• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5199-5203
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• 2015

Background: Helicobacter pylori (H.pylori) is associated with chronic gastritis, peptic ulcers, gastric adenocarcinomas and mucosa associated tissue lymphomas. Cytotoxin associated gene A (CagA) is one of the virulence factors of H.pylori. It is hypothesized that reactive oxygen species (ROS) play roles in H.pylori associated disease especially in development of gastric adenocarcinoma. Individuals infected with H.pylori bearing CagA produce more ROS than others. 8-hydroxydeoxyguanosine (8OHdG) is an in vitro marker of DNA damage and oxidative stress. The aim of this study was to investigate the relationship between 8OHdG level, H.pylori infection and CagA and alterations of serum 8OHdG level after H.pylori eradication. Materials and Methods: Patients admitted with dyspeptic complaints and upper gastrointestinal endoscopy were assessed. H.pylori was determined from histopathology of specimens. Serum 8OHdG levels of three groups (H.pylori negative, H. pylori positive CagA negative and H.pylori positive CagA positive) were compared. Patients with H.pylori infection received eradication therapy. Serum 8OHdG levels pretreatment and posttreatment were also compared. Results: In total, 129 patients (M/F, 57/72) were enrolled in the study. Serum 8OHdG level of H.pylori negative, H. pylori positive CagA negative and H.pylori positive CagA positive groups were significantly different ($5.77{\pm}1.35ng/ml$, $5.43{\pm}1.14ng/ml$ and $7.57{\pm}1.25ng/ml$ respectively, p=0.05). Furthermore, eradication therapy reduced serum 8OHdG level ($6.10{\pm}1.54ng/ml$ vs $5.55{\pm}1.23ng/ml$, p=0.05). Conclusions: Individuals infected with H.pylori bearing CagA strains have the highest serum 8OHdG level and eradication therapy decreases the serum 8OHdG level. To the best of our knowledge this is the first study that evaluated the effect of CagA virulence factor on serum 8OHdG level and the effect of eradication therapy on serum 8OHdG levels together. Eradication of CagA bearing H.pylori may prevent gastric adenocarcinoma by decreasing ROS. 8OHdG level may thus be a good marker for prevention from gastric adenocarcinoma.

• 한국과학교육학회지
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• 제36권4호
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• pp.657-668
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• 2016

본 연구의 목적은 예비 과학교사들이 교육실습 과정동안 겪는 딜레마를 탐색하여 딜레마의 특징과 대응방법을 통해 교사교육에의 시사점을 알아보는 것이다. 이를 위해 사범대 과학교육전공 4학년에 재학 중인 34명의 예비 과학교사들에게 교육실습 동안 경험한 딜레마에 대해 실습기간동안 작성한 딜레마 성찰일지 131편을 수집하여 분석하였다. 분석 결과, 첫째, 예비 과학교사들이 인식하는 딜레마는 크게 '어떤 교사가 될 것인가', '어떤 수업을 해야 하는가', '어느 권력을 따라야 하는가', '어떤 인간관계를 형성해야 하는가', '교육실습생이란 어떤 사람인가' 라는 다섯 가지의 주제와 연결되어 있었다. 둘째, 예비과학교사들이 교육실습과정에서 부딪히는 딜레마는 교육실습생이라는 모호한 지위가 딜레마를 더 심화시키거나 소극적으로 대응하도록 하는 것으로 나타났다. 셋째, 예비 과학교사들의 딜레마 상황에 대한 대응방법을 분석한 결과, 딜레마 상황에서 대해 단순한 양자택일 상황으로 인식하여 조율과 협상의 전략을 시도하는 노력이 부족하며, 과학교육 전문성에 연결시키는 수준이 높지 않았다. 넷째, 예비 과학교사들의 딜레마 중 과학 교과의 특징이 확연히 드러난 것들은 과학탐구 지도에 관련된 딜레마와 과학교수학습 모형의 적용에 대한 딜레마였다. 이 밖에도 본 연구결과가 교사교육에 주는 시사점을 결과와 함께 논의하였다.

• 대한지구과학교육학회지
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• 제12권2호
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• pp.165-173
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• 2019

본 연구의 목적은 토의 토론 중심 과학수업이 과학적 개념 습득 및 과학교수효능감에 미치는 효과를 알아보는데 있다. 연구의 대상은 B 교육대학교의 2학년 학생 27명을 대상으로 연구집단을 구성하였다. 토의 토론 중심을 활용한 과학수업을 위해 2015 개정교육과정을 분석하여 지구와 우주영역인 '태양계와 별', '지구와 달의 운동', '계절의 변화' 단원에서 20개의 과학개념을 추출하였다. 그리고 과학주제를 토의 토론 중심 과학수업 12차시로 나누었으며, 12주간의 실험처치를 하였다. 연구집단에 사전-사후검사로 과학개념 검사, 과학교수효능감 검사를 하였다. 토의 토론 중심 과학수업을 통해 자연스럽게 과학개념의 습득과 과학교수효능감이 향상될 수 있도록 연구절차를 설정하여 연구를 진행하였다. 이에 대한 연구 결과는 다음과 같다. 첫째, 초등예비교사들의 토의 토론 중심 과학수업은 과학개념 습득에 효과가 있었다. 둘째, 초등예비교사들의 토의 토론 중심 과학수업이 과학교수효능감 함양에 효과가 있었다. 셋째, 초등예비교사들의 토의 토론 중심 과학수업에 대한 인식 변화를 분석한 결과 참가한 학생 대부분이 토의 토론 중심의 과학수업에 대해 긍정적으로 인식하고 있었다. 이러한 연구 결과를 통하여 토의 토론 중심 과학수업이 초등예비교사들의 과학 개념 습득 및 과학교수효능감에 긍정적인 영향을 미친다는 것을 확인할 수 있다.

• 한국수학교육학회지시리즈A:수학교육
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• 제51권2호
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• pp.145-160
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• 2012

Prospective teachers need to have an opportunity to critically examine their initial perception with regard to effective mathematics instruction during the teacher education period. This study analyzed the perception in relation to good mathematics instruction by a total of 265 prospective teachers from four institutes for elementary teacher education using a survey. The results of this study showed that the pre-service teachers regarded learner, teaching and learning method, selection of content, and construction of curriculum as important for high-quality mathematics instruction. However, they revealed relatively low levels of agreement against the importance of instructional materials, classroom environment and atmosphere, and assessment. On the basis of teachers' perception on each element of effective mathematics instruction, this paper raises issues for discussion and includes some implications for teacher education.

• 영어어문교육
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• 제11권2호
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• pp.35-50
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• 2005

Thirty six EFL freshman students at the College of Languages and Translation, King Saud University, Riyadh, Saudi Arabia were given a dictation, a listening comprehension test and a decoding test. The purpose of the study was to find out whether EFL freshmen students' spelling ability correlates with their listening comprehension and decoding skills. Data analysis showed that the typical EFL freshman student misspelled 41.5% of the words on the dictation, gave 49.5% correct responses on the listening comprehension test, and 52% correct responses on the decoding test. The median and mean scores showed that the subjects' spelling, listening and decoding achievement is low, which implied that the subjects were having spelling, listening comprehension and decoding difficulties. The students' spelling errors and correct listening comprehension and decoding responses revealed strong correlations between spelling ability, listening comprehension and decoding skills. This means that good spelling ability in EFL is related to good listening comprehension and good decoding skills. The better the listening comprehension and decoding abilities, the fewer the spelling errors. When listening comprehension and decoding skills are poor, spelling ability is also poor. Recommendations for spelling, listening and decoding instruction are given.

• 한국임상수의학회지
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• 제25권3호
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• pp.218-220
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• 2008

A 1.4 kg adult great homed owl was presented to the University of Missouri-Columbia Veterinary Teaching Hospital after being found by the side of the highway. Physical examination revealed soft tissue injuries to the left wing and leg, and good body condition (body score 4/5). The radiographs revealed comminuted fracture of the diaphysis of the left tibiotarsus (severe) and ulna (mild). Closed reduction of the fracture was performed to the left tibiotarsus and ulna. System combining an intramedually (IM) Kirschner pin, IM Kirschner pin for external skeletal fixation, and polymethylmethacrylate was used for fracture repair. At 13 weeks, radiographs revealed that bridging callus was well formed over cortices of the fracture area. No physical, behavioral, or other assessable impairment was found during the rehabilitation period.

• 논리연구
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• 제13권2호
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• pp.83-116
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• 2010

이 글에서 우리는 토론 교육 특히 공학도를 위한 토론 교육에 필요한 논리 교수 학습 모형 을 제공한다. 이를 위하여 먼저 기존에 사용되고 있는 토론 관련 교재의 논증 개념과 논증 모형을 비판적으로 검토한다. 다음으로 토론에 필요한 기본 논증과 이에 대한 훈련 모형을 제공한다. 마지막으로 이공계 학생들 특히 공대 학생들을 위한 논증 방식 특히 토론에 사용될 논증 방식으로 가설 추론과 최선의 선택으로의 추론 모형을 제공한다.

• Korean Journal of Mathematics
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• 제17권4호
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• pp.349-359
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• 2009

As students have been familiar to Internet or media which has big visual effects rather than letters, they preferred the class in computer lab to theoretical class. The class in computer lab showed all the students good reactions in concern and interest. Statistics achievements of high level students in 2008 became better than that in 2007 but those of low level students became worse than that in 2007. I analyze the reason why the achievements of low level students have become worse. The purpose of this study is to supplement of the trouble of the class in computer lab and find out a better teaching and develop mathematics education's satisfaction and qualification.

• 한국환경교육학회지:환경교육
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• 제18권2호
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• pp.101-112
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• 2005

The purpose of this study is to develop environmental inquiry activities for teaching the 10th grade students in science classes of high school. The activities are developed to perform goals of environmental education for sustainable development. In order to this, activities are sequently organized in order of context of laboratory, field, and problem solving in respect of one learning topic. The object of inquiry activities in laboratory context is understanding concepts related environment and environmental pollution. The inquiry activities in field context have an object of attaining good awareness and attitude toward environment. Throughout the activities in probem solving context students are expected to have a mind of participating in environmental issues. The activities are designed to learn and use integrated science knowledge in many domains. Some activities are intended to utilize MBL(Microcomputer-based Laboratory). The ICT materials, lesson plans, instructional sheets for teaching and student' sheets for inquiry were produced to guide these activities. It is expected that this effort will contribute to cultivate environmental literate persons who have not only scientific understanding but also practical will of environmental issues.

• 한국가정과교육학회지
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• 제11권1호
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• pp.89-102
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• 1999

Kimchi is an important traditional fermented food a korean eating habbit. It is an outstanding food to supply its taste, dietary fiber, vitamins and inorganic substances by microorganism. And recently Kimchi has spotlighted as an international food. To make study of contents concerned Kimchi, analyzed the girl’s high school economics textbook, made questionnaires about necessity of Kimchi education, practiced process of Kimchi to present how to pickle vegetables into Kimchi. The results were： 1. The most of the respondents wanted for Kimchi making and answered that they prepare Kimchi at home by themselves. 2. The most suitable pickling time was about 4 hours and salting conditions by dry and wet styles were 20% for good taste and nutrition of Kimchi. 3. Teaching-learning program by cooperative learning model developed.