• Journal of Sensor Science and Technology
• /
• v.16 no.3
• /
• pp.234-239
• /
• 2007

Crystallographically {h00}-oriented $0.94(Bi_{0.5}Na_{0.5})TiO_{3}-0.06BaTiO_{3}$ (0.94BNT-0.06BT) ceramics was prepared by the Reactive Templated Grain Growth (RTGG) method using the $Bi_{4}Ti_{3}O_{12}$ template. The sheets prepared by tape-casting of slurries containing the templates and starting materials are cut, laminated, and pressed. Then burn-out and sintering was conducted. Also, to compare with the 0.94BNT-0.06BT ceramics prepared by the RTGG method another 0.94BNT-0.06BT ceramics was prepared by the solid-state method. In the optimum of this experiments range, the degree of orientation of the 0.94BNT-0.06BT ceramics prepared by the RTGG method was texture fraction${\approx}92%$ and the piezoelectric constant($d_{33}$) and coupling factor($k_{p}$) was obtained to $d_{33}{\approx}205{\;}pC/N$, $k_{p}{\approx}0.33%$, respectively.

• Journal of Environmental Science International
• /
• v.4 no.5
• /
• pp.83-83
• /
• 1995

The increase of population and industrial activities had brought into eutrophication in the Nakdong river. A remarkable acceleration of eutrophication brought about serious problems for water supply. Therefore, for the purpose of conservation of water quality in the Nakdong river it is necessary to control nutrients. MBOD method was use to evaluate algal growth limiting factor and algal growth potential in the Nakdong river from June to August 1994. The modified biochemical oxygen demand(MBOD) depends on the amount of available inorganic nutrient and organic substrate during 5 day incubation in the dark at 20$^{circ}C$. The MBOD assay depends on inorganic nutrients such as P and N as well as reduced carbon and called the MBOD, the MBOD-P, and the MBOD-N, respectively. The results of bioassay by MBOD(Modified BOD) method showed that the MBOD, MBOD-P and MBOD-N value were found to be in the ranges of 3.8∼96.0 mg$O_2$/l, 5.6∼94.0 mg$O_2$/l and 42.0∼220 mg$O_2$/l, respectively. And the the bioassay value was found to be the highest in Koryong area and the lowest in Waekwan area throughout the Nakdong river. The variations of MBOD-P and MBOD-N value showed similar tendencies to the variations of phosphorus and nitrogen value, respectively. By MBOD method, the relationships of MBOD, MBOD-P and MBOD-N value were MBOD ≒ MBOD-P 《 MBOD-N. The MBOD value was nearly equal to the MBOD-P value, and the MBOD-N value was 3 to 20 times more than the MBOD-P value, approximately. Therefore, in the Nakdong river, phosphorus was the limiting factor for algal growth during summer season. The algal growth potential as the concentration of chlorophyll-a in the summer was maximum 5 times more than standing crop as it.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2000.10a
• /
• pp.124-127
• /
• 2000

The finite element analyses of the wrinkling initiation and growth in the sheet metal forming process provide the detailed information about the wrinkling behavior of sheet metal. The direct analyses of the wrinkling initiation and growth, however, bring about a little difficulty in complex industrial problems because it needs large memory size and long computation time. For the description of wrinkling growth, the mesh elements should be sufficiently small and the size of finite element matrix becomes large. In the static implicit finite element method therefore, the direct analysis of wrinkling growth in a complex sheet metal forming process is rather difficult. From the industrial viewpoint of tooling design, the readily available information of possibility and location of wrinkling is sometimes more preferable to the detailed time-consuming information. In the present study, therefore, the wrinkling factor that shows locations and relative possibility of wrinkling initiation is proposed as a convenient tool of relative wrinkling estimation based on the energy criterion. The location and relative possibility of wrinkling initiation are predicted by calculating the wrinkling factor in various sheet metal forming processes such as cylindrical cup deep drawing, spherical cup deep drawing, and elliptical cup deep drawing. The wrinkling factor is also implemented in the analysis of the door inner stamping process to predict wrinkling.

• Journal of the Korean Society of Safety
• /
• v.16 no.1
• /
• pp.31-36
• /
• 2001

Surface crack growth characteristics and influence of the stress amplitude in rotary bending fatigue test were evaluated for annealed S35C steel, and than fractal dimensions of fatigue crack paths estimated using the box counting method. The following results that will be helpful to understand the fatigue crack growth mechanism were obtained. (1) Crack growth rate ds/dN and db/dN (s : half crack length at the surface crack, b : crack depth) depended on stress amplitude (${\Delta}{\sigma}/2$), stress intensity factor range (${\Delta}K_A, {\Delta}K_C$) and crack length. (2) At the effect area of 0.3 mm hole notch (s＜0.5 mm) crack growth rate did not depend on these factors. (3) The fractal dimensions (D) increased with stress amplitude (${\Delta}{\sigma}/2$) but decreased with cyclic number.

• Journal of Ocean Engineering and Technology
• /
• v.9 no.1
• /
• pp.83-91
• /
• 1995

Surface defects in structural members are apt to be origins of fatigue cracks growth, which may cause serious failure of whole structures. Most structure has a part where stress concentrates such as welded joints, corner parts, etc. And then, analysis on crack growth and penetration from these defects, therefore, is one of the most important subjects for the reliability of LBB design. The present paper has performed an experimental and analysis on the fatigue crack propagation by variety in crack length of surface cracked plate with stress concentration part. The crack growth behavior can be explained quantitatively by using Newman-Raju equation and the stress partitioning method proposed by ASME B&P Code Sec. XI. The stress concentration factor $K_t$ has affected on the crack growth. The crack growth after penetration depends upon the initial front side crack length.

• Proceedings of the KSME Conference
• /
• 2001.06a
• /
• pp.187-192
• /
• 2001

Cracks in mechanical joints is generally under mixed-mode and there is the critical inclined angle at which mode I stress intensity factor becomes maximum. In order to evaluate the fatigue life of cracks in mechanical joints, horizontal crack normal to the applied load and located on minimum cross section is major concern but critical inclined crack must also be considered. In this paper mixed-mode fatigue crack growth test is performed for horizontal crack and critical inclined crack in mechanical joints. Fatigue crack growth path is predicted by maximum tangential stress criterion using mode I and mode II stress intensity factors obtained from weight function method, and fatigue crack growth rates of horizontal and inclined crack are compared.

• Journal of the Korean Society for Precision Engineering
• /
• v.17 no.4
• /
• pp.197-202
• /
• 2000

A simple numerical procedure is presented to determine the stress intensity factors for crack in a stiffened panel subjected to a uniaxial uniform stress normal to the crack. Two types of stiffened panels are analyzed by the finite element method for various values of crack lengths, stiffness ratios, and stiffener spacings. From the finite element solution, the stress intensity factors were determined by using hybrid extrapolation method. Results are presented in graphical forms for upper mentioned parameters.

• Journal of Ocean Engineering and Technology
• /
• v.8 no.2
• /
• pp.115-123
• /
• 1994

Under variable amplitude loading conditions, retardation or accelerated condition of fatigue crack growth occurs with every cycle, Because fatigue crack growth behavior varied depend on load time history. The modeling of stress amplitude with storm loading acted to ships and offshore structures applied this paper. The crack closure behavior examine by recording the variation in load-strain relationship. By taking process mentioned above, fatigue crack growth rate, crack length, stress intensity factor, and crack closure stress intensity factor were obtained from the stress cycles of each type of storm ; A(6m), B(7m), C(8m), D(9m), E(11m) and F(15m) which was wave height. It showed that the good agreement with between the experiment results and simulation of storm loads. So this estimated method of crack propagtion rate gives a good criterion for the safe design of vessels and marine structure.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.29 no.2
• /
• pp.113-122
• /
• 2007

Purpose: Platelet-rich plasma (PRP) is known to accelerate and/or enhance hard and soft tissue healing and regeneration. As such, PRP has been used in various clinical fields of surgery. Recently there have been several attempts to use PRP in the field of tissue engineering. However, some controversies still exist on exact mechanism and benefits of PRP. Therefore various animal experiments are necessary to reveal the effect of the PRP. However, even if animal experiment is performed, the efficacy of the experiment could not be validated due to absence of an animal PRP model. The purpose of this study is to establish rat PRP model by comparing several PRP fabricating methods, and to assay growth factor concentration in the PRP. Materials and methods: Rat blood samples were collected from nine SD rat (body weight: 600-800g). PRP was prepared using three different PRP fabricating methods according to previously reported literatures. (Method 1: 800 rpm, 15 minute, single centrifuge; Method 2: 1000 rpm, 10 minute, double centrifuge; Method 3: 3000 rpm, 4min and 2500 rpm, 8 min, double centrifuge). Platelet counts were evaluated in an automated machine before and after PRP fabrications. In terms of growth factor assay, prepared PRP were activated with 100 unit thrombin and 10% calcium chloride. Growth factor (PDGF-BB, VEGF) concentrations on incubation time were determined by sandwich-ELISA technique. Results: An average of 3ml (via infraorbital venous plexus) to 15ml (via celiac axis) the rat blood could be collected. By using Method 3 (3000 rpm, 4 min and 2500 rpm, 8 min, double centrifugation), around 1.5ml of PRP could be prepared. This method allowed us to concentrate platelet 3.77-fold on average. PDGF-BB concentration (mean, 1942.10 pg/ml after 1 hour incubation) and VEGF concentration (mean, 952.71 pg/ml after 1 hour incubation) in activated PRP were higher than those in untreated blood. Also PDGF-BB showed constant concentration during 4-hour incubation, while VEGF concentration was decreased after 1 hour. Conclusion: Total 11,000 g minute separation and condensation double centrifuge method can produce efficient platelet-rich plasma. Platelet-rich plasma activated with thrombin has showed higher concentrations of growth factors such as PDGF-BB and VEGF, compared to the control group. Platelet-rich plasma model in a rat model was confirmed in this study.

• Archives of Pharmacal Research
• /
• v.24 no.4
• /
• pp.355-359
• /
• 2001

A novel HPLC method with electrochemical detection has been developed for the determination of recombinant human epidermal growth factor (rhEGF) in pharmaceutical products. rhEGF was separated from other components in formulation on a reversed-phase C18 column with 24% acetonitrile in 0.1 M phosphate buffer (pH 4.75). The optimum electrochemical oxidation of EGF was obtained at 0.85 V vs. Ag/AgCl in a glassy carbon working electrode due to electroactive tyrosine, tryptophan, methionine, and arginine residues. The quantitation range was from 1.0 to 200 ng of rhEGF with the linear correlation coefficient greater than 0.999. The method was successfully applied for the quantitation of rhEGF in a pharmaceutical preparation.