• International Journal of Industrial Entomology and Biomaterials
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• 제35권2호
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• pp.89-96
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• 2017

Various health promoting effects of steamed and freeze-dried mature silkworm powder (SMSP) have been reported. However, it is not still clear which substances in SMSP are responsible for those health promoting effects yet. In this study, we examined and compared the quantities of phytochemicals in SMSP and freeze-dried mulberry leave powder (FMLP). To investigate the optimal solvent for extracting phytochemicals from SMSP and FMLP, we used four different solvents. Among them, 80% ethanol extracts from SMSP and FMLP contained the highest amount of five flavonoids examined. In addition, FMLP had high contents of flavonoids compared with those of SMSP. The amounts of rutin, isoquercetin, astragalin, quercetin, and kaempferol in FMLP were $5.078{\pm}0.187mg/g$, $5.162{\pm}0.083mg/g$, $2.989{\pm}0.061mg/g$, $3.317{\pm}0.236mg/g$, and $2.243{\pm}0.237mg/g$, respectively, while the amounts of rutin, isoquercetin, astragalin, quercetin, and kaempferol in SMSP were $0.171{\pm}0.024mg/g$, $0.252{\pm}0.032mg/g$, $0.374{\pm}0.031mg/g$, $0.645{\pm}0.063mg/g$, and $0.0512{\pm}0.047mg/g$, respectively. Taken together, SMSP could be a source for providing various and readily absorbable flavonoids.

• Journal of Ginseng Research
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• 제47권2호
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• pp.228-236
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• 2023

Background: QiShen YiQi pills (QSYQ) is a Traditional Chinese Medicine (TCM) formula, which has a significant effect on the treatment of patients with myocardial infarction (MI) in clinical practice. However, the molecular mechanism of QSYQ regulation pyroptosis after MI is still not fully known. Hence, this study was designed to reveal the mechanism of the active ingredient in QSYQ. Methods: Integrated approach of network pharmacology and molecular docking, were conducted to screen active components and corresponding common target genes of QSYQ in intervening pyroptosis after MI. Subsequently, STRING and Cytoscape were applied to construct a PPI network, and obtain candidate active compounds. Molecular docking was performed to verify the binding ability of candidate components to pyroptosis proteins and oxygen-glucose deprivation (OGD) induced cardiomyocytes injuries were applied to explore the protective effect and mechanism of the candidate drug. Results: Two drug-likeness compounds were preliminarily selected, and the binding capacity between Ginsenoside Rh2 (Rh2) and key target High Mobility Group Box 1 (HMGB1)was validated in the form of hydrogen bonding. 2 μM Rh2 prevented OGD-induced H9c2 death and reduced IL-18 and IL-1β levels, possibly by decreasing the activation of the NLRP3 inflammasome, inhibiting the expression of p12-caspase1, and attenuating the level of pyroptosis executive protein GSDMD-N. Conclusions: We propose that Rh2 of QSYQ can protect myocardial cells partially by ameliorating pyroptosis, which seems to have a new insight regarding the therapeutic potential for MI.

• 간호행정학회지
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• 제5권2호
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• pp.401-414
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• 1999

향후 더욱 경쟁적인 상황에 놓이게 될 보천의료 분야에 능동적으로 대처하기 위한 방안의 하나로서 보건의료 조직은 간호부서의 성과 향상을 위한 노력을 지속적으로 기울이고 있다. 이러한 성과 향상을 위한 노력은 정확한 성과의 측정이 함께 이루어질 때 가능하게 된다. 간호서비스의 성과 측정은 여러 각도에서 조명되고 측정이 이루어져야하며 간호관리자는 총괄적인 성과측정시스템에 대한 새로운 인식과 사전 준비작업으로 무장을 하여야 한다. 이러한 요구에 맞추어, 본 논문은 간호 서비스의 성과측정방법에 대한 고찰, 즉 생산성, 효율성, 간호의 질, 수익성. quality of work life에 대한 간호분야에서의 접근방법을 재정리하고, 새로운 총괄적인 성과측정방법의 개념을 제시한다.

• 한국주거학회논문집
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• 제7권2호
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• pp.79-89
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• 1996

In this paper, various characteristics-physiological, psychological and social peculiarities \ulcorner of the elderly are analyzed. Then planning factors of living environment are studied to grope directions on design of living spaces for the aged in the future, which is pertinent to their needs.The peculiar properties of the elderly are analyzed and planning factors of architectural spaces are studied by referring to sundry records from many branch \ulcorner gerontology, medical science, psychology, sociology, etc. \ulcorner of knowledge. In planning house for the aged, we have to consider their physiological, psychological, social characteristics and build many types of living spaces in order to meet their special needs in mind, to maintain their living styles. because their personalities, human relations, living patterns, and so forth have been formd individually for a long period of time and their present conditions are different respectively.

• 가정과삶의질연구
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• 제25권1호
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• pp.59-75
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• 2007

This review synthesizes research during the past 15 years on the family relations of older persons. After discussing two background issues-sociodemographic changes of later life families and the status of the elderly-the following topics are addressed; relationships between aged parents and adult children, couple relationships, grandparents' relationship with their grandchildren and sibling relationships. Family relationships are vital support systems providing emotional and instrumental support in the lives of older persons. Mutual assistance and affection among family members were found to be common characteristics. Although research on family gerontology has increased in quantify, there are feater needs to develop qualitative, longitudinal and theory grounded studies to capture the rich complexity of family life. Other challenges and suggestions for future research on older persons' family relationship are presented.

• 대한가정학회지
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• 제37권12호
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• pp.179-192
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• 1999

Thesedays, Home Economic in Korea is faced with the danger of a discord caused by the outer pressure of reorganization in the process educational reformation. The first purpose of this study was to examine the characteristics of the informatized society and the changes of families lived in the informatized society. The second was to assert to strengthen Home Economics in the informatized society. Ultimately we suggested an integrative and interdisciplinary model about Home Economics from the ecological and informative perspective. This model consist with three parts: Human development(Child studies, Gerontology, & Adolescent studies) and family studies division(Family relation studies, family resource management studies, & Consumer studies) Environmental division(Clothing and Textiles, Food and Nutrition, & Housing) and HEIS(Home Economics Information System). This classification is correspond with the one Human-Behavioral Environment and Human-Constructed Environment of Ecological theory.

• 한국병원경영학회지
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• 제18권4호
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• pp.39-53
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• 2013

This study purports to learn the lessons from the managerial innovation of Japanese public hospitals. The performance of three innovation strategies of Japanese public hospitals, such as managerial efficiency, restucturing and networking, and rearrnagement of governance and ownership, were analyzed and its implications for Korea were discussed. Based upon it, several strategies for improving the performance of Korean public hospitals, were suggested.

• Annals of Geriatric Medicine and Research
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• 제22권4호
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• pp.159-166
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• 2018

The Korean Geriatrics Society was founded on October 3, 1968. Over the 50 years since then, the Society has incessantly strived to stay attuned to the aging society and to achieve an increasingly greater research impact in the field of gerontology and geriatric medicine. The Society has passed through periods of preparation for a leap forward, followed by rapid growth, expansion, and maturity. As a result, the Society has gained a firm foothold at home and abroad as a leading research society for both qualitative and quantitative achievements in geriatric medicine. At this juncture, with an ultra-aging society being just around the corner, we are celebrating its 50th anniversary and anticipating our second half-century with great enthusiasm about our mission and role as a leading geriatric research organization.

• 농촌의학ㆍ지역보건
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• 제23권1호
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• pp.65-78
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• 1998

일부농촌지역 노인들의 일상생활 동작능력(Activities of Daily Living : ADL)장애의 자연사와 ADL지하에 영향을 미치는 요인을 검토하기 이해 1993년 경상북도 경주시 강동면 13개리에 거주하고 있는 60세이상 재택고령자 621명의 사전조사된 자료를 기본으로 4년간의 추적조사를 시행하여 사망자 90과 조사불능군 56명을 제외한 475명을 대상자로 선정하였으며 목욕, 옷입기, 화장실이용, 일어서기, 식사하기, 실금의 일상생활 동작능력을 조사하였다. 2) 4년간의 추적조사에서는 고ADL의 82.1%가 고ADL을 유지하였고, 저ADL의 77.8%가 4년내에 사망하였다. 3) 4년간의 ADL항목별 가능군의 장애 발생율은 목욕이 가장 많았고, 실금, 옷입기, 화장실이용, 일어서기, 식사하기의 순서로 나타났으며, 제1회 조사시 고 ADL군의 6.7%(여자의 8.1%, 남자의 4.6%)에서 4년후 장애가 발생했다. 4) ADL저하에 영향을 미치는 요인을 분석하기 위한 일반적 특성에 따른 ADL의 변화에서는 연령과 직업에 있어 유의한 차이를 보여 노화가 될수록, 현재 직업이 없는 노인일수록 ADL감소율이 높게 나타났고, 형태에 따른 ADL의 변화에서는 남자노인의 생활비 부담과 주관식 건강상태에서 유의한 차이를 보여 남자노인은 자녀가 배우자에 의존할수록, 주관적 건강상태에서는 건강하지 않다고 느낄수록 ADL저하율이 높았다.

• 한국노년학
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• 제32권2호
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• pp.431-446
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• 2012

본 연구는 노년초월 이론과 Erikson & Erikson의 9단계 이론을 소개함으로써, 고령화 시대에 접어든 우리나라에서 노화를 보다 긍정적이면서 새로운 관점에서 바라볼 수 있도록 하는 데 있다. 이를 위하여 기존에 알려진 Erikson의 인간발달 8단계의 확장이론인 Erikson & Erikson의 9단계 이론에 대해 살펴보도록 하겠다. 또한 이 이론의 가장 대표적인 현상으로 소개하는 '노년초월(Gerotranscendence)'에 대해 살펴보고, 우리나라 노년학계에서의 활용방안 등에 대하여 모색해보고자 한다. 노년초월의 개념은 Tornstam(1994)에 의해 처음 제기되었고 이후 Erikson & Erikson(1997)의 9단계이론으로 알려지게 되었다. 노년초월이란 중년기 이후 노년기에 접어든 개인이 "인생의 전반적인 시각을 물질주의적이고 합리적인 시각에서 보다 우주적이고 초월적인 시각으로 변화시키는 것"로 정의될 수 있다. 노년초월은 많은 노인들에게 나타나는 자기 초월의 자발적 과정으로서, 사회적으로 정의되는 자기(self)에게 덜 의존하게 되고, 내면성이 증가하고 이전 세대와 미래 세대와의 연결감이 더 커지는 것이다. 본 연구에서 분석한 노년초월에 대한 이론적 평가를 요약하면 다음과 같다. 첫째, 본 연구는 Erikson & Erikson의 9단계 이론과 그 대표적인 현상으로 인식되는 노년초월 이론을 처음으로 소개하여 노년학 이론의 적용범위를 확대하였다. 둘째, 노인복지 실천현장에서 노인에 대한 인식을 새롭게 할 수 있는 관점을 제공하였다. 셋째, 노년초월 이론을 우리나라에서 적용시키고 확대시킴으로써 다른 학문 분야와의 폭넓은 연구교류의 장을 마련할 수 있을 것으로 기대한다.