• Hip & pelvis
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• 제34권3호
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• pp.150-160
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• 2022

Purpose: The purpose of this study is to determine risk factors that affect mortality following osteoporotic hip fracture in patients 50 years or older using the National Health Insurance Service (NHIS) sample cohort 2.0 database. Materials and Methods: Data from 2,533 patients who satisfied the inclusion criteria for the NHIS sample cohort 2.0 database were used in this study. Data from patients who suffered osteoporotic hip fractures between 2002-2015 were used. An analysis of correlations between the incidence of osteoporotic hip fractures and various factors (sex, age, underlying diseases, etc.) was performed. Analysis of the associations between the mortality of osteoporotic hip fracture and the various factors with hazard ratio (HR) was performed using Cox regression models. Results: Patient observation continued for an average of 38.12±32.09 months. During the observation period, a higher incidence of hip fracture was observed in women; however, higher mortality following the fracture was observed in men (HR=0.728; 95% confidence interval [CI], 0.635-0.836). The incidence and mortality of fractures increased when there were increasing age, more than three underlying diseases (HR=1.945; 95% CI, 1.284-2.945), cerebrovascular diseases (HR=1.429; 95% CI, 1.232-1.657), and renal diseases (HR=1.248; 95% CI, 1.040-1.497). Also, higher mortality was observed in patients who were underweight (HR=1.342; 95% CI, 1.079-1.669), current smokers (HR=1.338; 95% CI, 1.104-1.621), and inactivity (HR=1.379; 95% CI, 1.189-1.601). Conclusion: Male gender, the presence of cerebrovascular or kidney disease, a more than three underlying diseases, underweight, a current smoker, and inactivity were risk factors that increased mortality.

• 한국수자원학회논문집
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• 제32권4호
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• pp.457-467
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• 1999

유역의 토양유실량을 정확하게 추정하는 방법은 아직 없으며 현재로서 가장 바람직한 유사한 지역의 토양유실량 실측자료를 이용하는 것이다. 이러한 실측자료가 없는 경우에는 범용토양유실공식(USLE, Universal Soil Loss Equation)과 같이 경험적으로 토양유실량을 추정하는 방법 등을 이용할 수 있다. 범용토양유실공식의 인자 중 지역의 수문 특성에 지배되는 되는 것으로 강우침식도(rainfall erosivity) {{{{{ R}_{}}}}} 이 있다. 본 연구에서는 지속기간 0.5, 1, 2, 3, 6, 12, 24-hr에 대한 재현기간 2, 5, 10, 20, 30, 50, 80, 100, 150, 200, 500-yr의 확률강우량을 구하였고 이를 이용하여 빈도별 지속기간 24-hr 설계호우의 지점별 {{{{ { R}_{ } }}}} 값을 구하였다. 지점별{{{{ { R}_{ } }}}} 값을 내삽하여 우리 나라 전역의 등{{{{ { R}_{ } }}}}선도를 작성하였다. 본 연구에서 구해진 재현기간 5-yr, 지속기간 24-hr 설계호우의 등{{{{ { R}_{ } }}}}선도는 연평균 등{{{{ { R}_{ } }}}}선도와 매우 유사하였고, 임의 재현기간에 해당하는 {{{{ { R}_{ } }}}}값은 재현기간 5-yr 또는 연평균{{{{ { R}_{ } }}}}값에 적절한 배율을 곱하여 추정할 수 있음을 알 수 있었다. 본 연구에서 구해진 재현기간별 지속시간 24-hr 설계호우의 등{{{{{R}_{}}}}} 선도는 침사지 등의 설계에 유용하게 이용될 수 있을 것으로 판단된다.

• 대한두경부종양학회지
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• 제37권2호
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• pp.19-24
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• 2021

Background/Objectives: The aim of this national population-based retrospective study was to analyze the status and treatment outcome in patients with hypopharyngeal cancer. Materials & Methods: Participants were included in the KNHIS national sample cohort who received a KNHIS health check-up in 2008 and 2009, and we followed these individuals until 2017. Patients were defined as having hypopharynx cancer if they had admissions records for hypopharynx cancer in their national health insurance data from 2010 to 2017. Results: The study cohort included 3,922 patients. According to our nationwide data, 3,533(90.1%) were male with a median age of 65.03±11.04 years at the time of diagnosis. Among parametric models for hypopharyngeal cancer prognosis, old age (Hazard ratio [HR]:1.92; 95% confidence interval[CI]:1.76-2.09), female (HR:0.77; 95% CI:0.66-0.89), and low socioeconomic status (HR:1.216; 95% CI:1.114-1.327) were significantly associated with survival. Compared with concurrent chemoradiotherapy, patients who received no treatment (HR, 1.88; 95% CI, 1.31-2.70), neoadjuvant chemotherapy followed by surgery (HR, 1.21; 95% CI, 1.04-1.41), and chemotherapy alone (HR, 1.16; 95% CI, 1.03-1.27) showed poor prognosis in hypopharyngeal cancer. Conclusion: Our data indicated that age, sex, and income were significant predictors of lifetime survival in patients with hypopharyngeal cancer. Treatment modalities were also associated with prognosis. The data have implications for treatment investigations and prevention strategies.

• 한국축산식품학회지
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• 제25권2호
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• pp.226-231
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• 2005

This study was carried out to find the physico-chemical attributes of yogurt base with Lactobacillus case; 00692 during 72 hr fermentation at $37^{\circ}C$. The pH decreased up to 44 hr and plateaued thereafter, and the titratable acidity increased up to 40 hr. The number of lactic acid bacteria sharply increased with $1.0\times10^7cfu/mL$ up to 48 hr of fermentation and slowly increased thereafter. The free amino acids produced during the fermentation reached the maximum value at 40 hr and gradually decreased thereafter. In the result of electrophoresis, the band was the thickest at 44 hr and mostly disappeared at 72 hr fermentation. The present data showed that the range of optimum fermentation time for yogurt base using Lactobacillus casei 00692 was from 40 to 44 hr.

• 한국해양학회지:바다
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• 제6권2호
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• pp.63-70
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• 2001

퇴적물과 해수가 충진된 수조에서 배양실험을 수행하여 해수중 용존산소, pH, 암모니아, 질산염, 철 및 망간 농도의 시간에 따른 변화를 측정하였다. 농도변화 자료를 초기속성작용의 화학 반응식에 적용시켜 퇴적물 내 유기물 분해 초기에 나타나는 유기탄소와 유기질소의 분해정도를 파악하였다. 배양실험은 237 hr 동안 진행되었으며 , 각 화학종의 농도변화 양상에 따라 모두 4개의 시간구간으로 나눌 수 있었다($0{\sim}9\;hr,\;9{\sim}45\;hr,\;45{\sim}141\;hr,\;141{\sim}237\;hr$). 각 시간구간의 농도변화로부터 계산된 유기탄소와 유기질소의 C/N비는 각각 6.63, 1.49, 0.81, 0.02로 시간경과에 따라 감소하였다. C/N비의 감소는 유기물분해 초기에 퇴적물중 유기질소가 유기탄소보다 먼저 선택적으로 분해되어 용출됨을 시사한다. 현장에서 채취한 퇴적물 시료와 배양실험 종료 후 수조에서 수거한 퇴적물중 유기탄소 및 유기질소, 공극수중 암모니아 및 유기탄소 등의 농도변화를 상호 비교한 결과도 유기질소의 선택적 분해를 시사하였다.

• 한국시뮬레이션학회논문지
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• 제22권3호
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• pp.55-69
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• 2013

기업의 전략은 환경 변화에 따라 변화하며 전략의 변화에 따라 최적화된 인적자원관리 제도를 도입 및 실행해야 경영성과 극대화를 달성할 수 있다. 그러나 실질적으로 기업의 자원 및 시간은 한정되어 있기 때문에 활동들 간의 상대적 중요도를 고려하여 우선순위에 따라 단계적으로 추진해야한다. 본 연구는 "CART 앙상블" 분석을 통해 제조업에서의 보편적 관점 및 기업규모 및 전략유형에 따른 상황적 관점에 따라 HR제도 중에서 기업성과를 가장 잘 설명할 수 있는 제도를 찾고 분석결과를 통하여 고성과를 위해 우선적으로 도입해야 할 HR제도의 우선순위를 탐색하였다. 분석결과 보편적 관점에서 기업은 최우선적으로 전략과 인사부서의 통합정도를 높이는데 힘써야 하며, 경영 의사결정 참여도를 높이는 것과 업무속도/방법에 대한 자율재량을 높이는 것이 중요한 것으로 나타났다. 상황적 관점에서도 공통적으로 전략과 인사부서의 통합정도를 높이는 것이 중요하게 나타났으나 그 외의 사항들은 다양한 양상으로 나타났다. 본 연구는 기업의 다양한 상황에 따른 HR제도 우선순위를 파악하는데 주요한 결과를 제시하였다.

• 천문학회보
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• 제46권2호
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• pp.45.2-45.2
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• 2021

Merging of two supermassive black holes would generate gravitational waves that can be detected by the Pulsar Timing Array (PTA) in the nHz band. In order to assess the plausibility of GW detection with PTA and to develop the data analysis scheme, it is important to understand the underlying properties of black holes and black hole binaries. In this work, we present mass and redshift distributions of black hole mergers using the Horizon Run 5 (HR5) data and discuss their implications for GW detection. We find a general conjecture about the black hole merger tree is true with the Horizon Run 5. For example, a) relatively lighter black holes merge at higher redshifts and b) binary mergers do contribute to the formation of more massive black holes toward low redshifts. We also present our plan to use the black hole properties extracted from the HR5 data in order to generate simulated GW signals to be injected into actual PTA data analysis pipelines. Mass and distance obtained from the HR5 would be key ingredients to generate a more realistic PTA source data set.

• BMB Reports
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• 제53권2호
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• pp.112-117
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• 2020

A recent study suggested that methylation of ubiquitin-like with PHD and RING finger domain 1 (UHRF1) is regulated by SET7 and lysine-specific histone demethylase 1A (LSD1) and is essential for homologous recombination (HR). The study demonstrated that SET7-mediated methylation of UHRF1 promotes polyubiquitination of proliferating cell nuclear antigen (PCNA), inducing HR. However, studies on mediators that interact with and recruit UHRF1 to damaged lesions are needed to elucidate the mechanism of UHRF1 methylation-induced HR. Here, we identified that poly [ADP-ribose] polymerase 1 (PARP1) interacts with damage-induced methylated UHRF1 specifically and mediates UHRF1 to induce HR progression. Furthermore, cooperation of UHRF1-PARP1 is essential for cell viability, suggesting the importance of the interaction of UHRF1-PARP1 for damage tolerance in response to damage. Our data revealed that PARP1 mediates the HR mechanism, which is regulated by UHRF1 methylation. The data also indicated the significant role of PARP1 as a mediator of UHRF1 methylation-correlated HR pathway.

• 성인간호학회지
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• 제29권1호
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• pp.98-107
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• 2017

Purpose: The purpose of this study was to investigate the effect of geriatric syndrome on mortality among community-dwelling older adults in Korea. Methods: Data were obtained from the Actual Living Condition of the Elderly and Welfare Need Survey, with a baseline study in 2008 and a 3-year follow-up of mortality data. The mortality risk was measured using the hierarchical Cox proportional hazard model. Results: In Cox regression analysis, male (Hazard Ratio [HR], 2.53; 95% Confidence Interval [CI], 2.12~3.01), old age (HR, 2.14; 95% CI, 1.82~2.53), low education level (HR, 1.31; 95% CI, 1.04~1.65), limitation in instrumental activities of daily living (HR, 1.91; 95% CI, 1.60~2.28), depressive symptoms (HR, 1.21; 95% CI, 1.01~1.43), and frailty (HR, 2.32; 95% CI, 1.78~3.03) significantly affected mortality risk. Conclusion: Based on the results of this study, nursing intervention programs should be provided to decrease preventable death in older adults.

• International Journal of Internet, Broadcasting and Communication
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• 제14권2호
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• pp.212-218
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• 2022

In this paper, the necessity of AI video interview arises when conducting an interview for acquisition of excellent talent in a non-face-to-face situation due to similar situations such as Covid-19. As a matter to be supplemented in general AI interviews, it is difficult to evaluate the reliability and qualitative factors. In addition, the AI interview is conducted not in a two-way Q&A, rather in a one-sided Q&A process. This paper intends to fuse the advantages of existing AI interviews and video interviews. When conducting an interview using AI image analysis technology, it supplements subjective information that evaluates interview management and provides quantitative analysis data and HR expert data. In this paper, image-based multi-modal AI image analysis technology, bioanalysis-based HR analysis technology, and web RTC-based P2P image communication technology are applied. The goal of applying this technology is to propose a method in which biological analysis results (gaze, posture, voice, gesture, landmark) and HR information (opinions or features based on user propensity) can be processed on a single screen to select the right person for the hire.