• CELLMED
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• v.12 no.1
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• pp.5.1-5.8
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• 2022

Ābzan(sitz bath or hydration therapy) is one of the important and widely practised methods of regimenal therapy used for local evacuation or diversion of morbid humours described for various diseases in Unani system of medicine. Itis a type of bath in which hips and buttocks are immersed in water, either plain or medicated for therapeutic effects. Thus, it serves as an important and effective external mode of treatment. It has been successfully practised by Greeko-Arab physicians in the management of almost all types of gynaecological disorders like genital prolapse, leucorrhoea, pruritus vulvae, menstrual disorders, infertility, pelvic inflammatory diseases etc, but its efficacy has been proved in very few gynaecological diseases only. Hence, there is a need for systemic review to investigate the effectiveness of sitz bath in gynaecological disorders to generate scientific based evidence for the clinician as well as for common public. Based on the available literature, this review article suggests that the sitz bath has a scientific evidence-based effect in treating gynaecological diseases.

• The Korea Journal of Herbology
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• v.30 no.4
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• pp.11-20
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• 2015

Objectives : Ongyeong-tang (OGT) is a traditional herbal formula used to cure gynaecological disorders. OGT consists of 12 herbal medicines containing various bioactive components. Therefore, the development of suitable analytical method for the marker compounds is necessary for the quality control of OGT. Methods : Determination of the 18 marker compounds in OGT preparations was quantitatively performed by high-performance liquid chromatography-photodiode array detection analysis. The marker compounds were separated on a reversed-phase C ₁₈ column and the analytical method was successfully validated, which was applied to compare OGT extracts from laboratory preparation and commercial OGT granules. Results : Limit of detection and limit of quantification values were in the ranges of $0.001-0.016{\mu}g/mL$ and $0.003-0.047{\mu}g/mL$, respectively. Precision was 0.03-3.71 % within a day and 0.03-3.81 % over four consecutive days. Recovery of marker compounds ranged from 90.63-108.26 %, with relative standard deviation (RSD) values < 4.0 %. Reproducibility was < 2.5 % of the RSD value. The 18 marker compounds were stable within 16 h at $10^{\circ}C$, with the RSD value < 3.5 %. Quantitative analysis results showed that the quantities of the 18 marker compounds varied among OGT samples. Pearson coefficient evaluation and principal component analysis demonstrated that an OGT water extract produced by a laboratory method clearly differed from commercial OGT granules. Conclusions : The developed analytical method was simple, precise, and reliable. Therefore, it can be used for the quality assessment of OGT preparations.