• 제목/요약/키워드: Growth interruption

검색결과 63건 처리시간 0.023초

가로수의 유형 및 성장을 고려한 보행로 조명환경 개선에 관한 시뮬레이션 연구 (A Simulation Study on the Improvement of Lighting Condition on Sidewalks Considering the Type and Growth of Roadside Trees)

  • 이종성;이석준
    • 대한안전경영과학회지
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    • 제15권3호
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    • pp.93-103
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    • 2013
  • In recently, a growing concern for the health of urban residents increased interests in a variety of outdoor activities simply be done in terms of cost and time. They are specially interested in low-impact and safe exercises around residential or working area. Walking is the one of easily doing exercise in daytime or nighttime near residential area. The sidewalks of boulevard near the residential area is the best place for exercise because of easy access and the green space with roadside trees. However, if the nighttime is not guaranteed the proper lighting condition, the possibility of exposure to crime and the threat to pedestrian safety can be increased. Because roadside trees are one of the potential obstacle for lighting condition, supplementary lightings are important to mitigate interruption for safety. To meet such a need, the purpose of this study is to propose a simulation approach which improves lighting condition on sidewalks of boulevard with variety of roadside trees. To do so, the simulation approach is applied for analyzing the interrupted condition by classified five standard types of roadside trees considering the growth of them and finding optimal layout of supplementary luminaires by lighting types. The results of this approach shows that it is useful for assessing the safety of pedestrian in nighttime.

P42 Ebp1 functions as a tumor suppressor in non-small cell lung cancer

  • Ko, Hyo Rim;Nguyen, Truong L.X.;Kim, Chung Kwon;Park, Youngbin;Lee, Kyung-Hoon;Ahn, Jee-Yin
    • BMB Reports
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    • 제48권3호
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    • pp.159-165
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    • 2015
  • Although the short isoform of ErbB3-binding protein 1 (Ebp1), p42 has been considered to be a potent tumor suppressor in a number of human cancers, whether p42 suppresses tumorigenesis of lung cancer cells has never been clarified. In the current study we investigated the tumor suppressor role of p42 in non-small cell lung cancer cells. Our data suggest that the expression level of p42 is inversely correlated with the cancerous properties of NSCLC cells and that ectopic expression of p42 is sufficient to inhibit cell proliferation, anchorage-independent growth, and invasion as well as tumor growth in vivo. Interestingly, p42 suppresses Akt activation and overexpression of a constitutively active form of Akt restores the tumorigenic activity of A549 cells that is ablated by exogenous p42 expression. Thus, we propose that p42 Ebp1 functions as a potent tumor suppressor of NSCLC through interruption of Akt signaling.

부모의 양육방식이 초등학교 고학년의 학교생활 적응의 변화 궤적에 미치는 영향 (The Effects of Parenting Practice on the Trajectories of Change in the School Adjustment of Upper Elementary Students)

  • 이정민;강수정;이강이;이순형
    • 아동학회지
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    • 제36권4호
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    • pp.91-110
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    • 2015
  • In upper elementary period school adjustment and the effect of parenting face a new set of dynamics. We assumed that parental supervision, affection, incoherence, over-expectation, over-interruption and logical explanation would have an effect on individual trajectories in the development of school adjustment. Additionally, we hypothesized that this model would be different among boys and girls. In this study we analyzed three waves of data collected from 2,378 children nationwide in South Korea. This data was gathered from the Panel Study of Korean Youth and Adolescents conducted by the National Youth Policy Institute(NYPI). Growth-curve longitudinal analysis was conducted and the results indicate that levels of school adjustment had decreased through the $4^{th}$ to $6^{th}$ grade. Parents' supervision, affection and logical explanation significantly predict children's initial school adjustment as well as their rate of decrease in their levels of school adjustment. Parents' supervision had a positive effect on girls' school adjustment. Parents' over-expectation had negative effect on boys' school adjustment levels. Policy implications and future directions for research were also discussed.

단일식물의 개화유도를 조절하는 개화억제요소의 규명과 Phytochrome의 역할에 관한 연구 (Studies on Inhibition Factors and the Role of Phytochrome in the Floral Induction in Short-day Plants)

  • 맹주선
    • Journal of Plant Biology
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    • 제19권1호
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    • pp.14-18
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    • 1976
  • Inhibition of flowering in Lemna perpusilla 6746 by 30 mM sucrose was reversed by the addition of acetylcholine (>$10^{-4}M) supplemented with 10^{-4}M$ ascorbic acid to 1/10-strength Hunter's growth medium. The reversible effect of acetylcholine was found to be greater at early stages of flowering than in the later period. Promotive effects of both acetylcholine ($10^{-3}M) and eserine(10^{-5}M$) on flowering in the short-day plant under various photoperiodic conditions were studied. It was indicated that the application decreased length of the critical dark period for the floral induction, and it was also shown that the endogenous status of acetylcholine was involved in the floral response which had a correlation with phytochrome. Interruption of inductive dark periods by red irradiation (1min) immediately followed by far-red light (1 min) completely inhibited flowering, while the addition of acetylcholine and eserine to the medium under the same condition slightly promoted flowering, indicating possible involvement of phytochrome system in acetylcholine activity for photoperiodic sensitivity of floral response in Lemna perpusilla 6746.

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Ni/Ni-aluminide//Ti/Ti-aluminide 구조경사형 층상재료의 균열 전파 거동 (Crack propagation behavior of in-situ structural gradient Ni/Ni-aluminide//Ti/Ti-aluminide laminate materials)

  • 정동석;김진곤;조현
    • 한국결정성장학회지
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    • 제15권6호
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    • pp.269-275
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    • 2005
  • Ni/Ni-aluminide//Ti/Ti-aluminide 경사기능 층상 복합재료를 박막 hot press법을 이용하여 제작하였다. NiAl과 $TiAl_3$ 금속간화합물 층이 자전고온합성반응을 통해 비교적 두껍게 형성되었고, 얇고 연속적인 $Ni_3Al$과 TiAl 층이 고상 확산을 통해 형성되었다. 파괴저항은 하중 방향이 crack arrester인 경우가 금속 층이 균열의 성장을 방해하기 때문에 crack divider 방향인 경우보다 높다. $Ni_3Al$과 NiAl 금속간화합물 층은 각각 벽개파괴와 입계파괴 거동을 보였고, $TiAl_3$층의 파괴 형태는 입내벽개파괴이었다. Ni/Ni-aluminide 층에서 관찰되는 기공과 금속 층과 금속간화합물 층의 미결합 부위가 낮은 파괴저항의 원인으로 판단된다. Acoustic emission (AE) 원파형 해석을 통해 제작된 복합재료의 파괴특성을 고찰하였다.

편측 구순구개열 환자에서 ANS 골절단술을 이용한 코 비대칭의 교정 (ANS Repositioning for Correction of Asymmetric Nose in Unilateral Cleft Lip and Palate)

  • 정영수;김기호;이상휘;이충국
    • 대한구순구개열학회지
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    • 제8권2호
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    • pp.87-94
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    • 2005
  • Patients with unilateral cleft lip and palate (UCLP) generally demonstrate the asymmetries in the lip, nose and the naso-maxillary complex. And their skeletal asymmetries are known to be derived from the displacement of nasal septum, anterior nasal spine (ANS) and the pre-maxilla toward the non-affected side during the developmental and growth period. Due to the interruption of the important facial muscles, which are critical for the symmetric growth of premaxilla, functional matrix system fails to develop and results in the displacement of the ANS toward the non-affected side and nasal asymmetry. Therefore the rhinoplasty for CLP patients is required to have inter-skeletal and muscular rearrangement in the naso-maxillary complex in order to let them recover from esthetic and physiologic imbalances. And functional cheilorhinoplasty (FCR) has been a representative treatment of choice for this concept of treatment modality. The outcome and prognosis of primary or repair FCR have been known to be definitely affected by timing of the operation as well as adequate reconstruction of naso-labial muscles. However, sometimes FCR has an ineffective treatment results for patients after the facial growth period, and the limited rhinoplasty around the nose often fails to bring satisfying results. In order to circumvent this limitation, we performed ANS osteotomy for patients with unilateral CLP showing asymmetric nose, as an alternative way for corrective rhinoplasty. We could observe that the nose was rearranged along the facial mid-line by this osteotomy design and asymmetries were evidently improved postoperatively. Here we present this osteotomy method in CLP patients.

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비대칭 입력 전압 상태를 고려한 LIDVR의 새로운 제어방법 (New Control Scheme for LIDVR Considering Asymmetry Input Voltage Conditions)

  • 한철우;김태진;강대욱;현동석
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2002년도 전력전자학술대회 논문집
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    • pp.510-514
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    • 2002
  • Power Quality and reliability are becoming important issues for critical and sensitive loads. The recent growth in the use of impactive and nonlinear loads has caused many power quality problems such as voltage flicks, harmonics and unbalances, which may cause the modem automatic devices to fail, misoperate, or shut down. This paper deals with 7-Level H-Bridge Line-Interactive Dynamic Voltage Restorer (LIDVR) system. It has the power factor near to unity under normal source voltage, can compensate the harmonic current of the load and instant interruption, and has the fast response. Currently, most of the DVR design studies are based on the assumption of the balanced three-phase system. But, actually line fault occurred $1{\phi}\;{sag}\;or\;2{\phi}$ sag. Hence, proposed new control scheme compensate asymmetry input voltage. Finally, simulation results verify the proposed 7-Level H-Bridge LIDVR system.

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W-Ni-Fe 중합금의 미세조직 변화에 대한 μ-phase의 영향 (Effect of μ-Phase on Microstructural Change of W-Ni-Fe Heavy Alloys)

  • 김대건;김은표;김영도
    • 한국재료학회지
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    • 제12권1호
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    • pp.16-20
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    • 2002
  • In this study, the 95W heavy alloys of 3/7, 5/5 and 7/3 of Ni/Fe ratio were sintered at the temperature range between 1420 and $1480^{\circ}C$ for 1h and their microstructures were discussed for an effect of the ${\mu}$-phase $(Fe_7W_6)$ on the microstructure. The ${\mu}$-phase was observed in the only 95W-1.5Ni-3.5Fe alloy of 3/7 and it is thought to be formed and grown from the surface of the W particle. The W particle was surrounded with the ${\mu}$-phase and there were only the W particles and this phase without Ni-Fe-W matrix at the most part. The ${\mu}$-phase changed the interphase structure in the alloy and the grain growth of the W was suppressed because of interrupting the solution-reprecipitation of the W. The W content in the matrix was considered to be lowered due to the interruption of the solution-reprecipitation and the formation of the ${\mu}$-phase in the .

코골이와 수면무호흡증 환자의 임상적 특징과 치료계획 (Clinical characteristics and treatment plan for patients with snoring and obstructive sleep apnea)

  • 정재광;김기림;변진석;최재갑
    • 대한치과의사협회지
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    • 제53권4호
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    • pp.249-258
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    • 2015
  • Snoring and obstructive sleep apnea are the representative sleep disordered breathings, caused by the temporary and repetitive constriction or obstruction of upper airway during sleep. They present with excessively vibratory noise and repetitive cease of respiration. These disorders commonly result in sleep disturbance and the subsequent daytime sleepiness, chronic fatigue. Furthermore, they can cause the serious and extensive complications including increased risk of hypertension, cardiac arrhythmia, cardiovascular disease, cerebrovascular accident, neurocognitive disturbance, traffic and occupational accidents, type II diabetes, childhood growth interruption, awakening headache and finally, relatively increased mortality rate. Because appropriate therapeutic intervention is best way for patients to relieve their symptoms and prevent their possible complications, it is very important for dentists to recognize their own role and responsibility in diagnosis and treatment of these disorders. For this, the present article provides the understanding of the clinical features, possible complications, various treatment modalities, and suitable treatment strategies for snoring and obstructive sleep apnea.

Characterisation of Tensile Deformation through Infrared Imaging Technique

  • B. Venkataraman, Baldev Raj;Mukhophadyay, C.K.
    • 비파괴검사학회지
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    • 제22권6호
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    • pp.609-620
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    • 2002
  • It is well known that during tensile testing, a part of the mechanical work done on the specimen is transformed into heat energy. However, the ultimate temperature rise and the rate of temperature rise is related to the nature of the material, conditions of the test and also to the deformation behaviour of the material during loading. The recent advances in infrared sensors and image/data processing techniques enable observation and quantitative analysis of the heat energy dissipated during such tensile tests. In this study, infrared imaging technique has been used to characterise the tensile deformation in AISI type 316 nuclear grade stainless steel. Apart from identifying the different stages during tensile deformation, the technique provided an accurate full-field temperature image by which the point and time of strain localization could be identified. The technique makes it possible to visualise the region of deformation and failure and also predict the exact region of fracture in advance. The effect of thermal gradients on plastic flow in the case of interrupted straining revealed that the interruption of strain and restraining at a lower strain rate not only delays the growth of the temperature gradient, but the temperature rise per unit strain decreases. The technique is a potential NDE tool that can be used for on-line detection of thermal gradients developed during extrusion and metal forming process which can be used for ensuring uniform distribution of plastic strain.