• 건축사
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• 통권605호
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• pp.60-65
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• 2019

• 건축사
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• 통권613호
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• pp.64-69
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• 2020

• 건축사
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• 통권614호
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• pp.58-63
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• 2020

• Journal of Chest Surgery
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• 제47권4호
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• pp.350-357
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• 2014

Background: Conservation of blood during cardiac surgery is important because of the shortage of donor blood, risks associated with transfusion, and the costs of allogeneic blood products. This retrospective study explored the feasibility of off-pump coronary artery bypass (OPCAB) without transfusion. Methods: One hundred and two consecutive patients underwent OPCAB from January 2007 to June 2012 at Hallym University Sacred Heart Hospital. Excluding 10 chronic renal failures patients, 102 patients were enrolled. Their characteristics, clinical data, and laboratory data were analyzed. We investigated the success rate of OPCAB without transfusion according to preoperative hemoglobin (Hb), and the cutoff point of the Hb level and the risk factors for transfusion. We implemented multidisciplinary blood-saving protocols. Results: The overall operative mortality and the success rate of OPCAB without transfusion were 2.9% (3/102) and 73.5% (75/102). The success rates in patients with Hb<11, 11 70 years, diagnosis of acute myocardial infarction, preoperative Hb and creatinine levels, and operation time. The events precipitating the need for transfusion were low Hb level in 9 patients and hypotension or excessive bleeding in 18 patients. Conclusion: The preoperative Hb level of >11 facilitates OPCAB without transfusion. These results suggest that transfusion-free OPCAB can be performed by modifying the risk factors and correctable causes of transfusion and improving various blood salvage methods.

• 사상체질의학회지
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• 제25권4호
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• pp.359-372
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• 2013

Objectives The object of this study was to observe the effects of Hyeongbangjihwhang-tang (HB; Soyangin prescription) on the 5/6 NTX induced CRF rats. Methods Each of Hyeongbangjihwhang-tang aqueous extracts 200mg/kg were orally administered once a day for 35 days from 4 weeks after 5/6 NTX surgery. Four groups, each of 8 rats per group were used in this study, were sham group, CRF group, ${\alpha}$-Tocoperol group and HB group. Changes on the left remnant kidney weights, serum BUN, creatinine levels, caspase-3, PARP immunoreactivities were observed to nephroprotective effects, and relative immunomodulatory effects were monitored based on the changes of lymphatic organ weights and splenic cytokine contents. In addition, the changes on the kidney MDA, GSH contents and SOD, CAT activities were also calculated for antioxidant effects, and the effects on the CRF related cachexia were demonstrated based on the changes of body and epididymal fat pad weights, serum TG, TC, LDL and HDL levels. Results and Conclusions 1) HB was significantly decreased the left remnant kidney weights, serum BUN, creatinine levels and caspase-3, PARP immunoreactivities. 2) HB was significantly increased lymphatic organ weights and splenic cytokine contents. 3) HB was significantly increased body and epididymal fat pad weights, and was significantly decreased serum TG, TC, LDL and HDL levels. 4) HB was significantly decreased MDA contents, and was significantly increased GSH contents and SOD, CAT activities. The results obtained in this study suggest that HB significantly retarded immunosuppressions and cachexia related to the 5/6 NTX induced CRF through modulations of oxidative defense systems. Especially HB showed the highest favorable effects more than those of ${\alpha}$-tocoperol.

• Journal of Nutrition and Health
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• 제22권3호
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• pp.167-174
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• 1989

Vitamin B-2와 Vitamin B-6 결핍이 hematologic profile에 미치는 영향을 in vivo 계에서 알고보고자 하였다. 흰쥐에게 Vitamin B-2 결핍(-B2)식이, Vitamin B-6결핍(-B6)식이, Vitamin B-2와 Vitamin B-6복합 결핍(-B2-B6) 식이 또는 통제 식이를 6주 동안 공급한 후 희생시켜 Hematocrit (Ht), Hemoglobin(Hb), 혈장철 (PI), Transferrin포화도 (TS), 간장철 (LI)를 비교하였다. 통제군에 비하여 -B2군에서는 PI, TS, LI가 유의하게 낮았으나 Ht와 Hb은 유의한 차이가 없으며, -B6군에서는 Ht와 Hb는 유의하게 낮았으나 LI는 유의하게 높았다. 통제군에 비하여 -B2-B6군에서는 Hb, PI, TS, LI가 -B2군과 -B6군의 중간수준이었으며 Ht는 낮은 수준을 나타냈다. 2주간의 보충식이 후에는 -B2군과 -B6군에서 모든 혈액지표와 LI가 개선된 것으로 나타났다. 본연구의 결과는 Vitamin B-2와 Vitamin B-6의 섭취가 영양적 빈혈군에서 혈액 지표를 개선시켜 빈혈의 예방또는 치료에 중요하다는 것을 시사한다.

• 한국산학기술학회논문지
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• 제11권6호
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• pp.2263-2268
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• 2010

본 논문은 SDS-TWR(Symmetric Double-Sided Two_Way Ranging)의 Ranging 오차를 보정하여 위치인식 성 능을 향상시키는 방법으로 비컨노드의 거리별 Ranging 오차의 평균 값을 이용하여 Ranging 오차를 보정하는 알고리즘($CA_d$)과, 균등거리비율의 적용으로 Ranging 오차를 보정하는 알고리즘(AEDR)이 적용된 하이브리드형 위치인식 보정 알고리즘($A_{HB}$)을 제안하고, 위치인식 실험을 통해 성능을 분석하였다. 실험결과, $A_{HB}$ 는 전체 32개의 좌표 중 28개 좌표에서 오차 개선이 이루어졌고, 설정한 3개의 오차크기 영역에서 최소한 70%이상의 오차 개선이 이루어졌음을 확인하였다. 또한 32개 좌표에서 발생한 평균 오차 2.67m를 1.19m로 55.4% 보정하였으며 특히 3m 이상의 오차크기 영역에서의 보정 성능은 90% 이상으로 매우 우수함을 확인하였다. 이와 같은 결과를 볼 때, $A_{HB}$ 는 $CA_d$와 AEDR이 각각 수행되었을 때 보다 오차 개선 비율 및 보정 성능이 더 우수함을 확인하였다.

• 천문학논총
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• 제13권1호
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• pp.149-166
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• 1998

The structure and environments of the molecular clouds near the SNR $HB3(G132.7\pm1.3)$ are studied. The molecular complex which is located at the southern rim of HB3 was proposed by former investigators as the one interacting with HB3. This complex region of $2^{\circ}\times2^{\circ}\;at\;l=133^{\circ}$ has been observed at $^{12}CO,\;^{13}CO,\;J=1-0\;at\;a\;1'$, resolution with the 14-m radio telescope at Taeduk Radio Astronomy Observatory. We have reached to the following four conclusions. The possibility that these molecular complex and HB3 are interacting with each other cannot be supported with any of our data. The morphologies of the two show no similarities. Neither particular features for the interaction are found in the CO lines. The hypothetical 'Molecular wall' which was expected to exist on the northwestern rim of HB3 as a cause for the noncircular morphology of HB3 is turned out to be nonexistent in CO. The molecular complex which resembles a 'bar' at a low resolution is now resolved into a U-shaped shell. It seems that the U-shape is consist of two independent components. No peculiarities, such as unseen masses or bright stars capable of forming HlI regions, are found within the U-shape region. The total mass included in the complex is estimated to be $M_{total}\;=\;2.9\~8.4\times10^5\;M_\bigodot$, which is in good agreement with previous observations within errors. Considering about 12 clumps distinguishable within the complex, the total mass implies that masses of each of clumps are on the order of $10^4\;M_\bigodot$, which makes these good objects for further studies in relation to star-formation. Especially the clumps associated with W3 are worthy for more high resolution observations for better understanding of astrophysical phenomenon ongoing in them.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3187-3190
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• 2012

This study evaluated the relationship between pretreatment hemoglobin (Hb) and prognostic factors in Thai patients with endometrial cancer. Medical records of 228 patients who had undergone surgery between January 2005 and December 2007 were retrospectively reviewed. Associations between clinicopathological variables and pretreatment Hb levels were described using Pearson's chi square test or two-tailed Fisher's exact test. Survival analysis was performed with Kaplan-Meier estimates. Univariate and Cox-regression models were used to evaluate the prognostic impact of various factors, including Hb levels, in term of disease-free survival. The median duration of follow-up was 38.2 months. Eighty-nine patients (39%) had a preoperative Hb level of <12 g/dL, these having significantly higher rates of non-endometrioid histology, advanced FIGO stage, lymphovascular space invasion, cervical involvement, adnexal involvement, positive peritoneal cytology, and lymph node involvement than patients with Hb ${\geq}12$ g/dL. The 5-year disease-free and overall survival were significantly lower in patients with pretreatment Hb levels <12 g/dL compared with those with Hb ${\geq}12$ g/dL (79.3% vs. 89.2%, p=0.044 and 87.6% vs. 99.3%, p<0.001, respectively). In the multivariate analysis only histology, myometrial invasion, and lymphovascular invasion proved to be independent prognostic factors, whereas tumor grading, stage, cervical involvement, adnexal involvement, positive peritoneal cytology, lymph node involvement, and low Hb were not. In conclusion, presence of anemia before treatment may reflect poor prognostic factors in patients with endometrial cancer and low pretreatment hemoglobin level may have a prognostic impact on clinical outcome.

• 한국미생물·생명공학회지
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• 제24권1호
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• pp.92-100
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• 1996

For the production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(P(3HB-co-3HV)) from butyric acid and valeric acid, 10 strains of bacteria capable of producing P(3HB-co-3HV) were isolated from soil. Among them, the strain HJ-067 showed the best ability of producing P(3HB-co-3HV), and was indentified as a Azotobacter sp. For the production of P(3HB-co-3HV), the optimum concentrations of butyric and valeric acid were 3.0g/l, respectively. The most effective nitrogen source was $(NH_4)_{2}SO_4$ at an optimum concentration of 0.75g/l, which was equivalent to 21.36 in C/N ratio. Deficiency of the cationic metal ions ($Zn^{2+},\;Co^{2+},\;Mn^{2+}$) in the proguction medium had stimulating effect on P(3HB-co-3HV) accumulation, especially in the manganese. deficient medium. The optimum temperature for P(3HB-co-3HV) production was 27$^{\circ}C$ and the optimum initial pH was 7.0. Under the optimum conditions, 1.82g/l of P(3HB-co-3HV) and 3.00g/l of dry biomass were produced after 36 hour cultivation, and the P(3HB-co-3HV) yield and HV% were 60.60% (w/w), 15.92%, respectively.