• Journal of Life Science
• /
• v.27 no.1
• /
• pp.32-37
• /
• 2017

Cyanidin-3-O-glucoside (C3G) shows anti-inflammatory and antioxidant effects; however, its effect on postprandial blood glucose levels remains unknown. Alpha-glucosidase inhibitors regulate post-prandial hyperglycemia by impeding carbohydrate digestion in the small intestine. Here, the effect of C3G on ${\alpha}-glucosidase$ and ${\alpha}-amylase$ inhibition and its ability to ameliorate postprandial hyperglycemia in streptozotocin (STZ)-induced diabetic mice were evaluated. ICR normal and STZ-induced diabetic mice were orally administered soluble starch alone or with C3G or acarbose. The half-maximal inhibitory concentrations of C3G for ${\alpha}-glucosidase$ and ${\alpha}-amylase$ were 13.72 and $7.5{\mu}M$, respectively, suggesting that C3G was more effective than acarbose. The increase in postprandial blood glucose levels was more significantly reduced in the C3G groups than in the control group for both diabetic and normal mice. The area under the curve for the diabetic mice was significantly reduced following C3G administration. C3G may be a potent ${\alpha}-glucosidase$ inhibitor and may delay dietary carbohydrate absorption.

• Journal of Trauma and Injury
• /
• v.33 no.1
• /
• pp.1-12
• /
• 2020

Purpose: Despite recent developments in the management of trauma patients in South Korea, a standardized system and guideline for trauma treatment are absent. Methods: Five guidelines were assessed using the Appraisal of Guidelines for Research and Evaluation II instrument. Results: Restrictive volume replacement must be used for patients experiencing shock from trauma until hemostasis is achieved (1B). The target systolic pressure for fluid resuscitation should be 80-90 mmHg in hypovolemic shock patients (1C). For patients with head trauma, the target pressure for fluid resuscitation should be 100-110 mmHg (2C). Isotonic crystalloid fluid is recommended for initially treating traumatic hypovolemic shock patients (1A). Hypothermia should be prevented in patients with severe trauma, and if hypothermia occurs, the body temperature should be increased without delay (1B). Acidemia must be corrected with an appropriate means of treatment for hypovolemic trauma patients (1B). When a large amount of transfusion is required for trauma patients in hypovolemic shock, a massive transfusion protocol (MTP) should be used (1B). The decision to implement MTP should be made based on hemodynamic status and initial responses to fluid resuscitation, not only the patient's initial condition (1B). The ratio of plasma to red blood cell concentration should be at least 1:2 for trauma patients requiring massive transfusion (1B). When a trauma patient is in life-threatening hypovolemic shock, vasopressors can be administered in addition to fluids and blood products (1B). Early administration of tranexamic acid is recommended in trauma patients who are actively bleeding or at high risk of hemorrhage (1B). For hypovolemic patients with coagulopathy non-responsive to primary therapy, the use of fibrinogen concentrate, cryoprecipitate, or recombinant factor VIIa can be considered (2C). Conclusions: This research presents Korea's first clinical practice guideline for patients with traumatic shock. This guideline will be revised with updated research every 5 years.

• The KIPS Transactions:PartC
• /
• v.8C no.1
• /
• pp.60-67
• /
• 2001

Multicast Protocol for multimedia service on the Internet can be classified into two types, e.g., source based tree and shared tree according to difference of tree construction method. Shared tree based multicast is known to show outstanding results in the aspect of scalability than source based tree. Generally, There have been lots of researches on the method to satisfy QoS constraints through proper Rendezvous Point (RP) in the shared tree. In addition, as the multicast group members join and leave dynamically in the service time, RP of the shared tree should b be reselected for guranteeing Qos to new member, But, RP reselection method has not been considered generally as the solution to satisfy QoS C constraints. In this paper, new initial RP selection and RP reselection method are proposed, which utilize RTCP (Real Time Control Protocol) report packet fields. Proposed initial RP selection and RP reselection method use RTCP protocol which underlying multimedia application service So, the proposed method does not need any special process for collecting network information to calculate RP. New initial RP selection method s shows better performance than random and topology based one by 40-50% in simulation. Also, RP reselection method improves delay p performance by 50% after initial RP selection according to the member’s dynamicity.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.21 no.1
• /
• pp.28-35
• /
• 2010

In this paper, we designed and fabricated a ultra-wideband(UWB) bandpass filter with a good performance of a stopband, and a notched band in passband. The transformed equivalent circuit of the highpass filter was realized by distributed element. A wide-passband with 3-dB fractional bandwidth of more than 100 % was achieved by using optimum response of the HPF. For improving lower and upper stopband characteristic, a cross coupling between feed lines was employed, which was analyzed by desegmentation technique. In order to reject interference of Wireless LAN and Hyper LAN(5.15~5.825 GHz), the narrow notched(rejection) band was realized by a spurline. The fabricated BPF indicated the passband from 3.1 to 10.55 GHz and the flat group delay of less than 0.94 ns over the entire passband except the rejection band. The filter shown sharp attenuation both inside and outside the band and notched band from 5.2 to 6.12 GHz.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.11
• /
• pp.1-6
• /
• 2019

Multicast is an efficient method for real-time transmission in many multimedia applications. It is important to recover lost packets and to manage multicast groups according to the network status in order to improve the reliability of multicast transmissions. In this paper, we propose a method that can efficiently recover lost packets in a large multicast group. In the proposed method, we create a recovery cluster (RC) using a multicast domain (MD) for recovery of lost packets. In the conventional methods, clusters send a request message for lost packets to the senders in order to recover the packets lost from many multicast applications. This increases packet delay time and overhead because of the feedback messages and retransmitted packets. In the proposed method, we improve these problems using the RC, which consists of many MDs (which have overlay multicast senders), and many cluster heads (CHs). We divide the message into blocks, and divide each block into many segments for packet recovery using the CHs. When packet loss occurs, all CHs share the segment information and recover the lost segments at the same time. Simulation results show that the proposed method could improve the packet recovery ratio by about 50% compared to the conventional methods.

• Quality Improvement in Health Care
• /
• v.20 no.1
• /
• pp.28-40
• /
• 2014

Objectives: Prescriptions for Parkinson's can be dispensed at the outpatient pharmacy. In general, the treatment of Parkinson's disease requires a multitude of drugs, sometimes taken 4 to 6 times a day at specific times as prescribed by the medical practitioner. Said "time-specific therapy" is one of the major reasons of dispensing delay observed at the outpatient pharmacy. Because our establishment lacked a computerized system to support time-specific prescriptions, they were not recognized electronically. They had to be issued and dispensed manually, which required a greater amount of time than the automated process. To solve the problem, a new sig code was developed to handle time-specific prescriptions with a comprehensive automated dispensing system to support it. This study aims to create electronic programs and streamline the process to increase dispensing performance. And thus, ensure greater patient safety and dispensing accuracy within a shorter dispensing time and also increase employee satisfaction through a decreased workload. Methods: After identifying the problems caused by non-electronic prescriptions an automated system that allowed the issuance of time-specific prescriptions was developed. A new sig code was created that could be recognized by the Pharmacy electronic medical program, the label printer to group medications by administration times and the Automatic Tablet Counter(ATC) to count the grouped drugs accordingly. Result: With the new sig code, the practitioner became able to electronically select the times of drug administration while issuing the prescription. This 'time-specific prescription' can now be recognized by the pharmacy electronic medical program, the label printer and the ATC like any other prescription. Conclusion: The developed program started operating on September 2013. Although not all Parkinson's patients have been issued with the new electronic 'time-specific prescription', the overall dispensing process has become more streamlined and accurate. As the medical team continues to integrate the new system in their practice an additional decrease of the dispensing time is predicted. Future program upgrades and other new time-saving approaches are scheduled, which are expected to further increase the service quality of our outpatient pharmacy.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.29 no.7B
• /
• pp.598-612
• /
• 2004

Client requests have increased with the improvement of network resources at client side, whereas network resources at server side could not keep pace with the increased client request. Therefore, it is primary factor of the Qos that efficiently utilize network resources at server side. In this paper, we proposed a new model that peer-to-peer transfer scheme for partial multimedia stream based on CIWP which it decrease server network bandwidth by utilizing client disk resources saves additional server network resources. Especially, adapting Threshold_Based Multicast scheme guarantees to do that data transfer within clients never exceed service time of previous peer by restriction of which data size transferring from previous peer less than data size transferring from server. Peer-to-peer transfer within clients is limited in same group classified as ISPs. Our analytical result shows that proposed scheme reduces appling network resources at server side as utilizing additional client disk resource. furthermore, we perform various simulation study demonstrating the performance gain through comparing delay time and proportion of waiting requesters. As a result, when we compared to Threshold_Based Multicast scheme, the proposed scheme reduces server network bandwidth by 35%.

• Journal of the Korean Institute of Telematics and Electronics C
• /
• v.36C no.10
• /
• pp.17-28
• /
• 1999

In this paper, an ASIC emulation system called ACE (ASIC Emulator) is proposed. It can produce the prototype of target ASIC in a short time and verify the function of ASIC circuit immediately The ACE is consist of emulation software in which there are EDIF reader, library translator, technology mapper, circuit partitioner and LDF generator and emulation hardware including emulation board and logic analyzer. Technology mapping is consist of three steps such as circuit partitioning and extraction of logic function, minimization of logic function and grouping of logic function. During those procedures, the number of basic logic blocks and maximum levels are minimized by making the output to be assigned in a same block sharing product-terms and input variables as much as possible. Circuit partitioner obtain chip-level netlists satisfying some constraints on routing structure of emulation board as well as the architecture of FPGA chip. A new partitioning algorithm whose objective function is the minimization of the number of interconnections among FPGA chips and among group of FPGA chips is proposed. The routing structure of emulation board take the advantage of complete graph and partial crossbar structure in order to minimize the interconnection delay between FPGA chips regardless of circuit size. logic analyzer display the waveform of probing signal on PC monitor that is designated by user. In order to evaluate the performance of the proposed emulation system, video Quad-splitter, one of the commercial ASIC, is implemented on the emulation board. Experimental results show that it is operated in the real time of 14.3MHz and functioned perfectly.

• The KIPS Transactions:PartB
• /
• v.8B no.5
• /
• pp.523-532
• /
• 2001

A Critical issue in the performance of a video-on-demand system is the required I/O bandwidth of the Video server in order to satisfy clients requests, and it is the crucial resource that may cause delay increasingly. Several approaches such as batching and piggybacking are used to reduce the I/O demand on the video server through sharing. Bathing approach is to make single I/O request for storage server by grouping the requests for the same object. Piggybacking is th policy for altering display rates of requests in progress for the same object to merge their corresponding I/O streams into a single stream, and serve it as a group of merged requests. In this paper, we propose a reservation-based hybrid disk bandwidth reduction policy that dynamically reserves the I/O stream capacity of a video server for popular videos according to the loads of video server in order to schedule the requests for popular videos immediately. The performance of the proposed policy is evaluated through simulations, and is compared with that of bathing and piggybacking. As a result, we know that the reservation-based hybrid disk bandwidth reduction policy provides better probability of service, average waithing time and percentage of saving in frames than batching and piggybacking policy.

• Archives of Reconstructive Microsurgery
• /
• v.6 no.1
• /
• pp.96-102
• /
• 1997

The gracilis that is frequently used as a donor of free muscle trasfer is appropriate in the muscular shape and vascular position. This muscle is belonged to the second type of muscle group by the classification of the pattern of muscular nutrient vessel. The adductor branch or first perforating branch of deep femoral artery which supplies the proximal 1/3 of this muscle is a dominant one and this is used for the microscopic anastomosis of muscle or musculocutaneous flap. The minor vascular pedicles which enter the distal 1/3 of this of this muscle are branches of the superficial femoral artery and it is 0.5mm in diameter, 2cm in length with two venae comitantes. These minor pedicles supplies distal half of the gracilis muscle. This island musculocutaneous flap using distal vascular pedicle can be used to cover the defect of soft tissue around the distal femoral supra-condylar area, knee joint and proximal tibial condyle area which cause limitation of motion of knee joint, or in the cases that usual skin graft is impossible. The important operative procedure is as follows; The dissection is carried proximally and distally and the entire gracilis muscle including proximal and distal pedicle is completely dissected. After temporary blocking of the proximal vascular pedicle, the adequate muscle perfusion by the distal pedicle is identified and it is rotated to the recipient site around knee joint. The advantages of this procedure are simple, no need of microscopic vascular anastomoses and no significant functional loss of donor site. Especially in the cases of poor condition of the recipient vessel, this procedure can be used effectively. From 1991 to 1996, we performed 4 cases; complete survival of flap in 3 cases and partial survival of flap with partial necrosis in 1 case. This procedure is though to be useful in the small sized soft tissue defect of distal femoral supra-condylar area, knee joint and proximal tibial condylar area, especially in the defect of anterior aspect which expected to cause limitation of motion of knee joint due to scar contracture. But the problems of this procedure are the diameter of distal vascular pedicle is small and the location of distal vascular pedicle is not constant. To reduce the failure rate, identify the muscular perfusion of distal vascular pedicle after blocking the proximal pedicle, or strategic delay will be helpful.