• 대한정형외과학회지
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• 제56권6호
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• pp.525-529
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• 2021

건활막 거대세포종은 관절 내에 드물게 발생하는 병변으로 양측 슬관절 내에 발생하는 경우는 국소형보다는 미만형에서 많은 것으로 알려져 있다. 따라서 양측 슬관절 내에 발생한 국소형 건막 거대세포종을 보고하는 문헌은 제한되어 있으며 특히 슬개대퇴간 동통을 초래한 양측에 발생한 국소형 건활막 거대세포종의 국내 보고는 없었다. 저자들은 양측 슬관절 전방부의 동통을 초래한 건활막 거대세포종 증례를 관절경하에서 절제 후 병리학적으로 확진 하였으며 임상적으로 좋은 결과를 보였기에 문헌고찰과 함께 보고하고자 한다.

• 대한족부족관절학회지
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• 제6권1호
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• pp.117-120
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• 2002

We experienced 1 case of the giant cell tumor of the tendon sheath penetrating the middle phalanx of the third toe. Patient had painless huge mass all around the third phalanx of the foot which made a penetrating hole through the middle phalanx of the third toe in plain radiography. The period from the onset of the symptom until operation was about several years. The mass extended to the base of the distal phalanx and compressed digital nerves and vessels. Patient presented with a chief complaint of the pain on the plantar aspect of the toe and limitation of the motion of the distal interphalangeal joint. Giant cell tumor of the tendon sheath was cured by total en block resection.

• 대한관절경학회지
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• 제15권2호
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• pp.113-116
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• 2011

후방십자인대에 발생한 국소적 거대세포종의 보고는 드물며, 불완전한 절제 시 재발율이 매우 높다. 저자들은 슬관절 후방십자인대에 발생한 국소적 거대 세포종 1예를 관절경하에서 후격막 통과 도달법을 통해 완전 절제 후 병리학적으로 확진하였으며, 1년 추시에서 양호한 임상적 결과를 보여 이를 문헌고찰과 함께 보고하는 바이다.

• Journal of Korean Neurosurgical Society
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• 제30권10호
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• pp.1229-1232
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• 2001

A rare case of tenosynovial giant cell tumor of invading left temporomandibular joint(TMJ) extending the middle cranial fossa is reported. Report of this entity in the temporomandibular joint is rare. A 39-year old male patient presented with mild discomfort and swelling in preauricular area. MR image demonstrated a destructive lesion of the left TMJ, with bony erosion of temporal bone and extension into middle cranial fossa. The patient underwent radiotherapy as adjuvant therapy to prevent recurrence, followed by resection. The histological and radiological features of this tumor are discussed along with a brief description of the disease entity.

• 대한영상의학회지
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• 제83권2호
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• pp.406-413
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• 2022

악성 건초 거대세포종은 매우 드물며 양성 거대 세포 종양 이후 발생하거나 함께 발생할 수 있다. 저자들은 임파종을 가진 73세 남자 환자에서 왼쪽 무릎의 표재성 연부 종양으로 나타난 드문 악성 거대 세포 종양에 대해 보고한다.

• 대한세포병리학회지
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• 제1권1호
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• pp.93-97
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• 1990

Two cases of giant cell tumor of bone diagnosed by fine needle aspiration cytology are described. Case 1 was a 28-year-old male who had pain sense for one year at the right distal thigh. His radiologic finding revealed a destructive cortical lesion with soft tissue extension at medial side of epiphysis of the distal femur. Case 2 was a 21-year-old female complaining pain at left distal forearm for eight months and showed a well-demarcated expansile osteolytic lesion with multiseptation, and cortical destruction at epiphysis and metaphysis of the left distal radius on the X-ray. Fine needle aspiration of each lesion was performed. The aspirate of the case 1 revealed moderate cellularity, which was composed of scattered giant cells of osteoclastic type and small round to oval monotonous stromal cells in large areas. Giant cells were evenly distributed in single or small groups and had irregular but abundant cytoplasms with 10 to 20 nuclei in the center. The nuclei showed ovoid shape, fine granular chromatin, and a small but conspicuous nucleolus. Stromal cells were dispersed in isolated pattern or sometimes aggregated in clusters and showed the same nuclei as those of giant cells and scanty cytoplasms. Comparing to case 1, case 2 had a more translucent abundant cytoplasm in the giant cells and more spindled stromal cells. All two cases revealed neither nuclear atypism nor increased abnormal mitoses In both giant and stromal cells, suggesting no evidence of malignancy. Thereafter the lesions were treated with excision and curettage, and histologically confirmed as giant cell tumors of the bone.

• Journal of Korean Neurosurgical Society
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• 제29권4호
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• pp.564-568
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• 2000

The authors present a rare case of subependymal giant cell astrocytoma which successfully treated with endoscopic tumor resection. A 15-year-old boy was presented with multiple episode of generalized seizure and intermittent headache for 5 years. The patient had facial adenoma sebaceum, multiple nevi on his back, and mental retardation. Cerebral MRI scans showed a round tumor located at the frontal horn of right ventricle near the foramen monro. The tumor was totally removed with endoscopic procedure and histologically confirmed as a subependymal giant cell astrocytoma. Subependymal giant cell astrocytomas can cause all the clinical problems that are associated with other types of intracranial tumor. However, surgical indication is not well standardized, because of the lack of basic knowledge about the tumor and the likelihood of surgical morbidity. We believe that endoscopic surgery, a minimally invasive technique, can circumvent the surgical disadvantage while achieving the surgical goal.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• 제61권11호
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• pp.615-618
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• 2018

The central giant cell granuloma is a benign tumor seen generally in the mandible, but rarely in other cranial bones. Herein, we present a 51-year-old man with central giant cell granuloma in the right zygomatic bone. Physical and radiologic examinations of the central giant cell granuloma in the zygomatic bone showed that specific and preoperative diagnosis is usually difficult. Therefore, clinicians should consider the possibility that central giant cell granuloma may occur in the zygomatic bone mimicking other more frequently observed lesions.

• 대한두경부종양학회지
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• 제29권1호
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• pp.14-17
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• 2013

Giant cell reparative granuloma(GCRG) is a non-neoplastic rapidly expanding and locally destructive tumor that occurs almost exclusively within the mandible and maxilla. A 58-year-old man, complained of a mass on the left infra-auricular area starting 2 months ago. The radiologic finding suggests a mass that originate from mandible, pathology diagnosed the lesion as a giant cell reparative granuloma. The tumor was surgically excised without complications. We report the case with a review of literature.

• 대한골관절종양학회지
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• 제1권2호
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• pp.145-153
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• 1995

Giant cell tumor is most frequently found in juxtaarticular region, and difficult to treat because of local recurrence. Although primary resections reduce recurrence, the joint function will be markedly impaired. Techniques involving physical adjuncts(high speed burr and electric cauterization), acrylic cement or en bloc resection with VFG(vascularized fibular graft) have been employed to reduce local recurrence. From October 1984 to April 1994, twenty-nine patients diagnosed as giant cell tumor were treated at department of Orthopaedic Surgery, School of Medicine, Kyung Hee University. There were eleven men and 18 women, ranging in age from 17 to 52 years(mean: 34 years). The average follow-up period was four years and five months. The location of the lesion was around the knee in 15, distal radius in three, femoral head in three, and others in eight patients. Fifteen patients around the knee joint were treated with several modalities; curettage with bone graft in five, curettage with cement filling in three, curettage with bone graft and physical adjuncts in five, en bloc resection with VFG in one and en bloc resection with arthroplasty in one patient. The functional results, according to the Marshall's knee score, were excellent in one, good in two, and fair in two after the curettage with bone graft, good in three after the curettage with bone cement filling, excellent in one, good in four after the curettage with bone graft and physical adjuncts, and good in two after the en bloc resection with VFG or arthroplasty. Three patients had local recurrence among 15 patients with giant cell tumor around knee. Vascularized fibular graft around wrist joint provided good functional restoration without local recurrence in all three patients who had giant cell tumor in distal radius. Although there is no statistical significance, it seems that curettage with bone graft using physical adjuncts or acrylic cement reveals better results than simple curettage with bone graft. Excellent functional result were obtained without local recurrence by using vascularized fibular graft after en bloc resection.