• 제목/요약/키워드: Growth disturbance

검색결과 203건 처리시간 0.029초

Long-term outcomes of surgery and radiotherapy for secreting and non-secreting pituitary adenoma

  • Kim, Mi Young;Kim, Jin Hee;Oh, Young Kee;Kim, El
    • Radiation Oncology Journal
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    • 제34권2호
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    • pp.121-127
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    • 2016
  • Purpose: To investigate treatment outcome and long term complication after surgery and radiotherapy (RT) for pituitary adenoma. Materials and Methods: From 1990 to 2009, 73 patients with surgery and RT for pituitary adenoma were analyzed in this study. Median age was 51 years (range, 25 to 71 years). Median tumor size was 3 cm (range, 1 to 5 cm) with suprasellar (n = 21), cavernous sinus extension (n = 14) or both (n = 5). Hormone secreting tumor was diagnosed in 29 patients; 16 patients with prolactin, 12 patients with growth hormone, and 1 patient with adrenocorticotrophic hormone. Impairment of visual acuity or visual field was presented in 33 patients at first diagnosis. Most patients (n = 64) received RT as postoperative adjuvant setting. Median RT dose was 45 Gy (range, 45 to 59.4 Gy). Results: Median follow-up duration was 8 years (range, 3 to 22 years). In secreting tumors, hormone normalization rate was 55% (16 of 29 patients). For 25 patients with evaluable visual field and visual acuity test, 21 patients (84%) showed improvement of visual disturbance after treatment. The 10-year tumor control rate for non-secreting and secreting adenoma was 100% and 58%, respectively (p < 0.001). Progression free survival rate at 10 years was 98%. Only 1 patient experienced endocrinological recurrence. Following surgery, 60% (n = 44) suffered from pituitary function deficit. Late complication associated with RT was only 1 patient, who developed cataract. Conclusion: Surgery and RT are very effective and safe in hormonal and tumor growth control for secreting and non-secreting pituitary adenoma.

Assessing persistence of cruciferous crops in the field

  • Eun Mi, Ko;Do Young, Kim;Ye Seul, Moon;Hye Jin, Kim;In Soon, Pack;Young-Joong, Kim;Kyong-Hee, Nam;Jihyon, Kil;Chang-Gi, Kim
    • 농업과학연구
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    • 제49권3호
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    • pp.655-666
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    • 2022
  • We assessed the persistence of eight major cruciferous crops-leaf mustard, oilseed rape, cabbage, broccoli, cauliflower, Chinese cabbage, turnip, and radish-growing in the field. In the first part of our experiment, we tested the viability of seeds that had been buried at two different soil depths for up to 16 months. We then broadcast seeds over the soil surface and left them undisturbed to investigate the survivorship of the resultant plants over two years. Seed viability was significantly affected by plant taxa and burial depth, but not substantially affected by the duration of burial. Although seeds of leaf mustard had the greatest viability among all crops examined here, the viability rates were significantly lower at 2 cm depth than at 15 cm. Seeds of leaf mustard, oilseed rape, broccoli, turnip, and Chinese cabbage remained viable throughout the 16-month period. A study of plant demography revealed that only leaf mustard and oilseed rape succeeded in producing seeds and overwintering in the undisturbed field. However, neither of those species competed well with other plants long-term and their overall growth and survival rates declined during the evaluation period. In addition, insect herbivory severely decreased the growth of all of these crops. Our results suggest that populations of leaf mustard and oilseed rape do not tend to persist in the field for more than a few years without disturbance and external seed inputs.

유착된 상악 절치의 외과적 처치를 동반한 교정 치료 (Surgically assisted orthodontic treatment of ankylosed maxillary incisor)

  • 손우성;정인교;신상훈
    • 대한치과교정학회지
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    • 제32권4호
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    • pp.257-264
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    • 2002
  • 유착된 치아는 교정력으로 이동되지 않으므로 대부분 발치를 하였지만 어린나이에 치아를 발거하면 치아의 결손과 이에 수반되는 치조골의 소실 때문에 심미적으로 매우 불량해진다. 저자들은 임상적, 방사선 소견으로 유착된 것이 확인된 상악 중절치와 측절치를 각각 의도적인 탈구와 단일치아 골절단술을 시행한 후 약하고 지속적인 힘을 가하여 비교적 양호한 결과를 얻어 이에 대해 보고하고자 한다.

hEPO 유전자의 발현이 조절되는 형질전환 닭의 생산 (Generation of Transgenic Chickens Regulating hEPO Gene Expression)

  • 구본철;권모선;김태완
    • Reproductive and Developmental Biology
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    • 제34권3호
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    • pp.193-199
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    • 2010
  • We report here the production of transgenic chickens that can regulate human erythropoietin (hEPO) gene expression. The glycoprotein hormone hEPO is an essential for viability and growth of the erythrocytic progenitors. Retrovirus vector system used in this study has two features including tetracycline-controllable promoter and woodchuck hepatitis virus posttranscriptional regulator element (WPRE). The former is for to reduce the possibility of physiological disturbance due to constitutional and unregulated expression of hEPO gene in the transgenic chicken. The latter is for maximum expression of the foreign gene when we turn-on the gene expression. A replication-defective Moloney murine leukemia virus (MoMLV)-based vectors packaged with vesicular stomatitis virus G glycoprotein (VSV-G) was injected beneath the blastoderm of non-incubated chicken embryos (stage X). Out of 325 injected eggs, 28 chicks hatched after 21 days of incubation and 16 hatched chicks were found to express the hEPO gene delivered by the vector. The biological activity of the recombinant hEPO in transgenic chicken serum was comparable to its commercially available counterpart. The recombinant hEPO in transgenic chicken serum had N- and O-linked carbohydrate simillar to that produced from in vitro cultured cells transformed with hEPO gene.

임해매립지의 식재지반별 토양 물리·화학적 특성 (Physico-Chemical Properties of Soils at the Ground of Landscape Planting in Reclaimed Land from the Sea)

  • 김도균
    • 한국환경복원기술학회지
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    • 제4권4호
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    • pp.12-18
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    • 2001
  • This study was carried out to analyze physico-chemical properties of soils at the ground of landscape planting in reclaimed land from the sea on Kwangyang Bay, South Korea. Physico-chemical properties of soils at each planting grounds were tested by ANOVA and were significantly(P<0.01) different. The difference came from the soil properties of the covered soil, the disturbance applied to the soil with land use and the accumulation of organic matter after landscape planting. Soil hardness, pH, ECe, Na and K level were in a stable condition at high then low of ground height for landscape planting. Organic matter accumulation was greater at lower planting grounds then top and slope ground of big mounding. The planting grounds of favorable growth for landscape trees were determined as following order : the slope ground and the top ground of big mounding>the ground of medium mounding>the coved ground of improve soil>the lower ground of big mounding>the filled ground of improve soil.

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울릉도 성인봉 원시림의 산림군집구조 (Vegetation Structure of the Songinbong Virgin Forest(Natural Monument) in Ullungdo, Korea)

  • 한봉호;김동완;조현서
    • 한국환경생태학회지
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    • 제12권2호
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    • pp.138-146
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    • 1998
  • 울릉도 성인봉 원시림의 식생구조를 밝히기 위해 400$m^2$(20m$\times$20m)의 조사구 10개를 설치하였다. 성인봉원시림은 우산고로쇠, 너도밤나무가 우점종이었으며 너도밤나무군집. 우산고로쇠-너도밤나무군집. 우산고로쇠군집으로 나누어졌다. 울릉도의 지리적 입지와 식생 특성상 각 군집의 Shannon 종다양도는 0.5150~0.8437로 낮은 편이었다. 상대우점치 분석, 흉고직경급별 분포 분석 등 군집구조 분석 결과, 성인봉 원시림은 성숙한 산림으로 현 상태를 오랜 기간 동안 지속적으로 유지할 것으로 판단되었다. 수목 생장유형 분석 결과, 과거 너도 밤나무림이 우점하던 성인봉 원시림에서 교란에 의해 우산고로쇠의 세력이 확대된 것으로 추정되었다.

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상악골에 생긴 섬유성이형성증의 치료 경험: 안면윤곽술, 부분적 상악골 절제술과 상악동 형성 (Clinical Experience of Maxillary Fibrous Dysplasia: Shaving, Partial Maxillectomy & Maxillary Sinus Formation)

  • 이윤호;주춘승
    • Archives of Plastic Surgery
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    • 제33권2호
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    • pp.259-262
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    • 2006
  • Fibrous dysplasia(FD) of the bone is a slowly progressive, benign disease of unknown cause where normal architectures are replaced with fibrous and osteoid tissue. FD of the maxilla usually manifests as a bony enlargement with painless swelling and bone deformity, contouring to facial asymmetry. The lesion may involve the nasal fossae, orbits, or alveolus bone, causing diverse functional disturbance. Treatment options range from shaving to total maxillectomy and reconstruction depending on the presenting symptoms. Shaving, partial maxillectomy and maxillary sinus formation was performed in 5 patients with fibrous dysplasia in the past 2 years. Follow up period ranged from 1 month to 11 months. Aesthetic appearance, CT findings, and relief from symptoms were compared. In all patients, facial asymmetry was restored to symmetry and nasal obstructive symptoms were improved. With this procedure, expansion of the lesion will be controlled until puberty, preventing the development of new functional disturbances. After puberty, no further treatment can be anticipated due to the growth arrest inherent to the disease.

전압 변동률을 고려한 수도권 전압 안정화 다단계 부하차단 적용 방안 (Multi-level UnderVoltage Load Shedding Scheme Considering Rate of Change of Voltage for Voltage Stability)

  • 이윤환;김태균;김지훈;이병준;강부일;조종만
    • 전기학회논문지
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    • 제58권12호
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    • pp.2335-2341
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    • 2009
  • High technique growth of modem times and high industrial facility in consequence of buildings demand for electric power of an extensive scale with stability supply and maintenance of high quality. But, power system always have risk of network contingency. When power system break out disturbance, it circumstantially happen like uncontrolled loss of load developing from of cascading. Severely which would be raised wide area blackout, plan to prevent, which make stability through a little of load shedding and multi-level UnderVoltageLoadShdding should work. This paper presents target, sensitivity of bus voltage have choose appropriating load shedding location and load shedding decision making logic with considering rate of change of voltage have studied multi-level under voltage load shedding scheme. Calculation of rate of change of voltage applied method of least square. As a result, we are studied an dynamic analysis of 2008 summer peak data. We have been known that network analysis is a little development and developing UnderVoltageLoadShedding scheme.

Comprehensive orthodontic treatment of a young girl with an odontogenic keratocyst and impacted teeth in the mandible

  • Baik, Won-Kyeong;Baik, Hyoung-Seon;Choi, Sung-Hwan
    • 대한치과교정학회지
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    • 제50권1호
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    • pp.63-71
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    • 2020
  • Odontogenic keratocysts (OKCs) are one of the most aggressive cysts in the oral and maxillofacial area because of their high recurrence rate and infiltrative behavior. In growing patients with OKCs, a radical treatment approach might cause numerous complications, including the disturbance of jaw growth and loss of the involved tooth. This case report describes successful comprehensive orthodontic treatment combined with marsupialization of the cyst in a young girl who exhibited an OKC with impacted teeth. The 10-year-old girl presented with an OKC extending from the mandibular symphysis through the left mandibular body, with ectopic impaction of the mandibular left canine and first premolar, as well as congenitally missing bilateral mandibular second premolars. Interestingly, spontaneous improvement of the positions of the ectopic impacted teeth, along with a reduction in the size of the cyst, occurred during marsupialization. The sequential use of removable and fixed appliances enabled orthodontic traction of the impacted teeth. The treatment outcome was stable at 2.5 years after the end of the treatment. We speculate that comprehensive orthodontic treatment combined with marsupialization can be an effective treatment strategy for patients with OKCs, especially when they are encountered in young, growing patients with impacted teeth.

악기능 장치를 이용한 하악 과두 골절의 치험례:1증례에 대한 임상적, 방사선학적 분석 (Non-Surgical Treatment of Mandibular Condylar Fracture with Functional Appliance:Clinical and Radiographic Analysis of 1 Case)

  • 천상득;노재환;송재철;진병로
    • Journal of Yeungnam Medical Science
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    • 제19권2호
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    • pp.144-150
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    • 2002
  • 영남대학교 의과대학 부속병원 치과학교실에서는 악기능 장치를 이용하여 비관혈적 정복술을 시행한 하악 과두 골절 1례에서 양호한 치료 경과를 보였기에 문헌 고찰과 함께 보고하는 바이다. 추후 본 증례에 기초한 다수 증례의 연구가 필요할 것으로 사료된다.

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