• Title/Summary/Keyword: Granuloma

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Primary Eosinophilic Granuloma of Adult Cervical Spine Presenting as a Radiculomyelopathy

  • Bang, Woo-Seok;Kim, Kyoung-Tae;Cho, Dae-Chul;Sung, Joo-Kyung
    • Journal of Korean Neurosurgical Society
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    • v.54 no.1
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    • pp.54-57
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    • 2013
  • We report a case of 29-year-old man diagnosed as a primary eosinophilic granuloma (EG) lesion of the seventh cervical vertebra. He had paresthesia on both arms, and grasping weakness for 10 days. Cervical magnetic resonance image (MRI) showed an enhancing mass with ventral epidural bulging and cord compression on the seventh cervical vertebra. Additionally, we performed spine series MRI, bone scan and positive emission tomography for confirmation of other bone lesions. These studies showed no other pathological lesions. He underwent anterior cervical corpectomy of the seventh cervical vertebra and plate fixation with iliac bone graft. After surgical management, neurological symptoms were much improved. Histopathologic evaluation confirmed the diagnosis of EG. There was no evidence of tumor recurrence at 12 months postoperative cervical MRI follow-up. We reported symptomatic primary EG of cervical spine successfully treated with surgical resection.

Plasma cell Granuloma: one case report (혈장세포 육아종[보고 1예])

  • Kwack, Yeong-Tae;Park, Ju-Cheol;Yoo, Seh-Young
    • Journal of Chest Surgery
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    • v.14 no.3
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    • pp.225-227
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    • 1981
  • A 31-year-old female visited O.P.D. of internal medicine, Kyung Hee Medical center, with the chief complaint of generalized weakness and headache. She took a routine chest P-A and there was a 6.5 x 7.5 cm sized round mass in the right middle lung field. She admitted to the Dept. of Thoracic and Cardiovascular Surgery under the impression of malignant bronchogenic carcinoma with the remit of bronchoscopy and sputum cytology and tomogram. Middle and lower lobectomy of right lung was performed and postoperative surgical biopsy revealed out the plasma cell granuloma. The plasma cell granuloma may occur as a solitary nodule in the lung or be associated with systemic disease, plasma protein imbalance, or nonspecific local inflammatory reaction . More than two third of the reported patients were less than 30 year of age. Grossly the lesion appears reddish-brown and microscopic features include pallisade or a cartwheel distribution of plasma cells with Russel bodies and amyloid. Local excision or lobectomy has been curative in most cases.

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Eosinophilic granuloma of the mandibular condyle (하악과두에 발생한 호산구육아종)

  • Choi, Mun-Kyung;Huh, Kyung-Hoe;Yi, Won-Jin;Oh, Sung-Wook;Lee, Sam-Sun
    • Imaging Science in Dentistry
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    • v.38 no.1
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    • pp.63-67
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    • 2008
  • The present study reports a case of eosinophilic granuloma of the mandibular condyle. Eosinophilic granulomas on the mandibular condyle are very rare, but there are several common clinical and radiographic presentations. The clinical presentations involve swelling on preauricular area, limitation of opening, TMJ pain, etc. The radiographic presentations involve radiolucent lytic condylar lesion with or without pathologic fracture. Sometimes new bone formations are observed. The purpose of the article is to add new cases to the literatures.

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Protocollagen Proline Hydroxylase Activity in the Course of Rebound of Proliferative Inflammation (증식성 염증의 재증식과정에 따른 Protocollagen Proline Hydroxylase의 활성)

  • 신국현
    • YAKHAK HOEJI
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    • v.19 no.4
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    • pp.234-239
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    • 1975
  • Protocollagen proline hydroxylase (PPH) activity in the course of rebound of rat carrageenin granuloma was assyed to investigate its relationship with collagen blosynthesis. The specific activity of PPH which was inhibited significantly by treatments with hydrocortisone acetate 93mg/kg/day, 3days) was recovered near to the normal level by 48hr after the cessation of the corticoid treatments. The total enzyme activity of the granuloma of treated group was not yet recovered even on the 3rd day, still showing a significant difference from control. PPH activity expressed in terms of granuloma cells between control and the drug treated group, however, was changed showing no apparent difference throughout the experimental period. These results suggested that the synthesis of protocollagen(collagen precursor) rather than PPH activity was directly affected by administration and withdrawal of corticoid.

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A Case of Acute Poststreptococcal Glomerulonephritis Associated with Chronic Granulomatous Disease (만성 육아종 질환에 동반된 급성 연쇄상 구균 감염 후 사구체 신염 1례)

  • Kim Hyung-Tae;Seo Jung-Wook;Kim Han-Seong;Lee Chong-Guk
    • Childhood Kidney Diseases
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    • v.7 no.2
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    • pp.217-222
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    • 2003
  • Chronic granulomatous disease(CGD) is a rare inherited disorder of phagocytic cells which results in a susceptibility to infections by catalase-positive bacteria and fungi, as well as granuloma formation. And acute poststreptococcal glomerulonephritis(APSGN) is one of the most common glomerular lesions of gross hematuria in children. We experienced a case of APSGN accompanied with CGD presenting with a liver granuloma.

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Cholesterol Granuloma in the Sphenoid Sinus - A Case Report - (접형동에 발생한 콜레스테롤 육아종 - 증례보고 -)

  • Kim, Sang Su;Moon, Seong Keun;Kim, Tae Young
    • Journal of Korean Neurosurgical Society
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    • v.30 no.7
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    • pp.921-924
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    • 2001
  • The authors report a case of cholesterol granuloma in the sphoid sinus in 54-year old woman, which is probably the first report of cholesterol granuloma arising primarily in the sphenoid sinus apart from the petrous bone. The initial clinical presentations were unilateral decreased visual acuity and facial sensory change. The mass was removed totally via transsphenoidal route and the pathological examination revealed cholesterol clefts and chronic granulomatous changes. The differences between the present case and the previous reports are discussed.

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Orocutaneous fistulas of odontogenic origin presenting as a recurrent pyogenic granuloma

  • Lee, Jin Hoon;Oh, Jae Wook;Yoon, Sung Ho
    • Archives of Craniofacial Surgery
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    • v.20 no.1
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    • pp.51-54
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    • 2019
  • Orocutaneous fistulas, or cutaneous sinuses of odontogenic origin, are uncommon but often misdiagnosed as skin lesions unrelated to dental origin by physicians. Accurate diagnosis and use of correct investigative modalities are important because orocutaneous fistulas are easily confused for skin or bone tumors, osteomyelitis, infected cysts, salivary gland fistulas, and other pathologies. The aim of this study is to present our experience with a patient with orocutaneous fistulas of odontogenic origin presenting as recurrent pyogenic granuloma of the cheek, and to discuss their successful treatment.

Fatal vocal cord granuloma after orthognathic surgery

  • Park, Si-Yeon;Choi, Hong Seok;Yoon, Ji-Young;Kim, Eun-Jung;Yoon, Ji-Uk;Kim, Hee Young;Ahn, Ji-Hye
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.18 no.6
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    • pp.375-378
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    • 2018
  • Endotracheal intubation is commonly associated with laryngeal injury that often resolves spontaneously without any complication. However, stenosis or granulomatous lesions are generally found on the tracheal wall or vocal process at the tube cuff level, caused by excessive cuff pressure. We present a case of fatal vocal cord granuloma leading to dyspnea following orthognathic surgery and sustained intubation for 14 hours.

Central Giant Cell Granuloma of the Mandible: A Case Report (하악에 발생한 중심성 거대세포육아종의 치험례)

  • Chung, Jin-Wook;Oh, Deuk-Young;Seo, Je-Won;Moon, Suk-Ho;Lee, Jung-Ho;Rhie, Jong-Won;Ahn, Sang-Tae;Kim, Chang-Hyun
    • Archives of Plastic Surgery
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    • v.37 no.5
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    • pp.691-694
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    • 2010
  • Purpose: Central giant cell granuloma is a rare, benign giant cell tumor which commonly develops in areas near the teeth. It accounts for approximately less than 7% of benign tumors of the mandible. Clinically, central giant cell granuloma is classifed into aggressive and non-aggressive type, and usually requires surgical treatment. There has been no report of central giant cell granuloma in plastic surgery field of the country, and we report a case with a brief review of the diagnosis and treatment of the disease. Methods: A 23-year-old male presented with a hard, non-tender, growing mass with the size of $4.0{\times}3.0\;cm$ on mandible for several months. Computed tomography scan showed a solid mass within thinned outer cortex on mandible. The thinned outer cortex was excised with the mass and the inner cortex was partially removed burring. After the tumor removal, mandible was fixed by reconstruction plate. Results: Pathologic report showed numerous large multinucleated giant cells, diffusely distributed in a background of ovoid-to-spindle-shaped mononuclear cells. There was no evidence of recurrence after 1 year follow up. Bony defect was regenerated and we removed the reconstruction plate. Conclusion: Removal of central giant cell granuloma results in defect of outer cortex, which can be reconstructed by using reconstruction plate, autologous bone graft or bone cement. We used reconstruction plate as a conservative method to induce secondary healing of the outer cortical defect area, which resulted in normal mastication and occlusion with no recurrence.

Combination Radiation and Steroid Therapy for Midline Granuloma (Midline Granuloma의 방사선 치료 및 Steroid병용요법)

  • 강현영;박준식
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.14.3-15
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    • 1981
  • Midline Granulcma(Malignant midline reticulosis) of upper respiratory tract was known as one of the fatal diseases that involve the nasal cavity, paranasal sinuses, pharynx and larynx, with progressive localized necrotizing inflammation and granuloma formation. The disease was first described in 1897 by McBride and after Stewart many clinical and histological studies have been done in 1933. But its etiology is still unclear and therapeutic methods are still under development. The authors carried out a clinical study of 15 cases which were diagnosed and treated as midline granuloma, including 7 cases which received combination radiation and steroid therapy from January 1964 to December 1980. The results are as follows: 1) Age and Sex distribution: 6 cases fell into the ages from 30 to 39 years: 13 cases (87%) were male and 2 cases (13%) were female. 2) Primary lesion sites were nasal cavity and paranasal sinuses area (8 cases: 53%), palatine tonsil (3 cases: 20%) and pharynx (2 cases: 13%) in order. 3) Common symptoms were nasal stuffiness and sore throat (6 cases: 40%), headache (5 cases: 33%), nasal discharge and facial edema (3 cases: 20%) in order. 4) Microorganisms were identified in 4 cases: staphylococcus in 2 cases, pseudomonas in 1 case and streptococcus in 1 case. 5) All 7 cases who received combination radiation and steroid therapy revealed complete regression and no recurrence. 6) Among the 5 cases, who received steroid and antibiotic therapy, 2 cases died and other 3 cases improved temporarily and then developed aggrevation of symptoms.

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