• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.1722-1726
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• 2008

배수 영향을 받는 가상수로에서 HPG방법과 HPG의 자료를 사용하여 수면경사에 의한 접근방법으로 유량을 보정하였다. 각 case에 대하여, 가정된 상류수위와 유량에 대한 기준유량은 동일하였지만, 하류수위가 상승할수록 배수 영향이 커져 가정유량의 보정량이 크게 나타났다. HPG방법으로 계산된 유량에 대한 수면경사에 의한 접근방법으로 계산된 유량은 고유량에서 4.0%이하의 낮은 상대오차가 나타났다. 따라서 관측자료가 적을 경우, 계산이 쉽지 않은 수면경사에 의한 수위유량곡선방법보다는 HPG방법이 용이하다고 판단된다. 이후 이 방법을 실제 하천에 적용하여 관측유량과 계산유량을 비교, 검토할 계획이다.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.242-242
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• 2016

낙동강 하류구간인 남강합류점에서 낙동강하구둑까지는 하상경사가 약 1/10,000보다 작은 매우 완만한 경사를 이루고 있으므로 홍수기 고수위를 장시간 유지하는 등 홍수소통에 불리한 조건을 가지고 있다. 이처럼 하상경사가 매우 완만한 하천에서는 홍수파의 전파 특성이 하상경사, 수심경사, 그리고 이송가속도와 국부가속도 경사 등 운동량 방정식의 각 항 모두에 영향을 크게 받는 것으로 알려져 있다. 따라서, 낙동강 하류구간의 홍수분석 정확도 개선을 위해서는 대상구간에 유입하는 홍수수문량의 크기 및 변화를 정확히 반영하는 것이 무엇보다 중요하다. 하천 본류로 유입하는 지류의 홍수량을 산정하는 보편적인 방법은 지류 하류의 수위관측소에서 구축된 수위-유량관계곡선을 이용하는 것이다. 그러나 본류 수위의 배수영향을 받는 지류 하류 구간에서는 단일 수위-유량관계의 결정이 불가능하므로 지류 유출량 산정을 위한 새로운 방법이 필요하다. 본 연구에서는 낙동강 하류구간(창녕 함안보~낙동강하구둑) 유역면적의 약 45% 이상을 차지하는 밀양강 유역의 홍수기 유출량 산정을 위하여 HPG(Hydraulic Performance Graph)를 이용하였다. HPG는 배수영향을 받아 시시각각 수리특성이 변화하는 구간에서도 유량 및 상하류 수위 등 수리특성 추정에 합리적인 결과를 제공하는 것으로 알려져 있다. 2012년 태풍 산바 사상을 대상으로 HPG를 이용하여 산정한 밀양강 홍수량과 기존 수위-유량관계로 산정한 홍수량을 각각 경계조건으로 사용한 경우로 구분하여, 낙동강 하류구간 주요 지점인 삼랑진과 구포의 홍수위 예측 정확도를 비교하였다. 비교결과, 기존 방법과 HPG를 이용한 방법 모두 예측시점이 첨두발생 시각에 가까워질수록 평균오차가 감소하는 것으로 분석되었다. 그러나 기존 방법은 예측시점에 따라 평균오차의 변화가 단조롭지 않고 진동이 발생한 반면, HPG를 이용한 방법은 기존 방법보다 오차의 감소가 단조롭고 지속적인 것으로 나타났으며 평균오차 또한 작았다. 본 연구결과, 배수영향을 받는 지류 하류구간에서 HPG를 이용한 유입량 산정은 본류 홍수위 예측 정확도 개선을 위한 경제적인 대안이 될 것으로 판단된다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.6
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• pp.831-838
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• 2018

This paper presents a method to estimate the flow discharge in a backwater affected river junction. First, unsteady HEC-RAS model was simulated and calibrated using 2 recent real flood and then HPG (Hydraulic Performance Graph) was created by plotting the relationship between upstream and downstream stages and discharge in the reach and performing kriging interpolation. During a flood, the discharge through the reach can be estimated based on the stages at its ends and the developed HPG. These discharge data were in good agreement with the automatic discharge measurements such as ADVM. This study could provide an economical and practical method for estimating discharge in a junction with a high hysteresis of stage-discharge relationships.

• Asian-Australasian Journal of Animal Sciences
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• v.4 no.1
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• pp.21-24
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• 1991

A mixed infection of Haemophilus paragallinarum (Hpg), Mycoplasma gallisepticum (MG) and M. synoviae (Ms) was detected in layers of a poultry farm in Iwate prefecture in Japan by pathological, serological and bacteriological investigation. Hpg strains were isolated from three of five birds investigated and all strains were identified to be type C. The Hpg isolates were more susceptible in vitro to a combination of sulfamonomethoxine and ormetoprim (Ektecin) than each of sulfamethoxasol, sulfamonomethoxine, oxytetracycline, tetracycline, streptomycin, erythromycin and thianphinicol. After a total of six days' medication of 1% feed additive Ektecin, symptoms of infectious coryza of hens in the farm almost disappeared and no Hpg was detected even from birds showing nasal discharge.

• Journal of Korea Water Resources Association
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• v.57 no.7
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• pp.481-491
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• 2024

Recent droughts make hydroelectric power generation (HPG) decreasing. Due to climate change in the future, the frequency and intensity of drought are expected to increase, which will increase uncertainty of HPG in multi-purpose dams. Therefore, it is necessary to estimate the amount of HPG according to climate change scenarios and analyze the effect of drought on the amount of HPG. This study analyzed the future HPG of the Soyanggang Dam and Chungju Dam according to the SSP2-4.5 and SSP5-8.5 scenarios. Regression equations for HPG were developed based on the observed data of power generation discharge and HPG in the past provided by My Water, and future HPGs were estimated according to the SSP scenarios. The effect of drought on the amount of HPG was investigated based on the drought severity calculated using the standardized precipitation index (SPI). In this study, the future SPIs were calculated using precipitation data based on four GCM models (CanESM5, ACCESS-ESM1-5, INM-CM4-8, IPSL-CM6A) provided through the environmental big data platform. Overall results show that climate change had significant effects on the amount of HPG. In the case of Soyanggang Dam, the amount of HPG decreased in the SSP2-4.5 and SSP5-8.5 scenarios. Under the SSP2-4.5 scenario the CanESM model showed a 65% reduction in 2031, and under the SSP5-8.5 scenario the ACCESS-ESM1-5 model showed a 54% reduction in 2029. In the case of Chungju Dam, under the SSP2-4.5 and SSP5-8.5 scenarios the average monthly HPG compared to the reference period showed a decreasing trend except for INM-CM4 model.

• Journal of Environmental Health Sciences
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• v.41 no.3
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• pp.147-162
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• 2015

Objectives: The objective of this review was to summarize the primary role of three representative endocrine axes in aquatic vertebrates and discuss the effects on endocrine systems and their interactions in teleost fish after exposure to environmental contaminants. Methods: We summarized individual traits and mechanisms for hormonal and transcriptional interactions between the hypothalamic-pituitary-gonad (HPG), hypothalamic-pituitary-thyroid (HPT), and hypothalamic-pituitary-adrenal (HPA) axes in fish. We also provided a brief discussion on the effects of nonylphenol-induced toxicity on endocrine systems and their interactions in fish as a demonstration of holistic explanation. Results: Currently-available data showed that thyroid dysfunction is associated with reproductive toxicity due to changes in steroidogenic gene expressions and sex hormone levels as well as gonad glands in fish. As an example, we demonstrated that exposure to nonylphenol could induce estrogenicity in male fish by decreasing thyroid hormones, which contributes to increased aromatase expression. Although the mechanisms are complicated and involved in multiple ways, a number of studies have shown that sex steroids influence the HPT axis or the HPA axis in fish, indicating bi-directional crosstalk. Critically missing is information on the primary target or toxicity mechanisms of environmental contaminants among the three endocrine axes, so further studies are needed to explore those possibilities. Conclusions: This review highlights the interactions between the HPG, HPT, and HPA axes in fish in order to better understand how these endocrine systems could interact with each other in situations of exposure to endocrine disrupting chemicals.

• Development and Reproduction
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• v.13 no.4
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• pp.207-215
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• 2009

Numerous factors can affect the activities of hypothalamus-pituitary-gonad (HPG) hormonal axis, resulting in alteration of reproductive capacity or status such as onset of puberty and menopause. Soon after the finding of leptin, a multifunctional hormone secreted from adipocytes, a close relationship between reproduction and body energy balance have been manifested. Ghrelin, another multifunctional hormone from gastrointestinal tract, is an endogenous ligand of growth hormone secretagogue receptor (GHSR), and is thought to be a counterpart of leptin in the regulation of energy homeostasis. As expected, ghrelin can also modulate the reproductive capacity through the modulation of activities of HPG axis. This paper summarizes the current knowledge on the discovery, gene structures, tissue distribution and roles of ghrelin and GHSRs in mammalian reproduction in particular modulation of reproductive hormone secretion in HPG axis. Like POMC gene expression in pituitary gland, preproghrelin gene can generate a complex repertoire of transcripts which further undergo alternative splicing and posttranslational modifications. Concerning the roles of preproghrelin gene products in the control of body physiology except energy homeostasis, limited knowledge is available so far. Several lines of evidence, however, show the interplay of ghrelin between metabolism and reproduction. In rat and human, the distribution of ghrelin receptor GHSRs (GHSR1a and GHSR1b) has been confirmed not only in the hypothalamus and pituitary which were originally postulated as target of ghrelin but also in the testis and ovary. Expression of the preproghrelin gene in the brain and gonads was also verified, suggesting the local role (s) of ghrelin in HPG axis. Ghrelin might play a negative modulator in the secretions of hypothalamic GnRH, pituitary gonadotropins and gonadal steroids though the action on pituitary is still questionable. Recent studies suggest the involvement of ghrelin in regulation of puberty onset and possibly of menopause entry. It is now evident that ghrelin is a crucial hormomal component in 'brain-gut' axis, and is a strong candidate links between metabolism and reproduction. Opposite to that for leptin, ghrelin signaling is likely representing the 'hunger' state of body energy balance and is necessary to avoid the energy investment into reproduction which has not a top priority in maintaining homeostasis. Further researches are needed to gain a deep insight into the more precise action mechanism and role of ghrelin in reproduction, and to guarantee the successful biomedical applications.

• Clinical and Experimental Reproductive Medicine
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• v.40 no.4
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• pp.155-162
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• 2013

Objective: Stress is known to be an inhibitor of the reproductive hypothalamic-pituitary-gonadal (HPG) axis. However, the neural and molecular connections between stress and reproduction are not yet understood. It is well established that in both humans and rodents, kisspeptin (encoded by the kiss1 gene) is a strong stimulator of the HPG axis. In the present study we hypothesized that endocannabinoids, an important neuromodulatory system in the brain, can act on the HPG axis at the level of kiss1 expression to inhibit reproductive function under stress. Methods: Adult male Wistar rats were unilaterally implanted with an intracerebroventricular cannula. Afterwards, the animals were exposed to immobilization stress, with or without the presence of the cannabinoid CB1 receptor antagonist AM251 (1 ${\mu}g/rat$). Blood samples were collected through a retro-orbital plexus puncture before and after stress. Five hours after the stress, brain tissue was collected for reverse transcriptase-quantitative polymerase chain reaction measurements of kiss1 mRNA. Results: Immobilization stress (1 hour) resulted in a decrease in the serum luteinizing hormone concentration. Additionally, kiss1 gene expression was decreased in key hypothalamic nuclei that regulate gonadotrophin secretion, the medial preoptic area (mPOA), and to some extent the arcuate nucleus (ARC). A single central administration of AM251 was effective in blocking these inhibitory responses. Conclusion: These findings suggest that endocannabinoids mediate, at least in part, immobilization stress-induced inhibition of the reproductive system. Our data suggest that the connection between immobilization stress and the HPG axis is kiss1 expression in the mPOA rather than the ARC.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.393-393
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• 2015

대부분의 중규모 유역 내에는 하도가 형성되므로, 유역의 출구는 하도(지류)와 대규모 유역의 하도(본류)가 합류하게 되며, 합류부에서 멀리 떨어지지 않은 곳에 지류 유역의 유출량 산정을 위한 수위관측소가 위치하게 된다. 수위관측소에서는 일반적으로 연속적인 수위관측과 수위-유량관계곡선(rating curve)으로 유량을 산정하게 되는데, 배수영향을 크게 받는 합류부 구간에서는 단일 수위-유량관계가 나타나지 않으므로 유량산정이 어렵게 되는 문제가 발생한다. 이는 배수영향이 발생할 경우, 유량 함수의 주요 변수에는 수위 뿐만 아니라 수면경사 등의 매개변수가 추가되기 때문이다. 현장에서는 하천 흐름방향으로 두 개의 수위관측소를 설치하여 관측소 간의 수면경사를 측정하고, 이를 유량 산정에 활용할 수 있다. 그러나 지류 합류부의 배수 영향 구간에서 수면경사를 알기 위하여 두 개의 수위관측소를 설치하는 것은 경제적이지 않으며, 현재 설치되어 있는 장비와 시설을 활용하여 유량을 산정할 수 있는 방법의 개발이 필요하다. 본 논문의 목적은 합류부 배수영향을 받는 지류 구간에 설치된 수위관측소에서 유량을 산정하기 위한 방법을 개발하는 것이다. 이를 위하여 발생가능한 모든 하천 흐름조건에 대한 배수영향 수면곡선을 요약한 HPG(Hydraulic Performance Graph)를 본류와 지류가 합류하는 시스템에 적용하였다. HPG의 개발을 위하여 본류와 지류로 구성된 수지상 하천망을 HEC-RAS 모형으로 구축하고 부정류 모의로 구축된 모형을 보정 검증하였고, 본류와 지류에 위치한 기존 두 수위관측소 수위와 유량과의 관계 표를 작성하여 크리깅 보간을 수행하였다. 크리깅으로 보간된 HPG와 두 수위관측소에서 계측된 수위를 이용하여 대상 홍수사상 기간 금호강의 유출량을 산정하였고, 유량 산정 결과는 금호강 성서 자동유량측정 자료와 거의 일치하는 것을 확인하였다.

• Clinical Nutrition Research
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• v.13 no.1
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• pp.8-21
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• 2024

In this study, the effects of a 12-month multidisciplinary education program on the health status, dietary quality, and eating habits of children and adolescents attending community childcare centers were investigated. A total of 88 participants aged 7 to 17 years from 7 community childcare centers in Gyeonggi-do were enrolled. The intervention consisted of 12 multidisciplinary education sessions covering topics such as nutrition, exercise, and psychological education. All participants received the same education, and the effectiveness of the program was evaluated by categorizing them into a high participation group (HPG) and a low participation group (LPG) based on their participation rates. After intervention, in physical activities, moderate-intensity exercise was significantly reduced in the LPG, and there was no significant difference in psychological parameters. However, notable differences were observed in nutritional data. After intervention, intakes of calorie, carbohydrate, protein, and fat were significantly increased in both groups, and in particular, the change was found to be greater in HPG. Additionally, dietary fiber intake compared to the 2015 Korean Dietary Reference Intakes was increased in both groups. Daily food intake also increased dietary fiber intake in HPG, and meat and fruit intake was increased in LPG. In the nutrition quotient, there was a significant difference in HPG's pre- and post-scores in the diversity category, and in nutrient adequacy ratio (NAR), the NAR of phosphorus was increased in both groups. The findings of this study suggest that multidisciplinary education implemented at community childcare centers primarily enhanced nutrition-related factors rather than physical activity or psychological aspects.