• 한국지역사회생활과학회지
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• 제18권3호
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• pp.363-368
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• 2007

This study is to find out the antioxidative effect and serum lipid composition of wild grape seed powder in vivo. 20 white Sprague Dawley rats of six weeks old were divided into 2 groups and AIN-93 basic diet, high fat and cholesterol were provided. And they were examined to know how wild grape seed powder worked for antioxidative effect and serum lipid composition. For the comparing group, wild grape seed powder consisting 5% of the diet weight was provided and the quantity of protein, fat, carbohydrate, and cellulose was controlled following the analysis of the ingredients. The rats were fed for four weeks with experimental diet. Serum lipid and the antioxidant enzyme activity in blood and liver microsome were measured after 4 weeks of experiment. The results are as follows; There was no difference between the experimental groups in the initial body weight, final body weight, weight gain and FER. Food intake was higher in the group wild grape seed powder was provided than in the control group(p<0.05). Serum total cholesterol in the control group was significantly higher than that in the group wild grape seed powder was provided.(p<0.05). There was no difference serum HDL cholesterol and LDL cholesterol between the groups. Serum triglyceride showed no significant difference between the groups. In blood, glutanthione peroxidase activity was higher in the group supplemented with wild grape seed powder than in the control group. The glutathione reductase activity of blood showed no difference between the groups. In liver, the glutanthione peroxidase activity was higher in the group supplemented with wild grape seed powder than in the control group(p<0.05). Glutathione reductase activity in liver showed no difference in accordance with the supplementation of wild grape seed powder.

• 대한통합의학회지
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• 제8권3호
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• pp.83-91
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• 2020

Purpose : To identify changes and relationships in the fat mass and obesity associated (FTO) gene polymorphism, body composition, and physical fitness from childhood to adolescence over a three-year period spanning elementary school to middle school (2015-2018) Methods : A total of 84 male student participants were divided into two groups based on FTO genotype: aa+at (group A) and tt (group T) and tracked down. Body composition, cardiovascular endurance, flexibility, muscle strength, power, and other characteristics were measured in the two groups in both 2015 and 2018, respectively, and the changes over the three-year period were analyzed and compared. Results : Increases in height and weight did not differ significantly between the two groups, but body mass index (BMI) was significantly higher in group A (p=.035). With regard to physical fitness, there was no significant difference in flexibility, but cardiovascular endurance, strength, and power were significantly higher in group T (p<.001, p=.063, and p=.040, respectively). Conclusion : Group A is more likely to become obese than group T because of their lower level of physical fitness and increased BMI relative to group T. This result supports previous studies showing that group A has a relatively low level of physical activity and a greater tendency to eat fatty foods as compared with group T. Therefore, we suggest that the FTO gene polymorphism should be identified early and that students educated on diet and physical activity to help prevent adult obesity.

• Journal of Microbiology and Biotechnology
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• 제30권11호
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• pp.1640-1650
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• 2020

Colorectal cancer (CRC) is the leading cause of common malignant neoplasm worldwide. Many studies have analyzed compositions of gut microbiota associated with various diseases such as inflammatory bowel diseases (IBD) and colon cancer. One of the most representative bacteria involved in CRC is enterotoxigenic Bacteroides fragilis (ETBF), a species belonging to phylum Bacteroidetes. We used ETBF colonized mice with azoxymethane (AOM)/dextran sulphate sodium (DSS) and zerumbone, a compound with anti-bacterial effect, to determine whether zerumbone could restore intestinal microbiota composition. Four experimental groups of mice were used: sham, ETBF colonized AOM/DSS group, ETBF colonized AOM/DSS group zerumbone 60 mg kg-1 (ETBF/AOM/DSS + Z (60)), and only zerumbone (60 mg kg^-1)-treated group. We performed reversible dye terminators-based analysis of 16S rRNA gene region V3-V4 for group comparison. Microbiota compositions of ETBF/AOM/DSS + Z (60) group and ETBF colonized AOM/DSS group not given zerumbone were significantly different. There were more Bacteroides in ETBF/AOM/DSS + Z (60) group than those in ETBF colonized AOM/DSS group, suggesting that B. fragilis could be a normal flora activated by zerumbone. In addition, based on linear discriminant analysis of effect size (LEfSe) analysis, microbial diversity decreased significantly in the ETBF colonized AOM/DSS group. However, after given zerumbone, the taxonomic relative abundance was increased. These findings suggest that zerumbone not only influenced the microbial diversity and richness, but also could be helpful for enhancing the balance of gut microbial composition. In this work, we demonstrate that zerumbone could restore the composition of intestinal microbiota.

• 동아시아식생활학회지
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• 제4권1호
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• pp.57-70
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• 1994

The present study was carried out in normal and atherosclerotic New Zealand white(NZW) rabbits, to evaluate the effect of dietary supplementation with Korean pinenut oil, on the total fatty acid composition of red blood cell membranes. Erythrocyte fatty acids of chain lengths ranging fro 12 : 0 to 22 : 6$\omega$3 were identified. In study I, palmitic acid(16 : 0) was found to be the main erythrocyte membranes fatty acid, followed in turn by stearic(18 : 0), oleic(18 : 1), and linoleic acids(18 : 2$\omega$6). There was a large increase in the proportion of 20 : 4$\omega$6 in 10% pinenut oil group on days 40 and 80(compared with control), although the increase was not statistically significant. Most erythrocyte fatty acids were less affected by the types or levels of oils supplemented for periods fo 40 and 80days. In study II,at the end of the dietary treatment, the levels of 12 : 0, 14 : 0, 15 : 0 and 18 : 0 were significantly decreased in the 5% soybean oil/cholesterol group, whereas those of 12 : 0, 14 : 0 and 18 : 0 were significantly decreased, but that of 18 : 2$\omega$6 was significantly increased in the 10% soybean oil/cholesterol group, compared to the cholesterol group. No significant differences in fatty acid composition were seen between the pinenut oil/cholesterol group, whereas the 10% soybean oil/cholesterol group had significantly elevated 18 : 2$\omega$6, compared to the cholesterol group. The proportion of 18 : 4$\omega$6 was significantly raised in the 5% soybean oil/cholesterol and 5% pinenut oil/cholesterol group, and the content of 16 : 1$\omega$7 was significantly lowered in the 5% and 10% soybean/cholesterol groups, compared to the cholesterol group at 10 weeks supplementation. In studies I,II and III, the total proportions of saturated fatty acids were not significantly affected by the types of levels of oils supplemented throughout the study period.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2001년도 추계학술대회(한국공작기계학회)
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• pp.3-7
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• 2001

In this study, the effect of WC and group IV elements on the cutting performance in turning is investigated. The composition of WC was changed from 5 to 20% to determine the effect of WC on the cutting performance of cermet tool. The more WC was added, the longer the tool life of the cermet tool was. The cermet with 20% WC showed the best fracture toughness. The cermet tool with 20% WC showed the best cutting performance among the various WC composition. The effect of group IV elements ; ZrC, ZrN and HfC was also investigated by adding each of them to manufacture the cermet tool with fixed 14% WC composition. The cermet with 1% group IV HfC and 14% WC showed the best cutting performance among the investigated cermet tools.

• 한국컴퓨터정보학회논문지
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• 제29권3호
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• pp.137-146
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• 2024

이 연구는 전신 전기근자극 훈련이 비만 수준에 따른 여성의 신체조성 및 심박변이도에 미치는 영향을 분석하는 것이다. 연구 대상은 폐경 전 여성으로 BMI<25는 BMI-N(n=15), BMI=25~29.9는 BMI-1(n=16), BMI>30은 BMI-2(n=9) 집단으로 분류한 후, 12주간 주당 3회의 전신 전기근자극 훈련을 실시하였다. 실험처치 전·후 신체조성과 심박변이도를 측정하여 반복 이원 변량분석과 대응 표본 t-검정을 실시하였고, 사후검증은 Tukey의 방법을 사용하였다. 유의수준(α)은 0.5로 설정, 다음과 같은 결과를 얻었다. 첫째, Weight, BMI, FFM, FM은 BMI-2 집단이 가장 많이 감소하였고, BMI-1, BMI-N 집단 순으로 감소하였다. %BF와 VF는 BMI-2 집단이 가장 많이 감소하였다. 둘째, BPM은 모든 집단에서 차이가 나타났으며, BMI-2 집단이 가장 크게 감소하였다. SDNN과 RMSSD는 각 집단에서 차이가 나타났으며, 비만 수준에 따른 차이는 없었다. LF, HF 및 LF/HF 비율은 차이가 없었다. 결론적으로, 전신 전기근자극 훈련은 비만수준이 높은 여성들의 체구성 변화와 심장 순환계에 긍정적 효과를 미치는 운동요법이 될 수 있음을 확인하였다.

• 대한한의학회지
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• 제19권2호
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• pp.391-400
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• 1998

This study was to investigate the effects of Bo-Jung-Chi-Seub-Tang administration on body composition, blood biochemistrical factors and hormonal changes during 2 weeks Weight Reduction in TaeKwonDo Athletes. 10 subjects were belong to be in elite athletes of KNUPE. They were divided two groups(administration group and non-administration) by 5 subjects in each group randomly. they were measured about body composition(% Fat, Fat Wt, LBM, TBW), Blood Biochemistrical Factors(glucose, TG, total protein, albumin, BUN, Uric acid, Ca, Pi, Mg) and Hormonal Changes(Renin, Aldosteron). As the results of the experiment, conclusions were made as follows: In terms of % Fat, Fat W.T., Mg, TG, Renin, it was shown significant differences between two groups. Although there were no significant differences, rate of weight reduction and levels of LBM, BUN in Bo-Jung-Chi-Seub-Tang administration group were changed more lower than non-administration group.

• 한국응용과학기술학회지
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• 제3권1호
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• pp.49-55
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• 1986

The purpose of the study was to find an effect of Medium Chain Triglycerids (MCT) diet on cholesterol metabolism in rat. Sprague-Dawley rats were fed two different diets containing MCT(trioctanoate) and corn oil respectively. After feeding to each group for four weeks, the levels of serum and liver cholesterol, the excretion rates of fecal and biliary steroids, and also bile acid composition were investigated. The results obtained from the study are as follows : (1) The average body weight gain in MCT group was almost same as that in the corn oil group. (2) The concentration of serum cholesterol in MCT group was lower than that in the corn oil group. Therefore it is confirmed that the cholesterol lowing action of MCT diet was practically high. (3) The concentrations of liver cholesterol and Triglyceride in MCT group were almost same as that in the corn oil group. Therefore it is thought that the level of liver lipids was not influenced by the difference of diet in this study. (4) The excretion rate of fecal neutral steroid in MCT group was significantly lower than that in the corn oil group, while the rate of fecal bile acid excretion was about same in both MCT and corn oil group. (5) The composition rates of fecal bile acid such as cholic acid, chenodeoxycholic acid and deoxycholic acid, a secondary acid of cholic acid, in MCT group were significantly lower than that in the corn oil group. (6) The excretion rates of biliary cholesterol and bile acid in MCT group were significantly higher than that in the corn oil group, while the composition rates of biliary bile acid such as chenoddeoxycholic acid and deoxycholic acid in MCT group were significantly higher than that in the corn oil group.

• 한국융합학회논문지
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• 제8권1호
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• pp.231-238
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• 2017

본 연구 목적은 20대 비만 여성에서 6주간의 복합운동 적용 시 신체구성변화가 균형능력에 어떠한 영향을 미치는지 알아보고자 하였다. 자발적 참여의사를 밝힌 20대 비만 여성 21명을 Control(no exercise, n=7), Group I(aerobic, n=7), Group II(combined, n=7)으로 무작위 배정하여 매회 50분간 1주일에 5회 총 6주간 시행하였다. 운동 전, 후 및 측정시기에 따른 세 집단 간 신체구성과 균형변화를 SPSS 18.0 ver.을 이용하여 통계분석 하였다. 연구결과, 운동 전에 비해 Group I, II는 체중과 체지방률이 감소하였고, Group II에서만 근육량의 증가와 체질량 지수가 감소하였다(p<0.05). 균형변화는 Group II에서 정적, 동적균형 모두 향상하였으나, Group I은 정적균형만 향상하였다(p<0.05). 따라서, 복합운동프로그램은 신체구성 변화와 근육량 증가를 유발시켜 균형능력 향상에 긍정적 효과를 나타낸 것을 확인할 수 있었다.

• Journal of Nutrition and Health
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• 제25권1호
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• pp.3-11
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• 1992

This paper examines the effects of dietary fats on the fatty acid composition and market enzyme activites during liver damage in 2-acetylaminofluorene treated rats. Weaning Sprague-Dawley male rats were fed the diet of beef tallow(BT source of sturated fatty acid) corn oil(CO source of n-6 fatty acid) and perilla oil(PO source of n-3 fatty acid) at the level of 15% fat. Ten days after feeding 2-acetylaminofluorene(2-AAF) was injected intraperitoneally twice every week at the level of 50mg/kg body weight for 7 weeks. Liver microsomal and cytosolic fractions were collected to determine the microsomal fatty acid composition lipid peroxide(malondialdehyde MDA) contents glucose 6-phosphatase(G6 Pase) activity cytochrome(Cyt) P-450 contents and cytosolic glutathione S-transferase(G6 Pase) activity cytochrome(Cyt) P-450 contents and cytosolic glutathione S-transferase(GST) activity. The fatty acid composition in microsomal fraction was reflected by different dietary fats. By 2-AAF treatment linoleic acids were increased regardless of the diet MDA contents were higher in CO group than it was in BT group. However 2-AAF treatment decreased MDA contents in all dietary groups. G6Pase activity of BT group was higher than those of the other gropus. CO group had the highest Cyt P-450 contents and 2-AAF treatment lowered Cyt P-450 contents only in CO gropu GST activites were higher in CO than in BT group whereas the enzyme activites were increased by 20AAF treatment in all dietary groups. These results suggest that dietary fats and 2-AAF treatment in all dietary groups,. These results suggest that dietary fats and 2-AAF treatment affect microsomal fatty acid composition The enzyme activities concerned with liver damage were influenced differently by dietary fats and 2-AFF treatment Although PO diet contains much more polyunsaturated fatty acids than CO diet PO diet doesn't cause more oxidant stress compared with CO diet in these data.