• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제55권12호
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• pp.661-666
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• 2006

Interlocking signalling system plays key role as core system to manage railway operation. The core role of railway operation is to control routing, displaying signal and regulation for train. Interlocking system relate tightly to railway accident because collision and derailment is sometime taken place wrong route setting and signal displaying. Safety activity for interlocking system is inevitable to avoid the accident over its life cycle. The safety activity includes hazard identification and analysis, safety requirement allocation, safety plan, safety activity and ao on. The safety activity need a broad wide range work. In this paper, we concentrate on hazard identification for generic interlocking system and programmable electronic interlocking system and compare between two results. The hazards will be used for safety activity.

• Journal of Advanced Research in Ocean Engineering
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• 제3권3호
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• pp.125-135
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• 2017

The paper considers the practical application of the FMEA(Failure Mode and Effect Analysis) method to assess the operational reliability of the LNG(Liquefied Natural Gas) transfer system, which is a potential problem for the connection between the LNG FPSO and LNG carrier. Hazard Identification (HAZID) and Hazard operability (HAZOP) are applied to identify the risks and hazards during the operation of LNG transfer system. The approach is performed for the FMEA to assess the reliability based on the detection of defects typical to LNG transfer system. FTA and FMEA associated with a probabilistic risk database to the operation scenarios are applied to assess the risk. After providing an outline of the safety assessment procedure for the operational problems of system, safety assessment example is presented, providing details on the fault tree of operational accident, safety assessment, and risk measures.

• 한국산업보건학회지
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• 제25권4호
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• pp.506-515
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• 2015

Objectives: This study was conducted to evaluate the status of hazard communication regarding dental materials among dental hygienists in the Daegu Metropolitan City and the North Gyeongsang-do Province area. Materials: A total of 310 dental hygienists were surveyed using self-administered questionnaires to investigate the status of hazard communication on dental materials and information needs. We collected instructions for use and material safety data sheets(MSDSs) for 67 dental materials frequently used at dental hospitals located in the Daegu Metropolitan City and the North Gyeongsang-do Province area. Results: The questionnaire surveys showed that only 11% of the 310 dental hygienists had knowledge of MSDS and 46.8% of respondents never read instructions for use before using materials. Just 7.4% of dental hygienists have undergone training on hazard information for dental materials. In particular, dental hygienists working at dental clinics had significantly lower response rates on knowledge of MSDS(p<0.001), reading of instructions for use(p=0.042) and training on the hazard information of dental materials(p=0.004) than those in dental hospitals or general hospitals. The essential information most desired by dental hygienists was hazard identification(82.3%) followed by first-aid measures(53.9%), handling and storage(51%), disposal considerations (49%) and toxicological information(47.1%). All dental materials were on foreign products which came from Japan(59.7%), the USA(26.9%) and Liechtenstein(13.7%). In terms of usage, 56.7% of dental materials were prosthetic, followed by conservation(31.3%), orthodontics(9%), and prevention(3%). We found that dental hygienists had accessed MSDSs for only five dental products among the 67 dental materials. The instructions for the use of the 67 dental materials provided hazard identification(64.2%), first-aid measures(83.6%), handling and storage(97%), disposal considerations(20.9%) and toxicological information(26.9%). Conclusions: Based on the results of this study, the hazard communication system for dental hygienists working at dental clinics should be improved.

• 정보과학회 논문지
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• 제43권6호
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• pp.662-667
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• 2016

차량 내 전기전자제어시스템이 급격히 증가하면서 이로 인한 안전사고가 이슈로 부각되고 있다. 그러므로 차량의 안전성을 확보하기 위해서는 개발 초기에 PHA, HAZOP 등을 활용하여 위험원을 식별하고, 이를 예방하기 위한 안전 메커니즘이 구현되어야 한다. 특히, HAZOP은 가이드워드 기반의 체계적인 방식으로 널리 활용되고 있다. 하지만, 시스템이 제공하는 최상위 기능으로부터 오동작을 찾아내기 때문에, 동작 과정상의 위험원을 충분히 식별하지 못한다. 또한 충분히 식별되지 않은 위험원으로부터 안전 요구사항을 정의하기 때문에 테스트케이스 설계에도 제한이 있다. 이에 본 연구에서는 시스템의 동작과정 정의에 유용한 사용사례 기술서와 HAZOP을 적용한 위험원 식별 그리고 안전 요구사항 기반의 테스트케이스 설계 방안을 제안한다. 본 연구의 효용성을 검증하기 위해 차량의 스마트키 제어시스템 사례를 제시하고, 기존 HAZOP 기반의 위험원 분석 결과와 비교한다. 본 연구를 적용하는 조직은 시스템 개발 초기에 위험원 및 안전 요구사항을 충분히 식별하고, 테스트케이스를 설계함으로써 개발 비용을 줄이고, 시스템 품질을 높일 수 있을 것으로 기대한다.

• Molecules and Cells
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• 제44권9호
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• pp.647-657
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• 2021

As a pancreatic inflammatory marker, regenerating islet-derived protein 3A (Reg3A) plays a key role in inflammation-associated pancreatic carcinogenesis by promoting cell proliferation, inhibiting apoptosis, and regulating cancer cell migration and invasion. This study aimed to reveal a novel immuno-regulatory mechanism by which Reg3A modulates tumour-promoting responses during pancreatic cancer (PC) progression. In an in vitro Transwell system that allowed the direct co-culture of human peripheral blood-derived dendritic cells (DCs) and Reg3A-overexpressing/ silenced human PC cells, PC cell-derived Reg3A was found to downregulate CD80, CD83 and CD86 expression on educated DCs, increase DC endocytic function, inhibit DC-induced T lymphocyte proliferation, reduce IL-12p70 production, and enhance IL-23 production by DCs. The positive effect of tumour-derived Reg3A-educated human DCs on PC progression was demonstrated in vivo by intraperitoneally transferring them into PC-implanted severe combined immunodeficiency (SCID) mice reconstituted with human T cells. A Reg3A-JAK2/STAT3 positive feedback loop was identified in DCs educated with Reg3A. In conclusion, as a tumour-derived factor, Reg3A acted to block the differentiation and maturation of the most important antigen-presenting cells, DCs, causing them to limit their potential anti-tumour responses, thus facilitating PC escape and progression.

• 한국안전학회지
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• 제26권6호
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• pp.111-117
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• 2011

Risk-based railway safety management has been mandatory in Korea as by relevant laws and regulations enacted since the Railway Safety Act 2004. In particular, the Railway Vehicle Safety Guidance came into effect on Jan 1, 2008 specifies the details of methodology for hazard analysis, risk assessment and safety verification and validation. Fundamentals for success of the risk-based safety management are systematic hazard identification and risk assessment by use of reasonable risk assessment criteria, but the principle of risk-based safety management has not been applied in an effective way to introduction and maintenance of railway vehicle systems because definite risk assessment criteria have not been set down for each railway system or railway network. The purpose of this study is to suggest a risk matrix development principle for risk assessment of domestic urban metro vehicles by analyses of relevant rules and railway operating environment of Korea.

• Safety and Health at Work
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• 제12권3호
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• pp.317-323
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• 2021

Background: The surface mining industry has one of the highest fatality rates among private industries in the United States. Despite recent decreases in the fatality rates of comparable industries, the fatality rate in the surface mining industry has increased. Meanwhile, a lack of safety research in surface mining has hindered efforts to improve safety strategies in the surface mining workplace. Method: This study examined quarry workers' hazard identification skills by conducting a case study of a surface mining facility in the Mid-Atlantic region of the United States. Semistructured interviews were conducted with eight quarry workers who were employed at the mine facility. In addition to the interviews, data were collected through field notes, notes from an expert meeting with safety managers, and site photographs to explore quarry workers' safety behaviors in the workplace. Results: The results showed that quarry workers identified hazards and improved their safety performance by translating safety knowledge learned from training into practice, acquiring hands-on work experience, learning from coworkers, and sharing responsibilities among team members. Conclusion: This study contributes to understanding quarry workers' safe performance beyond what they have learned in safety training to include their interaction with other workers and hand-on experience in the workplace. This study informs practitioners in the surface mining industry to build a safe work environment as they design effective safety programs for employees.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.458-464
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• 2022

Hazard recognition is considered as one of the pre-requisites for effective hazard management and injury prevention. However, in complex and changing environments, construction workers are often unable to identify all possible hazards that can occur in the jobsite. Therefore, identification of factors that impact hazard recognition in the work environment is necessary to reduce safety incidents as well as to develop strategies that can improve worker's hazard recognition performance. This study identified factors/problems that impact worker's hazard recognition abilities and suggested some potential technologies that can mitigate such problems. Literature reviews of journal articles and published reports related to hazard recognition studies were conducted to identify the factors. The study found out that the major factor responsible for affecting worker's hazard recognition abilities were human-related. Industry factors, Organizational factors and Physical factors of the site were the other factors identified from the study that impact worker's hazard recognition performances. The findings from the study can help site personnel recognize areas where effective measures can be directed towards worksite safety of workers while working in complex construction environments.

• 국제학술발표논문집
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• The 4th International Conference on Construction Engineering and Project Management Organized by the University of New South Wales
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• pp.17-22
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• 2011

A considerable number of construction disasters occur on pathways. Safety management is usually performed on construction sites to prevent accidents in activity areas. This means that the safety management level of hazards on pathways is relatively minimized. Many researchers have noted that hazard identification is fundamental to safety management. Thus, algorithms for helping safety managers to identify hazardous areas are developed using automated data collection technology. These algorithms primarily search for potential hazardous areas by comparing workers' location logs based on a real-time location system and optimal routes based on BIM. Potential hazardous areas are filtered by identified hazardous areas and activity areas. After that, safety managers are provided with information about potential hazardous areas and can establish proper safety countermeasures. This can help to improve safety on construction sites.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 춘계학술대회 논문집
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• pp.936-940
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• 2007

This paper is about the study on the verification method for railway system SIL which is frequency of hazard, composing Risk, one of the measurement standards for railway system safety. Frequency of hazard can be identified by using FMECA, or HAZOP, and the assessment of identified dangerous failure rate should be done by systematic methods such as FTA. Therefore, this paper provides the hazard identification level for SIL verification and the requirements necessary to verify the integrity of analysis activity.