• Tuberculosis and Respiratory Diseases
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• v.61 no.6
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• pp.554-561
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• 2006

Background: In AIDS patients, the respiratory tract is one of the most frequently involved site of by an opportunistic infection, and an even common, casual pulmonary infection manifests in a peculiar ways in AIDS patients. In Korea, because of the low prevalence of AIDS, there is insufficient data compared with other Southeast Asian counties. However, considering the sexual behavior of the younger generation, it is expected that it will not be long before AIDS becomes a major public health issue in Korea. This study examined the clinical manifestation of HIV positive people and AIDS patients. The pulmonary manifestion of HIV-positive was evaluated. This study focused on the differences in the clinical manifestation between AIDS patients with pulmonary disease and simple HIV positive people. The characteristics of common pulmonary infections in AIDS patients were also analyzed. Method: The medical records of 28 HIV positive patients who visited the hospital of ChungAng University Hospital from January, 2001 to February, 2006 were analyzed retrospectively. Result: Twenty-seven patients out of 28 HIV positive patients were male and the average age was 40.6(23-65). Patients in their thirties were most commonly affected. Elven patients had pulmonary diseases. Pulmonary tuberculosis (4 cases) and pneumocystis pneumonia (4 cases) were the most common respiratory infection. One patient showed a peculiar type of systemic cryptococcus. which was accompanied by lung and pleural dissemination. The CD4+lymphocyte count of patients with a pulmonary infection was significantly lower in patients with a pulmonary manifestation than those with only a HIV infection ($79.5/mm^3$ vs $400/mm^3$, respectively)(p<.05). Patients with pulmonary disease were in a more severe immunosuppressive state. There were 4 patients with pulmonary tuberculosis, 4 with pneumocystis pneumonia, 4 with secondary syphilis, 2 with primary syphilis, and 2 with HZV infection. The average CD4 lymphocyte counts was $56/mm^3$ in those with pulmonary tuberculosis, $42/mm^3$ in those with pneumocystis pneumonia, and $455/mm^3$ in those with secondary syphilis. Conclusion: This study examined the clinical manifestation of HIV positive patients, particularly AIDS patients with pulmonary disease, A more severe immunosuppressive status was observed in HIV-related pulmonary compared with those with HIV-related extrapulmonary disease, and the frequency of pulmonary tuberculosis in pulmonary disease was higher than expected. Respiratory infection in AIDS manifest in uncommon ways e.g. disseminated cryptococcosis involving the lung and pleura. Evidently, AIDS patients with a respiratory infection have a more severe form of immunosuppression than those with a simple HIV infection. As expected, patients with a pulmonary infection were in a more severe immunosuppressed state than those with a simple HIV infection. Opportunistic infections can show peculiar clinical presentations in AIDS patients.

• Clinical and Experimental Pediatrics
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• v.57 no.3
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• pp.117-124
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• 2014

Purpose: Administration of antiretroviral drugs to mothers and infants significantly decreases mother-to-child human immunodeficiency virus (HIV) transmission; cesarean sections and discouraging breastfeeding further decreases this risk. The present study confirmed the HIV status of babies born to mothers infected with HIV and describes the characteristics of babies and mothers who received preventive treatment. Methods: This study retrospectively analyzed medical records of nine infants and their mothers positive for HIV who gave birth at Korea University Ansan Hospital, between June 1, 2003, and May 31, 2013. Maternal parameters, including HIV diagnosis date, CD4+ count, and HIV ribonucleic acid (RNA) copy number, were analyzed. Infant growth and development, HIV RNA copy number, and HIV antigen/antibody test results were analyzed. Results: Eight HIV-positive mothers delivered nine babies; all the infants received antiretroviral therapy. Three (37.5%) and five mothers (62.5%) were administered single- and multidrug therapy, respectively. Intravenous zidovudine was administered to four infants (50%) at birth. Breastfeeding was discouraged for all the infants. All the infants were negative for HIV, although two were lost to follow-up. Third trimester maternal viral copy numbers were less than 1,000 copies/mL with a median CD4+ count of $325{\mu}L$ ($92-729{\mu}L$). Among the nine infants, two were preterm (22.2%) and three had low birth weights (33.3%). Conclusion: This study concludes that prophylactic antiretroviral therapy, scheduled cesarean section, and prohibition of breastfeeding considerably decrease mother-to-child HIV transmission. Because the number of infants infected via mother-to-child transmission may be increasing, studies in additional regions using more variables are necessary.

• Korean Journal of Psychosomatic Medicine
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• v.11 no.1
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• pp.15-24
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• 2003

Objectives: The object of this study was to compare perceived stress and quality of life among patients with HIV infection, patients with pulmonary tuberculosis and normal controls. Methods: Stress response inventory(SRI) and Symptom checklist 90-Revised(SCL-90-R) were used to measure perceived stress responses and psychopathology. Smithklein Beecham quality of life scale was used to measure quality of life. Results: Patients with HIV infection scored significantly higher on scores of tension, anger, depression, fatigue and frustration subscale of the SRI than those with pulmonary tuberculosis and normal controls. Scores of the SCL-90-R, somatization, depression, anxiety, hostility, phobic anxiety, paranoid ideation and psychoticism subscale were also significantly higher in patients with HIV infection than those with pulmonary tuberculosis and normal controls. Patients with HIV infection scored significantly lower in quality of life than those with pulmonary tuberculosis. In patients with HIV infection, age had a significantly negative correlation with scores of somatization, obsessive-compulsive, interpersonal sensitivity, phobic anxiety, paranoid ideation and psychoticism subscale of the SCL-90-R. but the level of education had a significantly positive correlation with somatization, obsessive-compulsive, interpersonal sensitivity, phobic anxiety, paranoid ideation and psychoticism subscale of the SCL-90-R. Conclusion: The results suggest that patients with HIV positive were likely to have higher levels of perceived stress response and psychopathology, and lower quality of life than those with pulmonary tuberculosis and normal controls.

• Women's Health Nursing
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• v.11 no.2
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• pp.110-119
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• 2005

Purpose: The purpose of this study was to illuminate the life experiences of 10 Korean men with HIV. Method: This is qualitative research using a grounded theory methodology. Result: A core category - enduring under the yoke of HIV and 5 subcategories emerged: Accepting the fact of HIV infection unwillingly with shock, Conflict between the secret concealment and disclosure, Resisting social prejudice and discrimination, Change of the daily life and management of health, Remembering their past lives without HIV and reconstructing their own lives with HIV. Conclusion: The findings contributed to understanding the HIV/AIDS illness experiences among men with hetero & homo sexuality, and revealing the prejudice against HIV in Korean society. The results have very important implications for health care professionals working with HIV-positive men.

• Korean Journal of Psychosomatic Medicine
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• v.10 no.2
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• pp.120-129
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• 2002

Objectives : The object of this study was to compare perceived stress and quality of life among patients with HIV infection, patients with pulmonary tuberculosis and normal controls Methods: Stress Response Inventory(SRI) and Symptom checklist 90-Revised(SCL-90-R) were used to measure perceived stress responses and psychopathology. Smithklein Beecham quality of life scale was used to measure quality of life. Results : Patients with HIV infection scored significantly higher on scores of tension, anger, depression, fatigue and frustration subscale of the SRI than those with pulmonary tuberculosis and normal controls. Scores of the SCL-90-R, somatization, depression, anxiety, hostility, phobic anxiety, paranoid ideation and psychoticism subscale were also significantly higher in patients with HIV infection than those with pulmonary tuberculosis and normal controls. Patients with HIV infection scored significantly lower in quality of life than those with pulmonary tuberculosis. In patients with HIV infection, age had a significantly negative correlation with scores of somatization, obsessive-compulsive, interpersonal sensitivity, phobic anxiety, paranoid ideation and psychoticism sub scale of the SCL-90-R. but the level of education had a significantly positive correlation with somatization, obsessive-compulsive, interpersonal sensitivity, phobic anxiety, paranoid ideation and psychoticism sub scale of the SCL-90-R. Conclusion : The results suggest that patients with HIV positive were likely to have higher levels of perceived stress response and psychopathology, and lower quality of life than those with pulmonary tuberculosis and normal controls.

• The Journal of Advanced Prosthodontics
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• v.6 no.1
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• pp.30-34
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• 2014

PURPOSE. This study evaluated the adhesion to acrylic resin specimens and biofilm formation capability of Candida albicans strains isolated from HIV positive subjects' oral rinse solutions. MATERIALS AND METHODS. The material tested was a heat-cured acrylic resin (Acron Duo). Using the adhesion and crystal violet assays, 14 oral Candida albicans isolated from HIV-positive subjects and 2 references Candida strains (C. albicans ATCC 90028 and C. albicans ATCC 90128) were compared for their biofilm production and adhesion properties to acrylic surfaces in vitro. RESULTS. There were no significant differences in adhesion (P=.52) and biofilm formation assays (P=.42) by statistical analysis with Mann-Whitney test. CONCLUSION. Denture stomatitis and increased prevalence of candidal carriage in HIV infected patients is unlikely to be related to the biofilm formation and adhesion abilities of C. albicans to acrylic resin materials.

• Journal of Hospice and Palliative Care
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• v.12 no.1
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• pp.14-19
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• 2009

Purpose: The purpose of this study was to provide basic data to assess spiritual health of HIV/AIDS patients and devise spiritual nursing mediation plans in practical nursing work by examining the levels of spiritual wellbeing (SWB) and spiritual needs of HIV/AIDS patients'. Methods: A correlation survey study was conducted on HIV/AIDS patients age ranging from 20 to 70 years to investigate the relationship between their SWB and spiritual needs. Results: 1. Average scores of HIV/AIDS patients' related to SWB were found to be higher than the intermediate level: 54.59 in SWB; more specifically, 27.78 in existential well-being and 26.80 in religious well-being. 2. Average score of for HIV/AIDS patients' spiritual needs was 108.67: More specifically, 37.80 in the needs of love and interest, 42.35 in the needs of seeking meanings and purposes, and 28.51 in the needs of wanting to be forgiven. 3. Concerning the correlation between SWB and spiritual needs, the total SWB and total spiritual needs of HIV/AIDS patients' showed a weak positive correlation (r=0.344, P=0.013). Conclusion: The result of the study showed that SWB and spiritual needs of HIV/AIDS patients' are higher than the average scores, and these two parameters have a weak positive correlation, indicating that HIV/AIDS patients have strong spiritual needs of seeking meanings and purposes. Therefore, more studies on the spiritual nursing mediation plans are needed in order to raise their spiritual well-being levels and meet their spiritual needs through precise assessment.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.27 no.2
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• pp.95-103
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• 2024

Purpose: Diarrhea is one of the leading causes of mortality in children living in developing countries. The etiology of acute diarrhea in each healthcare center varies depending on place, time, and population. This study aimed to identify pathogen patterns in human immunodeficiency virus (HIV)-infected and non-HIV children suffering from acute diarrhea, using multiplex real time reverse transcriptase polymerase chain reaction (RT-PCR), in an Indonesian tertiary hospital. Methods: This cross-sectional study was conducted at Dr. Cipto Mangunkusumo National Hospital from March 2019 to April 2020. Results: The study showed that multiplex RT-PCR results were positive in 58.9% of the specimens, with more positive results in HIV-infected children than in non-HIV-infected children (70% vs. 54.7%). Altogether 72 enteropathogens were detected from all specimens. Enteropathogens in non-HIV children with acute diarrhea consisted of bacteria (70.6%) and viruses (29.4%) with a predominance of enteroaggregative Escherichia coli (25.4%), followed by Campylobacter spp. (11.8%), enteropathogenic E. coli (9.8%), Norovirus GII (7.8%), and Clostridium difficile (7.8%). Enteropathogens in HIV-infected children consisted of viruses (57.1%), bacteria (28.6%), and parasites (14.3%) comprising Norovirus GII (24%), Cryptosporidium spp. (14.3%), Campylobacter spp. (14.3%), Norovirus GI (14.3%), and Astrovirus (14.3%). Cryptosporidium spp. was the only parasite found in this study and was found only in HIV-infected children. In non-HIV children with acute diarrhea, most pathogens were invasive bacteria, while in HIV-infected children, more viral and parasite infections occurred, primarily caused by opportunistic pathogens. Conclusion: The pattern of enteropathogens can help clinicians determine further examinations and appropriate empirical antimicrobial therapy for the patient.

• RED RIBBON
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• s.68
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• pp.10-11
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• 2006

HIV에 감염되었다는 것은 질병을 얻었다는 것 외에도 정신적 충격이 거의 동반된다. 그 이유는 에이즈 발견초기 병의 감염경로나 예방법이 알려지지 않은 상태에서 공포와 두려움으로 에이즈를 알렸기 때문이다. 25년이 지난 지금에도 HIV에 감염되지 않은 사람은 감염된 사람을 부정하고 낙인찍기를 서슴치 않고, 이런 이유로 감염된 사람들은 자신의 감염사실에 좌절하고 분노하기에 이른다. 그렇다면 HIV에 감염된 초기 감염인들은 자신의 감염사실을 어떻게 받아들이는 게 좋은지 포즈닷컴의 유용한 정보를 번역하여 게재하도록 한다. positive life 는 HIV 감염인들에게 유용한 정보를 매호 제공할 예정이다.

• Communications for Statistical Applications and Methods
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• v.8 no.3
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• pp.815-822
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• 2001

The aim of this study is to estimate the seroconversion date of the human immunodeficiency virus(HIV) infection for the HIV infected patients in Korea. Data are collected from two cohorts. The first cohort is a group of "seroprevalent" patients who were seropositive and AIDS-free at entry. The other is a group of "seroincident" patients who were initially seronegative but later converted to HIV antibody-positive. The seroconversion dates of the seroincident cohort are available while those of the seroprevalent cohort are not. Estimation of seroconversion date is important because it can be used to calculate the incubation period of AIDS which is defined as the elapsed time between the HIV infection and the development of AIDS. In this paper, a Weibull regression model Is fitted for the seroincident cohort using information about the elapsed time since seroconversion and the CD4$^{+}$ cell count.The seroconversion dates for the seroprevalent cohort are imputed on the basis of the marker of maturity of HIV infection percent of CD4$^{+}$cell count.unt.