• Title/Summary/Keyword: Group(Cell) System

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Effects of Autotransfusion Using Cell Saver in Cardiovascular Surgery (심혈관수술에서 cell saver를 이용한 자가수혈)

  • 구자홍
    • Journal of Chest Surgery
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    • v.26 no.4
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    • pp.255-259
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    • 1993
  • The efficacy of the autotransfusion system is a reducing the need of intraoperative and postoperative transfusion in cardiovascular surgery. Between January 1990 and December 1991, we experienced 23 cases of autotransfusion using Haemonetic Cell Saver in cardiovascular surgery [Experimental group]. Another 13 cases which were taken similiar operations without Cell Saver during same period [Control group]. The amounts of blood transfused are 4.23 1.84 units in Control group, 2.82 1.84 units in Experimental group. Postoperatively, both groups showed decreased platelet counts, mild prolongation of prothrombin and partial thromboplastin time compred to preoperative value [P<0.001], but there were no significant differences between two group [P=NS]. Plasma hemoglobin was markedly increased in Experimental group compared with Control group [p<0.05]. In Experimental group, amount of average processed blood by Cell Saver was 700ml of which composition was hemoglobin 17mg/dl, hematocrit 50.0%, RBC 5,590,000/ml, WBC 7500/ml, and platelet 40,000/ml. The culture of the processed blood revealed no growth of the organisms. Conclusively, Cell Saver autotransfusion system is a simple, safe, and cost effective method especially in the cases associated with massive bleeding. However, it requires familiarity with system, gentle manipulation of suction tip, and careful selection of candidates to obtain maximal benefits .

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Effects of Autotransfusion using Cell Saver in Cardiac Surgery (개심술시 자가 수혈체계[Cell Saver]의 이용 효과)

  • 안욱수
    • Journal of Chest Surgery
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    • v.25 no.11
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    • pp.1312-1317
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    • 1992
  • Autologous blood transfusion is a common method of reducing the need for homologous blood transfusion during cardiac operations. Between June 1991 and May 1992, 12 cases [Group I] were experienced autologous blood transfusion using Cell Saver undergoing double valve replacement or redo-valve replacement. Control group [N=12, Group II] was selected to above similar operation during same period. The Cell Saver system [Haemonetics Corp.] was employed for autologous blood transfusion. The blood shed in the operative field before and after cardiopulmonary bypass and remained cardiotomy reservior was aspirated by means of a locally heparinized collecting system. After centrifused salvaged blood, the resulting red cell concentrate reinfused subsequently. The patient receiving autologous blood transfusion required significantly less homologous blood transfusion than their control group. [Group I; 3519 $\pm$ 869, Group II; 4622 $\pm$ 856, Respectively; P=0.005] There were no clinical infections in the autotransfusion group. And there was no apparent intergroup difference of the clinical findings, hematologio datas and coagulation parameters. We conclude the autotransfusion using Cell Saver is effective for reducing of the hom-ologlous blood transfusion in cardiac surgery.

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Recent R&D Trends of Solid Oxide Fuel Cell Power Generation System (고체산화물 연료전지 발전시스템의 최근 연구 개발 동향)

  • Pyo, Seong-Soo;Lim, Tak-Hyoung;Lee, Seung-Bok;Park, Seok-Joo;Song, Rak-Hyun;Shin, Dong-Ryul
    • Journal of the Korean Electrochemical Society
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    • v.12 no.2
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    • pp.119-130
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    • 2009
  • This article reviews recent R&D trends in SOFC development with an emphasis on industries that can produce the SOFC stack and power generation system. SOFC is an electrochemical device that can convert the chemical energy of fuel into the electrical energy with environment friendly system and high efficiency. SOFC power generation system could be classified as the portable power generation system, auxiliary power unit(APU), residential power generation(RPG) and large size distributed power generation. In the case of more than 10kW system, the major R&D trends are focused on the tubular type SOFC system with high efficient and long term stability to meet the commercialization of SOFC power generation system.

Autotransfusion Using Ccell Saver in Cardiac Surgery (개심술에서의 자가수혈기(Cell Saver)를 이용한 자가수혈)

  • 육을수
    • Journal of Chest Surgery
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    • v.28 no.2
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    • pp.125-130
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    • 1995
  • Autotransfusion system is a common method of reducing the need of intraoperative and postoperative homologous blood transfusion in cardiac operation. Between August 1991 and August 1993, a series of 51 adults undergoing open heart surgery was selected. Autotransfusion using Cell Saver [COBE Baylor Rapid Autologous Transfusion System was done with homologous blood transfusion in 15 cases [Group II or without homologous blood transfusion in 17 cases [Group III . The other 19 cases were taken without Cell Saver for control [Group I . The shed blood in the operative field, remained blood in the oxygenator after cardiopulmonary bypass, and blood drained from chest tubes in postoperative care were aspirated by means of a locally heparinized collection system. After the salvaged blood was washed and centrifuged, the processed blood subsequently reinfused. Composition of processed blood by Cell Saver was hemoglobin 16.9gm%, hematocrit 49%, RBC 5,140,000/ml, WBC 670/ml, and platelet 30,000/ml. In three group, hemoglobin, hematocrit, and platelet counts were decreased postoperatively, but no significant differences between three group. Postoperatively, the amounts of drainage from chest tubes was 543$\pm$121ml in Group I, 809$\pm$201ml in Group II, and 631$\pm$147ml in Group III. In Group II, there was large amount of drainage compared with Group I [p<0.05 . The amount of homologous blood transfused was 1116$\pm$219 ml in Group I, 791$\pm$183 ml in Group II [p<0.05 . The homologous blood was not transfused in 17 cases [53% with Cell Saver.Preoperative and postoperative, coagulation parameters showed no significant differences between three group. And there was no complication related to Cell Saver. We conclude that the autotransfusion using Cell Saver is effective for reducing the homologous blood transfusion in cardiac surgery.

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Design and Performance Evaluation for a Fuel Cell/Battery Hybrid Mini-Bus Based on a Simulation (시뮬레이션 기반 연료전지/2차전지 하이브리드 미니버스의 설계 및 성능 평가)

  • Kim, Min-Jin;Kong, Nak-Won;Lee, Won-Yong;Kim, Chang-Soo
    • Journal of Hydrogen and New Energy
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    • v.18 no.1
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    • pp.60-66
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    • 2007
  • In terms of the vehicle efficiency, a fuel cell hybrid system has advantages compared to a conventional internal combustion engine and a fuel cell alone-powered system. The efficiency of the fuel cell hybrid vehicle mainly depends on the maximum power of the fuel cell and therefore it is important to decide the design value of the fuel cell maximum power. In this paper, to estimate the performance of the fuel cell hybrid mini-bus in the design phase the simulator based on the models for the fuel cell stack, the electric battery, the fuel cell balance of plant, the controller, and the vehicle itself is proposed. Additionally, the hybrid mini-bus efficiencies with several different fuel cell powers are simulated for a city driving schedule and are compared on another. Consequently, the proposed simulation scheme is useful to determine the best design value of the fuel cell hybrid vehicles.

Design and Performance Test for a Fuel Cell Ejector to Reduce its Development Cost (개발 비용 감소를 위한 연료전지용 이젝터의 설계 및 성능평가)

  • Kim, Min-Jin;Kim, Dong-Ha;Yu, Sang-Phil;Lee, Won-Yong;Kim, Chang-Soo
    • Journal of Hydrogen and New Energy
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    • v.17 no.3
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    • pp.279-285
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    • 2006
  • Recirculation for the unreacted fuel is necessary to improve the overall efficiency of the fuel cell system and to prevent fuel starvation since the fuel cell for a vehicle application is a closed system. In case of the automotive fuel cell, the ejector which does not require any parasitic power is good for the performance improvement and easy operation. It is essential to design the customized ejector due to the lack of the commercial ejector corresponding to the operating conditions of the fuel cell systems. In this study, the design methodology for the ejector customized to an automotive fuel cell is proposed. The model based sensitivity analysis prevents the time-consuming redesign and reduces the cost of developing ejector. As a result, the customized ejector to meet the desired performance within overall operating range has developed for the PEMFC automotive system.

Effects of Autotransfusion using Cell Saver in Cardiac Surgery (개심술시 Cell Saver 를 이용한 자가수혈의 효과)

  • 정경영
    • Journal of Chest Surgery
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    • v.23 no.2
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    • pp.260-267
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    • 1990
  • During a eight month period[from December, 1988 to July, 1989], a series of 35 adults undergoing redo-valve replacement or coronary artery bypass grafting was selected to an autotransfusion group[n=10] or a control group[n=25]. The Cell Saver System[Haemonetics Corp., Graintree, Mass] was employed for autotransfusion. With this system, all blood shed in the operative field before and after cardiopulmonary bypass and remained in cardiotomy reservoir after cardiopulmonary bypass was aspirated by means of a locally heparinized collecting system. After the salvaged blood was centrifuged, the resulting red cell concentrate subsequently reinfused. The patients receiving autologous blood required significantly less banked homologous blood than their controls[3213k1020 ml and 506051931 ml, respectively: p=0.001] There were no clinical infections in the autotransfusion group, although 40% of the cultures of processed blood were positive. And there was no apparent intergroup difference of the clinical and the hematologic and hemostatic laboratory findings. We conclude that autotransfusion using cell saver is effective for saving the homologous blood transfusion in cardiac surgery.

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Effects of Autotransfusion using Cell Saver in Open Heart Surgery (개심술시 Cell Saver를 이용한 자가수혈의 효과)

  • 윤경찬;최세영;유영선;이광숙;박창권
    • Journal of Chest Surgery
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    • v.31 no.1
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    • pp.28-31
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    • 1998
  • Homologous blood transfusion entails substantial risks, including allergic reactions, transmission diseases such as hepatitis, acquired immunodeficiency syndrome. Autotransfusion system is a common method of reducing the need for homologous blood transfusion during cardiac operation. Between July 1993 and July 1995, a series of 40 patients undergoing open heart surgery was selected to an autotransfusion group(n=20) or a control group(n=20). The cell saver system(AT1000, Electromedics, Englewood, CO, USA) was employed for autotransfusion. With this system, shed blood in operative field during cardiopulmonary bypass(CPB) and remained blood in cardiotomy reservior after CPB was aspirated by means of a locally heparinized collecting system. After centrifuge salvaged blood, the resulting red cell concentrate reinfused subsequently. The amounts of blood loss were 766.5$\pm$121.3 ml in cell saver group, 770.1$\pm$113.6 ml in control group, and there were no significant differences between two groups(P=NS). The amounts of blood transfused were 2.91$\pm$1.72 units in cell saver group, 4.82$\pm$1.72 units in control group. Composition of processed blood by cell saver was hemoglobin 17.4 gm%, hematocrit 56.4%, RBC 5,780,000/ul, WBC 9,900/ul, and platelet 33,000/ul. There was no complication related to cell saver. Conclusively, cell saver autotransfusion system is safe, effective method for reducing the homologous blood trasfusion in cardiac surgery.

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Effects of Bojungikkitang on the immunosuppression induced by methotrexate in rats (보중익기탕(補中益氣湯)이 Lymphocyte와 CD4+ T cell에 미치는 영향(影響))

  • Kim Mi-Ji;Kim Jang-Hyun
    • The Journal of Pediatrics of Korean Medicine
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    • v.12 no.1
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    • pp.211-230
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    • 1998
  • Introduction The effects of Bojungikkitang on the immunosuppression induced by methotrexate in rats were investigated in this experiment. The multiple parameters of immunity assessed in. each rats includes the rate of body weight loss, weight changes in thymus, spleen and axillary lymphnode. The number of lymphocyte and CD4+ T cell count in blood, thymus, spleen and axillary lymphnode were also measured. Methodology Male Sprague-Dawley rats were chosen as an experiment object and were divided into 3 groups by a random selection. Each group consisted 6 rats. The normal group didn't receive any treatment. The control group was administered methotrexate for 4 days. The sample group was administered with both Bojungikkitang and methotrexate for 4 days. The dosage of medication was 2cc/day, 1cc given at 10AM and another 1cc given at 5PM. Results The rate of body weight loss was significantly decreased in the sample group. The weight of thymus was significantly increased in the sample group while the weight of spleen did not show much increase. Blood CD4+ T cell count, thymus lymphocyte count, thymus CD4+ T cell count, spleen lymphocyte count, spleen CD4+ T cell count and axillary lymph node CD4+ T cell count were significantly increased in the sample group while blood lymphocyte count and axillary lymphnode lymphocyte count did not show much increase. Conclusion As one can witness from the above results, administration of Bojungikkitang played potent role in increasing immune system among the rats treated with methotrexate which induces immunosuppression. Overall increase of lymphocyte count and CD4+ T cell count in the sample group with Bojungikkitang effectively proves its ability to boost the immune system.

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An Immune System Modeling for Realization of Cooperative Strategies and Group Behavior in Collective Autonomous Mobile Robots (자율이동로봇군의 협조전략과 군행동의 실현을 위한 면역시스템의 모델링)

  • 이동욱;심귀보
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1998.03a
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    • pp.127-130
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    • 1998
  • In this paper, we propose a method of cooperative control(T-cell modeling) and selection of group behavior strategy(B-cell modeling) based on immune system in distributed autonomous robotic system(DARS). Immune system is living body's self-protection and self-maintenance system. Thus these features can be applied to decision making of optimal swarm behavior in dynamically changing environment. For the purpose of applying immune system to DARS, a robot is regarded as a B cell, each environmental condition as an antigen, a behavior strategy as an antibody and control parameter as a T-call respectively. The executing process of proposed method is as follows. When the environmental condition changes, a robot selects an appropriate behavior strategy. And its behavior strategy is stimulated and suppressed by other robot using communication. Finally much stimulated strategy is adopted as a swarm behavior strategy. This control scheme is based of clonal selection and idiotopic network hypothesis. And it is used for decision making of optimal swarm strategy. By T-cell modeling, adaptation ability of robot is enhanced in dynamic environments.

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