• Korean Journal of Organic Agriculture
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• v.19 no.spc
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• pp.222-224
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• 2011

The effects of seawater on growth of lettuce(Lactuca sativa L.), leaf perilla(Perilla frutescens var. japonica Hara), red pepper(Capsicum annuum L.) and cucumber(Cucumis sativus L.) seedlings were investigated in the glass greenhouse. These effects were studied on seedlings, and diluted seawater (1%, 5%, 10%, 20%, 50%, 100% v/v) was sprayed enough on leaves. The tested four vegetable crops have well grown up to 10% diluted seawater, but the tested vegetable crops were damaged from increasing salt levels. Of these, lettuce was provided salt-tolerant vegetable crop and red pepper was considered salt-sensitive vegetable crop. The salt tolerance of vegetable crops is different between crops and complicated because of additional detrimental effects caused by accumulated ions or specific ion toxicities in their leaves. These results show that agricultural use of seawater may be benefit crop cultivation in organic farming system as well as in conventional farming system.

• International Journal of High-Rise Buildings
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• v.8 no.3
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• pp.229-234
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• 2019

This report introduces the structural design of Hibiya Mitsui Tower built in Tokyo Midtown Hibiya. The upper part of this tower is used for offices and the lower portion is for commercial facilities and a cinema complex which need the large open spaces. The 192m-high building has 35 floors above ground and 4 below ground. The structure is a steel frame using CFT columns to feature the high-performance oil dampers and the buckling restrained braces for vibration control. First, an outline of the structural design of this building is presented. Second, we introduce the transfer frame adopted to realize the large open spaces in the lower part, and the long column supporting the corner part of the high-rise building to avoid making a shade on the adjacent Hibiya Park, which are the feature of this building. Finally, we present an outline of the latest highly efficient semi-active oil dampers adopted in this building, and the vibration responses of this tower.

• Advances in Computational Design
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• v.4 no.2
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• pp.179-196
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• 2019

Temporary scaffold systems in the construction site play an important role for ensuring the safety of the workers and for constructing the stable structures. To assemble the scaffold, the pipe scaffolding system, the wedge binding scaffolding system and the particular materials have been utilized. To design the material arrangement of a scaffold, firstly the configuration was determined considering the construction geometry. Then, the strength of the scaffold was confirmed and the quantity of the material was accounted. In this paper, the design method of the temporary scaffold was proposed for intending the semi-automatic procedure. In the proposed design method, the geometric design and the safety requirement were specified by the safety standard and the design flow was followed by the designer's knowledge. The size and the quantities of the materials were calculated by referring to the relation between the scaffold and the constructing structure. In the calculating procedure, three dimensional positions of each scaffold materials were calculated and recorded simultaneously. Then, three dimensional scaffold structural was drawn semi-automatically on the CAD software by using the obtained material sizes, positions and directions. The proposed design method provides us the precise quantities of scaffold materials and enables us to reduce the design effort and the cost estimation processes. In addition, the obtained results can be applied to BIM software after converting to IFC format.

• Korean Journal of Pharmacognosy
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• v.51 no.4
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• pp.317-324
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• 2020

Mast cells play a key role in IgE-mediated allergic response. We investigated whether Swertia pseudochinensis Hara extract (SPE) inhibits IgE-mediated allergic response in mast cells and an allergic animal model. Additionally, we explored SPE's mechanism of action in mast cells. Our results showed that SPE inhibited both antigen-stimulated degranulation and the production of TNF-α and IL-4 in bone marrow-derived mast cells (BMMCs) and rat basophilic leukemia (RBL)-2H3 cells. SPE also suppressed allergic response in IgE-mediated passive cutaneous anaphylaxis (PCA) in mice. As for the mechanism of action of SPE in mast cells, it inhibited the activation of Syk kinase, a critical signaling protein in the FcεRI-mediated signaling pathway, and also the activation of LAT, a downstream adaptor protein of Syk. We further observed the reduced activation of mitogen-activated protein (MAP) kinases (P38, ERK1/2, and JNK) and Akt in mast cells. Our results described for the first time that SPE has an anti-allergic effect by suppressing mast cells through the inhibition of Syk kinase. Therefore, SPE may be useful for the treatment of type I allergic diseases.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.6
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• pp.533-540
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• 2023

Sweroside is a natural monoterpene derived from Swertia pseudochinensis Hara. Recently, studies have shown that sweroside exhibits a variety of biological activities, such as anti-inflammatory, antioxidant, and hypoglycemic effects. However, its role and mechanisms in high glucose (HG)-induced renal injury remain unclear. Herein, we established a renal injury model in vitro by inducing human renal tubular epithelial cell (HK-2 cells) injury by HG. Then, the effects of sweroside on HK-2 cell activity, inflammation, reactive oxygen species (ROS) production, and epithelial mesenchymal transition (EMT) were observed. As a result, sweroside treatment ameliorated the viability, inhibited the secretion of inflammatory cytokines (TNF-α, IL-1β, and VCAM-1), reduced the generation of ROS, and inhibited EMT in HK-2 cells. Moreover, the protein expression of SIRT1 was increased and the acetylation of p65 NF-kB was decreased in HK-2 cells with sweroside treatment. More importantly, EX527, an inhibitor of SIRT1, that inactivated SIRT1, abolished the improvement effects of sweroside on HK-2 cells. Our findings suggested that sweroside may mitigate HG-caused injury in HK-2 cells by promoting SIRT1-mediated deacetylation of p65 NF-kB.

• Clinical Endoscopy
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• v.57 no.1
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• pp.122-127
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• 2024

Benign biliary stricture (BBS) is a complication of chronic pancreatitis (CP). Despite endoscopic biliary stenting, some patients do not respond to treatment, and they experience recurrent cholangitis. We report two cases of CP with refractory BBS treated using endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) fistula creation. A 50-year-old woman and a 60-year-old man both presented with obstructive jaundice secondary to BBS due to alcoholic CP. They underwent repeated placement of a fully covered self-expandable metal stent for biliary strictures. However, the strictures persisted, causing repeated episodes of cholangitis. Therefore, an EUS-CDS was performed. The stents were eventually removed and the patients became stent-free. These fistulas have remained patent without cholangitis for more than 2.5 years. Fistula creation using EUS-CDS is an effective treatment option for BBS.

• Korean Journal of Child Studies
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• v.38 no.1
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• pp.185-203
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• 2017

Objective: The present study examined the perspectives of grandparents raising their grandchildren in an attempt to better understand grandparents' child-rearing experience while providing kinship foster care to their primary-grade grandchildren. Methods: Data were collected through individual in-depth interviews with eight grandparents who have raised one or two primary-grade (ages 8-10) grandchildren using a qualitative approach. Results: First, the participants viewed the reason for their kinship foster care as a failure for caring for their own children and accepted the present grandparent-care provision as their responsibility. Second, the participants communicated constant struggles with their own health and grandchild-care as well as positive/negative emotions associated with the care provision. Third, most of the participants did not fully understand the developmental needs of their primary-grade grandchildren. Fourth, the participants articulated concerns for their primary-grade grandchildren's learning, peer interactions, school adjustment, and extra-curricular activities. Lastly, the participants all agreed on hoping to raise grandchildren with good personality traits as members of a society and to have them fill the gap from the loss of their parents. Conclusion: Although most participants accepted the current circumstances as their obligation, they still noted difficulties in child-care provision. Given the developmental needs of grandchildren and the resource needs of grandparents, proper and continuous intervention approaches should be developed/provided.

• Journal of Korean Dental Science
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• v.6 no.1
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• pp.13-21
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• 2013

Purpose: To report the successful results of using chin bone graft and autogenous tooth bone graft material (AutoBT) in alveolar cleft patients. Materials and Methods: Five patients with alveolar cleft defects underwent alveolar bone grafting. Three patients were treated using chin bone graft, and the other two patients underwent AutoBT graft. After implant site development using chin bone graft in the fi rst three cases, endosseous implant restorations were placed. In case #4 and 5, AutoBT graft material was placed to guide the normal eruption of partially impacted maxillary right canine and to the upper docking site after distraction osteogenesis. Result: Successful implant restorations with closure of the oronasal fistula were achieved in alveolar cleft defect reconstruction using either chin bone graft (Case #1, 2, 3) or AutoBT graft material (Case #4, 5). Case #4 showed enlarged follicle of the right maxillary canine, indicating a normal eruption guide pattern. Conclusion: Both chin bone graft and AutoBT graft showed favorable outcomes in reconstructing alveolar cleft defects. Autogenous tooth bone graft opens up the possibility of avoiding harvesting autogenous bone graft with complications and morbidities.

• Korean Journal of Medicinal Crop Science
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• v.15 no.4
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• pp.241-245
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• 2007

Effects of various concentrations of elicitors for enhancement in valepotriates and valerenic acids production in adventitious root culture of Valeriana fauriei were investigated. Although the growth of adventitious roots was suppresed by addition of biotic or abiotic elicitors, the production of valepotriates and valerenic acids was enhanced. Addition of $100\;{\mu}M$ methyl jasmonate or 1 $g/{\ell}$ yeast extract to the root culture of V. fauriei resulted in the optimal production of valepotriates ($12.56\;{\pm}\;0.78\;mg/{\ell}$) and valerenic acids ($10.63\;{\pm}\;1.1\;mg/{\ell}$), respectively.

• Korean Journal of Child Studies
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• v.36 no.3
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• pp.35-57
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• 2015

The present study employed a pretest-posttest quasi-experimental design model in order to evaluate the effectiveness of the Respected Parents & Respected Children (RPRC) parent education program for mothers of early school-age children. Ninety mothers were randomly assigned to an intervention (n=45) group or a control group (n=45). Mothers in the intervention group participated in 8 weekly sessions of the parent education program. After the termination of the program, the differences between pretest and posttest were analyzed in terms of both maternal parenting characteristics (i.e., parenting behavior, parenting efficacy, parenting stress, and co-parenting) and children's social competence. The results indicated that only in the intervention group, self-reported positive parenting characteristics were significantly improved and negative parenting characteristics were significantly decreased. There were no significant effects of the program on children's social competence as rated by the mothers. These findings suggest that the RPRC parent education program is effective in changing parenting characteristics known as crucial predictors of child outcomes.