• 보험의학회지
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• 제3권1호
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• pp.233-244
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• 1986

We'd experienced a case of primary hepatoma at medical department, Dae han Kyoyuk Ins. Company January 1985. As it was found very early stage, we made out the case long term-survival possibility unexpectedly. The conclusions we gained, making comparative-analysis of ultrasonic view and operation's view are as follows; 1. By ultrasonography, echogenicity of tumor was increased type as compared with liver parenchyme. 2. The margin of the primary hepatoma by ultrasonography encapsulated well and the extraction after operation was same. 3. The boundary of tumor was clear. 4. The space-occupying lesion in liver was solitary. 5. The affected site was left lobe of the liver. 6. We couldn't discover a little fluid echo in upper abdomen on the ultrasonography, but could see in the cul-de-sac area and it accorded with the gross finding during laparotomy. 7. The case was cholangiocarcinoma in view of pathologic histology. 8. After the operation of lobectomy. the prognosis which was passed a months was very satisfactory and she exists until present.

• 한국임상수의학회지
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• 제26권5호
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• pp.504-507
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• 2009

An 1-year old male siberian tiger showing severe vomiting and blackish and frothy diarrhea for 3 days were dead in Seoul Zoo. Gross finding at necropsy were small amount of blood were found in abdominal cavity and intestine. In small and large intestine, there were necrosis and detachment epithelial cell of intestinal mucosa in histopathology. The presence of feline panleukopenia virus (FPV) antigen was detected by PCR. In microbiology, E.coli and Enterococcus faecalis were isolated from the stool. This case was diagnosed in death induced by FPV infection according to CBC, histopathology and PCR.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2001년도 추계학술대회 및 정기총회
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• pp.25-25
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• 2001

An example of lymphoblastic lymphosarcoma was diagnosed in a 7-year-old male brown bear (Ursus arctos) that died after having a 7-month history of depression, anorexia and watery diarrhea. Grossly the mesenteric lymph nodes were enlarged to approximately 4 to 6 times their normal size and histologically diagnosed as lymphoblastic lymphosarcoma. The small intestinal mucosa was corrugated and had severe mural thickening due to infiltrated neoplastic cells. Hepatic metastasis was also noted. the mother of this bear which died at the age of 20 also had similar gross changes on necropsy, but histological examination was not performed at that time and therefore the exact type of neoplasm remained to be determined. Since the daughter also died of neoplasm, genetic factor could be suspected in this family. This is the first reported case of lymphosarcoma in Ursidae in Korea. As an incidental finding, endogenous lipid pneumonia was noted in the lung.

• Journal of Gastric Cancer
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• 제15권1호
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• pp.68-73
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• 2015

Gastric cancer that mimics a submucosal tumor is rare. This rarity and the normal mucosa covering the protuberant tumor make it difficult to diagnosis with endoscopy. We report two cases of advanced gastric cancer that mimicked malignant gastrointestinal stromal tumors preoperatively. In both cases, the possibility of cancer was not completely ruled out. In the first case, a large tumor was suspected to be cancerous during surgery. Therefore, total gastrectomy with lymph node dissection was performed. In the second case, the first gross endoscopic finding was of a Borrmann type II advanced gastric cancer-like protruding mass with two ulcerous lesions invading the anterior wall of the body. Therefore, subtotal gastrectomy with lymph node dissection was performed. Consequently, delayed treatment of cancer was avoided in both cases. If differential diagnosis between malignant gastrointestinal stromal tumor and cancer is uncertain, a surgical approach should be carefully considered due to the possible risk of adenocarcinoma.

• Toxicological Research
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• 제27권4호
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• pp.261-267
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• 2011

Artemisia iwayomogi, a member of the Compositae, is a perennial herb easily found in Korea and used as a traditional medicine to treat liver disease. AIP1, a water-soluble carbohydrate fraction from Artemisia iwayomogi, showed anti-tumor and immuno-modulating activities in animal studies. A subacute toxicological evaluation of AIP1 was performed for 4 weeks in ICR mice. After administration of AIP1 (0, 20, 100, 500 mg/kg/day), the clinical signs, mortalities, body weight changes, hematology, blood clinical biochemistry, urinalysis, organ histopathology, organ weights and gross finding were examined. The results showed that there were no significant differences in body weight changes, food intakes, water consumptions, or organ weights among different dose groups. Also we observed no death and abnormal clinical signs during the experimental period. Between the groups orally treated with AIP1 and the control group, there was no statistical significance in hematological test or serum biochemical values. Histopathological examination showed no abnormal changes in AIP1 groups. These results suggest that no observed adverse effect level (NOAEL) of the oral administration of AIP1 for 4 weeks was considered to be more than 500 mg/kg/day in mice under the condition investigated in current study.

• The Journal of Asian Finance, Economics and Business
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• 제8권5호
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• pp.649-656
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• 2021

This paper aims to examine the moderating role of bank competition on the effect of liquidity creation on bank capital. We measure bank competition using the Lerner index approach, liquidity creation using the Catfat approach, and bank capital using the capital to total asset ratio approach. This test also considers control variables from bank-specific factors such as Return on Assets, Loan to Deposit Ratio, and Non-Performance Loans as well as macroeconomic factors such as Gross Domestic Product, inflation, and Bank Indonesia interest rates. The sampling technique used was purposive sampling. The data sample obtained was 96 banks from a population of 114 banks in Indonesia which consistently operated during the period 2008-2018. Hypothesis testing uses panel data regression analysis techniques through the first model of the Hayes method. The results show that the negative effect of liquidity creation on bank capital depends on competition. We found that bank competition at any level (low, medium, high) negatively moderates (weakens) the effect of liquidity creation on bank capital in all banks. This finding is consistent with the view that banks may strengthen their capital in response to bank competition which may decrease the level of bank liquidity creation.

• The Journal of Asian Finance, Economics and Business
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• 제8권3호
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• pp.781-791
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• 2021

This study aims to analyze the relationship between the business cycles of the ASEAN +3 countries. In addition, the effects of the spillover value on the coincident indicators are determined. This study employs secondary data and uses multivariate time series of five ASEAN countries, namely, Indonesia, Malaysia, Singapore, Thailand, and the Philippines. The proxy was the real gross domestic product (GDP) collected annually from the CEIC, the IMF, and the World Bank for the period from 1964 to 2016. The data was plotted against two time periods, 1964-1998 as the pre-crisis period, and 1999-2016 as the post-crisis period. The index data was changed to the base year 2010. The data was subsequently separated from the trends and the cyclic components. The cyclic components were obtained by using Hondrick-Prescott filter, and them were further analyzed. The analytical method used was Contemporaneous and Cross-Correlation tools. The results showed that, before and after the crisis, the value of the business cycle correlation between ASEAN +3 countries was stronger and moved together at the same level of lag value. The implication of this research was an initial finding of the ASEAN +3 countries' prerequisites for the formation of a common currency.

• Childhood Kidney Diseases
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• 제7권2호
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• pp.150-156
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• 2003

목적 : IgA 신병증의 임상 및 병리학적 소견의 비교를 통해서 IgA 신병증의 신조직 소견을 예측할 수 있는 인자를 찾아봄으로써 신생검 시기를 결정하는데 도움이 될 수 있는 지표를 찾아본다. 방법 : 원주기독병원에서 신생검상 IgA 신병증으로 확인된 40례를 대상으로 후향적 연구를 시행하였다. 결과 : 40명의 환자 중 크레아티닌이 1.5 mg/dL 이상을 보인 1명은 추적 관찰이 안되었고 나머지 39명 중 2명에서는 혈중크레아티닌이 1.5mg/dL 이상으로 진행하였으며 그 중의 한명은 진단 후 2년 7개월만에 말기신부전으로 진행하였다. WHO 분류에 따르면 class I이 15명, class II가 14명, class III가 7명, classs IV가 3명, class V 0명이었다. 육안적 혈뇨군에서 현미경적 혈뇨군보다 class I과 class II의 비율이 의미있게 높았다(P<0.02). 세뇨관간질 소견만을 분류해 보았을 때 grade 1은 24명, grade 2는 4명, grade 3는 8명, grade 4는 3명이었다. 세뇨관간질의 변화가 심해질수록 24시간 요단백/알부민 비율이 증가하였다(r=-0.32, P<0.05) 혈청 크레아티닌치가 0.79 mg/dL 이하인 경우 세뇨관간질소견이 경하였으며, 크레아티닌치가 1.13 mg/dL 보다 큰 경우 세뇨관간질병변이 심하였다. 육안적 혈뇨군에서 혈청 크레아티닌치는 현미경적 혈뇨군에 비해 낮았고(0.78 vs 1.09 mg/dL)(P=0.027), 혈청 IgA 치가 높았으며(316.3 vs 198.8mg/dL)(P=0.027), class I과 II의 낮은 WHO 분류 class를 보였다(23 vs 4)(P=0.029). 결론 : IgA 신병증 환자에서 혈청크레아티닌이 0.79 mg/dL 이하, 육안적 혈뇨, 높은 24시간 urine protein/albumin 비율을 보이는 경우 경한 신조직 소견을 보임으로 이런 소견을 보이는 경우 신조직 생검 시기를 미룰 수 있을 것으로 사료된다.

• 한국농림기상학회지
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• 제12권2호
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• pp.107-121
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• 2010

본 연구에서는 한반도의 주요 생태계인 활엽수림과 농경지에서 지면 모형 JULES(Joint UK Land Environment Simulator)으로 모의한 총일차생산량 (Gross Primary Productivity: GPP)과 생태계 호흡량 (ecosystem respiration: RE)의 수치 모사 결과에 영향을 미치는 주요 모수를 파악하였으며, 민감한 모수에 대해 실측자료를 사용함에 따른 모형 예측력의 개선 정도를 평가하였다. 민감도 실험의 결과, 활엽수림과 농경지에서 모두 JULES로 모의한 GPP는 잎 내부의 질소농도와 리불로오스이인산(RuBP) 카르복실화의 최대 속도에 가장 민감하였다. RE는 활엽수림에서는 목질부 탄소량과 엽면적지수를 연결시켜주는 상수에 가장 민감하였다. 반면에 농경지에서 수치모사된 RE는 GPP와 같이 각각 잎 내부의 질소 농도와 RuBP 카르복실화의 최대 속도에 가장 민감하였다. JULES로부터 제공된 모수의 값으로 모의된 두 지역의 GPP와 RE는 모두 관측값에 비해 과대평가되었다. 특히 활엽수림에서 GPP가 가장 민감하게 반응했던 잎 질소 농도의 실제 관측값이 모형에서 사용하는 기존 설정값의 50% 이하임을 고려할 때 모형에서 설정된 모수의 값으로 탄소 순환을 수치 모사할 경우에 모수의 기존 설정값과 실제값의 차이가 모형의 과다모의에 상당한 영향을 미침을 확인할 수 있었다. 따라서 한반도 탄소순환의 현실적인 모의를 위해서는 모형에서 요구되는 생물리학적 정보가 한반도 다양한 식생 기능 형태를 현실적으로 잘 반영하는지를 확인해야 할 뿐 아니라 지속적인 현장 관측을 통해서 생물리학적 정보와 관련된 자료기반을 마련하는 것이 중요하다.

• Childhood Kidney Diseases
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• 제4권2호
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• pp.154-160
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• 2000

IgA 신병증은 메산지움에 면역글로불린 A가 침착되는 질환으로 소아 연령에서 혈뇨의 흔한 원인 질환이며, 급성 감염후 사구체신염은 IgA 신병증 다음으로 소아 연령에서 흔한 혈뇨의 원인이다. IgA 신병증과 급성 감염후 사구체신염의 병태생리학적 기전은 아직 명확하게 밝혀지지 않고 있다. 그러므로 이 질환들 간의 병태생리학적 연관관계, 즉 연쇄상구균 감염이 IgA 신병증의 유발 혹은 악화 인자가 될 수 있는지, 또는 임상양상과 예후에도 어떤 영향을 미칠 수 있는지에 대해서는 더욱 알려진 것이 없다. 저자들은 임상적 및 병리학적 소견으로 IgA 신병증에 병발한 급성 연쇄상구균 감염후 사구체 신염으로 진단할 수 있는 증례 2례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.