• 한국식품영양과학회지
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• 제21권3호
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• pp.231-240
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• 1992

식이속의 단백질농도가 피리딘계 제초제인 gramoxone의 독성발현에 어떤 영향을 미치는가를 알기 위해 Wistar계 흰쥐 수놈 36마리 (6~7주령)를 6개의 실험사료군으로 나누어 2주간 사육하며 그 미치는 영향을 조사하였다. 체중증가 상황은 각단백-gramoxone군들의 경우 각 정상단백군에 비해 저조하였으며 저단백-gramoxone군에서 제일 심하였고 고단백-gramoxone군에서는 유의한 차가 없었다. 간의 지질함량변화는 각단백-gramoxone군들의 경우, 고단백-gramoxone군을 제외하고 각 단백군에 비해 증가하는 경향을 나타내었으며 특히 저단백-gramoxone군에서 가장 심하였다. 간장내 TBA가는 정상단백군, 저단백군, 고단백군 및 고단백-gramoxone군 사이에는 유의차가 없었으나 정상단백-gramoxone군과 저단백-gramoxone군의 경우 전자의 실험군들에 비해 매우 높았다. 정상단백군 및 고단백군의 간에서는 유의한 형태적인 변화가 없었으나 저단백군과 각단백-gramoxone군들에서는 정도의 차이는 이었으나 간조직의 변화가 나타났으며 간세포 지방변화 및 Kupffer 세포의 숫적인 증가가 관찰되었다. 특히 간세포 지방변화는 저단백-gramoxone군에서 심하였고 고단백-gramoxone군에서는 현저하지않았다. 간세포의 glycogen함량은 각단백-gramoxone군들에서 타군들에 비해 증가하는 경향을 보였으며 저단백-gramoxone군에서 제일 심하였다. 제일심하였다.

• 한국식품영양과학회지
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• 제22권6호
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• pp.823-832
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• 1993

This study was made to determine alleviating effects of vitamin C(Vt C) on the gramoxone toxicity in rats with respect to the growth gain, feed effeciency ratio, total lipid contents, lipid peroxication and protein patterns in rat liver. Growth gain, feed efficiency ratio and liver weight in the gramoxone group were decreased significantly as compared with the control group, while those values obtained in the gramoxone-Vt C group were increased as compared with the gramoxone group. Lipid contents and TBA value of rat liver of the gramoxone group were increased significantly as compared with the control group. However, those values of the gramoxone+Vt C group were decreased as compared with the gramoxone group. No significant differences were observed in the liver protein patterns between the gramoxone and the control group. The contents of liver protein were decreased significantly in the gramoxone group fed for 2 weeks as compared with the control group. The change of the liver protein patterns, such as the decrease of high molecular weight protein and the increase of low molecular weight protein were observed in the gramoxone+Vt C group.

• 한국식품영양과학회지
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• 제23권3호
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• pp.380-386
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• 1994

흰쥐의 간조직에 미치는 gramoxone 독성과 비타민 C의 완화효과에 대해 조사하였다. Gramoxone처리군에서 간세포의 혼탁종창과 지방변화가 사육기간이 증가함에 따라 현저하고 혼탁종창보다는 지방변화가 더 현저하였으며, 특히 간소엽의 문맥야주변대 간세포에서 지방변화가 심하였다. Kupffer세포의 수도 증가하여 4주 사육군에서 제일 많이 증가하였다. Gramoxone-비타민 C 처리군에서 간세포의 혼탁종창과 지방변화가 현저히 감소하였다. 간세포의 glycogen 함량은 정상대조군에 비해 gramoxone처리군에서 다소 증가하는 경향을 나타내었으며 특히 지방변화가 많이 일어난 간세포에서 glycogen 함량이 더 많았다. Gramoxone-비타민 C 처리군에서 gramoxone처리군에 비해 간세포의 glycogen 함량이 감소하는 경향을 나타내었다.

• 한국식품영양과학회지
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• 제23권3호
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• pp.387-395
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• 1994

The effect of vitamin C on th egramoxone toxicity in the duodenal globlet cells of rats were investigated suing histochemical methods. Rats in control, gramoxone and gramoxone+vitmain C (Vt.C) group, aged 6 to 7 weeks, were fed 18% casein diet. In th egramoxone group, neutral and acid mucins of the globlet cells in villi and crypts of duodenum tended to decrease as compared with the control group. And the globle cells secreting nonsuphated mucins tended to increase in number, being usually accompanied by a decrease of the globlet cells secreting suphated mucins which are prominent in the duodenal mucosa of control group. However, the goblet cells secreting nonsuphated mucins tended to increase in the gramoxone + Vt.C group. Morphological changes of the globlet cells in the gramoxone group were noted vacuolation and demolition of globlet cells, while those changes were not significant in the gramoxone +Vt. C group. It seems to be that Vt. C has alleviating effects on the gramoxone toxicity in secretion and production of the duodenal goblet cells.

• 한국환경과학회지
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• 제1권2호
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• pp.1-13
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• 1992

Physiological toxic and mutagenic effects of gramoxone in Drosophila melanogaster were invetigated. Gramoxone was highly toxic on the development, resulting in of lowering the viability and in prolongation of the developmental times. Adults treated with gramoxone during the developmental stages caused a lowering of the productivity and a little chinge in protein quantity. But the effect on the sex-linked lethal mutagenesis was found to be negative. The order of mortality causing ado리t stoa형e feeding to gramoxone in the D. melanogaster complex was like this ; D. mauritiana, D. sechellia, D. simulans and D. melanogasteu Two species of the D. yakuba complex were alike. Those results were more or less correlation with speciation of the D. melanogaster subgroup.

• 한국초지조사료학회지
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• 제14권1호
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• pp.7-12
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• 1994

This study was undertaken to evaluate the effect of legume reseeding on legume establishment, dry matter yield, quality and botanical composition of grasses in timothy(Ph1eum prarense L.) dominated pasture at alpine area. Establishment number and percentage of legume in timothy dominated pasture were increased with spring, red clover(Tr$olium pratense L.) and gramoxone $treatment Dry matter yield of pasture was increased with fall and grazing after overseeding, but, there waq no difference in legume species. Crude protein content(%) of grasses at the first cutting was increased with red clover and paraquat (gramoxone) treatment. Based on the results, it is suggested that spring in seeding time, red clover in legume species and oveneeding after gramoxone treatment are good for effective renovation of timothy dominated pasture at alpine area.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1994년도 한국생물과학협회 학술발표대회
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• pp.151.2-151
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• 1994

No Abstract, See Full Text

• 한국초지조사료학회지
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• 제11권2호
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• pp.46-46
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• 1991

Adequate regrowth control of weeds and shrubs has been one of the important problem for pasture establishment by overseeding on reclaimed forest hilly land. This experiment was carried out on sloping shrub land near Anseong, Gyeonggido to evaluate the effects of herbicide application on growth control of native weeds, shrubs and trees. We evaluated 63 different weeds and wood species in the trials, which are grown common in korean forest. Buthidazol and 4 other herbicides (sodium chlorate, glyphosate, U-46 and gramoxone) were sprayed each at two application rates during the period of the most intensive growth, on 20 July 45 days before overseeding of pasture species. Glyphosate and sodium chlorate gave excellant control of growth of all species. However. Uncus effusus, Carex heterostachya, Polygonatum humile, Rubus corchorifolius, Lonicera coeralea and Rhododendron mucronulatum were classified as a tolerant weed and wood species to herbicides. Herbicide buthidazol showed also successive control of regrowth of weeds and wood species. But buthidazol was evaluated as a none available herbicide for use in pasture establishment. because o! their long persist of toxic herbicide residue in soils after treatments. Herbicide U-46 and gramoxone had almost no effect on regrowth of shrubs and tree species

• 한국초지조사료학회지
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• 제11권2호
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• pp.76-83
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• 1991

Adequate regrowth control of weeds and shrubs has been one of the important problem for pasture establishment by overseeding on reclaimed forest hilly land. This experiment was carried out on sloping shrub land near Anseong, Gyeonggido to evaluate the effects of herbicide application on growth control of native weeds, shrubs and trees. We evaluated 63 different weeds and wood species in the trials, which are grown common in korean forest. Buthidazol and 4 other herbicides (sodium chlorate, glyphosate, U-46 and gramoxone) were sprayed each at two application rates during the period of the most intensive growth, on 20 July 45 days before overseeding of pasture species. Glyphosate and sodium chlorate gave excellant control of growth of all species. However. Juncus effusus, Carex heterostachya, Polygonatum humile, Rubus corchorifolius, Lonicera coeralea and Rhododendron mucronulatum were classified as a tolerant weed and wood species to herbicides. Herbicide buthidazol showed also successive control of regrowth of weeds and wood species. But buthidazol was evaluated as a none available herbicide for use in pasture establishment. because o! their long persist of toxic herbicide residue in soils after treatments. Herbicide 1:-46 and gramoxone had almost no effect on regrowth of shrubs and tree species.

• Food Science and Biotechnology
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• 제15권6호
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• pp.993-996
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• 2006

Cyanidin 3-glucoside (C3G) isolated from black rice was investigated for hepatoprotective effects in HepG2 cells under oxidative stress. When an increase in the production of reactive oxygen species (ROS) was induced by gramoxone, cell viability was drastically decreased by 42%. However, in the presence of C3G, no hepatocytic damage was observed in HepG2 cells treated with gramoxone. C3G was found to manifest a stronger scavenging effect (91%) on superoxide anion radical ($O_2\;^{.-}$) than any of the other natural and synthetic antioxidants. Results suggest that C3G from black rice possesses hepatoprotective effects in vitro, which may be, at least in part, due to $O_2\;^{.-}$ scavenging.