• Korean Journal of Plant Resources
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• v.28 no.5
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• pp.582-590
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• 2015

In the present study, we investigated the effect of 70% EtOH extract from Hippophae Rhamnoides L. leaves (HRL) on the anti-obesity effect in 3T3-L1 cells. The effects of HRL on lipid accumulation in 3T3-L1 cells were examined using Oil Red O staining. In addition, we examined the gene expression levels by using RT-PCR and western blot. The results of this analysis showed that 100 ㎍/㎖ HRL significantly increased the inhibition of lipid accumulation by 82.25%; significantly decreased the mRNA expression of sterol regulatory element binding protein-1c (SREBP-1c), peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding proteins α (C/EBPα), and fatty acid synthase (FAS) in 3T3-L1 cells as well as the stimulated protein expression of AMP-activated protein kinase (AMPK); and suppressed the expression level of PPARγ. These results suggest that HRL can prevent adipogenesis through activation of AMPKα and inhibition of adipogenesis transcription factors.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.268-271
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• 2005

COMS (Communication, Ocean, and Meteorological Satellite) will be launch at end of year 2008. For receiving of COMS LRlT, KARl (Korea Aerospace Research Institute) finished design and software realization of COMS SDUS (Small Data Utilization System). SDUS is a small station receiving LRlT data for distribute satellite image, weather information, and so on. For the future project, KARl preparing COMS MDUS (Mass Data Utilization System) that can receiving large size of data over than 2M BPS (Bit Per Seconds) data size.