• 대한세포병리학회지
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• 제19권2호
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• pp.119-125
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• 2008

This study was performed to compare the efficacy between a DNA chip method and a Hybrid-Capture II assay (HC-II) for detecting human papillomavirus in patients with intraepithelial lesions of the uterine cervix. From May, 2005, to June, 2006, 192 patients with abnormal colposcopic findings received cervical cytology, HC-II and HPV DNA chip tests, and colposcopic biopsy or conization. We compared the results of HC-II and HPV DNA chip in conjunction with liquid based cervical cytology (LBCC) and confirmed the results of biopsy or conization. The sensitivity of the HPV DNA chip test was higher than HC-II or LBCC. The HPV DNA chip in conjunction with LBCC showed higher sensitivity than any single method and higher sensitivity than HC-II with LBCC. We confirmed that the HPV DNA chip test was more sensitive for detecting HPV in cervical lesions than HC-II, and that it would provide more useful clinical information about HPV type and its multiple infections.

• 대한임상검사과학회지
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• 제47권3호
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• pp.132-139
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• 2015

최근 $p16^{INK4a}$/Ki-67 이중면역염색은 액상세포검사에서 자궁경부 이형성증과 암을 조기에 발견하기 위한 새로운 생체 표지자로 대두되고 있다. 저자들은 자궁경부질도말의 액상세포검체 총 109례에서 CINtec$^{(R)}$ PLUS kit를 사용하여 $p16^{INK4a}$/Ki-67 이중면역염색을 시행하였고, 그 결과를 액상세포검사, HPV hybrid capture II (HC II) 검사 그리고 조직학적 진단과 서로 비교하였다. $p16^{INK4a}$/Ki-67 양성 발현은 세포학적 진단에서 저등급 편평상피내병변 이상의 증례 그리고 조직학적 진단에서 자궁경부 상피내종양 1등급 이상의 증례에서 유의미하게 높았다. 액상세포검사상 비정형 편평 상피세포 소견을 보이는 46례 중, 31례 (67.4%)가 $p16^{INK4a}$과 Ki-67 양성 소견을 보였고, 이러한 양성 증례들은 조직검사에서도 대부분 자궁경부 상피내종양 1등급 이상의 병변에 해당하였다. 자궁경부 상피내종양 1등급 이상의 병변을 발견하기 위한 $p16^{INK4a}$/Ki-67 이중면역염색의 민감도는 액상세포검사보다 높은 89.0%였고, 특이도는 73.5%로 HC II 검사보다 높게 분석되었다. 따라서, $p16^{INK4a}$/Ki-67 이중면역염색 방법은 액상세포검사법의 민감도와 HC II 검사법의 특이도를 보완하기 위한 진단적 검사로 유용하다고 할 수 있다.

• 한국콘텐츠학회논문지
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• 제13권8호
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• pp.308-313
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• 2013

세포선별검사에서 ASCUS로 진단된 검체 중 F-UP이 진행되지 않은 검체 179건을 대상으로 HPV high risk factor, low risk factor를 확인하기 위해서 Hybrid Capture II Test를 하였다. 시험 결과 high risk factor 양성 및 low risk factor 양성은 전체 179 cases 중 26 cases로 나타났으며, 전체 검체 중 약 15%에 해당되었다. 또한 전체 15%의 양성검체 중 high risk factor 양성은 96%에 해당되는 것을 확인하였다. 결론적으로 효과적인 검진 체계를 갖춘 나라에서도 자궁경부암의 예방이 완전히 해결되지 않고 있는 문제점이 있는 여건을 고려해 볼 때 추적 관찰이 용이하지 않은 경우를 대비해 자궁경부암으로 진행될 수 있는 precancerous lesion의 원인 인자인 HPV 존재 유무를 세포선별검사와 HPV Hybrid Capture II Test를 동시에 시행하는 것이 효과적이라고 사료된다.

• 한국지하수토양환경학회지:지하수토양환경
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• 제25권1호
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• pp.95-105
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• 2020

In this study, iron nanoparticles impregnated hydrochar (FeNPs@HC) was synthesized using lignocellulosic waste and simple one-pot synthetic method. During hydrothermal carbonization (HTC) process, the mixture of lignocellulosic waste and ferric nitrate (0.1~0.5 M) as a precursor of iron nanoparticles was added and heated to 220℃ for 3 h in a teflon sealed autoclave, followed by calcination at 600℃ in N₂ atmosphere for 1 h. For the characterization of the as-prepared materials, X-ray diffraction (XRD), cation exchange capacity (CEC), fourier transform infrared spectrometer (FT-IR), Brunauer-Emmett-Teller (BET), transmission electron microscope (TEM), Energy Dispersive X-ray Spectroscopy (EDS) were used. The change of Fe(III) concentration in the feedstock influenced characteristics of produced FeNPs@HC and removal efficiency towards As(V) and Pb(II). According to the Langmuir isotherm test, maximum As(V) and Pb(II) adsorption capacity of Fe_0.25NPs@HC were found to be 11.81 and 116.28 mg/g respectively. The results of this study suggest that FeNPs@HC can be potentially used as an adsorbent or soil amendment for remediation of groundwater or soil contaminated with arsenic and cation heavy metals.

• Asian Pacific Journal of Cancer Prevention
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• 제15권11호
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• pp.4465-4466
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• 2014

HPV type-specific detection may promote cervical screening program and vaccination development worldwide. We conduct a study comparing HPV Hybrid capture II (HC II) Test and Hybribio GenoArray test, a newly developed HPV type-specific assay, in patients with cervical epithelial neoplasm. Results showed a good concordance in cervical HPV detection between two tests (kappa value 0.80, p<0.05, McNemar test). Our study may promote utilization of type-specific HPV detection that is helpful for cervical cancer screening and vaccination.

• Restorative Dentistry and Endodontics
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• 제34권3호
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• pp.208-214
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• 2009

이 연구의 목적은 서로 다른 두 개의 근관 크기(#70, #120)를 가진 레진 모형에 MTA (minoral trioxide aggregate)를 서로 다른 두 가지 방법 (수기구 충전(HC), 초음파 보조 수기구 충전(UAHC))으로 정방위 충전하고 MTA apical plug의 미세 누출을 평가하는 것이다. 직선형 근관 형태를 가지며, #70과 #120의 치근단 크기를 갖는 레진 모형을 각각 30개씩 준비하였다. 이 시편들을 MTA의 적용 방법에 따라 각 군을 2개의 아군으로 다음과 같이 분류하였다 (n=15); C70: HC + 치근단 크기 #70, C120: HC + 치근단 크기 #120, U70: UAHC + 치근단 크기 #70, U120: UAHC + 치근단 크기 #120. MTA 충전을 완료한 후에, 24시간 동안 실온에서 100% 습도를 유지하여 경화시켰다. 근관의 상부는 열연화 충전 시스템(Obtura II)을 이용하여 충전하였다. 48시간 동안 100% 습도를 유지하여 실온에서 0.2% rhodamine B 용액을 이용해 미세누출 실험을 하였다. 이 연구결과 #70의 치근단 크기를 갖는 그룹 사이에서 UAHC가 HC에 비해 미세누출이 적은 것으로 나타났다(p<0.05). 이 연구 조건하에서는 초음파 진동을 동반한 정방위 MTA apical plug 형성 방법이, 특히 좁은 근관에서 더 효율적인 것으로 사료된다.

• 동력기계공학회지
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• 제14권2호
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• pp.12-15
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• 2010

It is requested to shorten the starting duration for idle stop function equipped cars without harmful effects on the environment. Higher cranking speeds can be achieved with high torque starter. The object of this study is to develope the high torque starter and evaluate its effect on the exhaust emissions. The test was conducted on a 1.5 L, 4-cylinder, 16 valve, multipoint-port-fuel-injection gasoline engine. Engine out emissions such as HC, CO, $CO_2$, and the excess air ratios, lambda were measured using MEXA-554JK. The result showed that a high torque starter, HTS-II shortened the starting duration and reduced engine out emissions of HC, CO and improved starting performance with larger excess air ratio than that of the original starter, Org. S and a high torque starter, HTS-I.

• Restorative Dentistry and Endodontics
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• 제26권6호
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• pp.492-498
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• 2001

The purpose of this study was to evaluate four different composite resins in vitro for microleakage in Class II box type restorations that have gingival margins apical to the cementoenamel junction. Forty caries free extracted human molars were used in this study. The Class II cavities were prepared 1.0mm below cementoenamel junction with a #701 carbide bur. The teeth were randomly divided into four groups, each group comprising 20 treated cavities according to adhesives and filling materials ; Group 1: Scotchbond Multipurpose/Z 100. Group 2: Ariston Liner/Ariston pHc, Group 3: One Step/Pyramid, Group 4: Prime & Bond NT/SureFil. To simulate the clinical situation during restoration placement, a restoration template was fabricated and composite resin was filled using a three sited light-curing incremental technique. The specimens were stored in the 100% humidity for 7 days prior to thermocycling. The specimens were immersed in 2% methylene blue dye solution for 24 hours and then embeded in transparent acrylic resin and sectioned mesiodistally with a diamond wheel saw. The degree of marginal leakage was scored under the stereomicroscope($\times$20) and the data were analyzed by Kruskal Wallis test and Mann Whitney test. (omitted)

• 오토저널
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• 제15권3호
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• pp.47-54
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• 1993

This paper describes briefly the effect of ultrasonic fuel supply device on the performance of four stroke cycle gasoline engine. Experiments were carried out to clarify the effect of ultrasonic fuel supply device on the engine output, traveling fuel consumption ratio, exhaust emissions. The results were obtained as follows: 1.Engine output was increased 9-14% in comparison with that of the conventional injector. 2.Travelling fuel consumption ratio was improved 17-29% in comparison with that of the conventional injector. 3. CO, HC exhaust emissions was decreased compared to the value of the conventional injector. 4.Fuel consumption ratio in highway driving test was improved about 10% in comparison with that of the conventional injector.

• 보건교육건강증진학회지
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• 제27권1호
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• pp.1-8
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• 2010

Objectives: Human papillomavirus (HPV) infection is highly associated with cervical cancer. So, the modification of the risk factors of HPV infection is essential for prevention of cervical cancer. This study was performed to evaluate the risk factors of HPV infection. Methods: HPV test of 12,337 study population conducted using Hybrid-Capture II assay(HC-II) and self-administered questionnaires were collected. The study population was people who visited hospital-based medical screening center from January to December 2007 and all were female employees or employees' partner. Results: In logistic regression analysis, smoking and alcohol drinking were significant factors, with odds ratios of 1.328 (95% CI 1.010~1.746) and 1.644 (95% CI 1.309~2.066), respectively. Nutritional supplements was also significant factor, which odds ratio was 1.161 (95% CI 1.004~1.343). Oral contraceptives was positive association with HPV infection (odds ratio 2.108; 95% CI 1.217~3.652), whereas condom was negative association (odds ratio 0.851; 95% CI 0.740~0.979). Conclusion: HPV Prevalence of 12,377 study population was 11.4%. Smoking, alcohol drinking, nutritional supplements and oral contraceptives were possible risk factors of HPV infection, and condom had possible preventive effect on HPV infection. Further prospective and comprehensive studies about HPV risk factors are required.