• Journal of the Ergonomics Society of Korea
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• v.23 no.3
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• pp.73-88
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• 2004

This study was contrived Hierarchical Information Search (HIS) model. HIS model is based on a “cognitive process” in which model, comprising basic human information processing mechanize and information interaction. Its process include 3 semantic cognitive processes: Schema-Association LTM, Form Domain, and Alternative Selection. Design methodology consists to elicitate memory, thinking and cognitive response variables. In case study, menu structure of mobile phone was applied. In result, a correlation between predictive error rate and real error rate was .892. and a correlation between selective and real reaction time was .697. This present to suggest a model of how the methodology could be applied to real system design effectively when this was used. HIS model could become one of the most important factors for success of product design. In the perspective, the systemic methodology would contribute to design a quantitative and predictive system.

• Genomics & Informatics
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• v.17 no.1
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• pp.10.1-10.3
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• 2019

To identify miRNA-mRNA interaction pairs associated with binary phenotypes, we propose a hierarchical structural component model for miRNA-mRNA integration (HisCoM-mimi). Information on known mRNA targets provided by TargetScan is used to perform HisCoM-mimi. However, multiple databases can be used to find miRNA-mRNA signatures with known biological information through different algorithms. To take these additional databases into account, we present our advanced application software for HisCoM-mimi for binary phenotypes. The proposed HisCoM-mimi supports both TargetScan and miRTarBase, which provides manually-verified information initially gathered by text-mining the literature. By integrating information from miRTarBase into HisCoM-mimi, a broad range of target information derived from the research literature can be analyzed. Another improvement of the new HisCoM-mimi approach is the inclusion of updated algorithms to provide the lasso and elastic-net penalties for users who want to fit a model with a smaller number of selected miRNAs and mRNAs. We expect that our HisCoM-mimi software will make advanced methods accessible to researchers who want to identify miRNA-mRNA interaction pairs related with binary phenotypes.

• English & American cultural studies
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• v.17 no.1
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• pp.27-54
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• 2017

Brian Ascalon Roley's American Son, one of the outstanding Filipino American novels after the LA riots, critically deals with a racial issue of his community which has been intermingled with the myth of model minority. Gabe and Thomas, considered as obedient Filipino younger immigrants, are asked to achieve the American dream as a way to place themselves at the center of the mainstream white society. However, they recognize that they cannot be accepted as a suitable subject for the invincible racism deeply rooted in the society. While Tomas refuses to become a model minority by identifying himself with the Mexican, Gabe is expected to become an idealistic subject of model minority by his mother since he complies with the rules of the mainstream society. However, he accepts his brother's violent way of life in that violence is necessary to protect his family from the racial discrimination in America. Though he is his mother's hope for model minority, he recognizes the only condition to achieve her expectation is the American society where there is no racism at all. However, by taking the case of Gabe and Thomas, Roley suggests that the younger generation of Filipino American immigrants have no choice but to accept violence to survive in the American society because racism always threatens their life.

• Asia pacific journal of information systems
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• v.33 no.4
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• pp.934-956
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• 2023

This study focuses on the adoption of Healthcare Information System (HIS) in India's healthcare services, which has led to an increased use of HIS software for managing patient information in hospitals. The study aims to evaluate the factors that influence hospital workers' satisfaction with HIS usage and its impact on their intention to continue in the use of HIS. Primary data was collected through a survey questionnaire from 265 hospital workers. A new framework was developed, and Structural Equation Modeling (SEM) was used for analysis. Sensitivity analysis was also conducted on demographic data using an Artificial Neural Network (ANN) approach. The results indicated that all hypotheses were significant (p < 0.05). Effort expectancy was the most significant factor influencing hospital workers' satisfaction (p < 0.01). Sensitivity analysis showed that education (Model-A) and experience in use of HIS (Model-B) were the most important factors. The study contributes by proposing a new theoretical framework and extending the previous research on HIS usage satisfaction. Overall, the study highlights the importance of easiness and usefulness in predicting HIS usage satisfaction.

• Genomics & Informatics
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• v.18 no.1
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• pp.11.1-11.3
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• 2020

In genome-wide association studies, pathway-based analysis has been widely performed to enhance interpretation of single-nucleotide polymorphism association results. We proposed a novel method of hierarchical structural component model (HisCoM) for pathway analysis of common variants (HisCoM for pathway analysis of common variants [HisCoM-PCA]) which was used to identify pathways associated with traits. HisCoM-PCA is based on principal component analysis (PCA) for dimensional reduction of single nucleotide polymorphisms in each gene, and the HisCoM for pathway analysis. In this study, we developed a HisCoM-PCA software for the hierarchical pathway analysis of common variants. HisCoM-PCA software has several features. Various principle component scores selection criteria in PCA step can be specified by users who want to summarize common variants at each gene-level by different threshold values. In addition, multiple public pathway databases and customized pathway information can be used to perform pathway analysis. We expect that HisCoM-PCA software will be useful for users to perform powerful pathway analysis.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.579-583
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• 2012

Background: The SULT1A1 Arg213His polymorphism is reported to be associated with lung cancer risk. However, this relationship remains controversial. For better understanding a meta-analysis was therefore performed. Methods: An extensive search was performed to identify all case-control studies investigating association between SULT1A1 Arg213His polymorphism and lung cancer risk. The strength was assessed by odds ratio (OR) with the corresponding 95% confidence interval (95%CI). Results: A total of five publications covering 1,669 cases and 1,890 controls were included in this meta-analysis. No significant association between SULT1A1 Arg213His polymorphism and lung cancer risk was observed in overall comparisons in all genetic models (dominant model: OR=1.33, 95%CI=1.00-1.76, P=0.05; additive model: OR=1.30, 95%CI=0.93-1.81, P=0.12; recessive model: OR=1.21, 95%CI=0.89-1.66, P=0.23). However, on subgroup analysis, an elevated risk in mixed populations with variant His allele was revealed in the dominant model (OR=1.66, 95% CI=1.06-2.62, P=0.03). Furthermore, the SULT1A1 Arg213His polymorphism was associated with an increased risk of lung cancer in both females and males in the dominant model (females: OR=1.72, 95%CI=1.29-2.27, P=0.00; males: OR=1.46, 95%CI=1.19-1.78, P=0.00). No significant association between this polymorphism and different smoking status (smokers and non-smokers) and the other ethnicities (Asians and Caucasians) was shown. Conclusions: The results of this meta-analysis indicate that the SULT1A1 Arg213His polymorphism is not associated with lung cancer risk in Asians and Caucasians, but possible elevation for genotype (GA/AA) in mixed populations and males and females needs further investigation.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.36
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• pp.111-140
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• 2007

This paper intends to review the qualifications of arbitrator, the disclosure of disqualifications by arbitrator, the challenge grounds of arbitrator, and the challenge procedure of arbitrator under the arbitration laws and rules. There are no provisions for the qualification of arbitrator in the UNCITRAL Model Law on International Commercial Arbitration. Under the UNCITRAL Model Law on person shall be precluded by reason of his nationality from acting as an arbitrators. Under the UNCITRAL Model Law when a person is approached in connection with his possible appointment as an arbitrator, he shall disclose any circumstances likely to give rise to justifiable doubts as to his impartiality or independence. An arbitrator, from the time of his appointment and throughout the arbitral proceedings, shall without delay disclose any such circumstances to the parties. Under the UNCITRAL Model Law an arbitrator may be challenged only if circumstances exist that give rise to justifiable doubts as to his impartiality or independence, or if he does not possess qualifications agreed to by the parties. Under the UNCITRAL Model Law the parties are free to agree on a procedure for challenge an arbitrator. Failing such agreement, a party who intends to challenge an arbitrator shall send a written statement of the reasons for the challenge to the arbitral tribunal within 15 days after becoming aware of the constitution of the arbitral tribunal or any circumstance that give rise to justifiable doubts as to his impartiality or independence. Unless the challenged arbitrator withdraws from his office or the other party agrees to the challenge, the arbitral tribunal shall decide on the challenge. In conclusion, an arbitrator has a responsibility not only to the parties but also to the process of arbitration, and must observe high standards of conduct so that the integrity and must observe high standards of conduct so that the integrity and fairness of the process will be preserved.

• Journal of Engineering Education Research
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• v.24 no.6
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• pp.67-78
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• 2021

This study is an analysis of the life of Max Planck (1858-1947), the in view of engineering literacy education. Some expressions describing Planck include "the father of German science", "the namer of Quantum". Furthermore, he is the scientist who permanently engraved his name in a scientific invariant called the Planck Constant. Planck had already made remarkable scientific achievements in his mid-ages, which became the springboard of quantum mechanics, but he went on to achieve much more in his old age. Between 1910s and 1930s, he was the director of the Kaiser-Wilhelm Gesellschaft, the Berlin Academy, and the German Physics Society, which is the German core research group. In the 1910s, he endured the terrible personal suffering of losing his three children and then succeeded in rebuilding German science in the 1920s in his golden age of 70s. His achievement was great not only as a scientist but also as a science administrator. His life was contradictory in several ways. While fundamentally being a conservative, he initiated a great scientific revolution. While making efforts to preserve traditional values, he was in the center of great many upheavals and destruction. While being the incarnation of honesty, he was also given to extremely delicate political positions. In his long career, Planck lived with all his might as a leader of the German science organizations and permanently left his name on the institute representing Germany. Planck succeeded in his work for the institutional development of science, philosophical understanding of science, and as a role model of exemplary scientist. His long life was accompanied by both achievements and failures, intangible and difficult to judge. Today, as research and development management and scientific leadership have become increasingly important, Planck's life may be a good example of engineering literacy education.

• Asia pacific journal of information systems
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• v.12 no.1
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• pp.45-65
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• 2002

Factors influencing the success or failure of information systems(IS) have been discussed in many literature. However, limited theoretical development or empirical research have examined the effectiveness of hospital information systems(HIS). This study set out the research model of influencing factors and the performance of HIS through theoretical studies based on Management Information Systems, and then empirically tested hypotheses related to the model. The model was tested using LISREL analysis on the sample of 274 respondents who have worked with the HIS. The major results of this study are as follows: First, system characteristics and organizational characteristics have a statistically significant influence on user satisfaction. Second, the hypothesis 3, proposing that computer self-efficacy would relate positively to user satisfaction, was not supported by the results, though. According to these results, system quality, information quality, service quality and support of top management are very important variables for IS success. The study's findings also indicate DeLone and McLean's model is correct in proposing that the indirect relationship between influencing factors and organizational effectiveness, mediated by user satisfaction, is an important one.

• Journal of Intelligence and Information Systems
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• v.12 no.4
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• pp.1-14
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• 2006

This study proposed a customer preference estimation model for production recommendation and a method to enhance the performance of product recommendation using the estimated customer preference information. That is, we suggested customer preference estimation model to estimate exactly customer's product preference with his behavior. This model shows the relationship of customer's behaviors with his preferences. The proposed estimation model is optimized by learning the relative weights of customer's behavior variables to have an effect on his preference and enables to estimate exactly his preference. To validate our proposed models, we collected virtual book store data and then made a comparative analysis of our proposed models and a benchmark model in terms of performance results of collaborative filtering for product recommendation. The benchmark model means a prior preference weighting model. The results of our empirical analysis showed that our proposed model performed better results than the benchmark model.