• Bulletin of the Korean Chemical Society
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• 제30권9호
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• pp.1981-1984
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• 2009

Subcellular localization of protein kinase often plays an important role in determining its activity and specificity. Protein kinase C (PKC), a family of multi-gene protein kinases has long been known to be translocated to the particular cellular compartments in response to DAG or its analog phorbol esters. We used C-terminal green fluorescent protein (GFP) fusion proteins of PKC isoforms to visualize the subcellular distribution of individual PKC isoforms. Intracellular localization of PKC-GFP proteins was monitored by fluorescence microscopy after transient transfection of PKC-GFP expression vectors in the HeLa cells. In unstimulated HeLa cells, all PKC isoforms were found to be distributed throughout the cytoplasm with a few exceptions. PKC$\theta$ was mostly localized to the Golgi, and PKC$\gamma$, PKC$\delta$ and PKC$\eta$ showed cytoplasmic distribution with Golgi localization. DAG analog TPA induced translocation of PKC-GFP to the plasma membrane. PKC$\alpha$, PKC$\eta$ and PKC$\theta$ were also localized to the Golgi in response to TPA. Only PKC$\delta$ was found to be associated with the nuclear membrane after transient TPA treatment. These results suggest that specific PKC isoforms are translocated to different intracellular sites and exhibit distinct biological effects.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권10호
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• pp.4724-4747
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• 2016

To efficiently reduce on-grid energy consumption, the admission control algorithm in the hybrid energy powered cellular network (HybE-Net) with base stations (BSs) powered by on-grid energy and solar energy is studied. In HybE-Net, the fluctuation of solar energy harvesting and energy consumption may result in the imbalance of solar energy utilization among BSs, i.e., some BSs may be surplus in solar energy, while others may maintain operation with on-grid energy supply. Obviously, it makes solar energy not completely useable, and on-grid energy cannot be reduced at capacity. Thus, how to control user admission to improve solar energy utilization and to reduce on-grid energy consumption is a great challenge. Motivated by this, we first model the energy flow behavior by using stochastic queue model, and dynamic energy characteristics are analyzed mathematically. Then, fuzzy logic based admission control algorithm is proposed, which comprehensively considers admission judgment parameters, e.g., transmission rate, bandwidth, energy state of BSs. Moreover, the index of solar energy utilization balancing is proposed to improve the balance of energy utilization among different BSs in the proposed algorithm. Finally, simulation results demonstrate that the proposed algorithm performs excellently in improving solar energy utilization and reducing on-grid energy consumption of the HybE-Net.

• Journal of Communications and Networks
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• 제16권2호
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• pp.121-129
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• 2014

The trend of an increasing demand for a high-quality user experience, coupled with a shortage of radio resources, has necessitated more advanced wireless techniques to cooperatively achieve the required quality-of-experience enhancement. In this study, we investigate the critical problem of rate splitting in heterogeneous cellular networks, where concurrent transmission, for instance, the coordinated multipoint transmission and reception of LTE-A systems, shows promise for improvement of network-wide capacity and the user experience. Unlike most current studies, which only deal with spectral efficiency enhancement, we implement an optimal rate splitting strategy to improve both spectral efficiency and energy efficiency by exploring and exploiting cooperation diversity. First, we introduce the motivation for our proposed algorithm, and then employ the typical cooperative bargaining game to formulate the problem. Next, we derive the best response function by analyzing the dual problem of the defined primal problem. The existence and uniqueness of the proposed cooperative bargaining equilibrium are proved, and more importantly, a distributed algorithm is designed to approach the optimal unique solution under mild conditions. Finally, numerical results show a performance improvement for our proposed distributed cooperative rate splitting algorithm.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2018년도 춘계학술발표대회
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• pp.85-87
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• 2018

Motivating by two promising technique of 5G, namely D2D and Edge computing, and the above mentioned problem of the current joint studies, We believe that more study is needed on the benefits of joining these two techniques in a single framework by more precisely taking into account the energy needed to computation, sending data, receiving data and as a result achieving more realistic energy efficiency in 5G cellular networks.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권12호
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• pp.5712-5728
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• 2017

Recently, there are many studies, that considering green wireless cellular networks, have taken the energy consumption of the base station (BS) into consideration. In this work, we first introduce an energy consumption model of multi-mode sharing BS powered by multiple energy sources including renewable energy, local storage and power grid. Then communication load requests of the BS are transformed to energy demand queues, and battery energy level and worst-case delay constraints are considered into the virtual queue to ensure the network QoS when our objective is to minimize the long term electricity cost of BSs. Lyapunov optimization method is applied to work out the optimization objective without knowing the future information of the communication load, real-time electricity market price and renewable energy availability. Finally, linear programming is used, and the corresponding energy efficient scheduling policy is obtained. The performance analysis of our proposed online algorithm based on real-world traces demonstrates that it can greatly reduce one day's electricity cost of individual BS.

• Journal of Microbiology and Biotechnology
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• 제34권5호
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• pp.1003-1016
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• 2024

This study explores the potential of plant-based decellularization in regenerative medicine, a pivotal development in tissue engineering focusing on scaffold development, modification, and vascularization. Plant decellularization involves removing cellular components from plant structures, offering an eco-friendly and cost-effective alternative to traditional scaffold materials. The use of plant-derived polymers is critical, presenting both benefits and challenges, notably in mechanical properties. Integration of plant vascular networks represents a significant bioengineering breakthrough, aligning with natural design principles. The paper provides an in-depth analysis of development protocols, scaffold fabrication considerations, and illustrative case studies showcasing plant-based decellularization applications. This technique is transformative, offering sustainable scaffold design solutions with readily available plant materials capable of forming perfusable structures. Ongoing research aims to refine protocols, assess long-term implications, and adapt the process for clinical use, indicating a path toward widespread adoption. Plant-based decellularization holds promise for regenerative medicine, bridging biological sciences with engineering through eco-friendly approaches. Future perspectives include protocol optimization, understanding long-term impacts, clinical scalability, addressing mechanical limitations, fostering collaboration, exploring new research areas, and enhancing education. Collectively, these efforts envision a regenerative future where nature and scientific innovation converge to create sustainable solutions, offering hope for generations to come.