• Title/Summary/Keyword: Growth disturbance

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Feasibility of Endoscopic Endonasal Approach for Recurrent Pituitary Adenomas after Microscopic Trans-Sphenoidal Approach

  • Hwang, Joo Min;Kim, Yong Hwy;Kim, Jin Wook;Kim, Dong Gyu;Jung, Hee-Won;Chung, Young Seob
    • Journal of Korean Neurosurgical Society
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    • v.54 no.4
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    • pp.317-322
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    • 2013
  • Objective : The surgical approach for recurrent pituitary adenoma after trans-sphenoidal approach (TSA) is challenging. We report the outcomes of the endoscopic TSA for recurrent pituitary adenoma after microscopic TSA. Methods : From February 2010 to February 2013, endoscopic TSA was performed for removal of 30 recurrent pituitary adenomas after microscopic TSA. Twenty-seven (90%) patients had a clinically non-functioning pituitary adenoma. Twenty-four (80%) patients suffered from a visual disturbance related to tumor growth. The clinical features and surgical outcomes were retrospectively analyzed for the ophthalmological, endocrinological, and oncological aspects. Results : The mean tumor volume was 11.7 $cm^3$, and gross total resection was achieved in 50% of patients. The volumetric analysis based on the postoperative MR showed that the mean extent of resection rates were 90%. Vision was improved in 19 (79%) of 24 patients with visual symptoms, and endocrinological cure was achieved in all of three functioning pituitary adenomas; however, the post-operative follow-up endocrinological examination revealed a new endocrinological deficit in one patient. Two patients required antibiotics management for post-operative meningitis. Conclusion : The endoscopic TSA can be an effective treatment option for recurrent pituitary adenoma after microscopic TSA with acceptable outcome.

Inducer Design to Avoid Cavitation Instabilities

  • Kang, Dong-Hyuk;Watanabe, Toshifumi;Yonezawa, Koichi;Horiguchi, Hironori;Kawata, Yutaka;Tsujimoto, Yoshinobu
    • International Journal of Fluid Machinery and Systems
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    • v.2 no.4
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    • pp.439-448
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    • 2009
  • Three inducers were designed to avoid cavitation instabilities. This was accomplished by avoiding the interaction of tip cavity with the leading edge of the next blade. The first one was designed with extremely larger leading edge sweep, the second and third ones were designed with smaller incidence angle by reducing the inlet blade angle or increasing the design flow rate, respectively. The inducer with larger design flow rate has larger outlet blade angle to obtain sufficient pressure rise. The inducer with larger sweep could suppress the cavitation instabilities in higher flow rates more than 95% of design flow coefficient, owing to weaker tip leakage vortex cavity with stronger disturbance by backflow vortices. The inducer with larger outlet blade angle could avoid the cavitation instabilities at higher flow rates, owing to the extension of the tip cavity along the suction surface of the blade. The inducer with smaller inlet blade angle could avoid the cavitation instabilities at higher flow rates, owing to the occurrence of the cavity first in the blade passage and its extension upstream. The cavity shape and suction performance were reasonably simulated by three dimensional CFD computations under the steady cavitating condition, except for the backflow vortex cavity. The difference in the growth of cavity for each inducer is explained from the difference of the pressure distribution on the suction side of the blades.

Ecological Responses of Plants to Climate Change: Research Trends and Its Applicability in Korea (기후변화에 대한 식물의 생태적 반응: 연구동향과 한국에서의 적용가능성)

  • Kang, Hyesoon
    • Korean Journal of Ecology and Environment
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    • v.46 no.3
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    • pp.319-331
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    • 2013
  • Recent climate change, which is mostly ascribed to anthropogenic activities, is believed to be a major factor leading to biodiversity decreases and ecosystem service deteriorations. I have reviewed recent studies on climate change effects for many ecological processes involved with plants, in order to improve our understanding of the nature of ecological complexity. Plants in general have better growth and productivity under high levels of $CO_2$, although the long term effects of such $CO_2$ fertilizers are still controversial. Over the last 30 years, the Earth has been greening, particularly at higher latitudes of the Northern Hemisphere, perhaps due to a relaxation of climatic constraints. Human appropriation of net primary productivity (NPP), which corresponds up to 1/3 of global NPP, is ultimately responsible for climate change and biodiversity decreases. Climate change causes phenological variations in plants, especially in regards to spring flowering and fall leaf coloring. Many plants migrate polewards and towards higher altitudes to seek more appropriate climates. On the other hand, tree mortality and population declines have recently been reported in many continents. Landscape disturbance not only hinders the plant migration, but also makes it difficult to predict the plants' potential habitats. Plant and animal population declines, as well as local extinctions, are largely due to the disruption of species interactions through temporal mismatching. Temperature and $CO_2$ increase rates in Korea are higher than global means. The degree of landscape disturbances is also relatively high. Furthermore, long-term data on individual species responses and species interactions are lacking or quite limited in Korea. This review emphasizes the complex nature of species responses to climate change at both global and local scales. In order to keep pace with the direction and speed of climate change, it is urgently necessary to observe and analyze the patterns of phenology, migration, and trophic interactions of plants and animals in Korea's landscape.

The Correction of a Secondary Bilateral Cleft Lip Nasal Deformity Using Refined Open Rhinoplasty with Reverse-U Incision, V-Y Plasty, and Selective Combination with Composite Grafting: Long-term Results

  • Cho, Byung-Chae;Choi, Kang-Young;Lee, Jung-Hun;Yang, Jung-Dug;Chung, Ho-Yun
    • Archives of Plastic Surgery
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    • v.39 no.3
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    • pp.190-197
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    • 2012
  • Background : This article presents long-term outcomes after correcting secondary bilateral cleft lip nasal deformities using a refined reverse-U incision and V-Y plasty or in combination with a composite graft in order to elongate the short columella. Methods : A total of forty-six patients underwent surgery between September 1996 and December 2008. The age of the patients ranged from 3 to 19 years of age. A bilateral reverse-U incision and V-Y plasty were used in 24 patients. A composite graft from the helical root was combined with a bilateral reverse-U incision in the 22 patients who possessed a severely shortened columella. The follow-up period ranged between 2 and 10 years. Results : A total of 32 patients out of 46 were evaluated postoperatively. The average columella length was significantly improved from an average of 3.7 mm preoperatively to 8.5 mm postoperatively. The average ratio of the columella height to the alar base width was 0.18 preoperatively and 0.29 postoperatively. The postoperative basal and lateral views revealed a better shape of the nostrils and columella. The elongated columella, combined with a composite graft, presented good maintenance of the corrected position with no growth disturbance. A composite graft showed color mismatching in several patients. Twenty-six patients demonstrated no alar-columella web deformity and satisfactory symmetry of the nostrils. Four patients experienced a drooping and overhanging of the corrected alar-columella web. Conclusions : A bilateral reverse-U incision with V-Y plasty or in combination with a composite graft was effective in correcting secondary bilateral cleft lip nasal deformity.

Estimation of Characteristic of the Soil Physical using the Pipe Type Soil Sampler (원관형 토양샘플러를 이용한 토양물리특성 추정)

  • Ryu, Ji Hyun;Jung, Myung Kwan;Park, Seung Ki
    • Journal of The Korean Society of Agricultural Engineers
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    • v.62 no.1
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    • pp.95-104
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    • 2020
  • The purpose of this study is to develop a pipe type soil sampler that can easily collect soil cross section servey and soil samples to conduct ecological environment surveys while minimizing ecological disturbance in the area subject to soil survey. Furthermore, this study develop the exponential type estimation specific weight formula (ESWF) that uses pipe type soil sampler to easily carry out soil cross section survey and soil sample while estimating the specific weight of the area using water content and soil sample length variation ratio (SLVRs) and to obtain apparent specific gravity, hardness, and max. porosity which are used as growth of corps and ecological environment index. The calibration results of ESWF showed a high degree of significance, with NSE for actual specific weight (γ0) and calibration estimation specific weight (γec) 0.95, R2 for 0.954, and RMSE for 0.051. The verification results of ESWF showed a high significance, with NSE for actual specific weight (γ0) and verification estimation specific weight (γev) 0.881, R2 for 0.978, and RMSE for 0.055.

FUNCTIONAL RECOVERY OF MANDIBULAR HIGH CONDYLAR FRACTURE PATIENT WITH IMMEDIATE PROVISIONAL IMPLANT: CASE REPORT (Immediate provisional implant를 이용한 하악골 high condylar fracture환자의 기능회복: 증례보고)

  • Jang, Bo-Young;Ahn, Mi-Ra;Ahn, Kyung-Mi;Lee, Won-Hyuk;Shon, Dong-Seok
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.31 no.1
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    • pp.82-88
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    • 2005
  • Treatment methods of mandibular condylar fracture were conservative and surgical method. Surgical method of mandibular high condylar fracture was very difficult because approach and internal fixation of small size fracture fragment were difficult. So there is a tendency to select conservative method over surgical method for guiding a stable occlusion and avoiding TMJ disorder and growth disturbance, minimizing pain and deviation during function. But, in case of mandibular high condylar fracture patient who has no biting teeth on posterior teeth area, guiding a stable occlusion and conservative functional treatment were very difficult. In this case, patient was 62years old male. He had fracture of mandibular symphysis, right mandibular body, left mandibular high condyle. We treated the patient for mandibular symphysis and right mandibular body fracture area with surgical method. But left mandibular high condylar fracture area was difficult to treat with surgical method. So we selected a conservative functional method on left mandibular high condylar fracture area. We intended recovery of vertical dimension and stable occlusion with implantation of immediate provisional implant on maxillar and mandibular posterior teeth area, and temporary crown. And then patient did mandibular functional movement and his mandibular function was recoverd.

A CASE REPORT OF NEUROCRISTOPATHY THAT SHOWS OBLIQUE FACIAL CLEFT, MAXILLARY DUPLICATION AND OTHER FACIAL MALFORMATIONS (사선안면열, 상악돌기 중복 등 복합 기형을 유발한 신경능병변 환자의 치험례)

  • Ryu, Dong-Mok;Lee, Sang-Chull;Kim, Yeo-Gab;Lee, Baek-Soo;Choi, You-Sung
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.21 no.4
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    • pp.407-413
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    • 1999
  • Maxillary duplication is a kind of proliferative neurocristopathy and considered to arise from bifurcation of neural crest elements soon after migration into mandibular arch. Sometimes this malformation is accompanied with oblique facial cleft. Usually this type of maxillofacial malformation requires multiple surgical intervention and the results are far from ideal. It became more troublesome if it had not been properly corrected on time, because secondary deformities could be developed from growth and development of abnormal tissues. This is a case of a 25-year-old-female patient who showed severe facial asymmetry thought to secondary deformity of maxillary duplication and masticatory disturbance due to multiple supernumerary teeth on posterior part right maxilla. We successully treated these deformities through four times of surgery of bone resection, orthodontic treatment, zygomatic and orbital reconstruction, orthognathic surgery and scar revision... ect. So we reported this rare case with review of literatures.

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Community Type and Stand Structure of the Korean Pine(Pinus koraiensis) Natural Forest in Seoraksan National Park (설악산 국립공원 잣나무 천연림의 군락유형 및 임분구조)

  • Song, Youn-Hee;Yun, Chung-Weon
    • Korean Journal of Environment and Ecology
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    • v.20 no.1
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    • pp.29-40
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    • 2006
  • This study was conducted to obtain the fundamental data for the ecological management in the Pinus koraiensis natural forest in Seoraksan National Park. The community types of the P. koraiensis forest were divided into Ainsliaea acerifolia group and Rhododendron schlippenbachii group. A. acerifolia group was subdivided into Acer tschonoskii var. rubripes subgroup and Calamagrostis arundinacea subgroup. The importance value of major species showed higher value in the order like Pinus koraienses, Abies nephrolepis, Acer barbinerve, Betula ermani, Acer pseudo-sieboldianum, Sorbus commixta and Quercus mongolica. The value of species diversify ranged from 0.44 to 0.86, and showed stronger competition in the interspecific association than in the intraspecific one. The number of individuals of P. koraiensis below 10 centimeters in the 15 study sites was 35, and it was considered that the population of P. koraiensis could be succeeded to the other species in the present situation because of lower frequency in the low layer though the canopy of tree layer was dominated with P. koraiensis. The radial growth patterns of P. koraiensis individuals were mainly fluctuated for the entire life time, which was considered to be caused by frequent disturbance.

Conservation of an Endangered Corylopsis coreana Uyeki in and ex situ and Development of Cooperative Model within Local Community - III. Populational Comparison Between Natural Groups and Deforestation Groups of Corylopsis coreana UYEKI (보호종인 히어리의 자생지내외 보전과 지역사회 협력 모델 개발 - III. 몇 개의 히어리 자연집단과 벌채집단 간 개체군 비교)

  • Lim Dong-Ok;Hwang In-Chon;Choung Heung-Lak
    • Korean Journal of Environment and Ecology
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    • v.20 no.2
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    • pp.227-234
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    • 2006
  • The comparison of Corylopsis coreana populations between natural groups and deforestation groups is carried in five regions such as Seungju, Woldeung, Hwangjeon in Suncheon, Myeongseok in Jinju and Mt. Baegun in Pocheon. The number of sprouting per both $100m^2$ and each individual stump were appeared more in deforestation than in natural groups. In contrast, the height and the diameter of individuals by the number of sprouting are higher and larger in the natural groups. The relationship between the floristic composition and vegetation in the two groups of C. coreana populations was not appeared. Corylopsis coreana are propagated sprouting as well as seedling in deforestation groups located an opening area. Because of the powerful environmental adaptability through growth of the sprouting and the seedling in deforestation groups, the population of C. coreana are not extinction of species oneself, and on the contrary are showed expansion of C. coreana population after temporary disturbance.

A Prognosis Evaluation after Iliac Bone Graft in Cleft Alveolus Patients (치조열 환자의 장골이식술 후 예후 평가)

  • Hong Jin-Ho;Soh Byung-Soo;Baik Jin-Ah;Shin Hyo-Keun
    • Korean Journal of Cleft Lip And Palate
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    • v.4 no.2
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    • pp.69-78
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    • 2001
  • Alveolar cleft exists in 75% of cleft patients, In alveolar cleft patients, alar base is widening, palatal fistular formation, maxillary growth disturbance & tooth loss of adjacent area is raised, Alveolar bone grafting, especially iliac bone grafting, is a general treatment method. As operation timing, bone grafting is classified with primary, early secondary, secondary, & late secondary, Here we report cleft width, marginal bone height, bone resorption rate, grafted shape & bone densities after secondary iliac bone grafting was done in the Dept. of oral and maxillofacial surgery of chonbuk national university hospital. We compared cleft width to bone resorption rate and grafted shape. Also, alveolar bone densities of grafted and contralateral site was compared with Emago 3 package? (Oral Diagonostic System, The Netherlands), The data obtained were analyzed using Spearman's rho coefficients and sign test with SPSS for window, The results were obtained as follows. 1. As alveolar cleft width is increase, bone resorption rate is, too. This relation showed significant difference(P<.01). 2, In proximal & distal area, alvolar cleft width and bone graft contour after bone grafting had a reverse proportional difference. It was not significant difference(P>.05). 3. After 3 month, in bone density results by using Emago 3 package? with periapical standard view, occlusal view & panoramic view, differences between grafted bone and alveolar bone of contralateral site didn't show a significant difference(P>.05). Thus, differences of bone densities in the alveolar bones didn't exist.

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