• 대한가정학회지
• /
• 제50권6호
• /
• pp.1-11
• /
• 2012

As the immigrant population is rapidly growing in South Korea, it is important for the next generation of Korean adolescents to foster unprejudiced attitudes towards immigrants. This paper thus seeks to shed light on adolescent prejudice towards immigrants, by addressing the following three questions: (1) Does a mother's prejudice towards immigrants and parenting style influence their adolescent children's prejudice towards immigrants? (2) Does an adolescent's prejudice towards immigrants influence his/her self-identity? (3) Does an adolescent's prejudice towards immigrants influence his/her coping styles? The sample consisted of 288 pairs of Korean adolescents and their mothers. According to hierarchical regression analyses, a mother's prejudice towards immigrants significantly predicted her adolescent's prejudice towards immigrants, after taking sociodemographic variables into account, whereas her parenting style did not. In addition, having a low level of prejudice towards immigrants among adolescents predicted high levels of self-identity (e.g. independence, proprioceptive, and mission orientation), and a greater use of positive coping skills (e.g. support-seeking and problem-solving). Overall, results showed that mothers played a significant role in shaping their adolescent's prejudice towards immigrants. Results also provided evidence that prejudice towards immigrants may interfere with the healthy development of self-identity and coping style during adolescence. In conclusion, this study suggests that multicultural education for adolescents can be more effective, when it is provided in partnership with a parent education program that is designed to raise parental multicultural awareness.

• Journal of Microbiology and Biotechnology
• /
• 제3권2호
• /
• pp.86-90
• /
• 1993

CMCase positive clones were screened from Cellulomonas sp. YE-5 and named pCE1, pCE2 and pCE3. Among the positive clones pCE1 was used for this study, because it has the smallest insert and the highest CMCase activity among the 3 clones, and its nucleotide sequence was determined. The CMCase gene in pCE1 was composed of 1071 bp of nucleotides coding 357 amino acids. Computer analysis showed that the pCE1 has 65% sequence homology with the endoglucanase from Cellulomonas fimi.

• 아동학회지
• /
• 제21권1호
• /
• pp.59-72
• /
• 2000

This study explored the contribution of mother's representation of her mother and father during early years, marital satisfaction, and husband's participation in child caring to mothers' parenting behaviors. The subjects were 253 middle-class mothers and fathers in Seoul who had 2-to 3-year-old children. The data were gathered through questionnaires developed for the current study. As predicted, marital satisfaction and husband support as well as early family experiences were significant variables in predicting positive mothering for mothers of young children. However, the most powerful predictor of mothers' parenting turned out to be marital satisfaction. It was noteworthy that mothers who experienced positive and secure relationships with their own mothers were actively involved/intimate with their children whereas mothers who had insecure relationships with their own fathers showed more authoritarian control over their children.

• 감성과학
• /
• 제24권2호
• /
• pp.75-80
• /
• 2021

Do happy applicants achieve more? Although it is well established that happiness predicts desirable work-related outcomes, previous findings were primarily obtained in social settings. In this study, we extended the scope of the "happiness premium" effect to the artificial intelligence (AI) context. Specifically, we examined whether an applicant's happiness signal captured using an AI system effectively predicts his/her objective performance. Data from 3,609 job applicants showed that verbally expressed happiness (frequency of positive words) during an AI interview predicts cognitive task scores, and this tendency was more pronounced among women than men. However, facially expressed happiness (frequency of smiling) recorded using AI could not predict the performance. Thus, when AI is involved in a hiring process, verbal rather than the facial cues of happiness provide a more valid marker for applicants' hiring chances.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권6호
• /
• pp.3711-3717
• /
• 2013

Background: To assess the efficacy and tolerability of Cisplatin plus Gemcitabine combination in patients with brain metastases (BM) from breast cancer (BC). Materials and Methods: Eighteen BC patients with BM who were treated with Cisplatin plus Gemcitabine regimen between 2003-2011 were evaluated. Results: A median of 6 cycles of this regimen were received, in fifteen patients (83.3%) as first-line chemotherapy, in 2 as second-line and in 1 as third-line after diagnosis of BM. Dose reduction was performed in 11 (61.1%) patients; major reasons were neutropenia and leukopenia. Grade III neutropenia and Grade II trombocytopenia rates were 33.3% and 16.7% respectively. Overall response rate (ORR; complete+partial response rate) was 33.4% (n=6) for the entire study population; triple negative patients achieved an 66.6% ORR while hormone receptor (HR) positive patients had 25% and HER2 positive patients 12.5%. Median progression-free survival was 5.6 months (2.4-8.8 months, 95%CI) and longer in patients with triple negative breast cancer (TNBC) (median 7.4 months, 95%CI, 2.4-12.3 months) than the patients with other subtypes (median 5 months for HER2 positive and 3.6 months for HR positive patients). Median PFS of the patients with TNBC who received this regimen as first-line was 9.2 months (5.2-13.2 months, 95%CI). Conclusions: Cisplatin plus Gemcitabine may be a treatment option for patients with BM from breast cancer. Longer PFS and higher response rates are results that support the usage of this regimen especially for the triple negative subtype. However, further prospective and randomized trials are clearly required to provide more exact information.

• Journal of Yeungnam Medical Science
• /
• 제8권1호
• /
• pp.215-219
• /
• 1991

저자들은 54세 여자에서 piroxicam 복용 후 일광노출부위에 광과민성 피부염이 발생한예를 경험하고 광검사 및 광첩포검사 결과 광알레르기성 피부염으로 사료되는 예를 문헌고찰과 함께 보고하는 바이다.

• 가정과삶의질연구
• /
• 제4권2호
• /
• pp.103-117
• /
• 1986

The purpose of this study is to provide the basic information for the improvement of housewives consciousness and satisfaction of household work by analyzing the data regarding the housewives consciousness and satisfaction toward household work. The research problems was described as follows; 1) How independent variables influence the housewives consciousness of household work. 2) How independent variables influence the satisfaction of household work. 3) How relate the housewives consciousness and the satisfaction of household work. The research was conducted on 354 housewives in Seoul during the end of January and the beginning of March, 1986. As for the measurement of the instrument, questionnaire with 46 items was made by investigator. The data were analyzed by frequency, percentage, mean and t-test, F-test, Scheffe-test, Pearson-r. The results were summarized as follows; 1) Among the independent variables, the ages of housewives, durations of marriage, psychologica satisfaction were variables to have influence on the housewives consciousness towark household work. 2) Among the independent variable,s the socio-economic status, durations of marriage, psychological satisfaction were variables to have influence on the satisfaction of household work. 3) There were strong positive correlationship between the housewives consciousness and the satisfaction of household work. As a result, it is necessary to minimize the repetition and the overload of house-hold chores through the rationalization of household work and also to divide householdwork properly to family members. We let the housewives feel that her ability can be obtained from the household work. Especially the housewives must have a clear and a high level of consciousness of the household work an expect to receive high value of her household work from the family members. In order to do so, it seems to be important that housewives makes on great effort to have a positive value system and attitudes toward the consciousness and satisfaction of household work. We also must develop those factors through school and home education.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권4호
• /
• pp.1471-1477
• /
• 2015

Background: Adding taxanes to adjuvant antracycline and cyclophosphamide (AC) in combination may provide significant improvement in node-positive and high risk node-negative breast cancer (BC) patients. However, the optimal dose and the role of dose-dense (DD) chemotherapy have yet to be determined. The aim of this study was to compare the efficacy of a DD paclitaxel (P)-AC combination with conventional weekly P-AC or docetaxel D-AC combinations in patients with node-positive breast cancer. Materials and Methods: Newly diagnosed 280 node-positive BC patients diagnosed from 1998 to 2013 in three clinics were retrospectively analyzed. Demographic and medical data were collected from the medical charts. Patients were categorized to 3 groups according to treatment arms: arm A, ddAC-P; arm B, weekly P and AC combination; and arm C; T and AC combination. Adjuvant trastuzumab was added for HER2-positive patients. Kaplan-Meier survival analysis was carried out for disease free survival (DFS) and overall survival (OS). The log-rank test was used to examine the statistical significance of the differences observed between the groups. Two-sided P values <0.05 were considered statistically significant. Results: Of the total of 280 patients, 101 were in arm A, 114 in arm B and 65 in arm C.The median ages were 49, 50 and 46, respectively (p=0.11). Median follow-up was 39 (3-193) months. Stage, lymphovascular and perineural invasion, receptor patern, and menopausal status were similar in the 3 treatment arms, but HER2 positivity was significantly lower in arm A, compared to arms B and C (25.7%, 53.1%, 41.5% in arms A, B and C, respectively; p<0.001). Also grade 3 tumors were significantly less frequent in treatment arm A compared to arm B and C (27.3%, 56.8% and 49.2%, respectively, p=0.01). Afterunivariate and multivariate analysis were performed, 3-year DFS rates were 89%, 81%, and 75%, respectively (p=0.12) and three year OS rates were 96.6%, 89%, and 75% (p=0.62). Conclusions: In this study, no significant difference was found between adjuvant dose dense and conventional taxane treatment regimens.

• 디지털콘텐츠학회 논문지
• /
• 제1권1호
• /
• pp.1-11
• /
• 2000

최근 인터넷상에서는 원격교육이나 온라인 교육에서 다양한 교육용 디지털 컨텐츠가 제공되고 있다. 특히 에듀테인먼트분야가 활성화되면서 흥미위주의 교육 컨텐츠가 많이 개발되고 있다. 하지만 컨텐츠가 적정기간($1{\sim}2$년) 동안 학습자가 흥미를 잃지 않고 스스로 학습하도록 유도하는가 라는 질적인 면에서 고려해 볼 때 부족한 면이 많다. 그러므로 학습자로부터 자발적이면서 적극적인 학습을 촉진시키기 위해서 학습자의 학습동기를 강화시키는 시스템이 필요하다. 본 논문은 후견인과 학습자가 제시한 목표의 성취도에 따라 보상을 제공하는 학습보상시스템 (LRS)을 설계 및 구현한다. LRS는 기존의 에듀테인먼트 컨텐츠를 활용하여 동시에 흥미와 보상을 함께 제공함으로써 교육효과증진을 목적으로 한다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권1호
• /
• pp.127-131
• /
• 2013

Trastuzumab is the first molecular targeting drug to increase the overall survival rate in advanced gastric cancer. However, it has also been found that a high intrinsic or primary trastuzumab resistance exists in some proportion of gastric cancer patients. In order to explore the mechanism of resistance to trastuzumab, firstly we investigated the expression of MUC1 (membrane-type mucin 1) in gastric cancer cells and its relationship with drug-resistance. Then using gene-silencing, we transfected a siRNA of MUC1 into drug-resistant cells. The results showed the MKN45 gastric cell line to be resistant to trastuzumab, mRNA and protein expression of MUC1 being significantly upregulated. After transfection of MUC1 siRNA, protein expression of MUC1 in MKN45cells was significantly reduced. Compared with the junk transfection and blank control groups, the sensitivity to trastuzumab under MUC1 siRNA conditions was significantly increased. These results imply that HER2-positive gastric cancer cell MKN45 is resistant to trastuzumab and this resistance can be cancelled by silencing expression of the MUC1 gene.