• Archives of Pharmacal Research
• /
• v.28 no.12
• /
• pp.1392-1399
• /
• 2005

This study evaluated the effect of $\alpha$-tocopherol ($\alpha$-TC), ischemic preconditioning (IPC) or a combination on the extent of mitochondrial injury caused by hepatic ischemia/reperfusion (I/R). Rats were pretreated with $\alpha$-TC (20 mg/kg per day, i.p.) for 3 days before sustained ischemia. A rat liver was preconditioned with 10 min of ischemia and 10 min of reperfusion, and was then subjected to 90 min of ischemia followed by 5 h or 24 h of reperfusion. I/R increased the aminotransferase activity and mitochondrial lipid peroxidation, whereas it decreased the mitochondrial glutamate dehydrogenase activity. $\alpha$-TC and IPC individually attenuated these changes. $\alpha$-TC combined with IPC ($\alpha$-TC+IPC) did not further attenuate the changes. The mitochondrial glutathione content decreased after 5 h reperfusion. This decrease was attenuated by $\alpha$-TC, IPC, and $\alpha$-TC+IPC. The significant production of peroxides observed after 10 min reperfusion subsequent to sustained ischemia was attenuated by $\alpha$-TC, IPC, and $\alpha$-TC+IPC. The mitochondria isolated after I/R were rapidly swollen. However, this swelling rate was reduced by $\alpha$­TC, IPC, and $\alpha$-TC+IPC. These results suggest that either $\alpha$-TC or IPC reduces the level of mitochondrial damage associated with oxidative stress caused by hepatic I/R, but $\alpha$- TC combined with IPC offers no significant additional protection.

• Advances in concrete construction
• /
• v.3 no.2
• /
• pp.113-126
• /
• 2015

Holed-Incrementally Prestressed Concrete (H-IPC) girders are designed using the following new design concepts. At first, web openings reduce the self-weight of the girder, and also diffuse prestressing tendon anchorages. The reduced end anchoring forces decrease the web thickness of the end sections. Additionally, precast technology help to improve the quality of concrete and to reduce the construction period at the site. For experimentally verification, two 50 m full-scale H-IPC girders are manufactured with different concrete strength of 55 MPa and 80 MPa. The safety, stiffness, ductility, serviceability and crack development of H-IPC girder are measured and compared with each other for different strengths. Both girders show enough strength to carry live load and good stiffness to satisfy the design criteria. The experimental result shows the advantages of using high strength concrete and adopting precast girder. The test data can be used as a criterion for safety control and maintenance of the H-IPC girder.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.24 no.7
• /
• pp.949-955
• /
• 2020

In this Study, Social Network Analysis of IoT related patents in South Korea, China, and Japan was conducted from the viewpoint of patent informatics. To this end, 2,526 patents filed by PCT until December 2019 were investigated up to the subclass level of the IPC code. As a result, in the case of South Korea, representative IPC codes are in the order of G06Q, H04L, G06F, H04W, and the highest frequency of interconnection is H04L→H04W, H04W→H04L, H04W→H04B. In China, the representative IPC codes are in the order of H04L, H04W, G05B, G06Q. South Korea has strong technological convergence centered on the G06Q, while China has strong convergence centered around H04L and H04W. Moreover, in China, H04L and H04W have more diverse combinations than in South Korea in Section A, B, G, and H. In the future, it is necessary to study the diversity of technology convergence of H04L and H04W in China.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.25 no.11
• /
• pp.1642-1648
• /
• 2021

We analyzes representative technologies of IoT patents and reflects these results in the curriculum of IoT. In order to identify the representative technologies, the IPC codes of the patents were analyzed. Among the main category IPC codes, the most used IPC codes were H04L in Single IPC Patent with 974 cases(32.0%) and G06Q in Multiple IPC Patent with 710 cases(29.2%). As a result of classifying the IPC code into the WIPO technology classification system, the most emphasized technologies are Digital Communication, accounting for about 60.5% in the Single IPC Patent and IT Methods for Management(710 cases, 29.2%) in Multiple IPC Patent. The main points to be considered when organizing the curriculum of IoT are: ∇Emphasis on Digital Communication, ∇Expansion of Education related to IT Methods for Management(Including entrepreneurship and patent application), and ∇Consideration of subjects related to the Convergence of IoT. This research can contribute to the curriculum design of new industrial technologies such as AI and Fintech.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
• /
• v.15 no.5
• /
• pp.308-314
• /
• 2022

This study deals with the technology Convergence Analysis by IPC Code-Based Social Network Analysis of Healthcare Patents filed in Korea. The relationship between core technologies is visualized using Social Network Analysis. At the subclass level of healthcare patents, 1,155 cases (49.4%) of patents with complex IPC codes were investigated, and as a result of Social Network Analysis on them, the IPC codes with the highest Degree Centrality were A61B, G16H, and G06Q, in that order. The IPC codes with the highest Betweenness Centrality are in the order of A61B, G16H, and G06Q. In addition, it was confirmed that healthcare patents consist of two large technology clusters. Cluster-1 corresponds to related business models centered on A61B, G16H and G06Q, and Cluster-2 is consisting of H04L, H04W and H04B. The technology convergence core pairs of the healthcare patent is [G16H-A61B] and [G16H-G06Q] in Cluster-1, and [H04L-H04W] in Cluster-2. The results of this study can contribute to the development of core technologies for healthcare patents.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
• /
• v.9 no.3
• /
• pp.266-272
• /
• 2016

In this study, we analysed the technology convergence of Internet of Things(IoT) by International Patent Classification(IPC) code analysis. 163 patent applications in Korea are the subjects of this study. We confirmed that the most representative IPC code combinations between Main and Sub categories are G06Q 50/24-G06Q 50/22(6 cases), H04L 29/02-H04L 12/28(4 cases), G06F 15/16-G06F 3/048(3 cases), G06F 15/16-G06F 9/44(3 cases), and G06Q 50/22-G06Q 50/24(3 cases). The field of Health Care business have been prepared 9 patent applications by technology convergence between 'Health Care(G06Q 50/22)' and 'Patient Record Management(G06Q 50/24)'. Finally we also concluded that the core IPC code are G06F 15/16, G06Q 50/22, G06Q 50/24, and H04L 12/28 by the technology convergence interconnections analysis of IoT patent applications.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.10 no.2
• /
• pp.294-302
• /
• 2009

In this paper, the trend of technology and the business strategy on 'Hearing Aids' are investigated for the industry promotion of medical devices based on IT engineering from the 316 patents of 'Hearing Aids' registered in Korean Intellectual Property Office(KIPO). The classification of technology on 'Hearing Aids' is performed according to the IPC(International Patent Classification) code to and the core technology of 'Hearing Aids' As the results of classification of IPC code, the number of patents with IPC code 'H04R', 'H04B', 'H01M', and 'A61F' are 160, 46, 40, and 19 respectively. We found that the Digital technology and the Medical Transplants technology are come to the front of 'Hearing Aids' and the foreign 'Hearing Aids' companies are filed an application with the Korean Intellectual Property Office(KIPO) before their business.

• The Journal of Society for e-Business Studies
• /
• v.22 no.3
• /
• pp.1-28
• /
• 2017

Today, according to the increased importance of industry-university cooperation in the knowledge-based economy, support and the number of researches involved in industry-university cooperation has also steadily increased. But it is true that profits from the outcome of patents resulting from such cooperation, such as technology transfer and royalty fees, are lower than they are supposed to be, because of excessive patents applications, although some of them have little commercial potential. Therefore, this research aims to suggest a way to analyze and recognize patents, which enable efficient industry-university cooperation and technology transfer. For the analysis, data on 1,061 patents was collected from 4 different universities. With the data, a quality-strategy matrix was arranged targeting the industry-university cooperation foundations', US patents owned by universities, text mining, and social network analysis were carried out, particularly focusing on the patents in the advanced quality technology section of the matrix. Then core key words and IPC codes were obtained and key patents were analyzed by universities. As a result of the analysis, it was found that 4 key patents, 2 key IPC codes were drawn for University H, 4 key patents, 2 key IPC codes for University K, 6 key patents, 1 key IPC code for University Y, 14 key patents, and 2 key IPC codes for University S. This research is expected to have a great significance in contributing to the invigoration of industry-university cooperation based on the analysis result on patents and IPC codes, which enable efficient industry-university cooperation and technology transfer.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.5
• /
• pp.723-737
• /
• 2017

In order to decide the national technical standards policy for national policy/market economy activities, the people in charge commonly make policy decisions based on the current technology level/concentration/utilization by means of major common technology field analysis using patent data. One possible source of such patent data is the domestic mobile carriers through the Korea Intellectual Property Rights Information System (KIPRIS) of the Korean Intellectual Property Office (KIPO). Using this system, we collected 20,294 patents and 152 International Patent Classification (IPC) types and confirmed KTs (9,738 cases / 47.98%), which perform relatively high technology retention activities compared to other mobile carriers through the KIPRIS of KIPO. Based on these data, we performed three analyses (SNA, PCA, ARIMA) and extracted 30 IPC types from the SNA and 4 IPC types from the PCA. Based on the above analysis results, we confirmed that 4 IPC (H04W, H04B, G06Q, H04L) types are the major common technology field of the domestic mobile carriers. Finally, the number of 4 IPC (H04W, H04B, G06Q, H04L) forecast averages of the ARIMA forecast result is lower than the number of existing time series patent data averages.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.21 no.7
• /
• pp.625-637
• /
• 2020

In order to decide the naval ship weapon system acquisition for national policy/market economy activities, the decision makers can determine policy based on current technology level/concentration/utilization. For this, the decision makers apply the major common technology field analysis using patents data. As a method for collecting patent data, we can collect patent data of domestic mobile carriers through the Korea Intellectual Property Rights Information System of Korean Intellectual Property Office. As a result, we collected 14,964 patents/352 International Patent Classification(IPC) types. Based on these data, we performed three analysis processes (SNA, PCA, ARIMA, Text Mining) and got each result from extracting 58 IPC types of SNA and 7 IPC types of PCA. Based on the analysis results, we have confirmed that 7 IPC(B63B, H01M, F03D, B01D, H02K, B23K, H01H) types are the Major Common Technology Distribution of domestic Defense Companies.