• Title/Summary/Keyword: HMP

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Effect of Hericium erinaceus Mycelia Supplementation on the Oxidative Stress and Inflammation Processes Stimulated by LPS and Their Mechanisms in BALB/C Mice (BALB/C Mice에서 노루궁뎅이버섯 균사체 보충이 LPS로 인한 산화적 스트레스와 염증 반응에 미치는 효과 및 기전)

  • Jang, Ji-Hyun;Noh, Kyung-Hee;Choi, Ji-Na;Jin, Kyong-Suk;Shin, Jin-Hyuk;On, Joon-Ho;Cho, Chung-Won;Jeong, Woo-Sik;Kim, Myo-Jeong;Song, Young-Sun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.2
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    • pp.227-236
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    • 2010
  • This study was carried out to investigate the anti-oxidative and anti-inflammatory actions of Hericium erinaceus mycelia in BALB/C mice injected with lopopolysaccharide (LPS), called endotoxin. Mice (6 weeks of age) weighing approximately $24.73\pm0.11$ g were divided into 5 groups and were fed on the experimental diets containing Hericium erinaceus mycelia powder (HMP) for 1 week. Experimental groups were NC (normal control), HMP-C (HMP control), LC (LPS control), HMP 3%, and HMP 10%. Endotoxin shock was induced by intraperitoneal injection of LPS (100 mg/kg BW). NC and HMP-C groups were injected with saline solution (100 mg/kg BW). Food efficiency ratio were significantly (p<0.05) decreased in the HMP supplementation groups. Total fat and $\beta$-glucan excretion were higher in HMP supplementation groups than NC and LC groups, while plasma TG level was not different among groups. Plasma ALT levels were significantly (p<0.05) lower in the HMP supplementation groups than in LC group at 8 hr after LPS injection, while tumor necrosis factor-$\alpha$ and interleukine-6 levels of plasma were not different among groups. Hepatic superoxide dismutase, glutathione-reductase (GSH-red), and glutathione-peroxidase activities were higher in the HMP supplementation groups than in LC group at 4 hr after intraperitoneal injection of LPS. Hepatic GSH levels and protein expression of GSH-red was significantly (p<0.05) higher in the HMP supplemented groups than in LC group at 1 hr, 4 hr and 8 hr after LPS injection. From the above results, it is concluded that Hericium erinaceus mycelia may ameliorate hepatic oxidative stress by LPS through the elevation of hepatic glutathione level and antioxidant enzyme activities, which support the hepatoprotective effect of Hericium erinaceus mycelia.

Changes in the Pectic Substance during Maturity of Apple (사과의 성숙에 따른 Pectin질의 변화)

  • Kim, Yeung-Ji;Kim, Chang-Sik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.1
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    • pp.63-68
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    • 1988
  • The changes of methoxy content. compositional sugars. degree of esterification (DE) and pectic substances such as LMP (low methoxy pectin), HMP (high methoxy pectin) IAP (ionically associated pectin) and CBP (covalently bounded pectin) of Fuji apple were investigated during maturity. The contents of LMP+HMP and IAP+CBP in alcohol insoluble solid(AIS) were 70% and 20%. respectively. These pectic substances were increased slightly during maturity. The reductions of hexose and uronic acid were Iron 20-50% and from 2-4%, respectively, but the inclosed of pentose was from 1-9% in LMP, HMP, IAP and CBP during maturity of Fuji apple. The galactose was decreased significantly among hexose. Whereas the relative ratio of uronic acid in HMP and CBP was increased.

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Antimicrobial effect of Enterococcus faecalis BMSE-HMP005 isolated from human breast milk against multidrug-resistant bacteria (모유 유래 유산균 Enterococcus faecalis BMSE-HMP005의 다제내성 균에 대한 항균효과)

  • Lee, Jeong-Eun;Kim, Soo-bin;Yu, Du-na;Jo, So-Yeon;Kim, Ae-Jung;Kook, Moochang
    • Korean Journal of Food Science and Technology
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    • v.54 no.2
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    • pp.209-217
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    • 2022
  • In this study, Enterococcus faecalis BMSE-HMP005 isolated from human breast milk demonstrated antimicrobial effects against multidrug-resistant (MDR) bacterial strains. The bacteriocin produced by E. faecalis BMSE-HMP005 was fractionated using reverse-phase high-performance liquid chromatography. This fraction showed antimicrobial effects against both gram-positive and gram-negative MDR bacteria. No hemolytic reactions were observed. E. faecalis BMSEHMP005 was resistant to vancomycin; however, kanamycin, ampicillin, and erythromycin showed minimum inhibitory concentrations that were lower than the acceptable range provided by the European Food Safety Authority. For artificial gastric juice and bile acid, the survival rates were 98.67% and 95.70%, respectively. These results show the potential utility of E. faecalis BMSE-HMP005 as a probiotic with remarkable antimicrobial effects against MDR bacteria.

An Adaptive Joint Precoding for Multi-user MIMO Systems (다중 사용자 MIMO 시스템을 위한 적응적 결합 프리코딩)

  • Park, Ju Yong;Hanif, Mohammad Abu;Song, Sang Seob;Lee, Moon Ho
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.12
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    • pp.3-11
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    • 2014
  • Multiple antennas can provide huge capacity gains when the transmitter knows the channel state information (CSI). Precoding is a technique that exploits CSI at the transmitter side. In this paper, an adaptive precoding scheme is proposed, called a hybrid multiple-input multiple-output (MIMO) precoding (HMP). HMP is a combination of linear and nonlinear precoding. The number of transmit antennas less than or equal to four is as same as the conventional antenna selection scheme. Therefore, the HMP scheme uses more than four transmit antennas. The good channel means that the channels must be selected to maximize the channel capacity among the given channels, and the rest channels are called bad channel. In HMP scheme, we use the nonlinear precoding in the good channels and the linear precoding in the bad channels. The well-known Tomlinson-Harashima precoding (THP) is considered as nonlinear precoding. The system throughput and MSE (minimum square error) are shown for the performance of HMP scheme compared to the conventional schemes which are BD (block diagonalization), antenna selection and THP.

A Cost-Aware Multi-path DSDV Routing Protocol in Wireless Mesh Networks (무선 메쉬 네트워크에서 비용 인지 다중 경로 DSDV 라우팅 프로토콜)

  • Lee, Seong-Woong;Chung, Yun-Won
    • The KIPS Transactions:PartC
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    • v.15C no.4
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    • pp.289-296
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    • 2008
  • In wireless mesh network, studies on routing protocols have been actively carried out recently, and hop count is used as a major routing metric in destination-sequenced distance-vector (DSDV) routing protocol, which is a representative proactive routing protocol. Although hop-by-hop multi-path (HMP) DSDV and enhanced HMP (EHMP) DSDV routing protocols perform routing by considering both hop count and residual bandwidth within one hop distance nodes, it has a shortcoming that routing is carried out via non-optimal path from the aspect of end-to-end routing. In order to overcome the shortcoming, a cost-aware multi-path (CAMP) DSDV routing protocol is proposed in this paper, which considers hop count and end-to-end minimum residual bandwidth. Simulation results based on NS-2 show that the proposed routing protocol performs better than DSDV, HMP DSDV, and EHMP DSDV protocols from the aspect of throughput and packet delivery ratio, by appropriately using hop count and end-to-end minimum residual bandwidth information and has the same number of management messages with HMP DSDV and EHMP DSDV protocols.

Anti-Hemolytic and Antimicrobial Effects against Multidrug-Resistant Bacteria of Enterococcus faecalis Isolated from Human Breast Milk (모유에서 분리한 Enterococcus faecalis의 다제내성 균에 대한 항용혈 및 항균 효과)

  • Yi, Eun-Ji;Lee, Jeong-eun;Jo, So-Yeon;Kim, Soo-bin;Yu, Du-na;Kook, Moochang;Kim, Ae Jung
    • Microbiology and Biotechnology Letters
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    • v.49 no.4
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    • pp.519-527
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    • 2021
  • In this study, the hemolysis of Enterococcus faecalis BMSE-HMP strains, isolated from human breast milk, was investigated, and the anti-hemolytic and antimicrobial effects on multidrug-resistant (MDR) bacteria were investigated. The enzyme activity of E. faecalis BMSE-HMP 4 strains was measured, and it was found that the activities of esterase and esterase lipase were the highest. In addition, no hemolytic reaction was observed in any of the isolates. Subsequently, the anti-hemolytic activity against MDR strains causing hemolysis was evaluated. E. faecalis BMSE-HMP002 had the highest anti-hemolytic activity against Staphylococcus aureus CCARM 3855 at 75.71 ± 10.00%. The anti-hemolytic activity against Escherichia coli DC 2 CCARM 0238 and Pseudomonas aeruginosa CCARM 0223 showed that the activity of BMSE-HMP001 was highest at 76.92 ± 2.99% and 87.93 ± 1.93%, respectively. Examination of the antimicrobial effects against the MDR bacteria Staphylococcus spp., Escherichia spp., Pseudomonas spp., Salmonella spp., Klebsiella spp., Enterobacter spp., and E. faecalis BMSE-HMP strains showed antimicrobial effects against both gram-positive and gram-negative strains. Breastfeeding delivers enterococci into the intestinal tract of newborns by lactation, and its usefulness is attracting attention as it has been reported that enterococci have a potential effect on neonatal immune development. In this study, the hemolytic and antimicrobial effects of E. faecalis BMSE-HMP strains on MDR bacteria were investigated, to confirm their potential as useful lactic acid bacteria. Additional studies on the antibiotic resistance and toxicity of the E. faecalis BMSE-HMP strains, isolated in this study, are necessary to prove it safe for use.

Replacement of sucrose with other sweeteners and high methoxyl pectin in low caloric pectin gels (대체 감미료와 high methoxyl pectin을 이용한 저열량 pectin gel의 제조)

  • 오혜숙;이명희;문수재
    • Korean journal of food and cookery science
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    • v.9 no.4
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    • pp.284-288
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    • 1993
  • Replacement of sucrose with sugar alcohols in high methoxyl pectin(HMP) jellies were studied. HMP jellies were sweetened with 100% sucrose, 75% sucrose and 25% maltitol, 50% sucrose and 50% maltitol, and 50% sucrose, 25% maltitol, 12.5% sorbitol and 12.5% mannitol. The effect of sugar alcohols in HMP jellies were investigted. There was only slight differences in sweetness intersity in HMP jellies. Color(p<0.05), texture(p<0.01) and preference(p<0.01) of 100fl sucrose jelly were significantly higher than other Jellies sweetened with sugar and sugar alcohols mixtures. Hunter's L(lightness), a(redness), b(yellowness) values of 100%, sucrose jellies and jellies substituted with maltitol up to 25% were not signignificantly different. But as the ratio and the number of sugar alcohols used for substition were increased, L, a and b values had been lowered signigicantly(p<0.01). Instru-mental characteristics of jelly texture were examined. Hardness of 100% sucrose jelly sweetened with sucrose and 3 kind of sugar alcohols were higher than others(p<0.05). As substitution ratio was higher, springiness and chewiness of HMP jellies were lowered(p<0.01). Springiness of HMP jellies indicated positive correlation with general acceptance of sensory scores at 5% significant level. Brittleness, gum-miness and cohesiveness in all types of jellies were not significantly different.

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Effects of Prepartum Energy Intake and Calving Season on Blood Composition of Periparturient Cows

  • Toharmat, T.;Nonaka, I.;Shimizu, M.;Batajoo, K.K.;Kume, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.6
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    • pp.739-745
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    • 1998
  • Sixteen periparturient Holstein cows calving during summer and autumn were fed to meet maintenance plus last 2 month of gestation level of TDN (MP) and 1.2 time of MP level (HMP). Dry matter intake of cows fed at HMP level during summer and autumn decreased by 1 and 2% of the offered feed in 1 week prepartum, respectively, and cows fed at MP level consumed all of the offered feed. Rectal temperatures at 08 : 30 h of cows fed at HMP level were higher than those of cows fed at MP level. Blood hematocrit and hemoglobin of cows increased during summer and were higher for cows fed at HMP level. Plasma total protein and glucose of cows during summer were higher than those during autumn, and the increased feed intake elevated plasma total protein and glucose. Plasma urea-N of cows fed at MP level was higher than that of cows fed at HMP level during autumn. The increased feed intake decreased plasma nonesterified fatty acid of cows during summer and autumn. These results suggest that blood components of periparturient cows are altered by calving season and feeding level.

Outcomes of Home Monitoring after Palliative Cardiac Surgery in Infants with Congenital Heart Disease (선천성 심질환으로 고식적 수술을 시행 받은 영아의 홈모니터링의 성과)

  • Kim, Sang Wha;Uhm, Ju-Yeon;Im, Yu Mi;Yun, Tae-Jin;Park, Jeong-Jun;Park, Chun Soo
    • Journal of Korean Academy of Nursing
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    • v.44 no.2
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    • pp.228-236
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    • 2014
  • Purpose: Common conditions, such as dehydration or respiratory infection can aggravate hypoxia and are associated with interstage mortality in infants who have undergone palliative surgery for congenital heart diseases. This study was done to evaluate the efficacy of a home monitoring program (HMP) in decreasing infant mortality. Methods: Since its inception in May 2010, all infants who have undergone palliative surgery have been enrolled in HMP. This study was a prospective observational study and infant outcomes during HMP were compared with those of previous comparison groups. Parents were trained to measure oxygen saturation, body weight and feeding volume and to contact the hospital through the hotline for emergency situations. Telephone counseling was conducted by clinical nurse specialists every week post discharge. Results: Forty-one infants were enrolled in HMP. Nine hundred telephone counseling sessions were conducted. Seventy-three infants required telephone triage with the most common conditions being gastrointestinal (50.7%) and respiratory symptoms (32.9%). With HMP intervention, interstage mortality decreased from 18.6% (8/43) to 9.8% (4/41) (${\chi}^2$=1.15, p=.283). Conclusion: Results indicate that active measures and treatments using the HMP decrease mortality rates, however further investigation is required to identify various factors that contribute to hemodynamic complications during the interstage period.