• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.5
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• pp.215-221
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• 2020

Adulterated herbal medicine is intentionally added with undeclared improper or inferior ingredients which should not be in herbal medicine. The contamination with potentially hazardous substances such as heavy metal, pesticides, fungus, and microorganism sometimes can be regarded as one of adulteration in a broad sense. The problem of adulteration is that adulterated herbal medicine shows poor quality and/or can cause adverse events. Therefore, it is important to control adulteration issues for quality assurance and qualitative improvement of herbal medicines. This study aims to summarize and make a reference how to control adulterated herbal medicine. In this process, this study is to investigate studies about adulterated herbal medicine via searching Korean and foreign electronic databases such as PubMed, NDSL and OASIS. Finally eighteen papers were included to this study and analyzed according to the type of study, the category and efficacy of adulterants, the type of analysis methodologies and possible adverse events of adulterants. Phosphodiesterase type 5 (PDE-5) inhibitors for male sexual enhancement and anorexic, laxative, diuretic agents for weight loss and treating obesity has been used frequently as adulterants. The range of adverse event caused by adulterated herbal medicine were very wide from mild symptoms such as diarrhea, constipation, dizziness and blurred vision to very severe symptoms such as heart failure, hypoglycemia and renal impairment. This study showed the recent trend on the research of adulterated herbal medicine and this will be the ground to develop more detailed systems to control adulterated herbal medicine.

• Journal of Advanced Navigation Technology
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• v.20 no.2
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• pp.148-154
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• 2016

Safety assessment is necessary to develop safety related CNS/ATM system. It includes functional hazard assessment (FHA), effects eliciting system safety requirement that mitigates system's hazardous event. This paper performs a case study for functional hazard assessment of A-SMGCS. To do this, related A-SMGCS studies from Eurocontrol and EMMA are surveyed, and assessment schemes of functional hazard from Eurocontrol and EMMA are combined. Not only FHA scope but also several assumptions for FHA are defined for Incheon airport. 29 hazards are identified and their severities are assessed. And exposures and safety objectives from hazards are analyzed using event tree analysis method. Differences between result of this study and result of EMMA are analysed, and assessment results in this study are also reviewed.

• Journal of Korean Society of Transportation
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• v.36 no.1
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• pp.51-65
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• 2018

Intentional aggressive driving (IAD) is defined as a hazardous driving event that the aggressive driver intentionally threatens neighbor drivers with abrupt longitudinal and lateral maneuvering. This study developed a methodology for detecting IAD events based on the analysis of interactions between aggressive driver and normal driver. Three major aggressive events including rear-close following, side-close driving, and sudden deceleration were analyzed to develop the algorithm. Then, driving simulation experiments were conducted using a multi-agent driving simulator to obtain data to be used for the development of the detection algorithm. In order to detect the driver's intention to attack, a relative evaluation index (Erratic Driving Index, EDI) reflecting the driving pattern was derived. The derived IAD event detection algorithm utilizes both the existing absolute detection method and the relative detection method. It is expected that the proposed methodology can be effectively used for detecting IAD events in support of in-vehicle data recorder technology in practice.

• Journal of the Korean Society of Safety
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• v.37 no.2
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• pp.1-9
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• 2022

Most factories deal with toxic or flammable chemicals in their industrial processes. These hazardous substances pose a risk of leakage due to accidents, such as fire and explosion. In the event of chemical release, massive casualties and property damage can result; hence, quantitative risk prediction and assessment are necessary. Several methods are available for evaluating chemical dispersion in the atmosphere, and most analyses are considered neutral in dispersion models and under far-field wind condition. The foregoing assumption renders a model valid only after a considerable time has elapsed from the moment chemicals are released or dispersed from a source. Hence, an initial dispersion model is required to assess risk quantitatively and predict the extent of damage because the most dangerous locations are those near a leak source. In this study, the dispersion model for initial consequence analysis was developed with three-dimensional unsteady advective diffusion equation. In this expression, instantaneous leakage is assumed as a puff, and wind velocity is considered as a coordinate transform in the solution. To minimize the buoyant force, ethane is used as leaked fuel, and two different diffusion coefficients are introduced. The calculated concentration field with a molecular diffusion coefficient shows a moving circular iso-line in the horizontal plane. The maximum concentration decreases as time progresses and distance increases. In the case of using a coefficient for turbulent diffusion, the dispersion along the wind velocity direction is enhanced, and an elliptic iso-contour line is found. The result yielded by a widely used commercial program, ALOHA, was compared with the end point of the lower explosion limit. In the future, we plan to build a more accurate and general initial risk assessment model by considering the turbulence diffusion and buoyancy effect on dispersion.

• Fire Science and Engineering
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• v.15 no.1
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• pp.84-92
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• 2001

In today's world, rise in the establishment of social infrastructure resulting from population saturation in large cities has led to more extensive and frequent use of chemical materials on facilities. A result, unexpected and serious accidents, hazards, contingencies and disasters are more prevalent than ever. Such phenomenon calls for more devoted and concerted efforts towards finding ways to reduce the safety hazards that are seen to take place more often than before with the increase in the number of facilities that are prone to bring disaster and hazard coupled with the conventional safety problems that continue to exist even today. In developed countries, such challenge is addressed by various appropriate countermeasures drawn up by local professional committees on industrial facilities, whose members conduct offsite and onsite evaluation un the potential industrial disasters and its seriousness and provide their advice thereof. Against this backdrop, this study aims at identifying a comprehensive safety allowance level (safety acceptable level) when imposing limitation on the development of conventional or new facilities, for the fur pose of establishing a safety allowance level of disastrous and dangerous facilities in Korea. This is done by assessing and applying the level of danger each individual is exposed to in a randomly selected region (disastrous and dangerous areas in Seoul) based on probability of quantitative hazards, as well as simulation and calculation methods which include: i) social disaster evaluation method applying Quantified Risk Assessment of Health & Safety Executive of UK and Matrix of Risk of Evaluated Sources of Hazard; ii) Fault Tree or Event Tree Analysis and etc.

• Korean Chemical Engineering Research
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• v.57 no.1
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• pp.42-50
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• 2019

As the industry develops in Korea, the use of hazardous chemicals is increasing rapidly and chemical accidents are increasing accordingly. Most of the chemical accidents are caused by leaks of hazardous chemicals, but there are also accidents in which all the substances are released instantaneously due to sudden high temperature/pressure or defection of the storage tanks. This is called catastrophic failure and its frequency is very low, but consequence is very huge when it occurs. In Korea, there were 15 casualties including three deaths due to catastrophic rupture of water tank in 2013, and 64 instances of failures from 1919 to 2004 worldwide. In case of catastrophic failure, it would be able to overflow outside the bund that reduces the evaporation rate and following consequence. This incident is called overtopping. Overseas, some researchers have been studying the amount of external overflow depending on bund conditions in the event of such an accident. Based on the previous research, this study identified overtopping fraction by condition of bund in accordance with Korea Chemicals Controls Act Using CFD simulation. As a result, as the height increases and the distance to the facility decreases while meeting the minimum standard of the bund capacity, the overtopping effect has decreased. In addition, by identifying the effects of overtopping according to atmospheric conditions, types of materials and shapes of bunds, this study proposes the design of the bund considering the effect of overtopping caused by catastrophic failure with different bund conditions.

• The Journal of the Convergence on Culture Technology
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• v.10 no.2
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• pp.407-417
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• 2024

The objective of this study is to predict and reduce potential damage caused by chlorine gas leaks, a hazardous material, when vehicles transporting it overturn due to accidents or other incidents. The goal is to forecast the anticipated damages caused by chlorine toxicity levels (ppm) and to design effective response strategies for mitigating them. To predict potential damages, we conducted quantitative assessments using the ALOHA program to calculate the toxic effects (ppm) and damage distances resulting from chlorine leaks, taking into account potential negligence of drivers during transportation. The extent of damage from toxic gas leaks is influenced by various factors, including the amount of the leaked hazardous material and the meteorological conditions at the time of the leak. Therefore, a comprehensive analysis of damage distances was conducted by examining various scenarios that involved variations in the amount of leakage and weather conditions. Under intermediate conditions (leakage quantity: 5 tons, wind speed: 3 m/s, atmospheric stability: D), the estimated distance for exceeding the AEGL-2 level of 2 ppm was calculated to be 9 km. This concentration poses a high risk of respiratory disturbance and potential human casualties, comparable to the toxicity of hydrogen chloride. In particular, leaks in urban areas can lead to significant loss of life. In the event of a leakage incident, we proposed a plan to minimize damage by implementing appropriate response strategies based on the location and amount of the leak when an accident occurs.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.718-725
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• 2017

A liquid storage tank is one of the most important structures in industrial complexes dealing with chemicals, and its structural damage due to an earthquake may cause a disastrous event such as the leakage of hazardous materials, fire, and explosion. It is thus essential to assess the seismic fragility of liquid storage tanks and prepare for seismic events in advance. When a liquid storage tank is oscillated by a seismic load, the hydrodynamic pressure caused by the liquid-structure interaction increases the stress and causes structural damage to the tank. Meanwhile, the seismic fragility of the structure can be estimated by considering the various sources of uncertainty and calculating the failure probabilities in a given limiting state. To accurately evaluate the seismic fragility of liquid storage tanks, a sophisticated finite element analysis is required during their reliability analysis. Therefore, in this study, FERUM-ABAQUS, a recently-developed computational platform integrated with commercial finite element and reliability analysis software packages, is introduced to perform the finite element reliability analysis and calculate the failure probability of a liquid storage tank subjected to a seismic load. FERUM-ABAUS allows for automatic data exchange between these two software packages and for the efficient seismic fragility assessment of a structure. Using this computational platform, the seismic fragility curve of a liquid storage tank is successfully obtained.

• Journal of the Korean Institute of Gas
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• v.23 no.4
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• pp.1-9
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• 2019

Large-scale industrial boilers operating at high temperature and high pressure, have a large amount of water, and a large amount of energy is released at the time of explosion. Currently, most industrial boilers use gas fuel such as LNG and LPG, etc. and fuel exists in the same space as equipment, so there is a high possibility of secondary damage such as fire or explosion in the event of a boiler accident. Both special care and management are required to operate the very dangerous equipment that causes casualty 2.51 per accident. For boilers of a certain size or more, the Korea Energy Agency conducts inspections in accordance with the Energy Usage Rationalization Act, KS, and public notice of the Ministry of Industry, Trade and Resources. In this research, based on the results of the inspection, the hazard factorss are configured, and a questionnaire is conducted to the inspector, the equipment manager, the maintenance person, and the person in charge of the manufacturer. We analyzed the results by using AHP (Analytic Hierarchy Process). As a result of analysis, generally recognized hazard factorss are not good management, measurement failure, specification failure, water leak, leak analysis, but connection, welding, scale, and corrosion, etc. are relatively less important. It is judged that the adverse factors that are recognized to be highly important among all groups and careers are already well managed, but less important and adverse factors should be well managed to ensure that the safe usage of the boiler.