bacterially expressed, purified by metal resin affinity chromatography, and refolded in PBS. BALB/c mice were intranasally immunized with Gcf-HA1 in combination with a mucosal adjuvant, cholera toxin (CT). Both serum IgG and mucosal IgA responses specific to Gcf and HA1 were significantly increased in Gcf-HA1/CT-vaccinated mice. To determine the protective efficacy of Gcf-HA1/CT vaccine, immunized mice were challenged with RSV (A2 strain) or influenza virus (A/PR/8/34). Neither detectable viral replication nor pathology was observed in the lungs of the immune mice. These results demonstrate that immunity induced by intranasal Gcf-HA1/CT immunization confers complete protection against both RSV and homologous influenza virus infection, suggesting our Gcf-HA1 vaccine candidate could be further developed as a dual subunit vaccine against RSV and influenza virus.

• Imaging Science in Dentistry
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• 제32권2호
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• pp.119-122
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• 2002

Two cases of Eagle's syndrome are reported. The first case involved a 31-year-old man who complained of pain in his throat and pain at preauricular area on turning his head. Panoramic and computed tomography (CT) views showed bilateral stylohyoid ligament ossification. The symptoms were relieved after surgical removal. The second case involved a 56-year-old female whose chief complaints were a continuous dull pain and occasional 'shooting' pain on lower left molar area. During the physical examination, an ossified stylohyoid ligament was palpated at the left submandibular area. Panoramic and CT images showed prominent bilateral stylohyoid ligament ossification. CT scans also showed hypertrophy of left medial and lateral pterygoid muscles. The symptoms were relieved after medication. CT is a useful tool for the examination of ossified stylohyoid ligaments and studying the relationship between Eagle's syndrome and adjacent soft tissue.

• Journal of Trauma and Injury
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• 제18권2호
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• pp.179-183
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• 2005

Whiplash injury commonly seen in automobile accident. This type of acceleration-deceleration injury may rarely lead to unfavorable outcomes as in the case of retropharyngeal hematoma. Because this lesion has the possibility of compressing the potential airway acutely or gradually, not only the rapid assessment and treatment but also closed observation are needed. We report a case of a 20-year-old man, who sustained a whiplash injury from contact with the headrest of his seat after his car was involved in a rollover. He had no symptom except posterior neck pain initially, but complained odynophagia and acute dyspnea after 10 hours of admission. The diagnostic work-up comprising lateral radiograph, CT imaging disclosed the rare constellation of a retropharyngeal hematoma with cervical spine fractures. Medical treatment and close observation were sufficient for the patient because he had no progressive dyspnea or major dysphagia.

• 대한두경부종양학회지
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• 제33권2호
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• pp.85-88
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• 2017

Mammary analogue secretory carcinoma (MASC) is a rare malignant tumor of the salivary gland, which was first described in 2010. In this case report, we describe a 62-year-old woman with a MASC of the parotid gland, who initially presented with an asymptomatic preauricular mass. At first, computed tomography (CT) and fine needle aspiration cytology were performed; these suggested a possible Warthin's tumor but also some suspicious malignant findings. For the main treatment, adequate parotidectomy was conducted via modified Blair incision to remove the tumor. Postoperative pathology report revealed a MASC of the parotid gland. Specific MASC findings were observed upon immunohistochemical examination.