• Title/Summary/Keyword: Glycoside

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Variation of Diarylheptanoid from Alnus sibirica Fitch. Ex Turcz. Processed Enzymatic Hydrolysis (효소분해에 따른 물오리나무 Diarylheptanoid 화합물의 함량 변화)

  • Wang, Hye Soo;YIN, JUN;Hwang, In Hyeok;Lee, Min Won
    • Korean Journal of Pharmacognosy
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    • v.49 no.4
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    • pp.336-340
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    • 2018
  • Alnus sibirica Fisch. ex Turcz.(AS) geographically distributes in Korea, Japan, Northeast China and Russia. The bark of Alnus species have been used as traditional medicine for the treatment of allergic skin diseases. The content evaluation of compounds which were isolated from the barks of A. sibirica processed enzymatic hydrolysis(EAS); hirsutanonol(1), 5-O-methylhirsutanonol(2), rubranol(3), hirsutenone(4) and muricarpone B(5) was conducted using HPLC. Consequently, in EAS, the content of glycoside was decreased considerably. But the aglycones(1, 3 and 4) were increased highly and 2, 5 were formed newly.

Studies on the constituents of the aerial part of Gastrodia elata Blume

  • Qian, Liu-Xiang;Back, Wan-Sook;An, Deok-Gyun;Choi, Ho-Young;Yook, Chang-Soo
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.390.1-390.1
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    • 2002
  • Gastrodia elata Blume belongs to Orchidaceae, its steamed and dried rhizomes are very important herbal medicines used for the medical treatment of headaches. migraine. dizziness, epilepsy, rheumatism. neuralgia. paralysis and other neuralgic and nervous disorders. Although phytochemical studies of the rhizome have revealed the presence of several phenolic compounds. in which a phenolic glycoside. gastrodin (C13H18O7). is a major consituent, so far, there is no report on the studies of its aerial part. (omitted)

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Hepatoprotective Effects of the Acteoside on Carbon tetrachloride \ulcornerInduced Liver Damage in Mice

  • Oh, Deuk-Hee;Lee, Kyung-Jin;Woo, Eun-Rhan;Choi, Chul-Yung;Jeong, Hye-Gwang
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.175.1-175.1
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    • 2003
  • The protective effects of acteoside, a phenylethanoid glycoside, on carbon tetrachloride-induced hepatotoxicity and the possible mechanisms involved in this protection were investigated in mice. Pretreatment with acteoside prior to the administration of carbon tetrachloride significantly prevented the increased serum enzymatic activities of alanine and aspartate aminotransferase in a dose-dependent manner. (omitted)

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Antioxidant Activity of Cercis chinensis and Its Protective Effect on Skin Aging

  • Na, Min-Kyun;Bae, Ki-Hwan;Hong, Nam-Doo;Miwa, Nobuhiko
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.66.3-67
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    • 2003
  • Reactive oxygen species are capable of damaging biomolecules such as lipids, proteins, and DNA, which can not only lead to various diseases, but also oxidative damage resulting aging. In our previous study, Cercis chinensis (Leguminosae) showed a potent antioxidant activity. Twenty compounds including a new flavonol glycoside were isolated through antioxidant activity-guided fractionation. C. chinensis and some of the constituents exhibited a potent antioxidant activity on the free radicals and lipid peroxidation and a notable protective effect on the t-BuOOH induced oxidative damage. (omitted)

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Catechin-7-O-$\beta$-D-apiofuranoside: An Anti-inflammatory constituent from alnus japonica bark

  • Jeong, Choon-Sik;Kang, Min-Hee;Hyun, Jin-Ee;Lim, Duk-Yun
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.191.3-192
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    • 2003
  • Alnus japonica (Betulaceae) has been traditionally used for purifying blood, and curing feces containing blood, enteritis, diarrhea, alcoholism and cut wounds. In the current work, activity guided isolation of the butanol fraction of the Alnus japonica bark led to the isolation of catechin-7-O-${\beta}$-D-apiofuranoside. Anti-inflammatory activity was determined with carrageenan-induced paw edema in mice as an acute inflammation, complete Freund's adjuvant-induced arthritis as a chronic inflammation. Carrageenan- induced paw edema in mice was significantly inhibited at 0.5, 1, 2, and 3 hr after carrageenan injection by administration of the flavonoid glycoside at the dose of 150mg/kg. (omitted)

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Studies on Biological Activity of Wood Extractives(XII) - Antimicrobial and Antioxidative Activities of Extractives from the Heartwood of Prunus Sargentii (2) - (수목추출물의 생리활성에 관한 연구(XII) - 산벚나무 심재 추출성분의 항균 및 항산화활성(2) -)

  • Lee, Hak-Ju;Lee, Sung-Suk;Choi, Don-Ha
    • Journal of the Korean Wood Science and Technology
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    • v.31 no.4
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    • pp.16-23
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    • 2003
  • Four flavonoids were isolated from the heartwood of Prunus sargentii. The structures were identified by NMR spectroscopic analysis: prunetin as isoflavone, angophorol, and sakuranetin as flavanone, and isosakuranin as flavanone glycoside. However, these compounds indicated low antifungal and antioxidative activities. In this regard, it could suggest that high antifungal and antioxidative activities of extractives of P. sargentii have no ralationship with these compounds.

Studies on Biological Activity of Wood Extractives(XIV) - Antifungal activity of isoflavonoids -

  • Park, Youngki;Lee, Sung-Suk;Lee, Hak-Ju;Choi, Don-Ha
    • Journal of the Korean Wood Science and Technology
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    • v.31 no.3
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    • pp.70-76
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    • 2003
  • Five isoflavonoids, biochanin A-7-O-β-D-xylopyranosyl-(1⟶6)-β-D-gluco- pyranoside (1), (-)-maackiain (2), calycosin (3), trifolirhizin (4) and genistein (5), were tested for antifungal activity against nine fungi. These compounds were isolated from the wood (compound 1 and 2) and from the bark (compound 3, 4 and 5) of S. japonica. According to the results of antifungal activity test, (-)-maackiain was evaluated as the best antifungal compound among the isolated compounds. In this regard, it could be mentioned that high antifungal activity of S. japonica wood extracts was originated from (-)-maackiain.

Extractives from Fruits of Amorpha Fruticosa (I)

  • Lee, Hyun-Jung;Lee, Hak-Ju;Kwon, Yeong-Han;Choi, Don-Ha;Paik, Ki-Hyon
    • Journal of the Korean Wood Science and Technology
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    • v.31 no.6
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    • pp.8-14
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    • 2003
  • This study was carried out identify extractives of Amorpha fruticosa. In this study, one flavonoid glycoside, one ester and two rotenoids were isolated from fruits of A. fruticosa. The structures were determined as: kaempferol 7-O-α-L-rhamnopyranoside (I), methyl 3, 4, 5-trihydroxybenzoate (methyl gallate, II), tephrosin (III) and dalbinol (IV), respectively, on the basis of spectroscopic data.

Triterpenoids from the Flower of Viburnum opulus var. clavescens for. sterile (불두화(Viburnum opulus var. clavescens for. sterile) 꽃의 트리테르페이드 성분)

  • Choi, Seong Yeon;Kim, Myong Jo;Chun, Wanjoo;Kwon, Yongsoo
    • Korean Journal of Pharmacognosy
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    • v.53 no.3
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    • pp.133-137
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    • 2022
  • Four known triterpenoids and one sterol glycoside were isolated from Viburnum opulus var. clavescens for. sterile flowers. By the spectral data analysis, we determined to be the structures of isolated compounds as 𝛼-amyrin (1), ursolic aldehyde (2), maslinic acid (3), ursolic acid (4) and 𝛽-sitosterol-3-O-glucoside (5). Among the isolated compounds, we revised 13C-NMR chemical shifts of ursolic aldehyde (2) using DEPT and HMBC spectra analysis. 𝛼-Amyrin (1), ursolic aldehyde (2), maslinic acid (3) and 𝛽-sitosterol-3-O-glucoside (5) were isolated for the first time from this plant.

Diterpene Glycosides from the Aerial Parts of Inula britannica var. chinensis Regel (금불초 지상부의 Diterpene 배당체 성분)

  • Kim, Dae Keun;Kim, Jun Hyeong
    • Korean Journal of Pharmacognosy
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    • v.53 no.1
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    • pp.16-20
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    • 2022
  • Five ent-kaurane type diterpene glycosides were isolated from the aerial parts of Inula britannica var. chinensis Regel (Compositae) through repeated column chromatography. Their chemical structures were elucidated as 16β-H-ent-kauran-19-oic acid-19-O-β-D-glucopyranoside (1), 16β-hydroxy-17-acetoxy-ent-kauran-19-oic acid-19-O-β-D-glucopyranoside (2), 16β,17-dihydroxy-ent-kauran-19-oic acid-19-O-β-D-glucopyranoside (3), 16α,17-dihydroxy-ent-kauran-19-oic acid-19-O-β-D-glucopyranoside (4) and 17-O-β-D-glucopyranosyl-16β-H-ent-kauran-19-oic acid-19-O-β-D-glucopyranoside (5), respectively, by spectroscopic analysis. Among these compounds, 1-4 were isolated for the first time from this plant.