• Journal of Broadcast Engineering
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• v.22 no.4
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• pp.496-508
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• 2017

In this paper, we propose a Tone Mapping Operator (TMO) that preserves global contrast and precisely preserves boundary information. In order to reconstruct a High Dynamic Range (HDR) image to a Low Dynamic Range (LDR) display by using Threshold value vs. Intensity value (TVI) based on Human Visual System (HVS) and contrast value. As a result, the global contrast of the image can be preserved. In addition, by combining the boundary information detected using Guided Image Filtering (GIF) and the detected boundary information using the spatial masking of the Just Noticeable Difference (JND) model, And improved the perceived image quality of the output image. The conventional TMOs are classified into Global Tone Mapping (GTM) and Local Tone Mapping (LTM). GTM preserves global contrast, has the advantages of simple implementation and fast execution time, but it has a disadvantage in that the boundary information of the image is lost and the regional contrast is not preserved. On the other hand, the LTM preserves the local contrast and boundary information of the image well, but some areas are expressed unnatural like the occurrence of the halo artifact phenomenon in the boundary region, and the calculation complexity is higher than that of GTM. In this paper, we propose TMO which preserves global contrast and combines the merits of GTM and LTM to preserve boundary information of images. Experimental results show that the proposed tone mapping technique has superior performance in terms of cognitive quality.

• Progress in Medical Physics
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• v.11 no.2
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• pp.109-116
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• 2000

One consideration of radiation delivery in cervical cancer is the complication of critical organs, e.g., bladder and rectum. The absorbed dose of bladder and rectum in HDR intracavitary brachytherapy is measured indirectly with TLD dosimetry A method for the complication reduction of bladder and rectum is suggested. For two-hundred cervical cancer patients, follow-up MRI images were reviewed and distances from cervical central axis to bladder and rectum and vaginal wall thickness were measured. The sealed TLDs were placed upon the gauze packing of the ovoids and the distances to the TLDs from the ovoid center were measured in the simulation film and actual doses of bladder and rectum were calculated. From published data, maximal tolerance doses of bladder and rectum were derived and based on the permissible doses per fraction in HDR brachytherapy the packing thicknesses were determined in both directions. The required minimal packing thicknesses for bladder and rectum were 0.43 and 0.92 cm, respectively. The results were compared with computer calculation using the Meisberger polynomial approach. It is our hope this study can be used for a guideline for users in clinic in estimating critical organ dose in bladder and rectum in HDR brachytherapy in vivo dosimetry.

• Smart Structures and Systems
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• v.26 no.5
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• pp.575-589
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• 2020

For vibration control of stay cables in cable-stayed bridges, viscous dampers are frequently used, and they are regularly installed between the cable and the bridge deck. In practice, neoprene rubber bushings (or of other types) are also widely installed inside the cable guide pipe, mainly for reducing the bending stresses of the cable near its anchorages. Therefore, it is important to understand the effect of the bushings on the performance of the external damper. Besides, for long cables, external dampers installed at a single position near a cable end can no longer provide enough damping due to the sag effect and the limited installation distance. It is thus of interest to improve cable damping by additionally installing dampers inside the guide pipe. This paper hence studies the combined effects of an external damper and an internal damper (which can also model the bushings) on a stay cable. The internal damper is assumed to be a High Damping Rubber (HDR) damper, and the external damper is considered to be a viscous damper with intrinsic stiffness, and the cable sag is also considered. Both the cases when the two dampers are installed close to one cable end and respectively close to the two cable ends are studied. Asymptotic design formulas are derived for both cases considering that the dampers are close to the cable ends. It is shown that when the two dampers are placed close to different cable ends, their combined damping effects are approximately the sum of their separate contributions, regardless of small cable sag and damper intrinsic stiffness. When the two dampers are installed close to the same end, maximum damping that can be achieved by the external damper is generally degraded, regardless of properties of the HDR damper. Field tests on an existing cable-stayed bridge have further validated the influence of the internal damper on the performance of the external damper. The results suggest that the HDR is optimally placed in the guide pipe of the cable-pylon anchorage when installing viscous dampers at one position is insufficient. When an HDR damper or the bushing has to be installed near the external damper, their combined damping effects need to be evaluated using the presented methods.

• Journal of Applied Biological Chemistry
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• v.58 no.3
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• pp.273-279
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• 2015

Phaeodactylum tricornutum is a model diatom that its genomic information and biological tools are well established. In this study, a gene encoding (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (PtHDR), a terminal enzyme of the methylerythritol phosphate pathway regulating chlorophyll and carotenoid biosynthesis, was isolated from P. tricornutum. The isolated gene was cloned into pPha-T1 vector containing fcpA promoter to prepare pPha-T1-HDR plasmid. As a positive control, pPha-T1-eGFP plasmid was constructed with egfp gene. Stable nuclear transformation was carried out with these plasmids by particle bombardment method and zeocin resistant colonies of P. tricornutum were selected on f/2 agar plate. In result, transformation efficiency was evaluated according to the amount of plasmid DNA coated with gold particles. Integration of introduced plasmids was confirmed with genomic DNA of each transformant by polymerase chain reaction. The eGFP fluorescence was visible in the cytoplasm, indicating that eGFP was successively expressed in P. tricornutum system. The transcript level of exogenous Pthdr gene was evaluated with the obtained transformants. The results presented here demonstrated that introduction of Pthdr gene into P. tricornutum chromosome succeeded and expression of PtHDR was enhanced under the fcpA promoter.

• Radiation Oncology Journal
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• v.21 no.4
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• pp.276-282
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• 2003

Purpose: Although high-dose-rate intracavitary radiotherapy (HDR ICR) has been used in the treatment of cervical cancer, the potential for increased risk of late complication, most commonly in the rectum, is a major concern. We have previously reported on 136 patients treated with HDR brachytherapy between 1995 and 1999. The purpose of this study is to upgrade the previous data and confirm the correlation between late rectal complication and rectal dose in cervix cancer patients treated with HDR ICR. Materials and Methods: A retrospective analysis was peformed for 222 patients with cevix cancer who were treated for curative intent with external beam radiotherapy (EBRT) and HDR ICR from July 1995 to December 2001. The median dose of EBRT was 50.4 (30.6$\~$56.4) Gy with a daily fraction size 1.8 Gy. A total of six fractions of HDR ICR were given twice weekly with fraction size of 4 (3$\~$5.5) Gy to A point by Iridium-192 source. The rectal dose was calculated at the rectal reference point using the barium contrast criteria. in vivo measurement of the rectal dose was peformed with thermoluminescent dosimeter (TLD) during HDR ICR. The median follow-up period was 39 months, ranging from 6 to 90 months. Results: Twenty-one patients (9.5$\%$) experienced late rectal bleeding, from 3 to 44 months (median, 13 months) after the completion of RT. The calculated rectal doses were not different between the patients with rectal bleeding and those without, but the measured rectal doses were higher in the complicated patients. The differences of the measured ICR rectal fractional dose, ICR total rectal dose, and total rectal biologically equivalent dose (BED) were statistically significant. When the measured ICR total rectal dose was beyond 16 Gy, when the ratio of the measured rectal dose to A point dose was beyond 70$\%$, or when the measured rectal BED was over 110 Gy$_{3}$, a high possibility of late rectal complication was found. Conclusion: Late rectal complication was closely correlated with measured rectal dose by in vivo dosimetry using TLD during HDR ICR. If data from in vivo dosimetry shows any possibility of rectal bleeding, efforts should be made to reduce the rectal dose.

• Radioisotope journal
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• v.13 no.1
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• pp.64-67
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• 1998

• Broadcasting and Media Magazine
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• v.22 no.3
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• pp.48-59
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• 2017

• 대한방사선치료학회:학술대회논문집
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• 2001.06a
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• pp.8-9
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• 2001

• The Magazine of Kiice
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• v.5 no.2
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• pp.52-59
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• 2004

• The Magazine of the IEIE
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• v.41 no.10
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• pp.80-88
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• 2014