• 제목/요약/키워드: Grey Literature

검색결과 48건 처리시간 0.023초

Disinfectant effectiveness of chlorhexidine gel compared to sodium hypochlorite: a systematic review with meta-analysis

  • Theodoro Weissheimer;Karem Paula Pinto;Emmanuel Joao Nogueira Leal da Silva;Lina Naomi Hashizume;Ricardo Abreu da Rosa;Marcus Vinicius Reis So
    • Restorative Dentistry and Endodontics
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    • 제48권4호
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    • pp.37.1-37.17
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    • 2023
  • This study aimed to compare the disinfectant ability of chlorhexidine (CHX) gel and sodium hypochlorite (NaOCl). Systematic searches were conducted from inception until December 8th, 2022 (MEDLINE/PubMed, Cochrane Library, Web of Science, Scopus, Embase, and Grey Literature databases). Only randomized clinical trials were included. The revised Cochrane risk of bias tools for randomized trials were used to assess the quality of studies. Meta-analyses were performed. The overall quality of evidence was assessed through the Grading of Recommendations Assessment, Development, and Evaluation tool. Six studies were included. Five had a low risk of bias and 1 had some concerns. Three studies assessed bacterial reduction. Two were included in the meta-analysis for bacterial reduction (mean difference, 75.03 [confidence interval, CI, -271.15, 421.22], p = 0.67; I2 = 74%); and 3 in the meta-analysis for cultivable bacteria after chemomechanical preparation (odds ratio, 1.03 [CI, 0.20, 5.31], P = 0.98; I2 = 49%). Five studies assessed endotoxin reduction. Three were included in a meta-analysis (mean difference, 20.59 [CI, -36.41, 77.59], p = 0.48; I2 = 74%). There seems to be no difference in the disinfectant ability of CHX gel and NaOCl, but further research is necessary.

Does photobiomodulation on the root surface decrease the occurrence of root resorption in reimplanted teeth? A systematic review of animal studies

  • Theodoro Weissheimer;Karolina Frick Bischoff;Carolina Horn Troian Michel;Bruna Barcelos So;Manoela Domingues Martins;Matheus Albino Souza;Ricardo Abreu da Rosa;Marcus Vinicius Reis So
    • Restorative Dentistry and Endodontics
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    • 제48권3호
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    • pp.24.1-24.16
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    • 2023
  • This review aimed to answer the following question "Does photobiomodulation treatment of the root surface decrease the occurrence of root resorption in reimplanted teeth?" Electronic searches were performed in the MEDLINE/PubMed, Cochrane Library, Scopus, Web of Science, Embase, and Grey Literature Report databases. Risk of bias was evaluated using SYRCLE Risk of Bias tool. The Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) tool was used to assess the certainty of evidence. In total, 6 studies were included. Five studies reported a reduced occurrence of root resorption in teeth that received photobiomodulation treatment of the root surface prior to replantation. Only 1 study reported contradictory results. The photobiomodulation parameters varied widely among studies. GRADE assessment showed a low certainty of evidence. It can be inferred that photobiomodulation treatment of the root surface prior to replantation of teeth can reduce the occurrence of root resorption. Nonetheless, further clinical studies are needed.

The prevalence of apical periodontitis in patients prior to hematopoietic cell transplantation: a systematic review

  • Letícia Taina de Oliveira Lemes;Carolina Horn Troian-Michel;Theodoro Weissheimer;Marcus Vinicius Reis So
    • Restorative Dentistry and Endodontics
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    • 제49권2호
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    • pp.22.1-22.12
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    • 2024
  • Objectives: This systematic review addressed the question: "What is the prevalence of apical periodontitis in patients prior to hematopoietic cell transplantation?" Materials and Methods: A systematic search was conducted in MEDLINE/PubMed, Cochrane Library, Scopus, Web of Science, Embase, and Grey Literature Report. Eligibility criteria were based on the condition, content, and population strategy: the condition was the radiographic prevalence of apical periodontitis, the content comprised patients scheduled for hematopoietic stem cell transplantation, and the population consisted of adult and pediatric patients. The revised Risk of Bias in Nonrandomized Studies of Exposure tool was used to assess the quality of studies. The Grading Recommendations Assessments, Development, and Evaluation (GRADE) tool was used to assess the quality of evidence. Results: Eight studies were included in this review. The average number of patients with apical periodontitis was 15.65% (range, 2.1%-43.34%). One study was classified as having a very high risk of bias, 1 with a high risk of bias, and 6 with some concern for bias. GRADE analysis showed a very low certainty of evidence. Significant limitations concerning the absence of control over confounding variables were identified. Conclusions: With the caveat of the very low quality of evidence in the studies reviewed, there was a low to moderate prevalence of apical periodontitis in patients prior to undergoing hematopoietic cell transplantation.

약인성 간손상의 원인물질에 관한 국내연구의 체계적 고찰 (Systematic Review of the Cause of Drug-Induced Liver Injuries in Korean Literature)

  • 윤영주;신병철;이명수;조성일;박재현;이혜정
    • 대한한의학회지
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    • 제30권2호
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    • pp.30-45
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    • 2009
  • Background: The safety of herbal products is an important issue in Korea. It is more complicated because of the concomitant use of conventional western drugs and herbal medicine, including prescribed medicine, folk herbs and food supplements. Although both western and traditional Korean medical doctors have studied on the safety of HMP, their results did not show relevant or consistent conclusions because of the poor quality of studies, including bias. Objectives: The aim of this study was to review the studies in Korea related to drug induced liver injury (DILI) systematically. We tried to estimate the proportion of causative materials of DILI and evaluate the clinical difference of DILIs from different materials. Methods: Systematic searches were performed on MedRIC and MEDLIS in Korea. The extraction of data as well as selective screening of the studies was carried out independently by two of the authors. There were no restrictions on the types of publication, including grey literature. Results: Twenty-one articles were included. Of them only 7 adapted prospective design and only 6 were published in peer-reviewed journals. The proportion of conventional drugs associated with hepatotoxic injuries in all DILI ranged from 15.8% to 83.3% and that of herbal medicine was from 28.9% to 44.7%. However, the criteria for herbal medicine were not clearly defined and concomitant medications were not fully investigated in most studies. There were limited objective data in the clinical differences of liver injuries from different materials and their results were conflicting. Conclusions: The causality assessments regarding DILI of herbal medicine were not performed properly and causative materials were misclassified in most of the studies published in Korea. These make the safety issue still ambiguous because of the limitations and lack of objectivity of the studies. More rigorous studies are required for clearly addressing these conflicting issues with cooperative investigation between traditional Korean and western medicine.

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선발된 아프리카와 아시아 국가들을 위한 가축유전자원 정보시스템 구축 (Country based Domestic Animal Genetic Resource Information System (C-DAGRIS) for Selected African and Asian Countries)

  • ;;;김동훈;조경래;정현정;;오성종
    • 한국수정란이식학회지
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    • 제29권1호
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    • pp.29-33
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    • 2014
  • 재래가축의 유전자원(FAnGH)의 유전학적 및 표현형적인 특성과 다양성에 대한 정확한 정보는 가축의 현재와 미래의 지속 가능한 이용 및 보존에 중요한 역할을 한다. 본 논문은 과제에 참가한 각 나라별로 목적, 구조, 기능, 내용, 이용성 그리고 미래의 전망 등을 국제축산연구소의 각국별 재래가축 유전자원 정보시스템(DAGRIS)이라는 데이터베이스에 기술하였다. 이 DAGRIS는 전자 데이터베이스로 개발도상국의 연구자, 정책 담당자, 개발 실행자, 교육자, 학생 그리고 농업인들의 요구에 부합되게 설계되었다. 또한 각국의 선발된 가축유전자원(FAnGR)의 기원, 분포, 다양성, 현재 사용도 및 상태 등에 관한 과거와 현재의 연구 결과로부터 논문으로 게재되거나, 문헌 등을 쉽게 접근하기 좋게 개발되었으며, 영어와 불어 사용자를 위하여 영어와 불어로 c-DAGRIS의 국가별 모듈을 개발하고 사용될 수 있게 만들었다.

지역사회 기반 생태관광 개발에서 다양한 이해 관계자들의 참여 기회와 도전: 가나 Boabeng-Fiema 원숭이 보호구역 사례를 중심으로 (Opportunities and Challenges for Multi-Level-Stakeholder Participation in Community-Based Ecotourism Development: The Case of the Boabeng-Fiema Monkey Sanctuary, Ghana)

  • 빅터 오우수;야우 아지만 보아포
    • 한국경제지리학회지
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    • 제21권1호
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    • pp.53-68
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    • 2018
  • 지역사회 기반 생태관광(CBE)은 적절히 설계된다면 사회 경제적 복지를 증진하고 생태 자원을 유지하기 위한 실질적인 방법이 될 수 있다. 이는 특히 개발도상국의 성장과 발전 측면에서 주목할 만하다. 본 연구는 아프리카 가나의 Boabeng-Fiema 원숭이 보호구역 사례를 통해, 전통적인 지역사회 기반 관리 시스템을 지역사회 참여, 공정성, 포괄성 및 다양한 이해관계자들의 파트너쉽 관점에서 평가한다. 본 연구의 분석을 위해서는 심층인터뷰와 질적 자료를 담고 있는 선행연구 분석 기법이 사용되었다. 연구 결과에 따르면, 다수의 인터뷰 대상자가 전통적인 지역사회 기반 시스템이 성공적이라 평가할 수 있다. 그 이유에 대해서 인터뷰 대상자들은 규범, 문화 및 종교적 관습들을 꼽았다. 또한, CBE를 통해 얻은 생계 수단의 증가는 지역 사회의 수용과 참여를 높였다. 하지만 보호구역은 인구 증가 등의 성공을 낳으면서도 동시에, 토지 부족 등의 문제들 또한 낳은 것으로 나타났다. 본 연구는 홈스테이(homestay) 도입, 공예 산업 개발 등을 통해 생계 수단 다양화를 대안으로 제시한다.

A Study on the Costume of The Korean-Chinese Women in Yanbian, China - Focusing on 1990′s -

  • Zhang, Shun-Ai;Kim, Jin-Goo
    • The International Journal of Costume Culture
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    • 제4권1호
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    • pp.25-33
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    • 2001
  • This study is to analyze Korean-Chinese women's Costume in Yabian with factors such as reform opening-up, economic growth, change of social values, development of technology, more education opportunities and influence of mass media. It divides the 1990's into two halves. Photos, interview, observation and relevant literature were used for this study. Even though economy grew rapidly, they needed to purchase daily goods other than clothes. In a way that they preferred practicality, it showed somewhat it was still developing. The trend in the first half of the 1990's was characterized : first, Synthetic or artificial fibers and ready-made suits were popular ; second, there still remained the men's style ; third, they wore Tanrikoo(彈力袴), Tisingkoo(體型袴), Jiaotakoo(脚袴) because of its properties of activeness and comfort ; fourth, shoulders looked ore prominent with pads as they were used in Chungsanfoo(中山服) ; fifth, clothes in grey and dark blue was in fashion ; sixth, they wore hand-made knit vests and sweaters and often mountain-climbing gears for its light and warm quality ; seventh, along with opening-up, various materials and colorful clothes were in style, which satisfied women's desire for beauty. They decorated Hanbok(韓服), using sleeves with colors, golden ornaments, flower patterns embroidery, materials of different color in collar and tie and dyes of sleeves and skirts. In the first half of the 1990's when the opening-up was beginning, there were diverse styles and colors in fashion, yet not close to good quality. As the economy grew, the second half of the 1990's was characterized by good palate, individuality, favouritism on foreign goods, rapid change of fashion. For instance, fur coat and woolen fabric were favored. Economic growth led to abundance of cloth, dyes and decorative materials. In addition, people possessed more clothing and it was possible for them to wear both Hanbok and wedding dress in wedding ceremony. People placed their standards on competency and financial ability rather than ideology. Worship disappeared and individuality arose. Therefore, apparel functioned not only as protection but as suits with aesthetic purpose. This resulted in introduction of bold style, imitation of western countries and extension of use of Hanbok. With the help of mass media, transportation, telecommunication, contact with Korean company and civilians, Korean and western cultures, through Korea, were accepted. Change in structure of economic status caused excessive spending and more educational opportunities that enabled people to accept foreign culture quickly. Values moved onto new, beautiful and better characteristics. it was possible to have suits ready-made due to improvement of mass production and cotten, wool, linen, silk became popular owing to technology. New technology, the bases of mass consumption, increased possession of clothing and accelerated change of fashion. In summary, women's Costume in Yanbian were affected by the factors in economy, politics, culture contact as well as change of society and technology.

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Influence of the root canal filling technique on the success rate of primary endodontic treatments: a systematic review

  • Daniel Feijolo Marconi ;Giovana Siocheta da Silva ;Theodoro Weissheimer;Isadora Ames Silva ;Gabriel Barcelos So;Leonardo Thomasi Jahnke ;Jovito Adiel Skupien ; Marcus Vinicius Reis So ; Ricardo Abreu da Rosa
    • Restorative Dentistry and Endodontics
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    • 제47권4호
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    • pp.40.1-40.18
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    • 2022
  • Objectives: This study aimed to investigate the influence of different obturation techniques compared to cold lateral compaction on the success rate of primary non-surgical endodontic treatments. Materials and Methods: Systematic searches were performed for studies published up to May 17th, 2022 in MEDLINE/PubMed, Cochrane Library, Web of Science, Scopus, EMBASE, and Grey Literature Reports. Randomized clinical trials and nonrandomized (nonrandomized clinical trials, prospective or retrospective) studies that evaluated the success rate of primary non-surgical endodontic treatments obturated with the cold lateral compaction (control) and other obturation techniques were included. The revised Cochrane risk of bias tools for randomized trials (RoB 2) and nonrandomized studies of interventions (ROBINS-I) were used to evaluate the risk of bias. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) tool was used to evaluate the certainty of evidence. Results: Eleven studies (4 randomized clinical trials (RCTs), 4 prospective, and 3 retrospectives) were included. Two RCTs were classified as having some concerns risk of bias and 2 as a low risk of bias. Two nonrandomized studies were classified as having a critical risk of bias and 5 as having a moderate risk of bias. The GRADE analysis demonstrated a very low to moderate certainty of evidence. Conclusions: This systematic review generally evidenced no differences in the success rate of primary non-surgical endodontic treatments when the cold lateral compaction technique and other obturation techniques are performed. Further well-designed studies are still necessary.