• Title/Summary/Keyword: HC_60

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Gel Type Formulation Utilizing Polymer-Surfactant Interaction (폴리머와 계면활성제의 상호작용을 이용한 젤타입 제형의 제조)

  • Kim, Dong-Joo;Kang, Tae-Jun;Lee, Cheon-Koo;Lee, Jung-No
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.33 no.1 s.60
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    • pp.7-10
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    • 2007
  • The interaction between polymers and surfactants was investigated by means of rheological and surface tension measurements. The polymers used in this study were acrylates/$C_{10-30}$ alkyl acrylate crosspolymer (AC) and ammonium acryloyldimethyltaurate/VP copolymer (AV). And the surfactants were PEG-40 hydrogenated castor oil (HC) and polysorbate 60 (P60). HC and P60 made the micelles intervening between AC polymers, resulting in the increase of viscosity. However, HC showed a similar behavior over the wider range of surfactant concentration than P60. Regarding of surface tensions in the same range of surfactant concentration, AC/HC solution showed the area of increasing surface tension with surfactant concentration in contrast to the AC/P60 solution showing no increasing area. It is assumed that the micelles between AC/HC were formed so cooperatively and strongly that the surfactants located at the surface originally moved to the micelles.

Cloning of the Polyhedrin Gene-Containing DNA Fragment of Hyphantria cunea Nuclear Polyhedrosis Virus (흰불나방 핵다각체바이러스 다각체단백질 유전자포함 절편의 클로닝)

  • 박호영;진병래;박순식;김정일;깅석권
    • Korean journal of applied entomology
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    • v.32 no.1
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    • pp.51-60
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    • 1993
  • The polyhedrin gene-containing DNA fragment of Hyphantria cunea nuclear polyhedrosis virus (HcNPV) was localized by southern hybridization with Autographa california CPA EcoRI-I fragment (7.3 kb), Bombyx mori NPV PatI-F fragment (7 kb) and synthetic oligonucleotide(30-mer) as probes. the PstI-L(5.3 kb) fragment of HcNPV was cloned to E. coli and the plasmid of the fragment was named as pHcP-L(8.0 kb). The pHcP-L was physically mapped and subcloned to E. coli as pHcP-L1(4.7 kb), pHcP-L2(7.1 kb), pHcP-L3(5.3 kb), pHcP-L4(4.2 kb) and pHcP-L5(4.5 kb).

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Spray Behavior Characteristics of Injector Used for HC-DeNOx Catalyst System in the Transparent Exhaust Manifold (모사 배기관 내 HC-DeNOx 촉매용 인젝터의 분무 거동 특성)

  • Lee, Dong-Hoon;Oh, Jung-Mo;Jeong, Hae-Young;Lee, Ki-Hyung;Yeo, Kwon-Gu
    • Transactions of the Korean Society of Automotive Engineers
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    • v.15 no.4
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    • pp.54-60
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    • 2007
  • A new method that optimizes a control of hydrocarbon (HC) addition to diesel exhaust gas for HC type DeNOx catalyst system has been developed. These catalysts are called as the HC-DeNOx catalyst in this paper. The system using HC-DeNOx catalyst requires a resonable quantity of hydrocarbons addition in the inlet gas of the catalyst, because the HC concentration in a diesel engine is so low that the HC is not sufficient for NOx conversion. Generally ambient temperature in the exhaust manifold is $250{\sim}350^{\circ}C$, so spray behavior in this case is different from that of any other condions. This research shows spray behavior of injected hydrocarbons in the transparent exhaust manifold.

Association Analysis of Myosin Heavy-chain Genes mRNA Transcription with the Corresponding Proteins Expression of Longissimus Muscle in Growing Pigs

  • Men, X.M.;Deng, B.;Tao, X.;Qi, K.K.;Xu, Zi Wei
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.4
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    • pp.457-463
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    • 2016
  • The goal of this work was to investigate the correlations between MyHC mRNA transcription and their corresponding protein expressions in porcine longissimus muscle (LM) during postnatal growth of pigs. Five DLY ($Duroc{\times}Landrace{\times}Yorkshire$) crossbred pigs were selected, slaughtered and sampled at postnatal 7, 30, 60, 120, and 180 days, respectively. Each muscle was subjected to quantity MyHCs protein contents through an indirect enzyme-linked immunosorbent assay (ELISA), to quantity myosin heavy-chains (MyHCs) mRNA abundances using real-time polymerase chain reaction. We calculated the proportion (%) of each MyHC to total of four MyHC for two levels, respectively. Moreover, the activities of several key energy metabolism enzymes were determined in LM. The result showed that mRNA transcription and protein expression of MyHC I, IIa, IIx and IIb in LM all presented some obvious changes with postnatal aging of pigs, especially at the early stage after birth, and their mRNA transcriptions were easy to be influenced than their protein expressions. The relative proportion of each MyHC mRNA was significantly positively related to that of its corresponding protein (p<0.01), and MyHC I mRNA proportion was positively correlated with creatine kinase (CK), succinate dehydrogenase (SDH), malate dehydrogenase (MDH) activities (p<0.05). These data suggested that MyHC mRNA transcription can be used to reflect MyHC expression, metabolism property and adaptive plasticity of porcine skeletal muscles, and MyHC mRNA composition could be a molecular index reflecting muscle fiber type characteristics.

The Current State of Hospital-based Home Care Services in Korea: Analysis of Data on Insurance Claims for Home Care from 2007 to 2012 (의료기관 가정간호의 현황(2007-2012): 가정간호 급여청구자료 분석)

  • Song, Chong Rye;Lee, Mi Kyoung;Hwang, Moon Sook;Yoon, Young Mi
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.21 no.2
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    • pp.127-138
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    • 2014
  • Purpose: The objectives of this study were to analyze the state of hospital-based home care (HC) services annually and to provide basic information for research and policy regarding home care. Methods: This study is a secondary analysis of the yearly state of HC services from the Health Insurance Review & Assessment Services from 2007 to 2012. Results: The decreased by 34.6%, from 214 agencies in 2007 to 140 in 2012. The annual average number of active home care nurses was 440, which included 6.7% of the licensed home care nurses until 2012. The annual average number of HC patients were 32,000, and this number decreased by 21% in 2012, compared to that of 2008. Of the HC patients, about 70% were over 60 years of age. The chronic diseases among HC patients have been decreasing steadily since 2007. Seventy to eighty percent of the home visits were made in general hospitals or higher level hospitals. The total medical cost for HC services was 21 billion won in 2007, which consisted of 0.06% of the national medical costs, and it was 22 billion won and 0.03% in 2012. Conclusion: Based on the results of this study, further research on HC services is necessary to frame policies for the expansion of HC agencies.

A Study the Health Problems of the Living-alone Elderly Using MDS-HC 2.0 (MDS-HC 2.0을 이용한 일부 독거노인의 건강문제 조사연구)

  • Park, Kyung-Min;Jaung, Ae-Hwa
    • Research in Community and Public Health Nursing
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    • v.17 no.1
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    • pp.74-82
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    • 2006
  • Purpose: This study used MDS-HC 2.0 to identify health problems in the elderly who live alone. Method: The subjects of this study were 100 living-alone elders aged over 65 in Daegu city. This study was performed through home visiting interviews during the period from the 1st of September to the 30th of September 2005. Analysis in this study was made using SPSS Version 11.0. Results: Frequent health problems in the living-alone elderly were: preventive heath measure (90), health promotion (80), social function (78), visual function (75), depression and anxiety (61), pain and communication disorder (60), cognition (55), environmental assessment (48) and oral health (45) in order of frequency. Informal services were provided to 73% of the subjects for emotional support. IADL services were provided to 57% of the subjects, and ADL services to 66%. Conclusion: Nursing intervention programs based on health problems from MDS-HC 2.0 should be provided in order to cope with individual health problems and living-alone elders needs. The results of this study suggest that MDS-HC 2.0 is applicable to help decide nursing interventions for the elderly who live alone in community.

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Effects of Unripe Rubus coreanus Miquel Extract on Improvement of Lipid Metabolism in C57BL/6 Mice Fed a High-Cholesterol Diet (미숙과 복분자 열매 추출물이 고콜레스테롤 식이를 섭취시킨 C57BL/6 Mice의 지질대사 개선 효과)

  • Jung, Myung-A;Cho, Sook-Hyun;Lee, Sun Young;Kim, Ji Hye;Oh, Kyonyeo;Kim, Young-Suk;Yoo, GooSang;Lee, Dong-Wook;Kim, Sunoh
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.5
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    • pp.650-655
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    • 2014
  • Hypercholesterolemia is the presence of high levels of cholesterol in the blood, and it is regarded as a risk factor for cardiovascular disease due to the effects of cholesterol. The objective of this study was to investigate the effects of unripe Rubus coreanus Miquel (uRC) extract on lipid metabolism in hypercholesterolemic mice fed a high cholesterol diet (HC). uRC 50 (unripe R. coreanus 5% ethanol extract 50 mg/kg/day), uRC 100 (unripe R. coreanus 5% ethanol extract 100 mg/kg/day), uRC 300 (unripe R. coreanus 5% ethanol extract 300 mg/kg/day), and BO (borage seed oil containing minimum of 20% ${\gamma}$-linolenic acid 30 mg/kg/day) were orally administered for 60 days after HC. Oral administration of uRC 50, uRC 100, uRC 300, and BO significantly reduced serum total-cholesterol, triglyceride, LDL-cholesterol, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, atherogenic index, and cardiac risk factor levels. Similarly, uRC treatment elevated serum HDL-cholesterol levels. These results suggest that unripe R. coreanus extract could be established as a functional food for the improvement of lipid metabolism.

Characteristics and Action Pattern of Alkaline Protease from Streptomyces gviseus HC-1141 (Streptomyces griseus HC-1141이 생성하는 Alkaline Protease의 특성 및 작용양상)

  • Choi, Cheong;Chung, Yung-Gun;Sung, Sam-Kyung;Choi, Kwang-Soo;Lee, Jae-Sung;Cho, Young-Je;Chun, Sung-Sook
    • Microbiology and Biotechnology Letters
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    • v.20 no.3
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    • pp.295-301
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    • 1992
  • An alkaline protease producing microorganism was isolated from soil and identified as Streptomyces griseus HC-1141. The optimum pH and temperature for the purified enzyme activity were 8.0 and $60^{\circ}C$, respectively. The enzyme was relatively stable in the pH range of 7.0-9.0 and at the temperature below $60^{\circ}C$. The activity of purified enzyme was inhibited by $Hg^{2+}$, $Cu^{2+}$, $Zn^{2+}$, $Ba^{2+}$ and $Fe^{2+}$, whereas activated by $Mn^{2+}$ and $Ca^{2+}$. $\varepsilon$-Amino caproic acid, 2,4-dinitrophenol and iodine did not show inhibitory effect on the activity of alkaline protease, but p-chloromercuribenzoic acid, ethylendiaminetetraacetic acid showed inhibitory effect on the enzyme activity. These result suggested that the protease was metalloenzyme, and require a reactive SH group for the activity. The reaction of this enzyme follows typical Michaelis-Menten kinetics with the $K_m$ value of $2.229{\times}10^{-4}$M and the $V_{max}$ of $46.08 {\mu}$g/min for casein. The activation energy for the alkaline protease calculated by Arrhenius equation was 3.643 kcal/mol. This enzyme hydrolyzed casein more rapidly than the hemoglobin and egg albumin.

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Population-based Cervical Cancer Screening Using High-risk HPV DNA Test and Liquid-based Cytology in Northern Thailand

  • Siriaunkgul, Sumalee;Settakorn, Jongkolnee;Sukpan, Kornkanok;Srisomboon, Jatupol;Suprasert, Prapaporn;Kasatpibal, Nongyao;Khunamornpong, Surapan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6837-6842
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    • 2014
  • Background: Northern Thailand is a region with a high cervical cancer incidence. Combined high-risk HPV (hrHPV) DNA testing and cytology (co-testing) has increasingly gained acceptance for cervical cancer screening. However, to our knowledge, data from a population-based screening using co-testing have not been available in this region. This study therefore aimed to evaluate the performance of cytology and hrHPV test in women in northern Thailand. Materials and Methods: Cervical samples were collected for hybrid capture 2 (HC2) testing and liquid-based cytology from women aged 30 to 60 years who were residents in 3 prefectures of Chiang Mai in northern Thailand between May and September 2011. Women with positive cytology were referred to colposcopy, while women with positive for HC2 only were followed for 2 years. Results: Of 2,752 women included in this study, 3.0% were positive in both tests, 4.1% for HC2 only, and 1.3% had positive cytology only. At baseline screening, positive HC2 was observed in 70.6% among cytology-positive women compared with 4.3% among cytology-negative women. The prevalence of positive HC2 or cytology peaked in the age group 35-39 years and was lowest in the age group 55-60 years. High-grade squamous intraepithelial lesion or worse lesions (HSIL+) were histologically detected in 23.5% of women with positive baseline cytology and in 9.8% of women with positive baseline HC2 only on follow-up. All women with histologic HSIL+ had positive baseline HC2. Conclusions: The hrHPV test is superior to cytology in the early detection of high-grade cervical epithelial lesions. In this study, the prevalence of histologic HSIL+ on follow-up of women with positive hrHPV test was rather high, and these women should be kept under careful surveillance. In northern Thailand, hrHPV testing has a potential to be used as a primary screening test for cervical cancer with cytology applied as a triage test.