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Derivation of Inherent Optical Properties Based on Deep Neural Network (심층신경망 기반의 해수 고유광특성 도출)

  • Hyeong-Tak Lee;Hey-Min Choi;Min-Kyu Kim;Suk Yoon;Kwang-Seok Kim;Jeong-Eon Moon;Hee-Jeong Han;Young-Je Park
    • Korean Journal of Remote Sensing
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    • v.39 no.5_1
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    • pp.695-713
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    • 2023
  • In coastal waters, phytoplankton,suspended particulate matter, and dissolved organic matter intricately and nonlinearly alter the reflectivity of seawater. Neural network technology, which has been rapidly advancing recently, offers the advantage of effectively representing complex nonlinear relationships. In previous studies, a three-stage neural network was constructed to extract the inherent optical properties of each component. However, this study proposes an algorithm that directly employs a deep neural network. The dataset used in this study consists of synthetic data provided by the International Ocean Color Coordination Group, with the input data comprising above-surface remote-sensing reflectance at nine different wavelengths. We derived inherent optical properties using this dataset based on a deep neural network. To evaluate performance, we compared it with a quasi-analytical algorithm and analyzed the impact of log transformation on the performance of the deep neural network algorithm in relation to data distribution. As a result, we found that the deep neural network algorithm accurately estimated the inherent optical properties except for the absorption coefficient of suspended particulate matter (R2 greater than or equal to 0.9) and successfully separated the sum of the absorption coefficient of suspended particulate matter and dissolved organic matter into the absorption coefficient of suspended particulate matter and dissolved organic matter, respectively. We also observed that the algorithm, when directly applied without log transformation of the data, showed little difference in performance. To effectively apply the findings of this study to ocean color data processing, further research is needed to perform learning using field data and additional datasets from various marine regions, compare and analyze empirical and semi-analytical methods, and appropriately assess the strengths and weaknesses of each algorithm.

Analyze Technologies and Trends in Commercialized Radiology Artificial Intelligence Medical Device (상용화된 영상의학 인공지능 의료기기의 기술 및 동향 분석)

  • Chang-Hwa Han
    • Journal of the Korean Society of Radiology
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    • v.17 no.6
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    • pp.881-887
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    • 2023
  • This study aims to analyze the development and current trends of AI-based medical imaging devices commercialized in South Korea. As of September 30, 2023, there were a total of 186 AI-based medical devices licensed, certified, and reported to the Korean Ministry of Food and Drug Safety, of which 138 were related to imaging. The study comprehensively examined the yearly approval trends, equipment types, application areas, and key functions from 2018 to 2023. The study found that the number of AI medical devices started from four products in 2018 and grew steadily until 2023, with a sharp increase after 2020. This can be attributed to the interaction between the advancement of AI technology and the increasing demand in the medical field. By equipment, AI medical devices were developed in the order of CT, X-ray, and MR, which reflects the characteristics and clinical importance of the images of each equipment. This study found that the development of AI medical devices for specific areas such as the thorax, cranial nerves, and musculoskeletal system is active, and the main functions are medical image analysis, detection and diagnosis assistance, and image transmission. These results suggest that AI's pattern recognition and data analysis capabilities are playing an important role in the medical imaging field. In addition, this study examined the number of Korean products that have received international certifications, particularly the US FDA and European CE. The results show that many products have been certified by both organizations, indicating that Korean AI medical devices are in line with international standards and are competitive in the global market. By analyzing the impact of AI technology on medical imaging and its potential for development, this study provides important implications for future research and development directions. However, challenges such as regulatory aspects, data quality and accessibility, and clinical validity are also pointed out, requiring continued research and improvement on these issues.

A Study on the Countermeasures Taken By the Korean Healthcare and Life Sciences Industry Regarding U.S. Import Refusals: Focus on the Analysis of FDA Violation Codes (한국 바이오헬스 산업의 미국 수입거부 대응 방안 연구 : FDA 위반코드 분석을 중심으로)

  • Yu-Han Lee;Hag-Min Kim
    • Korea Trade Review
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    • v.48 no.3
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    • pp.131-150
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    • 2023
  • The purpose of this study was to find a countermeasure to the U.S. import refusals for the Korean healthcare and life sciences industry. To this end, an analysis of trends during the pandemic was conducted using the KITA Border Rejection Database, which includes information on items and types of import refusals. The reason for rejection was also analyzed according to the FDA violation codes. The degree of countermeasure for import refusals was identified by measuring the unit rejection rate (URR). The results of the analysis showed that the major U.S. import refusals for the Korean healthcare and life sciences industry had expanded from contact lenses to COVID-19 diagnostic kits and drugs after the pandemic broke out. The major reasons for import refusals were non-compliance with the Predicate Device and Drugs Act and non-approval by the FDA for products and facilities. On the other hand, the unit rejection rate (URR) of major items in the Korean healthcare and life sciences industry was measured higher than the industry average. The results therefore showed a low level of response to U.S. import refusals. The results of the analysis of reasons for import refusals by item according to FDA violation codes were as follows. First of all, the main violation for contact lenses and COVID-19 diagnostic kits corresponded to misbranding. This was often due to the fact that Korean companies did not provide the relevant notices and information required by the FDA. Many cases also failed to demonstrate a substantial equivalency compared to predicate devices already on the market. On the other hand, applications for new unapproved drugs were not accepted as they had yet to pass relevant regulations that would prove their safety and efficacy. In conclusion, import refusals for the Korean healthcare and life sciences industry were found to be closely related to technical barriers to trade (TBT).

A survey on status of quality and risk assessment in dentifrices and mouthwashes (치약제 및 구중청량제의 품질 실태 조사 및 안전성 평가)

  • Jaeeun Kwak;Wonhee Park;Hoejin Ryu;Jin Han;Jeongeun Choe;Sungdan Kim;Insook Hwang;Yongseung Shin
    • Analytical Science and Technology
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    • v.36 no.6
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    • pp.300-314
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    • 2023
  • The quality of the products was investigated by analyzing fluorine content, pH, preservatives and tar colors in 31 dentifrice products (6 items for children) and 15 mouthwash products (2 items for children) marketed. It was intended to provide correct information to consumers by checking whether the standards and product indications match. As a result of measuring the fluoride concentration, 26 dentifrice and 15 mouthwash products contained from 48 to 1,472 ppm and from 85 to 225 ppm, respectively. Fluorine detection rates of dentifrice and mouthwash products were 83.9 and 83.3 %, respectively showing similar levels. Of the 41 fluoride-detected dentifrice and mouthwash products, 40 were 90.7~109.8 % of the displayed amount and suitable for the fluorine content standard of 90.0 to 110.0 %, but one dentifrice was found to be inappropriate at 36.3 % of the content indicated on the product. The pH of the dentifrice was 5.1~9.4, and the mouthwash was 4.2~6.2, which met all standards. As a result of simultaneous analysis of the concentration of six preservatives, benzoic acid was detected the most in 15 cases with a 30.6 % detection rate, sorbic acid was detected in 9 cases (detection rate of 18.4 %), and all four types of methyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate were not detected. As a result of analyzing the concentration of 10 types of tar colors, six types including red40, yellow4, yellow5, yellow203, green3, and blue1 were detected in a total of 9 cases (2 dentifrices and 7 mouthwashes) with blue1 being the most frequently detected. Detected fluorine concentration, added preservatives and tar colors were consistent with the product markings and it was well written on product packaging. The detected preservatives and tar colors were at a safe level due to low risk compared to Acceptable Daily Intake.

The content and risk assessment of heavy metals in commercial herbal medicines (서울지역 유통한약재의 중금속 함량 및 위해성 평가)

  • Young Shin;Sang-Hun Park;Seung-Hye Han;So-Hyun Park;Ji-Hye Kim;Hyun-Jung Jang;Ae-Kyoung Kim;Ju-Seung Park
    • Analytical Science and Technology
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    • v.36 no.6
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    • pp.267-280
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    • 2023
  • This study investigated the contents of Pb, Cd, As, and Hg for 4333 samples with 2 09 types of herbal medicines distributed in Seoul area from 2019 to 2021, and evaluated risk assessment according to medicinal part used and origin. The contents of heavy metals were analyzed by inductively coupled plasma mass spectrometry (ICP-MS) and mercury analyzer. The average contents (mg/kg) of heavy metals by medicinal parts were 0.123 to 1.290 for Pb, 0.018 to 0.131 for Cd, 0.034 to 0.290 for As, and 0.003 to 0.015 for Hg. The contents of Pb were higher in Leaves and Whole Herbs (above-ground part) than underground part (Radix & Rhizoma) (ANOVA-test, p < 0.05). The contents of Cd were high in Leaves, Radix & Rhizoma, and Stems & Woods (ANOVA-test, p <0 .05), and exceeded regulatory limits in various types. Levels of Pb, Cd concentrations exceeding regulatory limits were observed in 8, 22 samples (8, 14 types). No sample exceeded regulatory limits of As and Hg. In the comparison between countries of origin, the contents of Cd, As, and Hg were high in imported herbal medicines (t-test, p < 0.05). As a result of the risk assessment, except for Thujae Orientalis Folium and Spirodelae Herba, the MOE values of Pb were all 1 or more, and most samples were safe. The Hazard Index (HI) for Cd, As, and Hg were evaluated to be less than 100 % even if the risk (%) of each heavy metal was added, and the risk from taking herbal medicines was evaluated to be safe.

A study of analytical method for Benzo[a]pyrene in edible oils (식용유지 중 벤조피렌 분석법 비교 연구)

  • Min-Jeong Kim;jun-Young Park;Min-Ju Kim;Eun-Young Jo;Mi-Young Park;Nan-Sook Han;Sook-Nam Hwang
    • Analytical Science and Technology
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    • v.36 no.6
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    • pp.291-299
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    • 2023
  • The benzo[a]pyrene in edible oils is extracted using methods such as Liquid-liquid, soxhlet and ultrasound-assisted extraction. However these extraction methods have significant drawbacks, such as long extraction time and large amount of solvent usage. To overcome these drawbacks, this study attempted to improve the current complex benzo[a]pyrene analysis method by applying the QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method that can be analyzed in a simple and short time. The QuEChERS method applied in this study includes extraction of benzo[a]pyrene into n-hexane saturated acetonitrile and n-hexane. After extraction and distribution using magnesium sulfate and sodium chloride, benzo[a]pyrene is analyzed by liquid chromatography with fluorescence detector (LC/FLR). As a result of method validation of the new method, the limit of detection (LOD) and quantification (LOQ) were 0.02 ㎍/kg and 0.05 ㎍/kg, respectively. The calibration curves were constructed using five levels (0.1~10 ㎍/kg) and coefficient (R2) was above 0.99. Mean recovery ratio was ranged from 74.5 to 79.3 % with a relative standard deviation (RSD) between 0.52 to 1.58 %. The accuracy and precision were 72.6~79.4 % and 0.14~7.20 %, respectively. All results satisfied the criteria ranges requested in the Food Safety Evaluation Department guidelines (2016) and AOAC official method of analysis (2023). Therefore, the analysis method presented in this study was a relatively simple pretreatment method compared to the existing analysis method, which reduced the analysis time and solvent use to 92 % and 96 %, respectively.

Changes in Soil Physiochemcial Properties Over 11 Years in Larix kaempferi Stands Planted in Larix kaempferi and Pinus rigida Clear-Cut Sites (낙엽송과 리기다소나무 벌채지에 조성된 낙엽송 임분의 11년간 토양 물리·화학적 특성 변화)

  • Nam Jin Noh;Seung-hyun Han;Sang-tae Lee;Min Seok Cho
    • Journal of Korean Society of Forest Science
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    • v.112 no.4
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    • pp.502-514
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    • 2023
  • This study was conducted to understand the long-term changes in soil physiochemical properties and seedling growth in Larix kaempferi (larch) stands planted in clear-cut larch and Pinus rigida (pine) forest soils over an 11-year period after reforestation. Two-year-old bare-root larch seedlings were planted in 2009-2010 at a density of 3,000 seedlings ha-1 in clear-cut areas that harvested larch (Chuncheon and Gimcheon) and pine (Wonju and Gapyeong) stands. We analyzed the physiochemical properties of the mineral soils sampled at 0-20 cm soil depths in the planting year, and the 3rd, 7thand 11th years after planting, and we measured seedling height and root collar diameter in those years. We found significant differences in soil silt and clay content, total carbon and nitrogen concentration, available phosphorus, and cation exchangeable capacity between the two stands; however, seedling growth did not differ. The mineral soil was more fertile in Gimcheon than in the other plantations, while early seedling growth was greatest in Gapyeong. The seedling height and diameter at 11 years after planting were largest in Wonju (1,028 tree ha-1) and Chuncheon (1,359 tree ha-1) due to decreases in stand density after tending the young trees. The soil properties in all plantations were similar 11 years after larch planting. In particular, the high sand content and high available phosphorus levels (caused by soil disturbance during clear-cutting and planting) showed marked decreases, potentially due to soil organic matter input and nutrient uptake, respectively. Thus, early reforestation after clear-cutting could limit nutrient leaching and contribute to soil stabilization. These results provide useful information for nutrient management of larch plantations.

Estimating Optimal Timber Production for the Economic and Public Functions of the National Forests in South Korea (국유림의 경제적·공익적 기능을 고려한 적정 목재생산량 추정)

  • Yujin Jeong;Younghwan Kim;Yoonseong Chang;Dooahn Kwak;Gihyun Park;Dayoung Kim;Hyungsik Jeong;Hee Han
    • Journal of Korean Society of Forest Science
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    • v.112 no.4
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    • pp.561-573
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    • 2023
  • National forests have an advantage over private forests in terms of higher investment in capital, technology, and labor, allowing for more intensive management. As such, national forests are expected to serve not only as a strategic reserve of forest resources to address the long-term demand for timber but also to stably perform various essential forest functions demanded by society. However, most forest stands in the current national forests belong to the fourth age class or above, indicating an imminent timber harvesting period amid an imbalanced age class structure. Therefore, if timber harvesting is not conducted based on systematic management planning, it will become difficult to ensure the continuity of the national forests' diverse functions. This study was conducted to determine the optimal volume of timber production in the national forests to improve the age-class structure while sustainably maintaining their economic and public functions. To achieve this, the study first identified areas within the national forests suitable for timber production. Subsequently, a forest management planning model was developed using multi-objective linear programming, taking into account both the national forests' economic role and their public benefits. The findings suggest that approximately 488,000 hectares within the national forests are suitable for timber production. By focusing on management of these areas, it is possible to not only improve the age-class distribution but also to sustainably uphold the forests' public benefits. Furthermore, the potential volume of timber production from the national forests for the next 100 years would be around 2 million m3 per year, constituting about 44% of the annual domestic timber supply.

Improvement of Mid-Wave Infrared Image Visibility Using Edge Information of KOMPSAT-3A Panchromatic Image (KOMPSAT-3A 전정색 영상의 윤곽 정보를 이용한 중적외선 영상 시인성 개선)

  • Jinmin Lee;Taeheon Kim;Hanul Kim;Hongtak Lee;Youkyung Han
    • Korean Journal of Remote Sensing
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    • v.39 no.6_1
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    • pp.1283-1297
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    • 2023
  • Mid-wave infrared (MWIR) imagery, due to its ability to capture the temperature of land cover and objects, serves as a crucial data source in various fields including environmental monitoring and defense. The KOMPSAT-3A satellite acquires MWIR imagery with high spatial resolution compared to other satellites. However, the limited spatial resolution of MWIR imagery, in comparison to electro-optical (EO) imagery, constrains the optimal utilization of the KOMPSAT-3A data. This study aims to create a highly visible MWIR fusion image by leveraging the edge information from the KOMPSAT-3A panchromatic (PAN) image. Preprocessing is implemented to mitigate the relative geometric errors between the PAN and MWIR images. Subsequently, we employ a pre-trained pixel difference network (PiDiNet), a deep learning-based edge information extraction technique, to extract the boundaries of objects from the preprocessed PAN images. The MWIR fusion imagery is then generated by emphasizing the brightness value corresponding to the edge information of the PAN image. To evaluate the proposed method, the MWIR fusion images were generated in three different sites. As a result, the boundaries of terrain and objects in the MWIR fusion images were emphasized to provide detailed thermal information of the interest area. Especially, the MWIR fusion image provided the thermal information of objects such as airplanes and ships which are hard to detect in the original MWIR images. This study demonstrated that the proposed method could generate a single image that combines visible details from an EO image and thermal information from an MWIR image, which contributes to increasing the usage of MWIR imagery.

Performance Evaluation of Monitoring System for Sargassum horneri Using GOCI-II: Focusing on the Results of Removing False Detection in the Yellow Sea and East China Sea (GOCI-II 기반 괭생이모자반 모니터링 시스템 성능 평가: 황해 및 동중국해 해역 오탐지 제거 결과를 중심으로)

  • Han-bit Lee;Ju-Eun Kim;Moon-Seon Kim;Dong-Su Kim;Seung-Hwan Min;Tae-Ho Kim
    • Korean Journal of Remote Sensing
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    • v.39 no.6_2
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    • pp.1615-1633
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    • 2023
  • Sargassum horneri is one of the floating algae in the sea, which breeds in large quantities in the Yellow Sea and East China Sea and then flows into the coast of Republic of Korea, causing various problems such as destroying the environment and damaging fish farms. In order to effectively prevent damage and preserve the coastal environment, the development of Sargassum horneri detection algorithms using satellite-based remote sensing technology has been actively developed. However, incorrect detection information causes an increase in the moving distance of ships collecting Sargassum horneri and confusion in the response of related local governments or institutions,so it is very important to minimize false detections when producing Sargassum horneri spatial information. This study applied technology to automatically remove false detection results using the GOCI-II-based Sargassum horneri detection algorithm of the National Ocean Satellite Center (NOSC) of the Korea Hydrographic and Oceanography Agency (KHOA). Based on the results of analyzing the causes of major false detection results, it includes a process of removing linear and sporadic false detections and green algae that occurs in large quantities along the coast of China in spring and summer by considering them as false detections. The technology to automatically remove false detection was applied to the dates when Sargassum horneri occurred from February 24 to June 25, 2022. Visual assessment results were generated using mid-resolution satellite images, qualitative and quantitative evaluations were performed. Linear false detection results were completely removed, and most of the sporadic and green algae false detection results that affected the distribution were removed. Even after the automatic false detection removal process, it was possible to confirm the distribution area of Sargassum horneri compared to the visual assessment results, and the accuracy and precision calculated using the binary classification model averaged 97.73% and 95.4%, respectively. Recall value was very low at 29.03%, which is presumed to be due to the effect of Sargassum horneri movement due to the observation time discrepancy between GOCI-II and mid-resolution satellite images, differences in spatial resolution, location deviation by orthocorrection, and cloud masking. The results of this study's removal of false detections of Sargassum horneri can determine the spatial distribution status in near real-time, but there are limitations in accurately estimating biomass. Therefore, continuous research on upgrading the Sargassum horneri monitoring system must be conducted to use it as data for establishing future Sargassum horneri response plans.