• 한국소음진동공학회논문집
• /
• 제16권7호
• /
• pp.712-719
• /
• 2006

This paper is concerned with the comparison of substructure synthesis methods based on global and local coordinates. The substructure synthesis methods based on the global coordinates were first proposed for the dynamic analysis of complex structure and the substructure synthesis method based on the local coordinates was proposed to solve the dynamic problem of tree-like structure. However, the conceptual difference between two methods in solving the dynamic problem has never been explained. In this paper, a structure consisting of two beams is considered to show the conceptual difference of two methods. The dynamic formulation shows the characteristics and differences of two methods explicitly. The procedure for choosing proper substructure modes in each method is also explained in detail. In addition, the advantage of the substructure synthesis method based on the local coordinate system is discussed based on the numerical example. Numerical examples show how two methods are applied to the addressed problem.

• 대한약학회:학술대회논문집
• /
• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
• /
• pp.163.4-164
• /
• 2003

Peptide deformylase (PDF) is essential and unique to bacteria for cytoplasmic protein synthesis, but not required in eukaryotes, thus making it an attractive target for the discovery of novel antibacterial drugs. Protein synthesis in eubacteria, under normal conditions, is initiated by formyl-methionyl-tRNA. PDF removes the formyl-group of N- formylmethionine of newly synthesized polypeptides to produce a mature protein. In this study, a pdf gene from Staphylococcus aureus 6538p was cloned in pET-14b vector and transformed in Escherichia coli BL21 (DE3). (omitted)

• International Journal of Advanced Culture Technology
• /
• 제7권2호
• /
• pp.195-200
• /
• 2019

Media art, which is a combination of media technology and art, is making a lot of progress in combination with AI, IoT and VR. This paper aims to meet people's needs by creating a video that simulates the dance moves of an object that users admire by using media art that features interactive interactions between users and works. The project proposed a universal image synthesis system that minimizes equipment constraints by utilizing a deep running-based Skeleton estimation system and one of the deep-running neural network structures, rather than a Kinect-based Skeleton image. The results of the experiment showed that the images implemented through the deep learning system were successful in generating the same results as the user did when they actually danced through inference and synthesis of motion that they did not actually behave.

• 한국식품영양학회지
• /
• 제30권2호
• /
• pp.371-377
• /
• 2017

Muscle atrophy is characterized by a decrease in the mass of the muscle. With an increase in life expectancy and chronic illnesses, the incidence of muscle atrophy is increasing and the quality of life of patients is decreasing. Thus, reducing muscle atrophy is of high clinical and socio-economic importance. Mistletoe is a semi-parasitic plant that has been used as a traditional medicine in many countries to treat various human illnesses. It has been reported that Korean mistletoe extract (KME) has diverse biological functions including anti-tumor, anti-oxidant, anti-diabetic, anti-obesity properties, and extension of lifespan. Especially, we have recently reported that KME improves exercise endurance in mice, indicating its beneficial roles in enhancing the capacity of skeletal muscle. In this study, we investigated whether KME could activate the signaling pathway related to protein synthesis in a mouse model of muscle atrophy. Interestingly, KME efficiently activated the Akt/mTOR pathway, and Akt and mTOR are important signaling hub molecules for the acceleration of protein synthesis in muscle cells. In addition, KME also increased the activity of S6 kinase which is involved in the regulation of muscle cell size. Moreover, the ERK activity, required for transcription of ribosomal RNA for protein synthesis, was also enhanced in KME-treated mouse muscle. These data support the idea that KME increases muscle mass via increased protein synthesis. Our findings also suggest that Korean mistletoe might be a promising candidate for the development of functional foods that are beneficial for preventing muscle atrophy.

• 한국가시화정보학회지
• /
• 제12권1호
• /
• pp.49-53
• /
• 2014

In this study, a novel FDR-SPC is first synthesized in this study. The drag reducing functional radical such as PEGMA (Poly(ethylene) glycol methacrylate) has been utilized to participate in the synthesis process of the SPC. The types of the baseline SPC monomers, the molecular weight and the mole fraction of PEGMA were varied in the synthesis process. The resulting SPCs were coated to the substrate plates for the subsequent hydrodynamic test for skin friction measurement. In a low-Reynolds number flow measurement using PIV (Particle Image Velocimeter), a significant reduction in Reynolds stress was observed in a range of specimen, with the maximum drag reduction being 15.9% relative to the smooth surface.

• 제어로봇시스템학회논문지
• /
• 제9권10호
• /
• pp.832-835
• /
• 2003

The objective of this study is to investigate the possibility of chemical process synthesis purely based on mathematical programming when given an objective, feed conditions, product specifications, and model equations for available process units. A method based on a state space approach is proposed, and applied to an example problem with a reactor, a heat exchanger, and a separator. The results indicate that a computer can automatically synthesize an optimal process without any heuristics or expertise in process design provided that global optimization techniques are improved to be suitable for large problems.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2004년도 ICCAS
• /
• pp.1870-1873
• /
• 2004

The objective of this study is to investigate the possibility of chemical process synthesis purely based on mathematical programming when given an objective, feed conditions, product specifications, and model equations for available process units. A method based on a state space approach is proposed, and applied to an example problem with a reactor, a heat exchanger, and a separator. The results indicate that a computer can automatically synthesize an optimal process without any heuristics or expertise in process design provided that global optimization techniques are improved to be suitable for large problems.

• Genomics & Informatics
• /
• 제16권4호
• /
• pp.30.1-30.6
• /
• 2018

There is urgent need for effective and cost-efficient data storage, as the worldwide requirement for data storage is rapidly growing. DNA has introduced a new tool for storing digital information. Recent studies have successfully stored digital information, such as text and gif animation. Previous studies tackled technical hurdles due to errors from DNA synthesis and sequencing. Studies also have focused on a strategy that makes use of 100-150-bp read sizes in both synthesis and sequencing. In this paper, we a suggest novel data encoding/decoding scheme that makes use of long-read DNA (~1,000 bp). This enables accurate recovery of stored digital information with a smaller number of reads than the previous approach. Also, this approach reduces sequencing time.

• 한국음향학회지
• /
• 제38권5호
• /
• pp.614-620
• /
• 2019

본 논문은 전역 스타일 토큰(Global Style Token, GST)을 사용하는 종단 간(end-to-end) 감정 음성 합성 시스템의 성능을 높이기 위해 각 감정의 스타일 벡터를 효과적으로 결정하는 방법을 제안한다. 기존 방법은 각 감정을 표현하기 위해 한 개의 대푯값만을 사용하므로 감정 표현의 풍부함 측면에서 크게 제한된다. 이를 해결하기 위해 본 논문에서는 k-평균 알고리즘을 사용하여 다수의 대표 스타일을 추출하는 방법을 제안한다. 청취 평가를 통해 제안 방법을 이용해 추출한 각 감정의 대표 스타일이 기존 방법에 비해 감정 표현 정도가 뛰어나며, 감정 간의 차이를 명확히 구별할 수 있음을 보였다.

• 한국광학회지
• /
• 제20권6호
• /
• pp.319-327
• /
• 2009

본 논문에서는 다음과 같은 관점의 광각 2군 줌 렌즈 설계를 소개한다. 먼저전역최적화의 개념을 기초설계단계에서 도입하고, 이를 통해 현대의 수많은 데이터들을 체계적으로 계통화하고 단순화할 수 있는 설계방안을 제안한다. 구체적인 방안으로 전역설 계를 위해 전역구조함수라는 새로운 개념의 함수를 도입하였고 단순화시켰으며, 나아가 약간의 대수적인 혹은 수치적인 계산을 통해 전역 해 영역을 구하였다. 전역 해 영역은 전역최적화에 대응되는 개념이고 상용화된 설계프로그램들 보다 더 체계적이고 통찰적인 설계방향을 제시한다.