• Proceedings of the Korean Society of Applied Pharmacology
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• 1998.11a
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• pp.195-195
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• 1998

Ginkgetin was previously reported as an inhibitor of group II phospholipase A$_2$. It also inhibited in vitro arachidonate release from the activated macrophages and lymphocyte proliferation. These previous studies suggested an anti-inflammatory nature of ginkgetin, especially on chronic inflammation. In fact, ginkgetin showed potent anti-inflammatory activity against rat adjuvant-induced arthritis, a chronic inflammatory animal model, with comparable analgesic activity. In order to investigate the action mechanisms, tumor necrosis factor and interferone release were studied from human PMMC. It was found that ginkgetin clearly inhibited release of these cytoknes from human PMMC. Ginkgetin was also found to inhibit immunoglobulin M production at 1 - 10 uM. These results may contribute to antiarthritic activity of ginkgetin in vivo.

• YAKHAK HOEJI
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• v.41 no.1
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• pp.111-116
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• 1997

The neurotoxicity induced by L-glutamate in primary cultures of rat cortical cells could be attenuated by sesquiterpene constituent of Ginkgo biloba leaves, bilobalide. At the c oncentration of 100 nM, Bilobalide elevated the combined levels of reduced/oxidized glutathione in rat cortical cells exposed to 100 ${\mu}$M glutamate. Furthermore, bilobalide promoted a reduction in superoxide dismutase activity in glutamate-treated cells. Finally, bilobalide markedly inhibited the production of malondialdehyde. a measure of lipid peroxidation, in glutamate-treated rat cortical cells.

• The Korean Journal of Mycology
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• v.47 no.3
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• pp.187-197
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• 2019

Ascomycota is the largest phylum of the Fungi, including approximately 6,600 genera. They are often isolated from soils, indoor air, and freshwater environments, but also from plants as pathogens or endophytes. In this study, four species of Ascomycota (two of Cladosporium and one of each Daldinia and Nigrospora) were collected from the leaves of four woody plants (Camellia japonica, Ginkgo biloba, Quercus sp., Vitis vinifera). Their cultural characteristics were investigated on five different media (PDA, V8A, CMA, MEA, CZA) at 3 days after incubation at $25^{\circ}C$ in darkness. BLASTn search and phylogenetic analysis were performed using the internal transcribed spacer (ITS) rDNA sequences, in addition to tef1 gene sequences for Cladosporium species. Based on the cultural, morphological, and phylogenetic data, the isolates were identified as Cladosporium anthropophilum, Cladosporium pseudocladosporioides, Daldinia eschscholtzii, and Nigrospora chinensis. Previously, some members of Cladosporium and Nigrospora have been recorded as endophytes inhabiting the leaves and stems of various plants, whereas Daldinia eschscholtzii is a wood-inhabiting endophyte or wood-decaying fungus. To our knowledge, this is the first report of these four ascomycetes in Korea.

• Korean Journal of Environmental Agriculture
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• v.15 no.4
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• pp.472-478
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• 1996

It was conducted to compare the availabilities of parameters for evaluating the sink capacity of the broad leaves trees such as Acer saccharium, Ailanthus altissima, Ginkgo biloba, Platanus occidentalis and Salix pseudolasiogyne. These trees, repoted as resistant species to air pollutants, were exposed to $SO_2$, $NO_2$ and CO within a phytotron at $25^{\circ}C$ with 70% of relative humidity. Since the amount of ad- or absorbed gas does not always agree with the amount of accumlated pollutants in leaves and with the stomatal density, it is assumed that the amount of ad- or absorbed gas is the most basal index to evaluate the sink capacity of trees. The stomatal diffusive resistance, which has a good agreement with the amount of ad- or absorbed gas, is also available for evaluating the sink capacity of broad leaves trees.

• Korean Journal of Agricultural and Forest Meteorology
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• v.7 no.2
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• pp.141-147
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• 2005

This study investigated air pollutant levels and physiological variation of Ginkgo biloba in Chuncheon. The results were as follows: The annual average concentrations of $SO_2,\;NO_2\;and\;PM10$ were 0.004ppm, 0.013 ppm and $66{\mu}g/m^3$, respectively. The volume weighted average concentrations of ionic components were $SO_4\;^{2-}\;3.584 mg/m^3,\;NO_3^-\; 2.803 mg/m^3,\;Cl^-\;1.485 mg/m^3\;and\;NH_4\;^+\;0.998 mgg/m^3$ in precipitation. The annual wet deposition amount of the major ions was shown to be $SO_4^{2-}\;3.865g/m^2/yr,\;NO_3^-\;2.924g/m^2/yr,\;Cl^-\;2.773g/m^2/yr\;and\; NH_4\;^+\;1.485 g/m^2/yr$ during this study period. The seasonal averaged pH in leaves were spring pH 5.9 0.5, summer pH 5.5 0.4 and fall pH 5.1 0.3. The seasonal average water soluble sulfur content in leaves were spring 0.012 0.004%, summer $0.012\;0.002\%\;and\;fall\;0.020\;0.007\%$. The seasonal average water soluble sulfur content in bark were spring $0.0071\;0.0003\%,\;summer\; 0.0066\;0.0004\%,\;fall\;0.0063\;0.0004\%\;and\;winter\;0.0071\;0.0003\%$.

• Korean Journal of Ecology and Environment
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• v.46 no.2
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• pp.234-240
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• 2013

Increasing global $CO_2$ concentration and temperature is leading to the phenomenon of global warming and impacting the growth of plants. In order to determine the effects of global warming on the woody plants of Korea, five woody species, Pinus densiflora (Korea's dominant species), Ginkgo biloba (a commonly used street tree), Quercus glauca (dominant species in sub-tropical forests), Quercus gilva and Abeliophylum distichum (both endangered species), were grown at control (ambient $CO_2$+ambient temperature) and treatment (elevated $CO_2$+elevated temperature) conditions in a glasshouse, and were monitored for their ecological response. Shoot lengths and number of leaves were measured once a month from April to October in 2010, and were again measured in November 2011. Shoot lengths of P. densiflora, G. biloba and Q. glauca were not significantly affected by elevated $CO_2$ and temperature conditions. However. those of Q. gilva and A. distichum were both higher for plants grown under treatment than for those grown under control. The number of leaves of five woody species was not significantly affected by elevated $CO_2$ and temperature. These results indicate that P. densiflora, G. biloba and Q. glauca react more favorably than Q. gilva and A. distichum (each of which are designated as endangered plants) under global warming situations.

• Korean journal of applied entomology
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• v.39 no.2
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• pp.83-87
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• 2000

This study was carried out to investigate the life history of Paralebeda plagifera femorata in 1998 and 1999. Ginkgo biloba was newly known to be a host plant for the species in this study. The moth has one generation a year. It overwinted as 6th instar larva on branches of the host plant. The 9th instar larva made a rough cocoon by webbing two or three leaves, and pupated on the branch on late June. The moths emerged from early July through early August with a peak around late July. A female oviposited 205 eggs on an average on the branch, twig, or leaf margin.

• Archives of Pharmacal Research
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• v.29 no.6
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• pp.503-507
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• 2006

Flavonoids are known as natural anti-inflammatory agents. In this investigation, an anti-inflammatory potential of new topical preparation (SK Ato $Formula^{\circledR}$) containing flavonoid mixtures from Scutellaria baicalensis Georgi roots and Ginkgo biloba L. leaves with an extract of Gentiana scabra Bunge roots was evaluated in an animal model of chronic skin inflammation. Multiple 12-O-tetradecanoylphorbol-13-acetate treatments for 7 consecutive days on ICR mouse ear provoked a chronic type of skin inflammation: dermal edema, epidermal hyperplasia and infiltration of inflammatory cells. When topically applied in this model, this row formulation $(5-20\;{\mu}L/ear/treatment)$ reduced these responses. Furthermore, it inhibited prostaglandin $E_2$ generation (17.1-33.3%) and suppressed the expression of proinflammatory genes, cyclooxygenase-2 and $interleulin-1{\beta}$ in the skin lesion. Although the potency of inhibition was lower than that of prednisolone, all these results suggest that Ato $Formula^{\circledR}$ may be beneficial for treating chronic skin inflammatory disorders such as atopic dermatitis.

• Korean Journal of Environmental Agriculture
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• v.18 no.2
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• pp.116-121
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• 1999

Tree leaves have been used as the passive sampler to measure lipophilic PAHs in the atmosphere. This is a convenient and economical method in case of sampling at many regions including the remote places that are not supplied with electric power. But poor results can be obtained if samples are collected carelessly or PAHs concentrations are calculated on the basis of wrong natures of tree leaves. This study was performed to avoid the errors of interpretation that can be induced by these problems when tree leaves are used as a passive sampler of PAHs. Conclusions have been reached as follows: 1) The correlativity was low among the water content, the lipid content, the dry weight and the area of four kinds of tree leaves. According to this, PAHs concentrations calculated per wet weight, dry weight, lipid content and area of tree leaves differed. Therefore, same unit shoud be used to describe concentrations of the pollutants when PAHs concentrations deposited on leaves from atmosphere in the different regions are compared. It is better to decribe the unit as PAHs concentrations per dry weight of leaves for comparison with other data because almost researcher make use of this unit, and the range of fluctuation of the dry weights in several natures of tree leaves was relatively little during growing seasons. 2) Although four kinds of trees(Pinus Koraiensis, Ginkgo biloba, Evodia daniellii, Kalopanax pictus) had been grown at the same place, PAHs concentrtions deposited on leaves differed respectively. Therefore PAHs concentrations deposited on different kinds of tree leaves should not be compared. It is better to make use of pine needles as the sample because pine trees grow almost over the world, and it is able to collect their samples in winter.

• Journal of Korean Society of Forest Science
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• v.82 no.4
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• pp.328-336
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• 1993

This study was conducted to investigate sensitivity of tree seedlings to $SO_2$. Visible injury symptoms and changes of ethylene production were investigated in tree seedlings with the fumigation of $SO_2$ in gas chamber 4 hours a day for six days. The symptoms of visible injury did not appear below 0.5ppm level of $SO_2$ exposure but a change of visible injury with the passage of time appeared at 1.5 and 2.5ppm in all seedlings. With the higher the concentration and/or the longer exposure of $SO_2$ the visible injury symptoms on leaves increased in all seedlings. The sensitivity of seedlings to $SO_2$ was the highest in Liriodendron tulipifera followed by Pinus strobus, Ginkgo biloba, Pinus densiflora and Pinus koraiensis. The amount of ethylene production was more at 1.5 and 2.5ppm of $SO_2$ exposure than at 0.5ppm and the peak time of it came faster at higher levels. The amount of ethylene production was significantly different among tree seedlings. It showed a higher at production of ethylene in Liriodendron tulipifera compared to Ginkgo biloba and the ethylene production of Pinus trees to $SO_2$ were the highest in Pinus strobus followed by Pinus densiflora and Pinus koraiensis. In needle of Pinus strobus the ethylene production increased with the increasing rate of visible injury until the injury rate of 40-50% and than decreased with the increasing rate of visible injury since the rate of 50%.