• Journal of Environmental Health Sciences
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• v.18 no.2
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• pp.135-145
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• 1992

This study was carried out to find out some characteristic responses of biological samples under the exposure of trace metals with the considering of Sex, age, residence period and smoking. Blood, Urine and Hair were collected from 116 dwellers in the vicinity of a smelting factory. Cd, Cu, Pb and Zn concentrations were determined by flame atomic absorption spectrophotometry and the following results were found important. 1) The concentrations of trace metals in the blood were 0.010+ 0.003 $\mu$g/ml in Cd, 0.82+ 0.11 $\mu$g/ml in Cu, 0.23_+ 0.13 $\mu$g/ml in Pb and 5.78_+ 1.43 $\mu$g/ml in Zn, those in the urine were 1.7_+ 1.7 $\mu$g/l in Cd, 16.5_+ 16.0 $\mu$g/l in Cu, 24.6_+ 23.0 $\mu$g/l in Pb and 367.7_+ 283.4 $\mu$g/l in Zn, and those in the hair were 0.52_+ 0.56 $\mu$g/g in Cd, 11.00_+4.01 $\mu$g/g in Cu, 8.53_+ 7.05 $\mu$g/g in Pb and 383.23_+ 110.56 $\mu$g/g in Zn. 2) In sex, the concentrations of Zn in the blood and urine of male were higher than those of female, however, the concentrations of Cd and Zn in the hair of female were higher than those of male. 3) The concentrations of Cd, Pb and Zn in the urine showed an increasing trend by age. 4) While the concentration of Cd in the urine increased, the concentration of Pb in the hair decreased by residential period in all the samples. 5) The concentrations of Cd and Zn in the blood and that of Zn in the urine of smoking group were higher than those of non-smoking group. The concentration of Pb in the blood of smoking group and those of Cd, Pb and Zn in the urine of non-smoking group showed increasing the trend by age. The concentrations of Cd and Zn in the urine of non-smoking group, the concentration of Zn in the hair of smoking group showed increasing trend by residential period, however, the concentrations of Pb in the blood and hair and that of Zn in the hair showed decreasing trend by residential period. 6) When the correlations of the concentrations between Zn (main smelting metal) and other metals were analyzed, Zn in the blood was significantly correlated with Cu, Pb and Zn in the urine (positively) and Zn in the urine was significantly correlated with Zn in the blood, Cd, Cu and Pb in the urine, and Pb in the hair (positively). Zn in the hair was significantly correlated with Cd in the urine and Cu in the hair (positively). 7) Consequently, it was useful to note that samples of urine showed higher sensitivity under the metal exposure than those of blood and hair in individual sampling. In addition, as trace metals showed higher accumulation in the hair of the groups, sampling of hair was more highly recommended than those of urine and blood in group sampling.

• Journal of environmental and Sanitary engineering
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• v.19 no.4 s.54
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• pp.61-68
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• 2004

Hair driers and chemicals used in beauty shops generate a number of heavy metals and $PM_{10}$. Also many $PM_{10}$ are produced during hair cut. The pollutions raised health problems and uncomfortableness to hair dressers and customers in beauty shops. This study investigated to assess indoor, outdoor and personal particulate pollutants ($PM_{10}$ and Heavy metals) mean concentrations and the source of the pollutants in beauty shops. The results are summarized as follows: 1. The measured mean concentrations of respiratory particulates were $30.5ng/m^2$ in indoor, $30.5ng/m^2$ in outdoor and$44.0ng/m^2$ on personal levels. The personal concentration was found higher than indoor and outdoor concentrations. 2. The heavy metals mean concentrations were showed as indoor (Na>Zn>Cr), outdoor (Cr>Zn>Pb), and personal (Na>Cr>Zn) levels. 3. Chemicals and hair driers were regarded as the major sources of the pollutions. 4. Na was correlated with Mg, Zn and Cd, while Mg was correlated with Ni. Mn was correlated with Cu, Zn and AS, where as Cu was correlated with Zn, As and Cd. Zn and As, and Asand Cd were correlated each other. Na was inversely correlated with Cr.

• Advances in Traditional Medicine
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• v.10 no.3
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• pp.141-149
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• 2010

A concern of safety issue for traditional herbal medicine is the possibility of some herbs containing heavy metals responsible for several cases of metal poisoning. In our previous study, the physiological levels of heavy metals, such as Cd, Cu, Hg and Pb, were examined to evaluate a potential risk in patients taking herbal medicine. In this study, the levels of 12 heavy metals, including non-metallic element, Se, were analyzed in hair and compared to the results from the previous study. In the previous study, the levels of Cd, Cu, Hg and Pb in hair showed a significantly lower odds ratio than 1. In this study, however, all metals did not show any significant odds ratio higher or lower than 1 even if 5 of 12 metals showed lower odds ratio than 1. In addition, the levels of metal concentrations, especially for Cu, Fe, Pb and Zn, exceeding the WHO reference values were observed in hair. However, any evidence for metal accumulation in hair caused by taking herbal medicines for long duration was not observed in analysis of multiple regression and odds ratio from case-control study. This result would show another possibility for a role of herbs as a non-enzymatic chelator inhibiting the gastrointestinal absorption of heavy metals.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.7 no.2
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• pp.233-244
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• 1997

In order to investigate the concentration of trace metals in human hairs from residents living in urban area and rural area, the 120 hair samples of adults were taken from urban areas(industrial area, bus terminal, downtown area) and rural area(Kasan-ri, Yeoju-up, Yeoju-goon) during July - September 1995. Mean concentrations of trace metals including lead and cadmium in human hair were compared by region, sex, presence of smoker, type of water, period of residence. The results were as follows; 1. The average concentrations of lead and cadmium in hairs of urban area are $0.92{\mu}g/g$ ($1.01{\mu}g/g$ industrial area, $1.01{\mu}g/g$ bus terminal, $0.74{\mu}g/g$ downtown area), $0.38{\mu}g/g$ ($0.54{\mu}g/g$ industrial area, $0.49{\mu}g/g$ bus terminal, $0.12{\mu}g/g$ downtown area). The mean concentrations of lead and cadmium in urban area are higher than the corresponding levels in the rural area. 2. Lead concentration for male in the urban and rural area is 0.94 and $0.62{\mu}g/g$, 0.90 and $0.60{\mu}g/g$ for female. But, It does not have any statistical significance. Cadmium concentration for male in the urban and rural area is 0.38 and $0.12{\mu}g/g$, 0.38 and $0.11{\mu}g/g$ for female. But It does not have any statistical significance. 3. Mean concentrations of lead and cadmium in smokers shows higher than non-smokers. It showed that the longer period of residence in urban area, the higher concentrations of three metals.

• Journal of environmental and Sanitary engineering
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• v.3 no.1 s.4
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• pp.75-85
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• 1988

An atomic absorption spectrophotometry analysis study of zinc, cadimium, lead, copper and mercury in human scalp hair samples of 699 subjects in 3 urban and 4 rural communities gave mean values of 170.33/187.00 ppm, 0.18/0.22 ppm, 8.43/8.62 ppm, 9.81/10.24 ppm and 2.13/1.20 ppm for male and female, respectively. The concentration did not differ significantly regardless ages. However, female was higher than male in overall concentration except that of mercury. The percentile methods was partially applied for a reference values of metals in Korean scalp hair to provide more appropriate data for further comparisons.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.23 no.2
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• pp.63-68
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• 2012

Objectives : The purpose of this study was to examine the association of exposures to heavy metals with positive diagnosis for attention-deficit hyperactivity disorder (ADHD) and Tourette's syndrome (TS). Methods : Study participants included 27 children diagnosed with ADHD ($9.9{\pm}2.9$ years of age), 21 diagnosed with Tourette's disorder ($10.7{\pm}2.2$ years of age), and 45 normal control children ($9.6{\pm}0.5$ years of age). A Perkin-Elmer mass spectrometer was used to measure the concentrations of 5 heavy metals (Pb, Cd, U, Be, Hg) in hair samples obtained from each participant. Each heavy metal concentration was compared among the groups by use of a Kruskal-Wallis test. Results : The levels of lead (p=.006) and cadmium (p=.037) observed in the hair of children diagnosed with ADHD were significantly higher than those found in the control subjects. There were no significant differences observed for heavy metal levels when comparing TS and control subjects. Conclusion : We confirmed that lead exposure is a risk factor for ADHD. We also identified that cadmium may be a new candidate risk factor for manifestation of ADHD. We did not find an association between heavy metals and manifestation of TS.

• Journal of Digital Convergence
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• v.15 no.10
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• pp.551-557
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• 2017

Hair beauty treatments that can express individuality have increased and diversified. However, their repetitive use has also brought about hair damage. To reduce such damage, the importance of hair treatments when receiving chemotherapy has magnified greatly. In this study, the hair (normal hair, NH) of 5 people in their 20s has been collected and observed with SEM before dyeing (NH), after dyeing (DH) and after dyed and treated (DTH) to measure the hair's morphological damage and mineral content. SEM observation results revealed that, in DTH, a cuticle-like arrangement appears almost uniformly, the hair settles, the lines are smooth, and the damage degree is low. Regarding mineral content, the concentration of minerals was generally balanced. However, in the observation of toxic minerals and minerals found in large amounts, the concentration of Ba, Na, Ca, and Mg was higher than the balance range in NH, DH, and DTH.

• Journal of Society of Preventive Korean Medicine
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• v.6 no.1
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• pp.129-139
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• 2002

This research purpose was to get urine and hair metal correlation by Spearman methods in subjects with long term intake of herbal medicine. And that result can help research for metal absorption mechanism in body. Subjects have been intake 1-124 months(7.55 months mean) in decoction and 1-60 months (1.27 months means) for some disease treatment in sampling point. 1) Metal concentrations in urine and hair of study subjects showed higher than WHO reference limits, especially 0.32-6.17% in urine and 11.69-26.95% in hair. 2) Metal concentration in urine correlated 0.37(p〈0.001) Cu to Cd, 0.37(p〈0.001) Pb to Cu, 0.29(p〈0.001) Pb to Cu, 0.29(p〈0.001) Pb to Cd, and 0.36(p〈0.001) Pb to Cu, -0.13(p〈0.05) Hg to Cu in hair. Also between urine and hair correlated 0.21(p〈0.001) Cd to Cd. 0.17(p〈0.01) Pb to Pb, -0.06 Cu to Hg, -0.01 Hg to Cu. These results showed that occur physical and chemical reaction among many metals in body, respectively. However, further study related this subjects will be need.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.35 no.1
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• pp.27-32
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• 2009

Human hair is an excretory system for trace metals and thus metal content in human hair can reflect the body status. The investigation of trace elements in human hair has been correlated with the diagnosis of various diseases as well as the monitoring of deficiency statues in nutrition. Many chronic diseases may be related to mineral status, some may be related to toxic mineral. Hair samples were collected from 120 inhabitants of the city of Seoul, Korea. In this study the concentrations of 10 elements (Hg, Pb, Cd, Al, As, U, Bi, Sb, Ba, Be) in hair were determined by inductively coupled plasma mass spectroscopy (ICP-MS). The conclusions showed that people in Seoul, Korea were affected by some kinds of toxic minerals. The Hg concentrations of male are higher than those of female and reference range. The mean concentration of Sb was higher in the female than male and reference range. In age distribution, the mean concentration of Hg was in 40's are higher than 20's and 30's and reference range. The concentrations of Al were the highest in the 20's. After analyzing, we concluded that a compounded treatment should be conducted, which considers the variety of factors related to detoxification.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.39 no.3
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• pp.241-249
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• 2013

This study was aimed to provide the fundamental data about oxidized hair color products. For this reason, we collected 125 oxidized hair color products, which were distributed in domestic market from January to October, 2012, and measured the heavy metal concentrations of lead, arsenic, cadmium, chromium, manganese, nickel, copper in the samples. Results were compared by domestic, foreign, henna, type and color. The average metal concentrations were as follows; 0.211 ${\mu}g/g$ for lead, 0.008 ${\mu}g/g$ for cadmium, 0.051 ${\mu}g/g$ for arsenic, 0.954 ${\mu}g/g$ for chromium, 6.250 ${\mu}g/g$ for manganese, 0.591 ${\mu}g/g$ for nickel and 0.544 ${\mu}g/g$ for copper. In case of lead and arsenic, the concentrations were much less than the regulated amount (20 ${\mu}g/g$ and 10 ${\mu}g/g$, respectively) suggested by MFDS (Ministry of Food and Drug Safety). In henna (p < 0.05), the concentrations were significantly higher than those of other domestic and foreign oxidized hair color products as follows; 1.264 ${\mu}g/g$ for lead, 0.267 ${\mu}g/g$ for arsenic, 0.025 ${\mu}g/g$ for cadmium, 4.055 ${\mu}g/g$ for chromium, 72.044 ${\mu}g/g$ for manganese, 3.076 ${\mu}g/g$ for nickel and 4.640 ${\mu}g/g$ for copper. Statistically, it showed that the heavy metal concentrations were quite different for the different types of hair color products. The cream and liquid type products had the highest average concentration in chromium (0.708 ${\mu}g/g$, 0.478 ${\mu}g/g$, respectively). On the other hand, powder type products showed the highest concentration in manganese (60.041 ${\mu}g/g$). In addition, the concentrations of heavy metals and the color of products are not quite correlated. It was shown that average concentrations of lead and chromium were higher for yellow, chromium for red and pink, manganese for brown and black, and nickel for green.