• Title/Summary/Keyword: Hazard Factor

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Racial and Socioeconomic Disparities in Malignant Carcinoid Cancer Cause Specific Survival: Analysis of the Surveillance, Epidemiology and End Results National Cancer Registry

  • Cheung, Rex
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7117-7120
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    • 2013
  • Background: This study hypothesized living in a poor neighborhood decreased the cause specific survival in individuals suffering from carcinoid carcinomas. Surveillance, Epidemiology and End Results (SEER) carcinoid carcinoma data were used to identify potential socioeconomic disparities in outcome. Materials and Methods: This study analyzed socioeconomic, staging and treatment factors available in the SEER database for carcinoid carcinomas. The Kaplan-Meier method was used to analyze time to events and the Kolmogorov-Smirnov test to compare survival curves. The Cox proportional hazard method was employed for multivariate analysis. Areas under the receiver operating characteristic curves (ROCs) were computed to screen the predictors for further analysis. Results: There were 38,546 patients diagnosed from 1973 to 2009 included in this study. The mean follow up time (S.D.) was 68.1 (70.7) months. SEER stage was the most predictive factor of outcome (ROC area of 0.79). 16.4% of patients were un-staged. Race/ethnicity, rural urban residence and county level family income were significant predictors of cause specific survival on multivariate analysis, these accounting for about 5% of the difference in actuarial cause specific survival at 20 years of follow up. Conclusions: This study found poorer cause specific survival of carcinoid carcinomas of individuals living in poor and rural neighborhoods.

Logical Consistency in Risk Assessment using the Korean Fuzzy Linguistic Variables (한국어 퍼지 언어변수를 이용한 리스크 평가의 논리적 일관성)

  • Lim, Hyeon-Kyo;Byun, Sanghun
    • Journal of the Korean Society of Safety
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    • v.31 no.4
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    • pp.120-125
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    • 2016
  • Usually, a risk can be expressed as a product of likelihood and consequence of a hazard factor. Therefore, conventional risk assessment is carried out by frequency analysis and severity analysis, in turns. However, it is well known that intuitive thinking is another excellent way of thinking of human beings. This study aimed to confirm whether there exist any difference in risk assessment results derived by two different procedures - intuitive and analytical. Thus, the present study showed 10 different illustrations to 30 undergraduate students. Their responses were organized as fuzzy membership functions, and summarized as risk assessments, and compared. The results were also verified with the help of statistical hypothesis testing, which showed no significant difference. On the contrary, however, similarity measure used in fuzzy set theory was not credible as anticipated. Many cases failed to satisfy statistical hypothesis even with similarity measure higher than 0.60 so that only a trend could be accepted. In addition, a subject showed a somewhat consistent logical discrepancy in his response, which implied the necessity of sincere analysis in fuzzy formulations.

Allocation of Safety Integrity Level for Railway Platform Screen Door System considering Semi-Quantitative Risk Reduction Factor (반 정량적 리스크 저감 요소를 고려한 철도 승강장 스크린 도어시스템의 안전 무결성 수준 할당)

  • Song, Ki Tae;Lee, Sung Ill
    • Journal of the Korean Society of Safety
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    • v.31 no.4
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    • pp.156-163
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    • 2016
  • There exists required safety integrity level (SIL) to assure safety in accordance with international standards for every electrical / electronics / control equipment or systems with safety related functions. The SIL is allocated from lowest level (level 0) to highest level (level 4). In order to guarantee certain safety level that is internationally acceptable, application of methodology for SIL allocation and demonstration based on related international standards is required. However, the theoretical and practical study for safety integrity level is barely under way in the domestic railway industry. This research studied not only the global process of SIL allocation to guarantee safety in accordance with international standards for safety related equipment and system, but the quantitative methodology based on international standard and the semi-quantitative methodology as alternative way for SIL allocation. Specifically, the systematic SIL allocation for platform screen door system of railway is studied applying the semi-quantitative methodology in order to save much time and effort compared to quantitative method.

PRODUCTION OF GROUND SUBSIDENCE SUSCEPTIBILITY MAP AT ABANDONED UNDERGROUND COAL MINE USING FUZZY LOGIC

  • Choi, Jong-Kuk;Kim, Ki-Dong
    • Proceedings of the KSRS Conference
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    • v.2
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    • pp.717-720
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    • 2006
  • In this study, we predicted locations vulnerable to ground subsidence hazard using fuzzy logic and geographic information system (GIS). Test was carried out at an abandoned underground coal mine in Samcheok City, Korea. Estimation of relative ratings of eight major factors influencing subsidence and determination of effective fuzzy operators are presented. Eight major factors causing ground subsidence were extracted and constructed as a spatial database using the spatial analysis and the probability analysis functions. The eight factors include geology, slope, landuse, depth of mined tunnel, distance from mined tunnel, RMR, permeability, and depth of ground water. A frequency ratio model was applied to calculate relative rating of each factor, and the ratings were integrated using fuzzy membership function and five different fuzzy operators to produce a ground subsidence susceptibility map. The ground subsidence susceptibility map was verified by comparing it with the existing ground subsidences. The obtained susceptibility map well agreed with the actual ground subsidence areas. Especially, ${\gamma}-operator$ and algebraic product operator were the most effective among the tested fuzzy operators.

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The Removal Properties of NO Using KOH-Treated ${\gamma}$ -Alumina (KOH로 처리된 ${\gamma}$} -Alumina를 이용한 NO의 제거특성)

  • 모세영;김만수;장홍기;안대현;손종렬
    • Journal of environmental and Sanitary engineering
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    • v.16 no.3
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    • pp.104-110
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    • 2001
  • NOx coming from combustion make photochemical smog and acid rain, cause chronic respiratory disease resulting in critical hazard to environment and human health. Most composition of NOx coming from combustion is NO and the remaining small amount of $NO_x$ is $NO_2$. Currently, many technologies are developed and used to control NO release. One of these technologies is control technology through use of the adsorbent. In this study, two methods were used to make the adsorbent and compared. KOH and ${\gamma}{\;}-alumina$ were mixed by using two methods. Then, the experimental conditions were as follows: the concentrations of KOH used were 1 mole, 0.5 mole, and 0.1 mole, respectively and the amount of ${\gamma}{\;}-alumina$$250^{\circ}C$. As a result, precipitation method, which is one of the production methods of the adsorbent, showed the most removal efficiency as KOH concentration as 1 mole and reaction temperature as $100^{\circ}C$ were used. This study shows 40 to 60% of micropores of ${\gamma}{\;}-alumina$ was lost by the reaction with KOH through the analysis of SEM and BET Finally, KOH is the most predominant factor to control the removal of NO rather than micropore of the adsorbent.

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China's Brain Gain at the High End: An Assessment of Thousand Youth Talents Program

  • Sun, Yutao;Guo, Rongyu;Zhang, Shuai
    • Asian Journal of Innovation and Policy
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    • v.6 no.3
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    • pp.274-294
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    • 2017
  • While studies have viewed the effect of Chinese talent-attracting programs launched by government since reform and open door policy, little of them has assessed these programs empirically and pertinently. This article intends to assess an important program - the Thousand Youth Talents Program (TYTP). Frist, this paper proposed a transnational migration matrix of the academics to clarify the dynamic mechanism of academic brain gain at the high end. Then, the Kaplan-Meier analysis and Cox regression model are used to empirically analyze the policy effect of TYTP. The results show that, academic ability have double edged impacts on brain gain at the high end, some scholars whose last employer's academic ranking is world's Top100 have stronger willing to return, and the negative effect of academic ranking decreases with time passing; while scholars with a tenure-track position, a tenure position or a permanent position tend to stay overseas, and the hazard rate of staying increases with age. The older scholars have more intentions to go back China, while gender was not a significant factor influencing academic return at the high end. That is, the talent-attracting programs has partly succeeded in bringing back the academics at the high end.

Factors Affecting Survival Time of Cholangiocarcinoma Patients: A Prospective Study in Northeast Thailand

  • Woradet, Somkiattiyos;Promthet, Supannee;Songserm, Nopparat;Parkin, Donald Maxwell
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.1623-1627
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    • 2013
  • Cholangiocarcinoma (CCA) is a major health problem and cause of death among people in Northeastern Thailand. In this prospective study 171 patients newly diagnosed with CCA by physicians in 5 tertiary hospitals in four provinces of northeastern of Thailand between February and July 2011 were followed up to January 2012. The outcome was survival time from diagnosis to death. A total of 758.4 person-months of follow-up were available. The mortality rate was 16.9 per 100 person-months (95%CI: 14.1-20.1). The median survival time among CCA patients was 4.3 months (95%CI: 3.3-5.1). Cox's proportional hazard model was used to study the independent effects of factors affecting survival time among patients. Statistically significant factors included advanced stage at diagnosis (HR: 2.5, 95%CI: 1.7-3.8), presentation with jaundice (HR: 1.7, 95%CI: 1.1-2.4) or ascites (HR: 2.8, 95%CI: 1.8-4.4), and positive serum carcinoembryonic antigen (HR: 2.3, 95%CI: 1.2-4.3). Patients who had received standard treatment had a better prognosis that those who did not (HR: 0.5, 95%CI: 0.3-0.7).

The Study of Criminal Lingo Analysis on Cyberspace and Management Used in Artificial Intelligence and Block-chain Technology

  • Yoon, Cheolhee;Lee, Bong Gyou
    • International Journal of Advanced Culture Technology
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    • v.8 no.3
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    • pp.54-60
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    • 2020
  • Online cybercrime has various causes. The criminal guilty language, Criminal lingo is active in the shaded area with the bilateral aspect of the word on cyber. It has been continuously producing massive risk factors in cyberspace. Criminals are shared and disseminated online. It has been linked with fake news and aids to suicide that has recently become an issue. Thus the criminal lingo has become a real danger factor on cyber interface. Recently, Criminal lingo is shared and distributed as cyber hazard information. It is transformed that damaging to the youth and ordinary people through the internet and social networks. In order to take action, it is necessary to construct an expert system based on AI to implement a smart management architecture with block-chain technology. In this paper, we study technically a new smart management architecture which uses artificial intelligence based decision algorithm and block-chain tracking technology to prevent the spread of criminal lingo factors in the evolving cyber world. In addition, through the off-line regular patrol program of police units, we proposed the conversion of online regular patrol program for "cyber harem area".

Initial Diagnosis of Functional Gastrointestinal Disorders in Children Increases a Chance for Resolution of Symptoms

  • Trivic, Ivana;Hojsak, Iva
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.21 no.4
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    • pp.264-270
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    • 2018
  • Purpose: The aim of this study was to describe functional gastrointestinal disorders (FGID) presented in a tertiary medical center, characteristics of patients and results of the diagnostic work-up together with an outcome during the follow up. Methods: This was a retrospective, single center, observational study including all patients who were diagnosed with FGID based on Rome III criteria from January to December 2015 in tertiary medical center. Results: Overall 294 children were included (mean age, 8.9 years [range, 1-18 years]; 165 females). Majority had functional constipation (35.4%), followed by functional abdominal pain (30.6%), irritable bowel syndrome (17.0%), functional dyspepsia (12.6%), functional nausea (3.4%) and abdominal migraine (1.0%). Regression model found that only significant factor associated with improvement of symptoms is the establishment of the functional diagnosis at the first visit (hazard ratio, 2.163; 95% confidence inverval, 1.029-4.544). There was no association between improvement of symptoms and presence of alarm signs/symptoms (weight loss, nocturnal symptoms and severe vomiting) at diagnosis. Furthermore, in pain symptoms (functional abdominal pain, irritable bowel syndrome, dyspepsia) no treatment positively correlated with pain improvement. Conclusion: Regardless of the initial diagnosis of FGID, positive diagnosis at the first visit increases a chance for resolution of symptoms.

Roles of Ethnicity in Survival of Hepatocellular Carcinoma Patients in Malaysia

  • Azmawati, M.N.;Krisnan, R.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6023-6026
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    • 2012
  • The incidence of hepatocellular carcinoma (HCC) in Malaysia for the year 2001 was 2.8 per 100,000 people. The mortality rate is increasing. A retrospective cohort study measuring the survival of HCC patients who received treatment in Selayang Hospital was conducted from 1 January 2003 to 31 December 2006. The main objectives of the study were to measure the survival of the patients and to understand the influencing factors, especially ethnicity. The subjects were newly diagnosed cases of HCC by CT scan and histopathological assessment who underwent futher investigations and treatments in Hospital Selayang (inception cohort). The survival time was measured from the date of diagnosis until the subjects died, or failed to follow-up at the end of the study period (31 December 2007). A total of 299 patients were selected with 95 patients dying, the majority among Chinese (39.1%). Subgroup analysis according to ethnicity proved significantly that Chinese patients who had smaller tumor, less number of nodules, low AFP level, Child Pugh Class A and received surgical treatment had a better median survival rate compared to other ethnic groups. Malay (cHR: 1.3, 95%CI; 0.89-1.85) and Indian (cHR: 1.3, 95%CI; 0.74-2.26) patients had a poor survival compared to Chinese patients, but not in the final model. Therefore ethnicity may play a role in survival of HCC patients, but not as a main hazard prognostic factor.