• Title/Summary/Keyword: HBC

Search Result 88, Processing Time 0.027 seconds

Color evolution of HBC 722 in the post-outburst phase

  • Baek, Giseon;Pak, Soojong;Green, Joel D.;Lee, Jeong-Eun;Bae, Kyoung Min;Jeon, Yiseul;Choi, Changsu;Im, Myungshin;Meschiari, Stefano
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.38 no.2
    • /
    • pp.70.2-70.2
    • /
    • 2013
  • We present collections of optical photometry for a pre-main sequence star HBC 722. It showed large amplitude optical outburst (${\Delta}V=4.7$ mag) in 2010 and classified as a FU Orionis type object. We have been observing HBC 722 from 2011 April to 2013 May, using Camera for QUasars in EArly uNiverse (CQUEAN) attached to the 2.1 m Otto Struve telescope at the McDonald Observatory. Time-series monitoring data (minute-scale interval) were obtained in SDSS r, i and z bands to see short-scale behaviors as well as trace the long-term brightness changes after the eruption in 2010. Interestingly, it started to brighten from 2011 early summer and became brighter than the first outburst peak in our 2013 May observation. We expect that the recovering phase would result from re-increase of disk accretion rate, might attribute to distinctive short-scale color features. In this presentation, we report long- and short-timescale optical behaviors of HBC 722 in the post-outburst phase.

  • PDF

Role of pre-C Region in the Expression and Secretion of Hepatitis B Viral Core Antigen in Yeast (효모에서 B형 간염바이러스의 내면항원의 발현과 분비에 미치는 전위내면항원의 역할)

  • 신상훈;김성기;노현모
    • Korean Journal of Microbiology
    • /
    • v.28 no.1
    • /
    • pp.1-5
    • /
    • 1990
  • The coding sequence of hepatitis B viral core antigen (HBcAg) (subtype adr) contains two in-phase initiation codons, one for precore and the other for core antigen gene. To study the expression of core antigen and the role of precore region, the coding sequence of HBcAg with or without precore (pre-C) region were subcloned into yeast expression vector containing phosphoglycerate kinase (PGK) promoter. To study the role of upstream region in the expression of the core antigen, a series of 5' deletion mutants were also subcloned into the vector. After transformation into various host strains, the expression of HBcAg were analysed by radio-immunoassat. Under optimal condition of core antigen gene expression in yeast, the highest amount of antigen was detected in the cell line SHY4 containing pGKHBc plasmid composed of the yeast PGK gene promoter, terminator and C-gene. Regardless of the presence of precore region, core antigen was not detected in the medium but in cell extract. These results suggest that precore region cannot affect the secretion of core antigen in Saccharomyces cerevisiae.

  • PDF

Hydration Heat and Shrinkage of Concrete Using Hwangtoh Binder (황토결합재를 이용한 콘크리트의 수화열과 수축특성)

  • Kang, Sung-Soo;Lee, Seong-Lo;Hwang, Hey-Zoo;Cho, Min-Chol
    • Journal of the Korea Concrete Institute
    • /
    • v.20 no.5
    • /
    • pp.549-555
    • /
    • 2008
  • In this paper, the applicability of Hwangtoh, as an alternative of cement paste, is investigated for the solution of internal heat and shrinkage caused by the hydration of cement paste. Several small-sized specimens of Hwangtoh and ordinary portland concrete (OPC) were compared as to compressive strength, heat of hydration, and shrinkage strain. Moreover, the applicability to the construction structures was reviewed through the test of large-size specimens. The 28-day compressive strength of Hwangtoh concrete (HBC), ranged 18 to 33 MPa, can reach that of OPC. Not only the maximun internal temperature of HBC was read about 1/4 of OPC as it is cured, but also its shrinkage decreased more than the OPC did. Therefore, Hwangtoh binder is more favorable than cement binder in terms of its hydration heat and shrinkage under the construction of concrete.

Overexpression of HER-2/neu in Malignant Mammary Tumors: Translation of Clinicopathological Features from Dog to Human

  • Muhammadnejad, Ahad;Keyhani, Elahe;Mortazavi, Pejman;Behjati, Farkhondeh;Haghdoost, Iraj Sohrabi
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.12
    • /
    • pp.6415-6421
    • /
    • 2012
  • Background: Canine mammary gland tumors (CMGTs) are the most common tumor found in bitches. Changes in HER-2/neu genes in human breast cancer (HBC) lead to decrease in disease-free survival (DFS) and overall survival rate (OSR). Previous studies have demonstrated that the biological behavior of malignant mammary gland tumors (MMGTs) is similar to that of HBC. The present study aimed at evaluating the relationship between overexpression of HER-2/neu and clinicopathological features in MMGTs to represent a model of prognostic factors for HBC. Materials and Method: The clinicopathological data of 35 MMGTs were obtained. Immunohistochemical staining with HER-2, Ki-67 and CD34 markers was conducted with sections from paraffin-embedded blocks. According to standard protocols, histological type, grade, margin status, lymphovascular invasion (LVI), HER-2/neu score, proliferation rate and microvessel density (MVD) of tumors were determined and the association of HER-2/neu overexpression with these parameters was assessed statistically. Results: The IHC results showed that 12 (34.3%) cases were HER-2/neu positive. Statistical analyses indicated a significant relationship between HER-2 positivity and tumor grade (p=0.043), which also was demonstrated with cancer stage (p=0.035), tumor margin involvement (p=0.016), proliferation index (p=0.001) and MVD (p=0.001); however, there was no statistical relationship between LVI and tumor size. Overexpression of the HER-2/neu gene in MMGTs results in similar biological behavior as that of HBC; as a result, these tumors have can be considered to have important similarities in clinicopathological characteristics. Conclusions: MMGTs can be regarded as an HBC animal model. Further studies in this field would result in new treatments that could be beneficial for both dogs and humans.

Removal characteristic on micropollutants as ibuprofen, acetaminophen, caffeine in small water fall system using HBC ring media (생물막 끈상여재를 이용한 낙차형태별 수중 미량유해물질 ibuprofen, acetaminophen, caffeine분해특성)

  • Dockko, Seok
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.23 no.1
    • /
    • pp.129-135
    • /
    • 2009
  • PPCP (pharmaceuticals and personal care products) is known as micropollutant that is released from wastewater treatment plant. Research represents that these contaminants have increased in the last 10 years. This study tries to make four different trickling filter systems using plastic fiber media to remove PPCP such as acetaminophen, ibuprofen, caffeine. The results of the experiment that compares the process efficiencies of four different systems (A, B, C and D) using HBC media show that almost all the reactor has around 95% removal efficiency. Slope type HBC reactor has twice higher efficiency rather than submerged type reactor to remove PPCP in water system. In 8 hours, 89% of acetaminophen, ibuprofen, caffeine are removed in slope type reactor while 39% of them in submerged type.

HBC 722, A New FU Orionis-like Burst

  • Seong, Hyeon-Il;Lee, Jeong-Eun;Lee, Sang-Gak;Gang, Won-Seok;Lee, Byeong-Cheol;Seong, Hwan-Gyeong;Yang, Yun-A;Park, Geun-Hong;Jeon, Yeong-Beom;Lee, Hye-Ran
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.36 no.1
    • /
    • pp.81.2-81.2
    • /
    • 2011
  • 별 생성 과정은 코어라 불리는 고밀도의 분자운이 중력붕괴를 일으켜, 코어의 물질이 원반을 거쳐 원시성으로 유입되는 과정이다. 최근 들어, 원시성으로의 물질 유입량이 시간에 따라 일정하지 않으리라는 것이 일반적으로 받아들여지고 있으며, FU orionis에서 일어났던 accretion burst가 그 하나의 증거로 제시되고 있다. 지난 9월, 또 하나의 FU orionis-type burst가 HBC 722라 불리는 한 young stellar object에서 일어났다. 이 accretion burst로 인해 HBC 722는 V등급에서 4등급 밝아졌으며, 현재 서서히 어두워져 가고 있다. 우리는 지난 11월 말부터 4차례의 BOES 관측을 이 천체에 대해 수행하였고, 그 결과를 발표하고자 한다.

  • PDF

Effect of Herb and Bio-ceramic Complex Supplementation on Growth Performance and Meat Quality Characteristics in Finishing Pigs (한방부산물과 바이오 세라믹(약돌) 혼합물의 급여가 비육돈의 성장 및 육질 특성에 미치는 영향)

  • Cho Jin-Ho;Kwon Oh-Suk;Min Byoung-Joon;Son Kyoung-Seung;Chen Ying-Jie;Hong Jong-Wook;Kang Dea-Kyung;Kim In-Ho
    • Food Science of Animal Resources
    • /
    • v.24 no.4
    • /
    • pp.329-334
    • /
    • 2004
  • The objective of this study was to determine the effect of herb and bio ceramic complex supplementation on growth performance and meat quality characteristics in finishing pigs. Seventy-two crossbred (Landrace ${\times}$ Yorkshire ${\times}$ Duroc) pigs (78.98kg average initial body weight) were used in a 45 days growth assay. Dietary treatments included 1) Control (basal diet). 2) HBC (Herb and bioceramic complex) 0.1 (basal diet + 0.1% Herb and bioceramic complex) and 3) HBC 0.2 (basal diet +0.2% Herb and bioceramic complex). For overall period, ADG (Average Daily weight Gain), ADFI (Average Daily feed Intake) and ADG/ADFI increased in Control with no significant difference (p>0.05). Backfat thickness was not significantly different among the treatments (p>0.05). The total cholesterol, HDL (High Density Lipoprotein) cholesterol, LDL (Low Density Lipoprotein) cholesterol, LDL + VLDL (Very Low Density Lipoprotein) cholesterol, Triglyceride and Atherogenic index concentrations of serum in pigs fed HBC 0.2 diet were lower than those of pigs fed Control and HBC 0.1 diets without significant difference (p>0.05). L$\^$*/-, a$\^$*/-, and b$\^$*/- values of M. longissimus dorsi muscle were not significantly different among the treatments (p>0.05). The pH of pigs fed HBC 0.2 diet was significantly lower than that of pigs fed Control and HBC 0.1 diets (p<0.05). In conclusion, growth performance, cholesterol concentration in serum and meat quality were not affected by supplemental herb and bioceramic complex.